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Volumn 47, Issue 3, 2008, Pages 153-160

Low n-6:n-3 fatty acid ratio, with fish- or flaxseed oil, in a high fat diet improves plasma lipids and beneficially alters tissue fatty acid composition in mice

Author keywords

linolenic acid; Cardiovascular; Docosahexaenoic acid; Eicosapentaenoic acid; Fish oil; Flaxseed oil; Mice

Indexed keywords

ARACHIDONIC ACID; CHOLESTEROL; CHOLESTEROL ESTER; DOCOSAHEXAENOIC ACID; FISH OIL; HIGH DENSITY LIPOPROTEIN; ICOSAPENTAENOIC ACID; LINSEED OIL; LYSOPHOSPHATIDYLCHOLINE; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLSERINE; PHOSPHOLIPID; SAFFLOWER OIL; SPHINGOMYELIN; TRIACYLGLYCEROL;

EID: 43949118754     PISSN: 14366207     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00394-008-0709-8     Document Type: Article
Times cited : (93)

References (43)
  • 1
    • 0033055142 scopus 로고    scopus 로고
    • The effects of dietary alpha-linolenic acid compared with docosahexaenoic acid on brain, retina, liver, and heart in the guinea pig
    • Abedin L, Lien EL, Vingrys AJ, Sinclair AJ (1999) The effects of dietary alpha-linolenic acid compared with docosahexaenoic acid on brain, retina, liver, and heart in the guinea pig. Lipids 34:475-482
    • (1999) Lipids , vol.34 , pp. 475-482
    • Abedin, L.1    Lien, E.L.2    Vingrys, A.J.3    Sinclair, A.J.4
  • 2
    • 14944342635 scopus 로고    scopus 로고
    • Omega-3 fatty acids improve hepatic steatosis in a murine model: Potential implications for the marginal steatotic liver donor
    • Alwayn IP, Andersson C, Zauscher B, Gura K, Nose V, Puder M (2005) Omega-3 fatty acids improve hepatic steatosis in a murine model: potential implications for the marginal steatotic liver donor. Transplantation 79:606-608
    • (2005) Transplantation , vol.79 , pp. 606-608
    • Alwayn, I.P.1    Andersson, C.2    Zauscher, B.3    Gura, K.4    Nose, V.5    Puder, M.6
  • 3
    • 10044229531 scopus 로고    scopus 로고
    • Dietary flaxseed protects against ventricular fibrillation induced by ischemia-reperfusion in normal and hypercholesterolemic rabbits
    • Ander BP, Weber AR, Rampersad PP, Gilchrist JS, Pierce GN, Lukas A (2004) Dietary flaxseed protects against ventricular fibrillation induced by ischemia-reperfusion in normal and hypercholesterolemic rabbits. J Nutr 134:3250-3256
    • (2004) J Nutr , vol.134 , pp. 3250-3256
    • Ander, B.P.1    Weber, A.R.2    Rampersad, P.P.3    Gilchrist, J.S.4    Pierce, G.N.5    Lukas, A.6
  • 4
    • 0023894099 scopus 로고
    • The influence of n-6 and n-3 fatty acids on kidney phospholipids composition and on eicosanoid production in aging rats
    • Barcelli UO, Beach DC, Pollak VE (1988) The influence of n-6 and n-3 fatty acids on kidney phospholipids composition and on eicosanoid production in aging rats. Lipids 23:309-312
    • (1988) Lipids , vol.23 , pp. 309-312
    • Barcelli, U.O.1    Beach, D.C.2    Pollak, V.E.3
  • 5
    • 25844437057 scopus 로고    scopus 로고
    • Dietary α-linolenic acid increases brain but not heart and liver docosahexaenoic acid levels
    • Barcelo-Coblijn G, Collison LW, Jolly CA, Murphy EJ (2005) Dietary α-linolenic acid increases brain but not heart and liver docosahexaenoic acid levels. Lipids 40:787-798
    • (2005) Lipids , vol.40 , pp. 787-798
    • Barcelo-Coblijn, G.1    Collison, L.W.2    Jolly, C.A.3    Murphy, E.J.4
  • 6
    • 0015979889 scopus 로고
    • The oxidative desaturation of unsaturated fatty acids in animals
    • Brenner RR (1974) The oxidative desaturation of unsaturated fatty acids in animals. Mol Cell Biochem 3:41-52
    • (1974) Mol Cell Biochem , vol.3 , pp. 41-52
    • Brenner, R.R.1
  • 7
    • 0842349501 scopus 로고    scopus 로고
    • An omega-3 polyunsaturated fatty acid concentrate increases plasma high-density lipoprotein 2 cholesterol and paraoxonase levels in patients with familial combined hyperlipidemia
    • Calabresi L, Villa N, Canavesi M, Sirtori CR, James RW, Bernini F et al (2004) An omega-3 polyunsaturated fatty acid concentrate increases plasma high-density lipoprotein 2 cholesterol and paraoxonase levels in patients with familial combined hyperlipidemia. Metabolism 53:153-158
    • (2004) Metabolism , vol.53 , pp. 153-158
    • Calabresi, L.1    Villa, N.2    Canavesi, M.3    Sirtori, C.R.4    James, R.W.5    Bernini, F.6
  • 9
    • 7644228032 scopus 로고    scopus 로고
    • Cholesterol synthesis in mice is suppressed but lipofuscin formation is not affected by long-term feeding of n-3 fatty acid-enriched oils compared with lard and n-6 fatty acid-enriched oils
    • Du C, Sato A, Watanabe S, Wu C, Ikemoto A, Ando K, Kikugawa K, Fujii Y, Okuyama H (2003) Cholesterol synthesis in mice is suppressed but lipofuscin formation is not affected by long-term feeding of n-3 fatty acid-enriched oils compared with lard and n-6 fatty acid-enriched oils. Biol Pharm Bull 26:766-770
    • (2003) Biol Pharm Bull , vol.26 , pp. 766-770
    • Du, C.1    Sato, A.2    Watanabe, S.3    Wu, C.4    Ikemoto, A.5    Ando, K.6    Kikugawa, K.7    Fujii, Y.8    Okuyama, H.9
  • 10
    • 0019159289 scopus 로고
    • The effect of dietary supplementation of fish oil on experimental myocardial infarction
    • Culp BR, Lands WE, Lucches BR, Pitt B, Romson J (1980) The effect of dietary supplementation of fish oil on experimental myocardial infarction. Prostaglandins 20:1021-1031
    • (1980) Prostaglandins , vol.20 , pp. 1021-1031
    • Culp, B.R.1    Lands, W.E.2    Lucches, B.R.3    Pitt, B.4    Romson, J.5
  • 11
    • 33747128489 scopus 로고    scopus 로고
    • Mechanisms for the hypotriglyceridemic effect of marine omega-3 fatty acids
    • Davidson MH (2006) Mechanisms for the hypotriglyceridemic effect of marine omega-3 fatty acids. Am J Cardiol 98:27i-33i
    • (2006) Am J Cardiol , vol.98
    • Davidson, M.H.1
  • 12
    • 0034748162 scopus 로고    scopus 로고
    • Relation between dietary linolenic acid and coronary artery disease in the National Heart, Lung, and Blood Institute Family Heart Study
    • Djousse L, Pankow JS, Eckfeldt JH, Folsom AR, Hopkins PN, Province MA, Hong Y, Ellison RC (2001) Relation between dietary linolenic acid and coronary artery disease in the National Heart, Lung, and Blood Institute Family Heart Study. Am J Clin Nutr 74:612-619
    • (2001) Am J Clin Nutr , vol.74 , pp. 612-619
    • Djousse, L.1    Pankow, J.S.2    Eckfeldt, J.H.3    Folsom, A.R.4    Hopkins, P.N.5    Province, M.A.6    Hong, Y.7    Ellison, R.C.8
  • 15
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animals
    • Folch J, Les M, Sloane-Stanley GH (1957) A simple method for the isolation and purification of total lipids from animals. J Biol Chem 226:497-509
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Les, M.2    Sloane-Stanley, G.H.3
  • 16
    • 0032974045 scopus 로고    scopus 로고
    • Dietary omega-3 polyunsaturated fatty acids from fish oil reduce interleukin-12 and interferon-gamma production in mice
    • Fritsche KL, Byrge M, Feng C (1999) Dietary omega-3 polyunsaturated fatty acids from fish oil reduce interleukin-12 and interferon-gamma production in mice. Immunol Lett 65:167-173
    • (1999) Immunol Lett , vol.65 , pp. 167-173
    • Fritsche, K.L.1    Byrge, M.2    Feng, C.3
  • 17
    • 0028837184 scopus 로고
    • Cytokine secretion and eicosanoid production in the peripheral blood mononuclear cells of MS patients undergoing dietary supplementation with n-3 polyunsaturated fatty acids
    • Gallai V, Sarchielli P, Trequattrini A, Franceschini M, Floridi A, Firenzi C, Alberti A, Di Benedetto D, Stragliotto E (1995) Cytokine secretion and eicosanoid production in the peripheral blood mononuclear cells of MS patients undergoing dietary supplementation with n-3 polyunsaturated fatty acids. J Neuroimmunol 56:143-153
    • (1995) J Neuroimmunol , vol.56 , pp. 143-153
    • Gallai, V.1    Sarchielli, P.2    Trequattrini, A.3    Franceschini, M.4    Floridi, A.5    Firenzi, C.6    Alberti, A.7    Di Benedetto, D.8    Stragliotto, E.9
  • 18
    • 0036668195 scopus 로고    scopus 로고
    • Blood pressure response to fish oil supplementation: Meta-regression analysis of randomized trial
    • Geleijnse JM, Giltay EJ, Grobbee DE, Donders AR, Kok FJ (2002). Blood pressure response to fish oil supplementation: meta-regression analysis of randomized trial. J Hypertens 20:1493-1499
    • (2002) J Hypertens , vol.20 , pp. 1493-1499
    • Geleijnse, J.M.1    Giltay, E.J.2    Grobbee, D.E.3    Donders, A.R.4    Kok, F.J.5
  • 19
    • 0031809489 scopus 로고    scopus 로고
    • Can adults adequately convert alpha-linolenic acid (18:3n-3) to eicosapentaenoic acid (20:5n-3) and docosahexaenoic acid (22:6n-3)?
    • Gerster H (1998) Can adults adequately convert alpha-linolenic acid (18:3n-3) to eicosapentaenoic acid (20:5n-3) and docosahexaenoic acid (22:6n-3)? Int J Vitam Nutr Res 68:159-173
    • (1998) Int J Vitam Nutr Res , vol.68 , pp. 159-173
    • Gerster, H.1
  • 20
    • 31544465901 scopus 로고    scopus 로고
    • The dietary alpha-linolenic acid to linoleic acid ratio does not affect the serum lipoprotein profile in humans
    • Goyens PL, Mensink RP (2005) The dietary alpha-linolenic acid to linoleic acid ratio does not affect the serum lipoprotein profile in humans. J Nutr 135:2799-804
    • (2005) J Nutr , vol.135 , pp. 2799-804
    • Goyens, P.L.1    Mensink, R.P.2
  • 21
    • 31544469205 scopus 로고    scopus 로고
    • Flaxseed oil increases the plasma concentrations of cardioprotective (n-3) fatty acids in humans
    • Harper CR, Edwards MJ, DeFilipis AP, Jacobson TA (2006) Flaxseed oil increases the plasma concentrations of cardioprotective (n-3) fatty acids in humans. J Nutr 136:83-87
    • (2006) J Nutr , vol.136 , pp. 83-87
    • Harper, C.R.1    Edwards, M.J.2    Defilipis, A.P.3    Jacobson, T.A.4
  • 22
    • 33746040070 scopus 로고    scopus 로고
    • Why do omega-3 fatty acids lower serum triglycerides?
    • Harris WS, Bulchandani D (2006) Why do omega-3 fatty acids lower serum triglycerides? Curr Opin Lipidol 17:387-393
    • (2006) Curr Opin Lipidol , vol.17 , pp. 387-393
    • Harris, W.S.1    Bulchandani, D.2
  • 24
    • 0025778287 scopus 로고
    • Effects of atherogenic diet consumption on lipoproteins in mouse strains C57BL/6 and C3H
    • Ishida BY, Blanche PJ, Nichols AV, Yasher M, Paigen B (1991) Effects of atherogenic diet consumption on lipoproteins in mouse strains C57BL/6 and C3H. J Lipid Res 32:559-568
    • (1991) J Lipid Res , vol.32 , pp. 559-568
    • Ishida, B.Y.1    Blanche, P.J.2    Nichols, A.V.3    Yasher, M.4    Paigen, B.5
  • 25
    • 0033957165 scopus 로고    scopus 로고
    • Dietary polyunsaturated fatty acids and inflammatory mediator production
    • suppl
    • James MJ, Gibson RA, Cleland LG (2000) Dietary polyunsaturated fatty acids and inflammatory mediator production. Am J Clin Nutr 71(suppl):343S-348S
    • (2000) Am J Clin Nutr , vol.71
    • James, M.J.1    Gibson, R.A.2    Cleland, L.G.3
  • 26
    • 0031213546 scopus 로고    scopus 로고
    • Fish oil-feeding prevents perfluorooctanoic acid-induced fatty liver in mice
    • Kudo N, Kawashima Y (1997) Fish oil-feeding prevents perfluorooctanoic acid-induced fatty liver in mice. Toxicol Appl Pharmacol 145:285-293
    • (1997) Toxicol Appl Pharmacol , vol.145 , pp. 285-293
    • Kudo, N.1    Kawashima, Y.2
  • 28
    • 0027525837 scopus 로고
    • Relative effects of dietary saturated, monounsaturated, and polyunsaturated fatty acids on cardiac arrhythmias in rats
    • McLennan PL (1993) Relative effects of dietary saturated, monounsaturated, and polyunsaturated fatty acids on cardiac arrhythmias in rats. Am J Clin Nutr 57:207-212
    • (1993) Am J Clin Nutr , vol.57 , pp. 207-212
    • McLennan, P.L.1
  • 29
    • 0023762651 scopus 로고
    • Dietary fish oil prevents ventricular fibrillation following coronary artery occlusion and reperfusion
    • McLennan PL, Abeywardena MY, Charnock JS (1988) Dietary fish oil prevents ventricular fibrillation following coronary artery occlusion and reperfusion. Am Heart J 116:709-717
    • (1988) Am Heart J , vol.116 , pp. 709-717
    • McLennan, P.L.1    Abeywardena, M.Y.2    Charnock, J.S.3
  • 30
    • 0027486661 scopus 로고
    • Comparative efficacy of n-3 and n-6 polyunsaturated fatty acids in modulating ventricular fibrillation threshold in marmoset monkeys
    • McLennan PL, Bridle TM, Abeywardena MY, Charnock JS (1993) Comparative efficacy of n-3 and n-6 polyunsaturated fatty acids in modulating ventricular fibrillation threshold in marmoset monkeys. Am J Clin Nutr 58:666-669
    • (1993) Am J Clin Nutr , vol.58 , pp. 666-669
    • McLennan, P.L.1    Bridle, T.M.2    Abeywardena, M.Y.3    Charnock, J.S.4
  • 32
    • 0034016538 scopus 로고    scopus 로고
    • Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL particle size, glucose, and insulin in mildly hyperlipidemic men
    • Mori TA, Burke V, Puddey IB, Watts GF, O'Neal DN, Best JD, Beilin LJ (2000) Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL particle size, glucose, and insulin in mildly hyperlipidemic men. Am J Clin Nutr 71:1085-1094
    • (2000) Am J Clin Nutr , vol.71 , pp. 1085-1094
    • Mori, T.A.1    Burke, V.2    Puddey, I.B.3    Watts, G.F.4    O'Neal, D.N.5    Best, J.D.6    Beilin, L.J.7
  • 33
    • 33745305434 scopus 로고    scopus 로고
    • Fish oil regulates adiponectin secretion by a peroxisome proliferators-activated receptor-gamma-dependent mechanism in mice
    • Neschen S, Morino K, Rossbacher JC, Pongratz RL, Cline GW, Sono S, Gillum M, Shulman GI (2006) Fish oil regulates adiponectin secretion by a peroxisome proliferators-activated receptor-gamma-dependent mechanism in mice. Diabetes 55:924-928
    • (2006) Diabetes , vol.55 , pp. 924-928
    • Neschen, S.1    Morino, K.2    Rossbacher, J.C.3    Pongratz, R.L.4    Cline, G.W.5    Sono, S.6    Gillum, M.7    Shulman, G.I.8
  • 34
    • 11844274574 scopus 로고    scopus 로고
    • Dietary fish oil dose- and time-response effects on cardiac phospholipid fatty acid composition
    • Owen AJ, Peter-Przyborowska BA, Hoy AJ, McLennan PL (2004) Dietary fish oil dose- and time-response effects on cardiac phospholipid fatty acid composition. Lipids 39:955-961
    • (2004) Lipids , vol.39 , pp. 955-961
    • Owen, A.J.1    Peter-Przyborowska, B.A.2    Hoy, A.J.3    McLennan, P.L.4
  • 36
    • 0036776120 scopus 로고    scopus 로고
    • The importance of the ratio of omega-6/omega-3 essential fatty acids
    • Simopoulos AP (2002) The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomed Pharmacother 56:365-379
    • (2002) Biomed Pharmacother , vol.56 , pp. 365-379
    • Simopoulos, A.P.1
  • 37
    • 0032819001 scopus 로고    scopus 로고
    • Essential fatty acids in health and chronic disease
    • suppl
    • Simopoulos AP (1999) Essential fatty acids in health and chronic disease. Am J Clin Nutr 70(suppl):560S-569S
    • (1999) Am J Clin Nutr , vol.70
    • Simopoulos, A.P.1
  • 38
    • 0028041558 scopus 로고
    • Dietary fat alters membrane composition in rod outer segments in normal and diabetic rats: Impact on content of very-long-chain (C ≥ 24) polyenoic fatty acids
    • Suh M, Wierzbicki AA, Clandinin MT (1994) Dietary fat alters membrane composition in rod outer segments in normal and diabetic rats: impact on content of very-long-chain (C ≥ 24) polyenoic fatty acids. Biochim Biophys Acta 1214:54-62
    • (1994) Biochim Biophys Acta , vol.1214 , pp. 54-62
    • Suh, M.1    Wierzbicki, A.A.2    Clandinin, M.T.3
  • 39
    • 43949141817 scopus 로고    scopus 로고
    • The impact of different ratios of omega-6 polyunsaturated fatty acids to eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) on atherosclerotic lesion formation and inflammatory factors in the LDL receptor knockout (LDLr-/-) mouse
    • Wang S, Wu D, Matthan N, Lichtenstein A (2007) The impact of different ratios of omega-6 polyunsaturated fatty acids to eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) on atherosclerotic lesion formation and inflammatory factors in the LDL receptor knockout (LDLr-/-) mouse. FASEB J 21:231.1
    • (2007) FASEB J , vol.21 , pp. 2311
    • Wang, S.1    Wu, D.2    Matthan, N.3    Lichtenstein, A.4
  • 40
    • 33847103105 scopus 로고    scopus 로고
    • Fish oil significantly alters fatty acid profiles in various lipid fractions but not atherogenesis in apo E-KO mice
    • (Epub ahead of print)
    • Xu Z, Riediger N, Innis S, Moghadasian MH (2007) Fish oil significantly alters fatty acid profiles in various lipid fractions but not atherogenesis in apo E-KO mice. Eur J Nutr (Epub ahead of print)
    • (2007) Eur J Nutr
    • Xu, Z.1    Riediger, N.2    Innis, S.3    Moghadasian, M.H.4
  • 41
    • 23944476652 scopus 로고    scopus 로고
    • Varying the ratio of dietary n-6:n-3 polyunsaturated fatty acid alters the tendency to thrombosis and progress of atherosclerosis in apoE-/- LDLR-/- double knockout mouse
    • Yamashita T, Oda E, Sano T, Yamashita T, Ijiru Y, Giddings JC, Yamamoto J (2005) Varying the ratio of dietary n-6:n-3 polyunsaturated fatty acid alters the tendency to thrombosis and progress of atherosclerosis in apoE-/- LDLR-/- double knockout mouse. Thromb Res 116:393-401
    • (2005) Thromb Res , vol.116 , pp. 393-401
    • Yamashita, T.1    Oda, E.2    Sano, T.3    Yamashita, T.4    Ijiru, Y.5    Giddings, J.C.6    Yamamoto, J.7
  • 42
    • 37749013583 scopus 로고    scopus 로고
    • Fish oil prevents sucrose-induced fatty liver but exacerbates high-safflower oil-induced fatty liver in ddy mice
    • Yamazaki T, Nakamori A, Sasaki E, Wada S, Ezaki O (2007) Fish oil prevents sucrose-induced fatty liver but exacerbates high-safflower oil-induced fatty liver in ddy mice. Hepatology 46:1779-1790
    • (2007) Hepatology , vol.46 , pp. 1779-1790
    • Yamazaki, T.1    Nakamori, A.2    Sasaki, E.3    Wada, S.4    Ezaki, O.5
  • 43
    • 7944228499 scopus 로고    scopus 로고
    • Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women
    • Zhao G, Etherton TD, Martin KR, West SG, Gillies PJ, Kris-Etherton PM (2004) Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women. J Nutr 134:2991-2997
    • (2004) J Nutr , vol.134 , pp. 2991-2997
    • Zhao, G.1    Etherton, T.D.2    Martin, K.R.3    West, S.G.4    Gillies, P.J.5    Kris-Etherton, P.M.6


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