Growth inhibition of human colon cancer cell line HCT116 by bis[2-(acylamino)phenyl] disulfide and its action mechanism

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 5, 2008, Pages 916-920

  Yamakawa, Satoshi ^a   Demizu, Aya ^a   Kawaratani, Yasuyuki ^a   Nagaoka, Yasuo ^a   Terada, Yuji ^a   Maruyama, Sakiko ^b   Uesato, Shinichi ^a  

^a KANSAI UNIVERSITY   (Japan)

^b NIPPON KAYAKU CO LTD   (Japan)

Author keywords

catenin T cell factor association; Apoptosis; Bis 2 (acylamino)phenyl disulfide; c Jun N terminal kinase; HCT116

Indexed keywords

ACETYLSALICYLIC ACID DERIVATIVE; ANTINEOPLASTIC AGENT; BETA CATENIN; BIS[2 (2,2 DIMETHYLPROPANOYLAMINO)PHENYL]DISULFIDE; DISULFIDE; DYE; NCX 4040; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR 7;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE; CELL PROLIFERATION; CELL STRAIN HCT116; CELL STRESS; COLON CANCER; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG SCREENING; ENZYME PHOSPHORYLATION; FIBROBLAST; HUMAN; HUMAN CELL; IC 50; NICK END LABELING;

ANILINE COMPOUNDS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZIMIDAZOLES; BETA CATENIN; BLOTTING, WESTERN; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DISULFIDES; FLOW CYTOMETRY; FLUORESCENT DYES; HCT116 CELLS; HUMANS; IMMUNOPRECIPITATION; IN SITU NICK-END LABELING; JNK MITOGEN-ACTIVATED PROTEIN KINASES;

EID: 44349132139     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.916     Document Type: Article

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