Engineering channels: Atomic biology

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 17, 2008, Pages 6211-6212

  Eisenberg, Bob ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CYCLODEXTRIN; ION CHANNEL; OUTER MEMBRANE PROTEIN; OUTER MEMBRANE PROTEIN F; PROTEIN OMPG; ESCHERICHIA COLI PROTEIN; OMPG PROTEIN, E COLI; PORIN;

BIOTECHNOLOGY; CHANNEL GATING; GENE MUTATION; MOLECULAR DYNAMICS; NOTE; PRIORITY JOURNAL; PROTEIN ENGINEERING; SIMULATION; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; GENETIC PROCEDURES; PROTEIN CONFORMATION;

BACTERIAL OUTER MEMBRANE PROTEINS; BIOSENSING TECHNIQUES; COMPUTER SIMULATION; ESCHERICHIA COLI PROTEINS; ION CHANNEL GATING; MODELS, MOLECULAR; PORINS; PROTEIN CONFORMATION; PROTEIN ENGINEERING;

EID: 44049092745     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0802435105     Document Type: Note

References (22)

1. Ashcroft FM (1999) Ion Channels and Disease (Academic, New York).
2. Eisenberg B (2003) Proteins, channels, and crowded ions. Biophys Chem 100:507-517.
3. Boda D, et al. (2007) Steric selectivity in Na channels arising from protein polarization and mobile side chains. Biophys J 93:1960-1980.
4. Hille B (2001) Ionic Channels of Excitable Membranes (Sinauer, Sunderland, MA).
5. Sakmann B, Neher E (1995) Single Channel Recording (Plenum, New York).
6. Rudy B, Iverson LE, eds (1992) Ion Channels (Academic, New York).
7. Braha O, et al. (1997) Designed protein pores as components for biosensors. Chem Biol 4:497-505.
8. Bayley H (1997) Building doors into cells. Sci Am 277(3):62- 67.
9. Kang X-f, Cheley S, Rice-Ficht AC, Bayley H (2007) A storable encapsulated bilayer chip containing a single protein nanopore. J Am Chem Soc 129:4701-4705.
10. Chen M, Khalid S, Sansom MSP, Bayley H (2008) Outer membrane protein G: Engineering a quiet probe for biosensing. Proc Natl Acad Sci USA 105:6272-6277.
11. 2+ selectivity of a chemically modified OmpF with reduced pore volume. Biophys J 91:4392-4440.
12. Miedema H, et al. (2006) Conductance and selectivity fluctuations in D127 mutants of the bacterial porin OmpF. Eur Biophys J 36:13-22.
13. Vrouenraets M, Wierenga J, Meijberg W, Miedema H (2006) Chemical modification of the bacterial porin OmpF: Gain of selectivity by volume reduction. Biophys J 90:1202-1211.
14. 2+ channels. Biophys J 87:3137-3147.
15. Miedema H, et al. (2007) A biological porin engineered into a molecular, nanofluidic diode. Nano Lett 7:2886-2891.
16. Hilf RJC, Dutzler R (2008) X-ray structure of a prokaryotic pentameric ligand-gated ion channel. Nature 452:375-379.
17. Roth R, Gillespie D, Nonner W, Eisenberg B (January 30, 2008) Bubbles, gating, and anesthetics in ion channels. Biophys J, 10.1529/biophysj.107. 120493.
18. Khalid S, Bond PJ, Carpenter T, Sansom MS (2007) OmpA: Gating and dynamics via molecular dynamics simulations. Biochim Biophys Acta, in press.
19. Barthel J, Buchner R, Münsterer M (1995) Electrolyte data collection, Part 2: Dielectric properties of water and aqueous electrolyte solutions. Chemistry Data Series, ed Kreysa G (DECHEMA, Frankfurt), Vol 12.
20. Eisenberg RS (1990) Channels as enzymes. J Membr Biol 115:1-12.
21. Edsall J, Wyman J (1958) Biophysical Chemistry (Academic, New York).
22. Dixon M, Webb EC (1979) Enzymes (Academic, New York).