Some molecular descriptors for non-specific chromosomal genotoxicity based on hydrophobic interactions

Archives of Toxicology

Volumn 82, Issue 5, 2008, Pages 333-338

  Dorn, Susanne B ^a   Degen, Gisela H ^a   Bolt, Hermann M ^a   Van Der Louw, Jaap ^b   Van Acker, Frederique A A ^b   Den Dobbelsteen, Diels J ^b   Lommerse, Jos P M ^b  

^a LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

^b Organon ^*  (Netherlands)

Author keywords

Aneuploidy; Genotoxicity; Micronucleus; Molecular descriptors; Non specific genotoxicity; QSAR; V79 cells

Indexed keywords

STEROID;

ANEUPLOIDY; ANIMAL CELL; ARTICLE; CELL STRAIN V 79; CHROMOSOME; CONTROLLED STUDY; GENE FUNCTION; GENOTOXICITY; HYDROGEN BOND; HYDROPHOBICITY; MATHEMATICAL COMPUTING; MICRONUCLEUS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL LINE; CHROMOSOMES, MAMMALIAN; CRICETINAE; CRICETULUS; HYDROPHOBICITY; MICRONUCLEUS TESTS; MODELS, CHEMICAL; MOLECULAR STRUCTURE; MUTAGENS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

CRICETULUS GRISEUS;

EID: 43749116510     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-007-0256-8     Document Type: Article

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