메뉴 건너뛰기




Volumn 27, Issue 12, 2008, Pages 1240-1252

Evaluating anti-viral drug selection and treatment duration in HBeAg-negative chronic hepatitis B: A cost-effectiveness analysis

Author keywords

[No Author keywords available]

Indexed keywords

ADEFOVIR; ENTECAVIR; HEPATITIS B(E) ANTIGEN; LAMIVUDINE;

EID: 43849091109     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2008.03691.x     Document Type: Article
Times cited : (31)

References (56)
  • 3
    • 1542316127 scopus 로고    scopus 로고
    • Hepatitis B virus infection - Natural history and clinical consequences
    • Ganem D, Prince AM. Hepatitis B virus infection - natural history and clinical consequences. N Engl J Med 2004 350 : 1118 29.
    • (2004) N Engl J Med , vol.350 , pp. 1118-29
    • Ganem, D.1    Prince, A.M.2
  • 4
    • 0041859593 scopus 로고    scopus 로고
    • Prevalence of HBV precore/core promoter variants in the United States
    • Chu CJ, Keeffe EB, Han SH, et al. Prevalence of HBV precore/core promoter variants in the United States. Hepatology 2003 38 : 619 28.
    • (2003) Hepatology , vol.38 , pp. 619-28
    • Chu, C.J.1    Keeffe, E.B.2    Han, S.H.3
  • 5
    • 33750978162 scopus 로고    scopus 로고
    • Chronic hepatitis B: Current epidemiology in the Americas and implications for management
    • Gish RG, Gadano AC. Chronic hepatitis B: current epidemiology in the Americas and implications for management. J Viral Hepat 2006 13 : 787 98.
    • (2006) J Viral Hepat , vol.13 , pp. 787-98
    • Gish, R.G.1    Gadano, A.C.2
  • 6
    • 34248545087 scopus 로고    scopus 로고
    • Characteristics of persons with Chronic Hepatitis B - San Francisco, California, 2006
    • Huang S, Shallow S, Stier D, et al. Characteristics of persons with Chronic Hepatitis B - San Francisco, California, 2006. MMWR Morb Mortal Wkly Rep 2007 56 : 446 8.
    • (2007) MMWR Morb Mortal Wkly Rep , vol.56 , pp. 446-8
    • Huang, S.1    Shallow, S.2    Stier, D.3
  • 8
    • 33644858331 scopus 로고    scopus 로고
    • Predicting cirrhosis risk based on the level of circulating hepatitis B viral load
    • Iloeje UH, Yang HI, Su J, Jen CL, You SL, Chen CJ. Predicting cirrhosis risk based on the level of circulating hepatitis B viral load. Gastroenterology 2006 130 : 678 86.
    • (2006) Gastroenterology , vol.130 , pp. 678-86
    • Iloeje, U.H.1    Yang, H.I.2    Su, J.3    Jen, C.L.4    You, S.L.5    Chen, C.J.6
  • 9
    • 0022641584 scopus 로고
    • Early detection of hepatocellular carcinoma in patients with chronic type B hepatitis. a prospective study
    • Liaw YF, Tai DI, Chu CM, et al. Early detection of hepatocellular carcinoma in patients with chronic type B hepatitis. A prospective study. Gastroenterology 1986 90 : 263 7.
    • (1986) Gastroenterology , vol.90 , pp. 263-7
    • Liaw, Y.F.1    Tai, D.I.2    Chu, C.M.3
  • 10
    • 29944436855 scopus 로고    scopus 로고
    • Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level
    • Chen CJ, Yang HI, Su J, et al. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA 2006 295 : 65 73.
    • (2006) JAMA , vol.295 , pp. 65-73
    • Chen, C.J.1    Yang, H.I.2    Su, J.3
  • 11
    • 32044452719 scopus 로고    scopus 로고
    • Chronic hepatitis B: A critical appraisal of current approaches to therapy
    • Perrillo RP, Gish RG, Peters M, et al. Chronic hepatitis B: a critical appraisal of current approaches to therapy. Clin Gastroenterol Hepatol 2006 4 : 233 48.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 233-48
    • Perrillo, R.P.1    Gish, R.G.2    Peters, M.3
  • 12
    • 0038276960 scopus 로고    scopus 로고
    • Serum HBV DNA as a marker of efficacy during therapy for chronic HBV infection: Analysis and review of the literature
    • Mommeja-Marin H, Mondou E, Blum MR, Rousseau F. Serum HBV DNA as a marker of efficacy during therapy for chronic HBV infection: analysis and review of the literature. Hepatology 2003 37 : 1309 19.
    • (2003) Hepatology , vol.37 , pp. 1309-19
    • Mommeja-Marin, H.1    Mondou, E.2    Blum, M.R.3    Rousseau, F.4
  • 13
    • 21244504689 scopus 로고    scopus 로고
    • The maze of treatments for hepatitis B
    • Lok AS. The maze of treatments for hepatitis B. N Engl J Med 2005 352 : 2743 6.
    • (2005) N Engl J Med , vol.352 , pp. 2743-6
    • Lok, A.S.1
  • 14
    • 33847701354 scopus 로고    scopus 로고
    • AASLD Practice Guidelines: Chronic Hepatitis B
    • Lok A, McMahon B. AASLD Practice Guidelines: Chronic Hepatitis B. Hepatology 2007 45 : 507 39.
    • (2007) Hepatology , vol.45 , pp. 507-39
    • Lok, A.1    McMahon, B.2
  • 15
    • 35549005997 scopus 로고    scopus 로고
    • Cost Effectiveness of Entecavir vs. Lamivudine with Adefovir Salvage in HBeAg-Positive Chronic Hepatitis B
    • Veenstra DL, Sullivan SD, Clarke L, et al. Cost Effectiveness of Entecavir vs. Lamivudine with Adefovir Salvage in HBeAg-Positive Chronic Hepatitis B. Pharmacoeconomics 2007 25 : 963 77.
    • (2007) Pharmacoeconomics , vol.25 , pp. 963-77
    • Veenstra, D.L.1    Sullivan, S.D.2    Clarke, L.3
  • 16
    • 0002013325 scopus 로고    scopus 로고
    • Time Preference
    • In: Gold, M.R., Siegel, J.E., Russell, L.B., Weinstein, M.C., eds. New York: Oxford University Press
    • Lipscomb J, Weinstein MC, Torrance GW. Time Preference. In : Gold MR, Siegel JE, Russell LB, Weinstein MC, eds. Cost-effectiveness in Health and Medicine. New York : Oxford University Press, 1996 : 214 46.
    • (1996) Cost-effectiveness in Health and Medicine. , pp. 214-46
    • Lipscomb, J.1    Weinstein, M.C.2    Torrance, G.W.3
  • 17
    • 33644822860 scopus 로고    scopus 로고
    • Entecavir vs. Lamivudine for Patients with HBeAg-Negative Chronic Hepatitis B
    • Lai C-L, Shouval D, Lok AS, et al. Entecavir vs. Lamivudine for Patients with HBeAg-Negative Chronic Hepatitis B. N Engl J Med 2006 354 : 1011 20.
    • (2006) N Engl J Med , vol.354 , pp. 1011-20
    • Lai, C.-L.1    Shouval, D.2    Lok, A.S.3
  • 18
    • 0037468406 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B. N Engl J Med 2003 348 : 800 7.
    • (2003) N Engl J Med , vol.348 , pp. 800-7
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 19
    • 21244455293 scopus 로고    scopus 로고
    • Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B. N Engl J Med 2005 352 : 2673 81.
    • (2005) N Engl J Med , vol.352 , pp. 2673-81
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 20
    • 0036614299 scopus 로고    scopus 로고
    • Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B
    • Hsu YS, Chien RN, Yeh CT, et al. Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B. Hepatology 2002 35 : 1522 7.
    • (2002) Hepatology , vol.35 , pp. 1522-7
    • Hsu, Y.S.1    Chien, R.N.2    Yeh, C.T.3
  • 21
    • 0036840812 scopus 로고    scopus 로고
    • Effect of hepatitis B and C virus infections on the natural history of compensated cirrhosis: A cohort study of 297 patients
    • Fattovich G, Pantalena M, Zagni I, Realdi G, Schalm SW, Christensen E. Effect of hepatitis B and C virus infections on the natural history of compensated cirrhosis: a cohort study of 297 patients. Am J Gastroenterol 2002 97 : 2886 95.
    • (2002) Am J Gastroenterol , vol.97 , pp. 2886-95
    • Fattovich, G.1    Pantalena, M.2    Zagni, I.3    Realdi, G.4    Schalm, S.W.5    Christensen, E.6
  • 23
    • 33749670275 scopus 로고    scopus 로고
    • Adefovir dipivoxil and pegylated interferon alfa-2a for the treatment of chronic hepatitis B: A systematic review and economic evaluation
    • Shepherd J, Jones J, Takeda A, Davidson P, Price A. Adefovir dipivoxil and pegylated interferon alfa-2a for the treatment of chronic hepatitis B: a systematic review and economic evaluation. Health Technol Assess 2006 10 : iii iv, xi xiv, 1 183.
    • (2006) Health Technol Assess , vol.10
    • Shepherd, J.1    Jones, J.2    Takeda, A.3    Davidson, P.4    Price, A.5
  • 24
    • 18644369134 scopus 로고    scopus 로고
    • Treatment alternatives for chronic hepatitis B virus infection: A cost-effectiveness analysis
    • Kanwal F, Gralnek IM, Martin P, Dulai GS, Farid M, Spiegel BM. Treatment alternatives for chronic hepatitis B virus infection: a cost-effectiveness analysis. Ann Intern Med 2005 142 : 821 31.
    • (2005) Ann Intern Med , vol.142 , pp. 821-31
    • Kanwal, F.1    Gralnek, I.M.2    Martin, P.3    Dulai, G.S.4    Farid, M.5    Spiegel, B.M.6
  • 25
    • 20144380179 scopus 로고    scopus 로고
    • Adefovir dipivoxil added to ongoing lamivudine therapy in patients with lamivudine-resistant hepatitis B e antigen-negative chronic hepatitis B
    • Vassiliadis T, Nikolaidis N, Giouleme O, et al. Adefovir dipivoxil added to ongoing lamivudine therapy in patients with lamivudine-resistant hepatitis B e antigen-negative chronic hepatitis B. Aliment Pharmacol Ther 2005 21 : 531 7.
    • (2005) Aliment Pharmacol Ther , vol.21 , pp. 531-7
    • Vassiliadis, T.1    Nikolaidis, N.2    Giouleme, O.3
  • 26
    • 32444438958 scopus 로고    scopus 로고
    • Adefovir rapidly suppresses hepatitis B in HBeAg-negative patients developing genotypic resistance to lamivudine
    • Lampertico P, Vigano M, Manenti E, Iavarone M, Lunghi G, Colombo M. Adefovir rapidly suppresses hepatitis B in HBeAg-negative patients developing genotypic resistance to lamivudine. Hepatology 2005 42 : 1414 9.
    • (2005) Hepatology , vol.42 , pp. 1414-9
    • Lampertico, P.1    Vigano, M.2    Manenti, E.3    Iavarone, M.4    Lunghi, G.5    Colombo, M.6
  • 27
    • 33847709539 scopus 로고    scopus 로고
    • Adding-on vs. switching-to adefovir therapy in lamivudine-resistant HBeAg-negative chronic hepatitis B
    • Rapti I, Dimou E, Mitsoula P, Hadziyannis SJ. Adding-on vs. switching-to adefovir therapy in lamivudine-resistant HBeAg-negative chronic hepatitis B. Hepatology 2007 45 : 307 13.
    • (2007) Hepatology , vol.45 , pp. 307-13
    • Rapti, I.1    Dimou, E.2    Mitsoula, P.3    Hadziyannis, S.J.4
  • 29
    • 33845671388 scopus 로고    scopus 로고
    • Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years. Gastroenterology 2006 131 : 1743 51.
    • (2006) Gastroenterology , vol.131 , pp. 1743-51
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 30
    • 0037383496 scopus 로고    scopus 로고
    • EASL International Consensus Conference on Hepatitis B. 13-14 September, 2002: Geneva, Switzerland. Consensus statement (short version)
    • EASL.
    • EASL. EASL International Consensus Conference on Hepatitis B. 13-14 September, 2002: Geneva, Switzerland. Consensus statement (short version). J Hepatol 2003 38 : 533 40.
    • (2003) J Hepatol , vol.38 , pp. 533-40
  • 31
    • 0022641368 scopus 로고
    • Chronic hepatitis in HBsAg carriers with serum HBV-DNA and anti-HBe
    • Bonino F, Rosina F, Rizzetto M, et al. Chronic hepatitis in HBsAg carriers with serum HBV-DNA and anti-HBe. Gastroenterology 1986 90 : 1268 73.
    • (1986) Gastroenterology , vol.90 , pp. 1268-73
    • Bonino, F.1    Rosina, F.2    Rizzetto, M.3
  • 32
    • 0026343230 scopus 로고
    • 'e' antigen defective hepatitis B virus and course of chronic infection
    • Brunetto MR, Giarin M, Oliveri F, et al. 'e' antigen defective hepatitis B virus and course of chronic infection. J Hepatol 1991 13 (Suppl 4 S82 6.
    • (1991) J Hepatol , vol.13 , Issue.4
    • Brunetto, M.R.1    Giarin, M.2    Oliveri, F.3
  • 34
    • 0036230712 scopus 로고    scopus 로고
    • Introduction of lamivudine for the treatment of chronic hepatitis B: Expected clinical and economic outcomes based on 4-year clinical trial data
    • Crowley S, Tognarini D, Desmond P, Lees M, Saal G. Introduction of lamivudine for the treatment of chronic hepatitis B: expected clinical and economic outcomes based on 4-year clinical trial data. J Gastroenterol Hepatol 2002 17 : 153 64.
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 153-64
    • Crowley, S.1    Tognarini, D.2    Desmond, P.3    Lees, M.4    Saal, G.5
  • 37
    • 35548982773 scopus 로고    scopus 로고
    • The natural history of chronic hepatitis B infection: A new computer simulation model to incorporate events subsequent to HBeAg seroconversion
    • Chicago, IL, 14-19 May
    • Kim WR, Veenstra DL, Iloeje UH, et al. The natural history of chronic hepatitis B infection: a new computer simulation model to incorporate events subsequent to HBeAg seroconversion. Digestive Disease Week, Chicago, IL, 14-19 May, 2005.
    • (2005) Digestive Disease Week
    • Kim, W.R.1    Veenstra, D.L.2    Iloeje, U.H.3
  • 38
    • 0028918747 scopus 로고
    • Cost-effectiveness of interferon-alpha 2b treatment for hepatitis B e antigen-positive chronic hepatitis B
    • Wong JB, Koff RS, Tine F, Pauker SG. Cost-effectiveness of interferon-alpha 2b treatment for hepatitis B e antigen-positive chronic hepatitis B. Ann Intern Med 1995 122 : 664 75.
    • (1995) Ann Intern Med , vol.122 , pp. 664-75
    • Wong, J.B.1    Koff, R.S.2    Tine, F.3    Pauker, S.G.4
  • 39
    • 0036767840 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of interferon-alpha therapy in the treatment of chronic hepatitis B in Taiwan
    • Pwu RF, Chan KA. Cost-effectiveness analysis of interferon-alpha therapy in the treatment of chronic hepatitis B in Taiwan. J Formos Med Assoc 2002 101 : 632 41.
    • (2002) J Formos Med Assoc , vol.101 , pp. 632-41
    • Pwu, R.F.1    Chan, K.A.2
  • 41
    • 4544239807 scopus 로고    scopus 로고
    • Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B
    • Marcellin P, Lau GK, Bonino F, et al. Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B. N Engl J Med 2004 351 : 1206 17.
    • (2004) N Engl J Med , vol.351 , pp. 1206-17
    • Marcellin, P.1    Lau, G.K.2    Bonino, F.3
  • 42
    • 33846469431 scopus 로고    scopus 로고
    • Assessment at three years shows high barrier to resistance is maintained in entecavir-treated nucleoside naïve patients while resistance emergence increases over time in lamivudine refractory patients
    • Boston, MA
    • Colonno R, Rose R, Pokornowski K, Baldick C, Klesczewski K, Tenney D. Assessment at three years shows high barrier to resistance is maintained in entecavir-treated nucleoside naïve patients while resistance emergence increases over time in lamivudine refractory patients. AASLD Annual Meeting, Boston, MA, 2006.
    • (2006) AASLD Annual Meeting
    • Colonno, R.1    Rose, R.2    Pokornowski, K.3    Baldick, C.4    Klesczewski, K.5    Tenney, D.6
  • 43
    • 33845675367 scopus 로고    scopus 로고
    • Entecavir resistance is rare in nucleoside naive patients with hepatitis B
    • Colonno RJ, Rose R, Baldick CJ, et al. Entecavir resistance is rare in nucleoside naive patients with hepatitis B. Hepatology 2006 44 : 1656 65.
    • (2006) Hepatology , vol.44 , pp. 1656-65
    • Colonno, R.J.1    Rose, R.2    Baldick, C.J.3
  • 44
    • 4644295202 scopus 로고    scopus 로고
    • Clinical outcome of HBeAg-negative chronic hepatitis B in relation to virological response to lamivudine
    • Di Marco V, Marzano A, Lampertico P, et al. Clinical outcome of HBeAg-negative chronic hepatitis B in relation to virological response to lamivudine. Hepatology 2004 40 : 883 91.
    • (2004) Hepatology , vol.40 , pp. 883-91
    • Di Marco, V.1    Marzano, A.2    Lampertico, P.3
  • 45
    • 0038352047 scopus 로고    scopus 로고
    • Cost-effectiveness of treatment for chronic hepatitis C infection in an evolving patient population
    • Salomon JA, Weinstein MC, Hammitt JK, Goldie SJ. Cost-effectiveness of treatment for chronic hepatitis C infection in an evolving patient population. JAMA 2003 290 : 228 37.
    • (2003) JAMA , vol.290 , pp. 228-37
    • Salomon, J.A.1    Weinstein, M.C.2    Hammitt, J.K.3    Goldie, S.J.4
  • 46
    • 0032580121 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • author reply 1312-3.
    • Chen PJ, Chen DS. Hepatitis B virus infection. N Engl J Med 1998 338 : 1312 author reply 1312-3.
    • (1998) N Engl J Med , vol.338 , pp. 1312
    • Chen, P.J.1    Chen, D.S.2
  • 48
    • 68349107701 scopus 로고    scopus 로고
    • The impact of chronic hepatitis B on quality of life: A multinational study of utilities from infected and non-infected persons
    • PMID: 18179664.
    • Levy AR, Kowdley KV, Iloeje U, et al. The impact of chronic hepatitis B on quality of life: a multinational study of utilities from infected and non-infected persons. Value Health 2007 PMID: 18179664.
    • (2007) Value Health
    • Levy, A.R.1    Kowdley, K.V.2    Iloeje, U.3
  • 49
    • 0035669803 scopus 로고    scopus 로고
    • Representing uncertainty: The role of cost-effectiveness acceptability curves
    • Fenwick E, Claxton K, Sculpher M. Representing uncertainty: the role of cost-effectiveness acceptability curves. Health Econ 2001 10 : 779 87.
    • (2001) Health Econ , vol.10 , pp. 779-87
    • Fenwick, E.1    Claxton, K.2    Sculpher, M.3
  • 50
    • 33747115307 scopus 로고    scopus 로고
    • Using and interpreting cost-effectiveness acceptability curves: An example using data from a trial of management strategies for atrial fibrillation
    • Fenwick E, Marshall DA, Levy AR, Nichol G. Using and interpreting cost-effectiveness acceptability curves: an example using data from a trial of management strategies for atrial fibrillation. BMC Health Serv Res 2006 6 : 52.
    • (2006) BMC Health Serv Res , vol.6 , pp. 52
    • Fenwick, E.1    Marshall, D.A.2    Levy, A.R.3    Nichol, G.4
  • 51
    • 33846053592 scopus 로고    scopus 로고
    • Combination therapy for chronic hepatitis B: Simultaneous or sequential?
    • Yuen MF, Lai CL. Combination therapy for chronic hepatitis B: simultaneous or sequential? Am J Gastroenterol 2007 102 : 105 6.
    • (2007) Am J Gastroenterol , vol.102 , pp. 105-6
    • Yuen, M.F.1    Lai, C.L.2
  • 52
    • 0035818616 scopus 로고    scopus 로고
    • Serologic and clinical outcomes of 1536 Alaska Natives chronically infected with hepatitis B virus
    • McMahon BJ, Holck P, Bulkow L, Snowball M. Serologic and clinical outcomes of 1536 Alaska Natives chronically infected with hepatitis B virus. Ann Intern Med 2001 135 : 759 68.
    • (2001) Ann Intern Med , vol.135 , pp. 759-68
    • McMahon, B.J.1    Holck, P.2    Bulkow, L.3    Snowball, M.4
  • 53
    • 0031041924 scopus 로고    scopus 로고
    • Morbidity and mortality in compensated cirrhosis type C: A retrospective follow-up study of 384 patients
    • Fattovich G, Giustina G, Degos F, et al. Morbidity and mortality in compensated cirrhosis type C: a retrospective follow-up study of 384 patients. Gastroenterology 1997 112 : 463 72.
    • (1997) Gastroenterology , vol.112 , pp. 463-72
    • Fattovich, G.1    Giustina, G.2    Degos, F.3
  • 54
    • 0035128185 scopus 로고    scopus 로고
    • Surveillance programme of cirrhotic patients for early diagnosis and treatment of hepatocellular carcinoma: A cost effectiveness analysis
    • Bolondi L, Sofia S, Siringo S, et al. Surveillance programme of cirrhotic patients for early diagnosis and treatment of hepatocellular carcinoma: a cost effectiveness analysis. Gut 2001 48 : 251 9.
    • (2001) Gut , vol.48 , pp. 251-9
    • Bolondi, L.1    Sofia, S.2    Siringo, S.3
  • 55
    • 10744225554 scopus 로고    scopus 로고
    • Long-term safety of lamivudine treatment in patients with chronic hepatitis B
    • Lok AS, Lai CL, Leung N, et al. Long-term safety of lamivudine treatment in patients with chronic hepatitis B. Gastroenterology 2003 125 : 1714 22.
    • (2003) Gastroenterology , vol.125 , pp. 1714-22
    • Lok, A.S.1    Lai, C.L.2    Leung, N.3
  • 56
    • 0029890254 scopus 로고    scopus 로고
    • Chronic viral hepatitis - Benefits of current therapies
    • Hoofnagle JH, Lau D. Chronic viral hepatitis - benefits of current therapies. N Engl J Med 1996 334 : 1470 1.
    • (1996) N Engl J Med , vol.334 , pp. 1470-1
    • Hoofnagle, J.H.1    Lau, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.