Neurofibromatosis type 1 (NF1) tumor suppressor, neurofibromin, regulates the neuronal differentiation of PC12 cells via its associating protein, CRMP-2

Journal of Biological Chemistry

Volumn 283, Issue 14, 2008, Pages 9399-9413

  Patrakitkomjorn, Siriporn ^a   Kobayashi, Daiki ^a   Morikawa, Takashi ^a   Wilson, Masayo Morifuji ^a   Tsubota, Nobuyuki ^a   Irie, Atsushi ^a   Ozawa, Tatsuya ^a   Aoki, Masashi ^a   Arimura, Nariko ^b   Kaibuchi, Kozo ^b   Saya, Hideyuki ^a   Araki, Norie ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL REACTIONS; CLARIFICATION; DIFFERENTIATION (CALCULUS); GALLIUM ALLOYS; NUCLEIC ACIDS; PHOSPHORYLATION; RNA; TUMORS;

CELLULAR FUNCTIONS; CELLULAR PROTEINS; COMPLEX FORMATIONS; DO-MAINS; FUNCTIONAL ASSOCIATIONS; GAP FUNCTIONS; KINASE CASCADES; NEGATIVE REGULATORS; NERVE GROWTH FACTORS; NEURITE OUTGROWTHS; NEURITES; NEUROFIBROMATOSIS; NEUROFIBROMIN; NEURONAL CELLS; NEURONAL DIFFERENTIATIONS; OVEREXPRESSION; PC12 CELLS; SMALL INTERFERING RNAS; TERMINAL DOMAINS; TUMOR SUPPRESSOR GENES; TUMOR SUPPRESSORS;

PROBABILITY DENSITY FUNCTION;

COLLAPSIN RESPONSE MEDIATOR PROTEIN 2; CYCLIN DEPENDENT KINASE 5; NERVE GROWTH FACTOR; NEUROFIBROMIN; RAS PROTEIN; RHO KINASE; SMALL INTERFERING RNA; CDK5 PROTEIN, HUMAN; CDK5 PROTEIN, MOUSE; CDK5 PROTEIN, RAT; COLLAPSIN RESPONSE MEDIATOR PROTEIN-2; CRMP2 PROTEIN, RAT; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; NERVE PROTEIN; PROTEIN P21; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; NERVE CELL; NEURITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; ANIMAL; CELL STRAIN; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; METHODOLOGY; MOUSE; NEUROFIBROMATOSIS; PATHOLOGY; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE; PROTEOMICS; RAT; UPREGULATION;

ANIMALS; CELL DIFFERENTIATION; CYCLIN-DEPENDENT KINASE 5; GLYCOGEN SYNTHASE KINASE 3; GTPASE-ACTIVATING PROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; NERVE GROWTH FACTOR; NERVE TISSUE PROTEINS; NEURITES; NEUROFIBROMATOSIS 1; NEUROFIBROMIN 1; ONCOGENE PROTEIN P21(RAS); PC12 CELLS; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEOMICS; RATS; RHO-ASSOCIATED KINASES; RNA, SMALL INTERFERING; UP-REGULATION;

EID: 44049084687     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708206200     Document Type: Article

References (42)

1. Stephens, K., Riccardi, V. M., Rising, M., Ng, S., Green, P., Collins, F. S., Rediker, K. S., Powers, J. A., Parker, C., and Donis-Keller, H. (1987) Genomics 1, 353-357
2. Cawthon, R. M., Weiss, R., Xu, G. F., Viskochil, D., Culver, M., Stevens, J., Robertson, M., Dunn, D., Gesteland, R., O'Connell, P., and White, R. (1990) Cell 62, 193-201
3. Costa, R. M., Federov, N. B., Kogan, J. H., Murphy, G. G., Stern, J., Ohno, M., Kucherlapati, R., Jacks, T., and Silva, A. J. (2002) Nature 415, 526-530
4. Guo, H. F., Tong, J., Hannan, F., Luo, L., and Zhong, Y. (2000) Nature 403, 895-898
5. Gregory, P. E., Gutmann, D. H., Mitchell, A., Park, S., Boguski, M., Jacks, T., Wood, D. L., Jove, R., and Collins, F. S. (1993) Somatic Cell Mol. Genet. 19, 265-274
6. Yunoue, S., Tokuo, H., Fukunaga, K., Feng, L., Ozawa, T., Nishi, T., Kikuchi, A., Hattori, S., Kuratsu, J., Saya, H., and Araki, N. (2003) J. Biol. Chem. 278, 26958-26969
7. Xu, H., and Gutmann, D. H. (1997) Brain Res. 759, 149-152
8. Li, C., Cheng, Y., Gutmann, D. A., and Mangoura, D. (2001) Brain Res. Dev. Brain Res. 130, 231-248
9. Ozawa, T., Araki, N., Yunoue, S., Tokuo, H., Feng, L., Patrakitkomjorn, S., Hara, T., Ichikawa, Y., Matsumoto, K., Fujii, K., and Saya, H. (2005) J. Biol. Chem. 280, 39524-39533
10. Tokuo, H., Yunoue, S., Feng, L., Kimoto, M., Tsuji, H., Ono, T., Saya, H., and Araki, N. (2001) FEBS Lett. 494, 48-53
11. Fukata, Y., Itoh, T. J., Kimura, T., Menager, C., Nishimura, T., Shiromizu, T., Watanabe, H., Inagaki, N., Iwamatsu, A., Hotani, H., and Kaibuchi, K. (2002) Nat. Cell Biol. 4, 583-591
12. Yoshimura, T., Kawano, Y., Arimura, N., Kawabata, S., Kikuchi, K., and Kaibuchi, K. (2005) Cell 120, 137-149
13. Bollag, G., McCormick, F., and Clark, R. (1993) EMBO J. 12, 1923-1927
14. Feng, L., Yunoue, S., Tokuo, H., Ozawa, T., Zhang, D., Patrakitkomjorn, S., Ichimura, T., Saya, H., and Araki, N. (2004) FEBS Lett. 557, 275-282
15. Byk, T., Dobransky, T., Cifuentes-Diaz, C., and Sobel, A. (1996) J. Neurosci. 16, 688-701
16. Byk, T., Ozon, S., and Sobel, A. (1998) Eur. J. Biochem. 254, 14-24
17. Cole, A. R., Causeret, F., Yadirgi, G., Hastie, C. J., McLauchlan, H., McManus, E. J., Hernandez, F., Eickholt, B. J., Nikolic, M., and Sutherland, C. (2006) J. Biol. Chem. 281, 16591-16598
18. Lee, S., Kim, J. H., Lee, C. S., Kim, Y., Heo, K., Ihara, Y., Goshima, Y., Suh, P. G., and Ryu, S. H. (2002) J. Biol. Chem. 277, 6542-6549
19. Dasgupta, B., and Gutmann, D. H. (2003) Curr. Opin. Genet. Dev. 13, 20-27
20. Fahsold, R., Hoffmeyer, S., Mischung, C., Gille, C., Ehlers, C., Kucukceylan, N., Abdel-Nour, M., Gewies, A., Peters, H., Kaufmann, D., Buske, A., Tinschert, S., and Nurnberg, P. (2000) Am. J. Hum. Genet. 66, 790-818
21. Minturn, J. E., Geschwind, D. H., Fryer, H. J., and Hockfield, S. (1995) J. Comp. Neurol. 355, 369-379
22. Hamajima, N., Matsuda, K., Sakata, S., Tamaki, N., Sasaki, M., and Nonaka, M. (1996) Gene (Amst.) 180, 157-163
23. Ozon, S., Byk, T., and Sobel, A. (1998) J. Neurochem. 70, 2386-2396
24. Wang, L. H., and Strittmatter, S. M. (1996) J. Neurosci. 16, 6197-6207
25. Goshima, Y., Nakamura, F., Strittmatter, P., and Strittmatter, S. M. (1995) Nature 376, 509-514
26. Hedgecock, E. M., Culotti, J. G., Thomson, J. N., and Perkins, L. A. (1985) Dev. Biol. 111, 158-170
27. Hedgecock, E. M., Culotti, J. G., Hall, D. H., and Stern, B. D. (1987) Development (Camb.) 100, 365-382
28. Desai, C., Garriga, G., McIntire, S. L., and Horvitz, H. R. (1988) Nature 336, 638-646
29. Kimura, T., Watanabe, H., Iwamatsu, A., and Kaibuchi, K. (2005) J. Neurochem. 93, 1371-1382
30. Uchida, Y., Ohshima, T., Sasaki, Y., Suzuki, H., Yanai, S., Yamashita, N., Nakamura, F., Takei, K., Ihara, Y., Mikoshiba, K., Kolattukudy, P., Honnorat, J., and Goshima, Y. (2005) Genes Cells 10, 165-179
31. Sayas, C. L., Moreno-Flores, M. T., Avila, J., and Wandosell, F. (1999) J. Biol. Chem. 274, 37046-37052
32. Luo, L. (2000) Nat. Rev. Neurosci. 1, 173-180
33. Hirose, M., Ishizaki, T., Watanabe, N., Uehata, M., Kranenburg, O., Moolenaar, W. H., Matsumura, F., Maekawa, M., Bito, H., and Narumiya, S. (1998) J. Cell Biol. 141, 1625-1636
34. Bito, H., Furuyashiki, T., Ishihara, H., Shibasaki, Y., Ohashi, K., Mizuno, K., Maekawa, M., Ishizaki, T., and Narumiya, S. (2000) Neuron 26, 431-441
35. Nakayama, A. Y., Harms, M. B., and Luo, L. (2000) J. Neurosci. 20, 5329-5338
36. Lew, J., Huang, Q. Q., Qi, Z., Winkfein, R. J., Aebersold, R., Hunt, T., and Wang, J. H. (1994) Nature 371, 423-426
37. Nikolic, M., Dudek, H., Kwon, Y. T., Ramos, Y. F., and Tsai, L. H. (1996) Genes Dev. 10, 816-825
38. Chae, T., Kwon, Y. T., Bronson, R., Dikkes, P., Li, E., and Tsai, L. H. (1997) Neuron 18, 29-42
39. Nikolic, M., Chou, M. M., Lu, W., Mayer, B. J., and Tsai, L. H. (1998) Nature 395, 194-198
40. Owen, R., and Gordon-Weeks, P. R. (2003) Mol. Cell. Neurosci. 23, 626-637
41. Cole, A., Frame, S., and Cohen, P. (2004) Biochem. J. 377, 249-255
42. Yoshimura, T., Arimura, N., Kawano, Y., Kawabata, S., Wang, S., and Kaibuchi, K. (2006) Biochem. Biophys. Res. Commun. 340, 62-68