A simplified synthesis of ethyl 5-chloro-4-fluoro-1h-indole-2-carboxylate and ethyl 5-chloro-6-fluoro-1h-h-indole-2-carboxylate

Organic Preparations and Procedures International

Volumn 34, Issue 5, 2002, Pages 517-520

  Silvestri, Romano ^a   De Martino, Gabriella ^a   Sbardella, Gianluca ^b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF SALERNO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 44149103217     PISSN: 00304948     EISSN: 19455453     Source Type: Journal    
DOI: 10.1080/00304940209355772     Document Type: Article

References (12)

1. R. Silvestri, M. Artico, S. Massa, T. Marceddu, F. De Montis and P. La Colla, Bioorg. Med. Chem. Lett., 10,253 (2000);
2. M. Artico, R. Silvestri, E. Pagnozzi, B. Bruno, E. Novellino, G. Greco, S. Massa, A Ettorre, A.G. Loi, F. Scintu and P. La Colla, J. Med. Chem., 43, 1886 (2000);
3. R. Silvestri, M. Artico, G. De Martino, E. Novellino, G. Greco, A. Lavecchia, S. Massa, A. G. Loi, S. Doratiotto and P. La Colla, Bioorg. Med. Chem., 8,2305 (2000);
4. R. Silvestri, M. Artico, A. Pifferi, G. De Martino, C. Saturnino and M. Artico, Heterocycles, 53,2163 (2000).
5. B. Robinson, ‘The Fischer Indole Synthesis’, J. Wiley and Sons, Chirchester, New York, NY, 1982.
6. D. L. Hughes, Org. Prep. Proced. Int., 25,607 (1993).
7. J. W. Corbett, S. S. Ko, J. D. Rodgers, L. A. Gearhart, N. A. Magnus, L. T. Bacheler, S. Diamond, S. Jeffrey, R. M. Klabe, B. C. Cordova, S. Garber, K. Logue, G. L. Trainor, P. S. Anderson and S. K. Erickson-Viitanen, J. Med. Chem., 43,2019, (2000).
8. P. Stanetty and B. Krumpak. J. Org. Chem., 61,5130 (1996).
9. B. Heath-Brown and P. G. Philpott, J. Chem. Soc., 7185 (1965).
10. H. M. Kissman, D. W. Farnsworth and B. Witkop, J. Am. Chem. Soc., 74, 3948 (1952).
11. T. De Crow, Ree. Trav. Chim. Pays Bas, 48, 1061 (1929).
12. F. L. Allen, J. C. Brunton and H. Suschitzky, J. Chem. Soc., 1283 (1955).