Single-blastocyst transfer decreases twin gestation without affecting pregnancy outcome

Fertility and Sterility

Volumn 89, Issue 6, 2008, Pages 1702-1708

  Styer, Aaron K ^a   Wright, Diane L ^a   Wolkovich, Anne M ^a   Veiga, Christine ^a   Toth, Thomas L ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

blastocyst; cryopreservation; Elective single embryo transfer; in vitro fertilization; twin gestation

Indexed keywords

ADULT; ARTICLE; BLASTOCYST; CHEMICAL ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; CRYOPRESERVATION; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; HUMAN; LIVE BIRTH; MAJOR CLINICAL STUDY; MEDICAL RECORD REVIEW; PREGNANCY OUTCOME; PRIORITY JOURNAL; RETROSPECTIVE STUDY; STATISTICAL ANALYSIS; TWIN PREGNANCY;

ADULT; EMBRYO TRANSFER; ESTRADIOL; FEMALE; FERTILIZATION IN VITRO; FOLLICLE STIMULATING HORMONE; HUMANS; INFANT, NEWBORN; INFERTILITY, FEMALE; MALE; OVARY; PREGNANCY; PREGNANCY OUTCOME; TWINNING, MONOZYGOTIC; TWINS;

EID: 44349152269     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2007.05.036     Document Type: Article

References (26)

1. Van Voorhis B.J. Outcomes from assisted reproductive technology. Obstet Gynecol 107 (2006) 183-200
2. Templeton A., and Morris JK. Reducing the risk of multiple births by transfer of two embryos after in vitro fertilization. N Engl J Med 339 (1998) 573-577
3. Jain T., Missmer S.A., and Hornstein M.D. Trends in embryo-transfer practice and in outcomes of the use of assisted reproductive technology in the United States. N Engl J Med 350 (2004) 1639-1645
4. Crosignani P.G., and Rubin B.L. Multiple gestation pregnancy. Hum Reprod 15 (2000) 1856-1858
5. Kozinsky K., Zadori J., Orvos H., Katona M., Pal A., and Kovacs L. Obstetric and neonatal risk of pregnancies after assisted reproductive technology: a matched control study. Acta Obstet Gynecol Scand 82 (2003) 850-856
6. Callahan T.L., Hall J.E., Ettner S.L., Christiansen C.L., Greene M.F., and Crowley Jr. W.F. The economic impact of multiple gestation and the contribution of assisted reproductive techniques to their incidence. N Engl J Med 331 (1994) 244-249
7. Ledger W.L., Anumba D., Marlow N., Thomas C.M., Wilson E.C.F., and the COOMBS Group. The cost to the NHS of multiple births after IVF treatment in the UK. BJOG 113 (2006) 21-25
8. Ombelet W., De Sutter P., Van der Elst J., and Martens G. Multiple gestation and infertility treatment: registration, reflection and reaction-the Belgian project. Hum Reprod Update 11 (2005) 3-14
9. Mantikainen H., Tiitinen A., Tomas C., Tapanainen J., Orava M., Tuomivaara L., et al. One versus two embryo transfer after IVF and ICSI: a randomized study. Hum Reprod 16 (2001) 1900-1903
10. Thurin A., Hausken J., Hillensjo T., Jablonowska B., Pinborg A., Strandell A., et al. Elective single-embryo transfer versus double embryo transfer in in vitro fertilization. N Engl J Med 351 (2004) 2392-2402
11. Papankiolaou E.G., Camus M., Kolibianakis E.M., Van Landuyt L., Van Steirteghem A., and Devroey P. In vitro fertilization with single blastocyst-stage versus single cleavage-stage embryos. N Engl J Med 354 (2006) 1139-1146
12. Criniti A., Thyer A., Chow G., Lin P., Klein N., and Soules M. Elective single blastocyst transfer reduces twin rates without compromising pregnancy outcomes. Fertil Steril (2005) 1613-1619
13. Pinborg A., Loft A., Schmidt A., and Andersen A.N. Attitudes of IVF/ICSI-twin mothers towards twins and single embryo transfer. Hum Reprod 18 (2003) 621-627
14. Davis O.K. Elective single embryo transfer-has its time arrived?. N Engl J Med 351 (2004) 2440-2442
15. Jonas H.A., and Lumley J. Triplets and quadruplets born in Victoria between 1982 and 1990. The impact of IVF and GIFT on rising birthrates. Med J Aust 158 (1993) 659-663
16. The ESHRE Capri Workshop Group. Multiple gestation pregnancy. Hum Reprod 15 (2000) 1856-1864
17. American Society for Reproductive Medicine. Guidelines on number of embryos transferred. Fertil Steril 82 (2004) 773-774
18. Gerris J., Neoubourg D., Mangelschots K., Van Royen E., Van de Meerssche M., and Valkenburg M. Prevention of twin pregnancy after in vitro fertilization or intracytoplasmic sperm injection based on strict embryo criteria: a prospective randomized clinical trial. Hum Reprod 14 (1999) 2581-2587
19. Gardner D.K., Phil D., Surrey E., Minjarez D., Leitz A., Stevens J., et al. Single blastocyst transfer: a prospective randomized trial. Fertil Steril 81 (2004) 551-555
20. Papanikolaou E.G., Camus M., Kolibianakis E.M., Van Landuyt L., Van Steirteghem A., and Devroey P. In vitro fertilization with single blastocyst stage versus single cleavage-stage embryos. N Engl J Med 354 (2006) 1139-1146
21. Rijnders P.M., and Jansen C.A. The predictive value of day 3 embryo morphology regarding blastocyst formation, pregnancy and implantation rate after day 5 transfer following in vitro fertilization or intracytoplasmic sperm injection. Hum Reprod 13 (1998) 2869-2873
22. Magli M.C., Jones G.M., Gras L., Gianaroli L., Korman I., and Trounson A.O. Chromosome mosaicism in day 3 aneuploid embryos that develop to morphologically normal blastocysts in vitro. Hum Reprod 15 (2000) 1781-1786
23. Straessen C., Platteau P., Van Assche E., Michiels A., Tournaye H., Camus M., et al. Comparison of blastocyst transfer with or without preimplantation genetic diagnosis for anueploidy screening in couple with advanced maternal age: a prospective randomized controlled trial. Hum Reprod 19 (2004) 2849-2858
24. Gleicher N., and Barad D. The relative myth of elective single embryo transfer. Hum Reprod 21 (2006) 1337-1344
25. Van Montfoort A.P.A., Fiddelers A.A.A., Janssen J.M., Derhaag J.G., Dirksen C.D., Dunselman G.A.J., et al. In unselected patients, elective single embryo transfer prevents all multiples, but results in significantly lower pregnancy rates compared with double embryo transfer: a randomized controlled trial. Hum Reprod 21 (2006) 338-343
26. Styer A.K., and Toth T.L. Twin gestation following in vitro fertilization: is elective single embryo transfer the realistic solution?. Postgrad Obstet Gynecol 27 (2007) 1-6