Mitotic centromere-associated kinesin is a novel marker for prognosis and lymph node metastasis in colorectal cancer

British Journal of Cancer

Volumn 98, Issue 11, 2008, Pages 1824-1829

  Ishikawa, K ^a,b   Kamohara, Y ^a,b   Tanaka, F ^b   Haraguchi, N ^a,b   Mimori, K ^a,b   Inoue, H ^a,b   Mori, M ^a,b  

^a KYUSHU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Colorectal cancer; Lymph node metastasis; MCAK; Prognosis

Indexed keywords

KINESIN; MESSENGER RNA; MITOTIC CENTROMERE ASSOCIATED KINESIN;

ARTICLE; CANCER SURVIVAL; CENTROMERE; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION; GENE SEQUENCE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CELL LINE, TUMOR; COLORECTAL NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; KINESIN; LYMPHATIC METASTASIS; MULTIVARIATE ANALYSIS; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 44349151502     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6604379     Document Type: Article

References (24)

1. Gorbsky GJ (2004) Mitosis: MCAK under the aura of Aurora B. Curr Biol 14: R346-R348
2. Helenius J, Brouhard G, Kalaidzidis Y, Diez S, Howard J (2006) The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends. Nature 441: 115-119
3. Holmfeldt P, Stenmark S, Gullberg M (2004) Differential functional interplay of TOGp/XMAP215 and the KinI kinesin MCAK during interphase and mitosis. EMBO J 23: 627-637
4. Holmfeldt P, Zhang X, Stenmark S, Walczak CE, Gullberg M (2005) CaMKIIgamma-mediated inactivation of the Kin I kinesin MCAK is essential for bipolar spindle formation. EMBO J 24: 1256-1266
5. Honore S, Pasquier E, Braguer D (2005) Understanding microtubule dynamics for improved cancer therapy. Cell Mol Life Sci 62: 3039-3056
6. Kline-Smith SL, Walczak CE (2002) The microtubule-destabilizing kinesin XKCM1 regulates microtubule dynamic instability in cells. Mol Biol Cell 13: 2718-2731
7. Kono S (1996) Dietary factors for gastrointestinal cancers: a worldwide overview. Gann Monogr Cancer Res 44: 29-39
8. Lawrence CJ, Dawe RK, Christie KR, Cleveland DW, Dawson SC, Endow SA, Goldstein LS, Goodson HV, Hirokawa N, Howard J, Malmberg RL, McIntosh JR, Miki H, Mitchison TJ, Okada Y, Reddy AS, Saxton WM, Schliwa M, Scholey JM, Vale RD, Walczak CE, Wordeman L (2004) A standardized kinesin nomenclature. J Cell Biol 167: 19-22
9. Mimori K, Mori M, Shiraishi T, Fujie T, Baba K, Haraguchi M, Abe R, Ueo H, Akiyoshi T (1997) Clinical significance of tissue inhibitor of metalloproteinase expression in gastric carcinoma. Br J Cancer 76: 531-536
10. Mori M, Barnard GF, Staniunas RJ, Jessup JM, Steele Jr GD, Chen LB (1993a) Prothymosin-alpha mRNA expression correlates with that of c-myc in human colon cancer. Oncogene 8: 2821-2826
11. Mori M, Staniunas RJ, Barnard GF, Jessup Jr JM, Steele GD, Chen LB (1993b) The significance of carbonic anhydrase expression in human colorectal cancer. Gastroenterology 105: 820-826
12. Nakamura Y, Tanaka F, Haraguchi N, Mimori K, Matsumoto T, Inoue H, Yanaga K, Mori M (2007) Clinicopathological and biological significance of mitotic centromere-associated kinesin overexpression in human gastric cancer. Br J Cancer 97: 543-549
13. Ogawa K, Utsunomiya T, Mimori K, Tanaka Y, Tanaka F, Inoue H, Murayama S, Mori M (2004) Clinical significance of elongation factor-1 delta mRNA expression in oesophageal carcinoma. Br J Cancer 91: 282-286
14. Parkin DM, Bray F, Ferlay J, Pisani P (2001) Estimating the world cancer burden: Globocan 2000. Int J Cancer 94: 153-156
15. Japanese Society for Cancer Colon and Rectum (1998) General Rules for Clinical and Pathological Studies on Cancer of the Colon, Rectum and Anus 6th edn. Tokyo: Kanehara
16. Scanlan MJ, Welt S, Gordon CM, Chen YT, Gure AO, Stockert E, Jungbluth AA, Ritter G, Jager D, Jager E, Knuth A, Old LJ (2002) Cancer-related serological recognition of human colon cancer: identification of potential diagnostic and immunotherapeutic targets. Cancer Res 62: 4041-4047
17. Schumacher P, Dineen S, Barnett Jr C, Fleming J, Anthony T (2007) The metastatic lymph node ratio predicts survival in colon cancer. Am J Surg 194: 827-831; discussion 831-822
18. Shimo A, Tanikawa C, Nishidate T, Lin ML, Matsuda K, Park JH, Ueki T, Ohta T, Hirata K, Fukuda M, Nakamura Y, Katagiri T (2008) Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis. Cancer Sci 99: 62-70
19. Tomonaga T, Matsushita K, Ishibashi M, Nezu M, Shimada H, Ochiai T, Yoda K, Nomura F (2005) Centromere protein H is up-regulated in primary human colorectal cancer and its overexpression induces aneuploidy. Cancer Res 65: 4683-4689
20. Tsukuma H, Ajiki W, Oshima A (2004) [Cancer incidence in Japan]. Gan To Kagaku Ryoho 31: 840-846
21. Vale RD, Fletterick RJ (1997) The design plan of kinesin motors. Annu Rev Cell Dev Biol 13: 745-777
22. Wittmann T, Hyman A, Desai A (2001) The spindle: a dynamic assembly of microtubules and motors. Nat Cell Biol 3: E28-E34
23. Wordeman L, Mitchison TJ (1995) Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis. J Cell Biol 128: 95-104
24. Wordeman L, Wagenbach M, von Dassow G (2007) MCAK facilitates chromosome movement by promoting kinetochore microtubule turnover. J Cell Biol 179: 869-879