Enantioselectivity in the synthesis of 3,5-disubstituted Δ2-isoxazolines

Tetrahedron Letters

Volumn 49, Issue 26, 2008, Pages 4153-4155

  Norman, Amber L ^a   Mosher, Michael D ^a  

^a UNIVERSITY OF NEBRASKA AT KEARNEY   (United States)

Author keywords

Cyclization; Heterocycle synthesis; Isoxazoline; Stereospecific reactions

Indexed keywords

ISOXAZOLINE DERIVATIVE; MACROPHAGE MIGRATION INHIBITION FACTOR; OXIME DERIVATIVE; PALLADIUM;

ARTICLE; CHIRALITY; CYCLIZATION; DRUG SYNTHESIS; ENANTIOSELECTIVITY; INSULIN DEPENDENT DIABETES MELLITUS;

EID: 43849108598     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2008.04.125     Document Type: Article

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13. 1H NMR spectra were obtained and radial chromatography (silica, hexane-ethyl acetate gradient) was used to isolate the isoxazoline for determination of optical purity.