Review article: Medication non-adherence in ulcerative colitis - Strategies to improve adherence with mesalazine and other maintenance therapies

Alimentary Pharmacology and Therapeutics

Volumn 27, Issue 12, 2008, Pages 1157-1166

  Hawthorne, A B ^a   Rubin, G ^a   Ghosh, S ^a  

^a UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; ENEMA; IMMUNOSUPPRESSIVE AGENT; MESALAZINE; STEROID;

AGE; BEHAVIOR MODIFICATION; DEPRESSION; DISEASE DURATION; DISEASE SEVERITY; DOCTOR PATIENT RELATION; EMPLOYMENT STATUS; HEALTH BELIEF; HEALTH CARE COST; HUMAN; MAINTENANCE THERAPY; MARRIAGE; MEDLINE; PATIENT COMPLIANCE; PATIENT EDUCATION; PRIORITY JOURNAL; QUALITY OF LIFE; RELAPSE; REMISSION; REVIEW; RISK FACTOR; SELF CARE; SEX ROLE; ULCERATIVE COLITIS; UNITED KINGDOM;

ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; COLITIS, ULCERATIVE; FEMALE; GREAT BRITAIN; HEALTH CARE COSTS; HUMANS; INFLAMMATORY BOWEL DISEASES; MALE; MESALAMINE; PATIENT EDUCATION AS TOPIC; PHYSICIAN-PATIENT RELATIONS; PREDICTIVE VALUE OF TESTS; RECURRENCE; TREATMENT REFUSAL;

EID: 43849111351     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2008.03698.x     Document Type: Review

References (60)

1. Sutherland L, Macdonald JK. Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis. Cochrane Database Syst Rev 2006 2 : 1 16.
2. Sutherland L, Macdonald JK. Oral 5-aminosalicylic acid for maintenance of remission in ulcerative colitis. Cochrane Database Syst Rev 2006 2 : 1 25.
3. Eaden J, Abrams K, Ekbom A, et al. Colorectal cancer prevention in ulcerative colitis: a case-control study. Aliment Pharmacol Ther 2000 14 : 145 53.
4. Velayos FS, Terdiman JP, Walsh JM. Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: a systematic review and meta-analysis of observational studies. Am J Gastroenterol 2005 100 : 1345 53.
5. Vaur L, Vaisse B, Genes N, et al. Use of electronic pill boxes to assess risk of poor treatment compliance: results of a large-scale trial. Am J Hypertens 1999 12 : 374 80.
6. Caro JJ, Salas M, Speckman JL, et al. Persistence with treatment for hypertension in actual practice. CMAJ 1999 160 : 64 5.
7. Evans JM, Newton RW, Ruta DA, et al. Frequency of blood glucose monitoring in relation to glycaemic control: observational study with diabetes database. BMJ 1999 319 : 83 6.
8. Kane SV, Cohen RD, Aikens JE, Hanauer SB. Prevalence of non-adherence with maintenance mesalamine in quiescent ulcerative colitis. Am J Gastroenterol 2001 96 : 2929 33.
9. Sninsky CA, Cort DH, Shanahan F, et al. Oral mesalamine (Asacol) for mildly to moderately active ulcerative colitis. A multicenter study. Ann Intern Med 1991 115 : 350 5.
10. Kane SV. Systematic review: adherence issues in the treatment of ulcerative colitis. Aliment Pharmacol Ther 2006 23 : 577 85.
11. Rubin G, Hungin AP, Chinn D, et al. Long-term aminosalicylate therapy is under-used in patients with ulcerative colitis: a cross-sectional survey. Aliment Pharmacol Ther 2002 16 : 1889 93.
12. Bernal I, Domènech E, Garcia-Planella E, et al. Medication-taking behaviour in a cohort of patients with inflammatory bowel disease. Dig Dis Sci 2006 51 : 2165 9.
13. López-San Román, Bermejo F, Carrera E, et al. Adherence to treatment in inflammatory bowel disease. Rev Esp Enferm Dig 2005 97 : 249 57.
14. Shale MJ, Riley SA. Studies of compliance with delayed-release mesalazine therapy in patients with inflammatory bowel disease. Aliment Pharmacol Ther 2003 18 : 191 8.
15. Beardon PH, McGilchrist MM, McKendrick AD, et al. Primary non-compliance with prescribed medication in primary care. BMJ 1993 307 : 846 8.
16. Robinson A. Patient-reported compliance with 5-ASA drugs in inflammatory bowel disease: a multi-national study. Gastroenterology 2002 122 : A-499.
17. Shaw IS, Jobson BA, Silverman D. Is your patient taking the medicine? A simple assay to measure compliance with 5-aminosalicylic acid-containing compounds. Aliment Pharmacol Ther 2002 16 : 2053 9.
18. Kane S, Huo D, Aikens J, et al. Medication non-adherence and outcomes of patients with quiescent ulcerative colitis. Am J Med 2003 114 : 39 43.
19. Hjortswang H, Jarnerot G, Curman B, et al. The influence of demographic and disease-related factors on health-related quality of life in patients with ulcerative colitis. Eur J Gastroenterol Hepatol 2003 15 : 1011 20.
20. Brentnall TA. Molecular underpinnings of cancer in ulcerative colitis. Curr Opin Gastroenterol 2003 19 : 64 8.
21. Van Staa TP, Card T, Logan RF, et al. Aminosalicylate use and colorectal cancer risk in inflammatory bowel disease: a large epidemiological study. Gut 2005 54 : 1573 8.
22. Moody GA, Jayanthi V, Probert CS, et al. Long-term therapy with sulphasalazine protects against colorectal cancer in ulcerative colitis: a retrospective study of colorectal cancer risk and compliance with treatment in Leicestershire. Eur J Gastroenterol Hepatol 1996 8 : 1179 83.
23. Bassi A, Dodd S, Williamson P, et al. Cost of illness of inflammatory bowel disease in the UK: a single centre retrospective study. Gut 2004 53 : 1471 8.
24. García Rodríguez LA, González-Pérez A, Johansson S, et al. Risk factors for inflammatory bowel disease in the general population. Aliment Pharmacol Ther 2005 22 : 309 15.
25. Hobden A. Strategies to promote concordance within consultations. Br J Community Nurs 2006 11 : 286 9.
26. Levy RL, Feld AD. Increasing patient adherence to gastroenterology treatment and prevention regimens. Am J Gastroenterol 1999 94 : 1733 42.
27. Sewitch MA, Abrahamowicz M, Barkun A, et al. Patient non-adherence to medication in inflammatory bowel disease. Am J Gastroenterol 2003 98 : 1535 44.
28. D'Inca R, Bertomoro P, Mazzocco K, et al. Risk factors for non-adherence to medication in inflammatory bowel disease patients. Aliment Pharmacol Ther 2008 27 : 166 72.
29. Cervený P, Bortlík M, Kubena A, et al. Nonadherence in inflammatory bowel disease: results of factor analysis. Inflamm Bowel Dis 2007 13 : 1244 9.
30. Schneider J, Kaplan SH, Greenfield S, et al. Better physician-patient relationships are associated with higher reported adherence to antiviral therapy in patients with HIV infection. J Gen Intern Med 2004 19 : 1096 103.
31. Beach MC, Keruly J, Moore RD. Is the quality of the patient-provider relationship associated with better adherence and health outcomes for patients with HIV. J Gen Intern Med 2006 21 : 661 5.
32. Wroth TH, Pathman DE. Primary medication adherence in a rural population: the role of the patient-physician relationship and satisfaction with care. J Am Board Fam Med 2006 19 : 478 86.
33. Bass MJ, Buck C, Turner L, et al. The physician's actions and the outcome of illness in family practice. J Fam Pract 1986 23 : 43 7.
34. Rost K, Carter W, Inui T. Introduction of information during the initial medical visit: consequences for patient follow-through with physician recommendations for medication. Soc Sci Med 1989 28 : 315 21.
35. Kerse N, Buetow S, Mainous AG, et al. Physician-patient relationship and medication compliance: a primary care investigation. Ann Fam Med 2004 2 : 455 61.
36. Drossman DA. Psychosocial sound bites: exercises in the patient-physician relationship. Am J Gastroenterol 1997 92 : 1418 23.
37. Cecil WD, Killeen J. Control, compliance, and satisfaction in the family practice encounter. Fam Med 1997 29 : 653 7.
38. Donovan JL, Blake DR. Patient non-compliance: deviance or reasoned decision-making. Soc Sci Med 1992 34 : 507 13.
39. Veazie PJ, Cai S. A connection between medication adherence, patient sense of uniqueness, and the personalization of information. Med Hypotheses 2007 68 : 335 42.
40. Horne R, Weinman J. Patients' beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. J Psychosom Res 1999 47 : 555 67.
41. Hall NJ, Rubin GP, Dougall A, et al. The fight for 'health-related normality': a qualitative study of the experiences of individuals living with established inflammatory bowel disease (IBD). J Health Psychol 2005 10 : 443 55.
42. Hall NJ, Rubin GP, Hungin AP, Dougall A. Medication beliefs among patients with inflammatory bowel disease who report low quality of life: a qualitative study. BMC Gastroenterol 2007 7 : 20.
43. Stockwell Morris L, Schulz RM. Patient compliance - an overview. J Clin Pharm Ther 1992 17 : 283 95.
44. Kripalani S, Yao X, Haynes B. Interventions to enhance medication adherence in chronic medical conditions: a systematic review. Arch Intern Med 2007 167 : 540 9.
45. Abbott SA. The benefits of patient education. Gastroenterol Nurs 1998 21 : 207 9.
46. Rowlinson A. Inflammatory bowel disease 3: importance of partnership in care. Br J Nurs 1999 8 : 1013 8.
47. Krueger KP, Felkey BG, Berger BA. Improving adherence and persistence: a review and assessment of interventions and description of steps toward a national adherence initiative. Am J Pharm Assoc (Wash) 2003 43 : 668 78.
48. Robinson GL, Gilbertson AD, Litwack L. The effects of a psychiatric patient education to medication program on post discharge compliance. Psychiatric Q 1987 58 : 113 8.
49. Waters BM, Jensen L, Fedorak R. Effects of formal education for patients with inflammatory bowel disease: a randomized controlled trial. Can J Gastroenterol 2005 19 : 235 44.
50. Robinson A, Thompson DG, Wilkin D, et al. Guided self-management and patient-directed follow-up of ulcerative colitis: a randomised trial. Lancet 2001 358 : 976 81.
51. Kennedy AP, Nelson E, Reeves D, et al. A randomised controlled trial to assess the effectiveness and cost pf a patient orientated self management approach to chronic inflammatory bowel disease. Gut 2004 53 : 1639 45.
52. Richardson G, Sculpher M, Kennedy A, et al. Is self-care a cost effective use of resources? Evidence from a randomised trial in inflammatory bowel disease J Health Serv Res Policy 2006 11 : 225 30.
53. Robinson A. Review article: inflammatory bowel disease - empowering the patient and improving outcomes. Aliment Pharmacol Ther 2004 20 (Suppl. 4 84 7.
54. Epstein LH, Cluss PA. A behavioural medicine perspective on adherence to long-term medical regimens. J Consult Clin Psychol 1982 50 : 950 71.
55. Claxton AJ, Cramer J, Pierce C. A systematic review of the associations between dose regimens and medication compliance. Clin Ther 2001 23 : 1296 310.
56. Eisen SA, Miller DK, Woodward RS, et al. The effect of prescribed daily dose frequency on patient medication compliance. Arch Int Med 1990 150 : 1881 4.
57. Greenberg RN. Overview of patient compliance with medication dosing: a literature review. Clin Ther 1984 6 : 592 9.
58. Dignass A, Veerman H. Once versus twice daily mesalazine (Pentasa) granules for the maintenance of remission in ulcerative colitis: results from a multinational randomised controlled trial. Gut 2008 57 (Suppl. 1 A1.
59. Petrilla AA, Benner JS, Battleman DS, et al. Evidence-based interventions to improve patient compliance with antihypertensive and lipid-lowering medications. Int J Clin Pract 2005 59 : 1441 51.
60. Simkins CV, Wenzloff NJ. Evaluation of a computerised reminder system in the enhancement of patient medication refill compliance. Drug Intell Clin Pharm 1986 20 : 799 802.