The processing of emotional prosody and semantics in schizophrenia: Relationship to gender and IQ

Psychological Medicine

Volumn 38, Issue 6, 2008, Pages 887-898

  Scholten, M R M ^a,c   Aleman, A ^b   Kahn, R S ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Affective prosody; Emotional language; Emotional semantics; Schizophrenia; Sex differences; Visuospatial processing

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EMOTION; FEMALE; GENDER; HUMAN; INTELLIGENCE QUOTIENT; LANGUAGE; MALE; NETHERLANDS; NEUROPSYCHIATRY; SCHIZOPHRENIA; SEMANTICS; TASK PERFORMANCE;

ADULT; ATTENTION; DISCRIMINATION LEARNING; EMOTIONS; FEMALE; HUMANS; INTELLIGENCE; MALE; ORIENTATION; PATTERN RECOGNITION, VISUAL; REACTION TIME; SCHIZOPHRENIA, DISORGANIZED; SCHIZOPHRENIA, PARANOID; SEMANTICS; SEX FACTORS; SPEECH ACOUSTICS; SPEECH PERCEPTION;

EID: 43649109036     PISSN: 00332917     EISSN: 14698978     Source Type: Journal    
DOI: 10.1017/S0033291707001742     Document Type: Article

References (94)

1. Aleman A, Kahn RS (2005). Strange feelings: do amygdala abnormalities dysregulate the emotional brain in schizophrenia? Progress in Neurobiology 77, 283-298.
2. Aleman A, Kahn RS, Selten J-P (2003). Sex differences in the risk of schizophrenia: evidence from meta-analysis. Archives of General Psychiatry 60, 565-571.
3. Allen LS, Richey MF, Chai YM, Gorski RA (1991). Sex differences in the corpus callosum of the living human being. Journal of Neuroscience 11, 933-942.
4. Andreasen NC, Flaum M, Arndt S (1992). The Comprehensive Assessment of Symptoms and History (CASH). An instrument for assessing diagnosis and psychopathology. Archives of General Psychiatry 49, 615-623.
5. Barch DM, Carter CS, Cohen JD (2004). Factors influencing Stroop performance in schizophrenia. Neuropsychology 18, 477-484.
6. Barch DM, Carter CS, Hachten PC, Usher M, Cohen JD (1999). The 'benefits' of distractibility: mechanisms underlying increased Stroop effects in schizophrenia. Schizophrenia Bulletin 25, 749-762.
7. Baxter LC, Saykin AJ, Flashman LA, Johnson SC, Guerin SJ, Babcock DR, Wishart HA (2003). Sex differences in semantic language processing: a functional MRI study. Brain and Language 84, 264-272.
8. Bell EC, Willson MC, Wilman AH, Dave S, Silverstone PH (2006). Males and females differ in brain activation during cognitive tasks. Neuroimage 30, 529-538.
9. Bergemann N, Mundt C, Parzer P, Jannakos I, Nagl I, Salbach B, Klinga K, Runnebaum B, Resch F (2005). Plasma concentrations of estradiol in women suffering from schizophrenia treated with conventional versus atypical antipsychotics. Schizophrenia Research 73, 357-366.
10. Besson M, Magne C, Schon D (2002). Emotional prosody: sex differences in sensitivity to speech melody. Trends in Cognitive Science 6, 405-407.
11. Borod JC, Martin CC, Alpert M, Brozgold A, Welkowitz J (1993). Perception of facial emotion in schizophrenic and right brain-damaged patients. Journal of Nervous and Mental Disease 181, 494-502.
12. Bozikas VP, Kosmidis MH, Anezoulaki D, Giannakou M, Andreou C, Karavatos A (2006). Impaired perception of affective prosody in schizophrenia. Journal of Neuropsychiatry and Clinical Neurosciences 18, 81-85.
13. Buchanan RW, Holstein C, Breier A (1994). The comparative efficacy and long-term effect of clozapine treatment on neuropsychological test performance. Biological Psychiatry 36, 717-725.
14. Buchanan TW, Lutz K, Mirzazade S, Specht K, Shah NJ, Zilles K, Jancke L (2000). Recognition of emotional prosody and verbal components of spoken language: an fMRI study. Brain Research. Cognitive Brain Research 9, 227-238.
15. Burton LA, Henninger D, Hafetz J (2005). Gender differences in relations of mental rotation, verbal fluency, and SAT scores to finger length ratios as hormonal indexes. Developmental Neuropsychology 1, 493-505.
16. Collaer ML, Hines M (1995). Human behavioral sex differences: a role for gonadal hormones during early development? Psychological Bulletin 118, 55-107.
17. Condray R, Steinhauer SR, van Kammen DP, Kasparek A (2002). The language system in schizophrenia: effects of capacity and linguistic structure. Schizophrenia Bulletin 28, 475-490.
18. Corrigan PW, Hirschbeck JN, Wolfe M (1995). Memory and vigilance training to improve social perception in schizophrenia. Schizophrenia Research 17, 257-265.
19. Cutting J (1992). The role of right hemisphere dysfunction in psychiatric disorders. British Journal of Psychiatry 160, 583-588.
20. de Vignemont F, Zalla T, Posada A, Louvegnez A, Koenig O, Georgieff N, Franck N (2006). Mental rotation in schizophrenia. Conscious Cognition 15, 295-309.
21. Diamond MC (1989). Sex and the cerebral cortex. Biological Psychiatry 25, 823-825.
22. Driscoll I, Hamilton DA, Yeo RA, Brooks WM, Sutherland RJ (2005). Virtual navigation in humans: the impact of age, sex, and hormones on place learning. Hormones and Behavior 47, 326-335.
23. Dubb A, Gur R, Avants B, Gee J (2003). Characterization of sexual dimorphism in the human corpus callosum. Neuroimage 20, 512-519.
24. Edwards J, Jackson HJ, Pattison PE (2002). Emotion recognition via facial expression and affective prosody in schizophrenia: a methodological review. Clinical Psychology Review 22, 789-832. Erratum in: Clinical Psychology Review (2002) 22, 1267-1285.
25. Edwards J, Pattison PE, Jackson HJ, Wales RJ (2001). Facial affect and affective prosody recognition in first-episode schizophrenia. Schizophrenia Research 48, 235-253.
26. Epting LK, Overman WH (1998). Sex-sensitive tasks in men and women: a search for performance fluctuations across the menstrual cycle. Behavioral Neuroscience 112, 1304-1317.
27. Frederikse M, Lu A, Aylward E, Barta P, Sharma T, Pearlson G (2000). Sex differences in inferior parietal lobule volume in schizophrenia. American Journal of Psychiatry 157, 422-427.
28. Frederikse ME, Lu A, Aylward E, Barta P, Pearlson G (1999). Sex differences in the inferior parietal lobule. Cerebral Cortex 9, 896-901.
29. Fricchione G, Sedler MJ, Shukla S (1986). Aprosodia in eight schizophrenic patients. American Journal of Psychiatry 143, 1457-1459.
30. Gandour J, Tong Y, Wong D, Talavage T, Dzemidzic M, Xu Y, Li X, Lowe M (2004). Hemispheric roles in the perception of speech prosody. Neuroimage 23, 344-357.
31. Geschwind N, Galaburda AM (1987). Cerebral Lateralization: Biological Mechanisms, Associations and Pathology. MIT Press: Cambridge, MA.
32. Goldstein JM, Cohen LS, Horton NJ, Lee H, Andersen S, Tohen M, Crawford A, Tollefson G (2002b). Sex differences in clinical response to olanzapine compared with haloperidol. Psychiatry Research 110, 27-37.
33. Goldstein JM, Lewine RRJ (2000). Overview of sex differences in schizophrenia: where have we been and where do we go from here? In Women and Schizophrenia (ed. D. J. Castle, J. J. McGrath and J. Kulkarni), pp. 111-153. Cambridge University Press: Cambridge, MA.
34. Goldstein JM, Seidman LJ, O'Brien LM, Horton NJ, Kennedy DN, Makris N, Caviness VS, Faraone SV, Tsuang MT (2002a). Impact of normal sexual dimorphisms on sex differences in structural brain abnormalities in schizophrenia assessed by magnetic resonance imaging. Archives of General Psychiatry 59, 154-164.
35. Gur RC, Gunning-Dixon F, Bilker WB, Gur RE (2002). Sex differences in temporo-limbic and frontal brain volumes of healthy adults. Cerebral Cortex 12, 998-1003.
36. Gur RE, Kohler C, Ragland JD, Siegel SJ, Bilker WB, Loughead J, Phend N, Gur RC (2003). Neurocognitive performance and clinical changes in olanzapine-treated patients with schizophrenia. Neuropsychopharmacology 28, 2029-2036.
37. Häfner H (2003). Gender differences in schizophrenia. Psychoneuroendocrinology 28 (Suppl. 2), 17-54.
38. Häfner H, Maurer K, Löffler W, Fätkenheuer B, an der Heiden W, Riecher-Rössler A, Behrens S, Gattaz W (1994). The epidemiology of early schizophrenia. Influence of age and gender on onset and early course. British Journal of Psychiatry 164 (Suppl. 23), 29-38.
39. Halari R, Mehrotra R, Sharma T, Ng V, Kumari V (2006b). Cognitive impairment but preservation of sexual dimorphism in cognitive abilities in chronic schizophrenia. Psychiatry Research 141, 129-139.
40. Halari R, Sharma T, Hines M, Andrew C, Simmons A, Kumari V (2006a). Comparable fMRI activity with differential behavioural performance on mental rotation and overt verbal fluency tasks in healthy men and women. Experimental Brain Research 169, 1-14.
41. Hall JA (1978). Gender effects in decoding non-verbal cues. Psychological Bulletin 85, 845-857.
42. Hall JA (1984). Non-verbal Sex Differences: Communication Accuracy and Expressive Style. John Hopkins University Press: Baltimore.
43. Halpern DF, LaMay LM (2000). The smarter sex: a critical review of sex differences in intelligence. Educational Psychology Review 12, 229-246.
44. Harasty J, Double KL, Halliday GM, Kril JJ, McRitchie DA (1997). Language-associated cortical regions are proportionally larger in the female brain. Archives of Neurology 54, 171-176.
45. Harvey PD, Napolitano JA, Mao L, Gharabawi G (2003). Comparative effects of risperidone and olanzapine on cognition in elderly patients with schizophrenia or schizoaffective disorder. International Journal of Geriatric Psychiatry 18, 820-829.
46. Hooker C, Park S (2002). Emotion processing and its relationship to social functioning in schizophrenia patients. Psychiatry Research 112, 41-50.
47. Iwanami A, Kanamori R, Isono H, Okajima Y, Kamijima K (1996). Impairment of inhibition of unattended stimuli in schizophrenic patients: event-related potential correlates during selective attention. Neuropsychobiology 34, 57-62.
48. Jordan K, Wustenberg T, Heinze HJ, Peters M, Jancke L (2002). Women and men exhibit different cortical activation patterns during mental rotation tasks. Neuropsychologia 40, 2397-2408.
49. Kay SR, Opler LA, Fiszbein A (1986). Positive and Negative Syndrome Scale (PANSS). MultiHealth Systems Inc.: North Tonawanda, NY.
50. Kimura D (1999). Sex and Cognition. The MIT Press: Cambridge, MA.
51. Kohler CG, Turner TH, Bilker WB, Brensinger CM, Siegel SJ, Kanes SJ, Gur RE, Gur RC (2003). Facial emotion recognition in schizophrenia: intensity effects and error pattern. American Journal of Psychiatry 160, 1768-1774.
52. Kucharska-Pietura K, David AS, Dropko P, Klimkowski M (2002). The perception of emotional chimeric faces in schizophrenia: further evidence of right hemisphere dysfunction. Neuropsychiatry, Neuropsychology and Behavioral Neurology 15, 72-78.
53. Leentjens AF, Wielaert SM, van Harskamp F, Wilmink FW (1998). Disturbances of affective prosody in patients with schizophrenia ; a cross sectional study. Journal of Neurology, Neurosurgery and Psychiatry 64, 375-378.
54. Leitman DI, Foxe JJ, Butler PD, Saperstein A, Revheim N, Javitt DC (2005). Sensory contributions to impaired prosodic processing in schizophrenia. Biological Psychiatry 58, 56-61.
55. Leung A, Chue P (2000). Sex differences in schizophrenia: a review of the literature. Acta Psychiatrica Scandinavia 101 (Suppl.), 3-38.
56. Linn MC, Petersen AC (1985). Emergence and characterization of sex differences in spatial ability: a meta-analysis. Child Development 56, 1479-1498.
57. Maki P, Rich J, Rosenbaum RS (2002). Implicit memory varies across the menstrual cycle: estrogen effects in young women. Neuropsychologia 40, 518-529.
58. Mandal MK, Pandey R, Prasad AB (1998). Facial expressions of emotions and schizophrenia: a review. Schizophrenia Bulletin 24, 399-412.
59. McClure EB (2000). A meta-analytic review of sex differences in facial expression processing and their development in infants, children, and adolescents. Psychological Bulletin 126, 424-453.
60. Mitchell RL, Elliott R, Barry M, Cruttenden A, Woodruff PW (2004). Neural response to emotional prosody in schizophrenia and in bipolar affective disorder. British Journal of Psychiatry 184, 223-230.
61. Mitchell TN, Free SL, Merschhemke M, Lemieux L, Sisodiya SM, Shorvon SD (2003). Reliable callosal measurement: population normative data confirm sex-related differences. American Journal of Neuroradiology 24, 410-418.
62. Moody MS (1997). Changes in scores on the mental rotation test during menstrual cycle. Perceptual and Motor Skills 84, 955-961.
63. Mueser K, Doonan R, Penn D, Blanchard J, Bellack A, Nishith P, DeLeon J (1996). Emotion recognition and social competence in chronic schizophrenia. Journal of Abnormal Psychology 105, 271-275.
64. Muller U, Werheid K, Hammerstein E, Jungmann S, Becker T (2005). Prefrontal cognitive deficits in patients with schizophrenia treated with atypical or conventional antipsychotics. European Psychiatry 20, 70-73.
65. Murphy D, Cutting J (1990). Prosodic comprehension and expression in schizophrenia. Journal of Neurology, Neurosurgery and Psychiatry 53, 727-730.
66. Nelson HE (1982). National Adult Reading Test (NART): Test Manual. NFER-Nelson: Windsor, UK.
67. Nestor PG, Han SD, Niznikiewicz M, Salisbury D, Spencer K, Shenton ME, McCarley RW (2001). Semantic disturbance in schizophrenia and its relationship to the cognitive neuroscience of attention. Biological Psychology 57, 23-46.
68. Penn D, Spaulding W, Reed D, Sullivan M (1996). The relationship of social cognition toward behaviour in chronic schizophrenia. Schizophrenia Research 20, 327-335.
69. Poole JH, Tobias F, Vinogradow S (2000). The functional relevance of affect recognition errors in schizophrenia. Journal of the International Neuropsychological Society 6, 649-658.
70. Raven JC, Court JH, Raven J (1996). Standard Progressive Matrices: with Adult US Norms. Oxford Psychologists: Oxford.
71. Rilea SL, Roskos-Ewoldsen B, Boles D (2004). Sex differences in spatial ability: a lateralization of function approach. Brain and Cognition 56, 332-343.
72. Roberts JE, Bell MA (2003). Two- and three-dimensional mental rotation tasks lead to different parietal laterality for men and women. International Journal of Psychophysiology 50, 235-246.
73. Ross ED, Orbelo DM, Cartwright J, Hansel S, Burgard M, Testa JA, Buck R (2001). Affective-prosodic deficits in schizophrenia: comparison to patients with brain damage and relation to schizophrenic symptoms [corrected]. Journal of Neurology, Neurosurgery and Psychiatry 70, 597-604. [Erratum in: Journal of Neurology, Neurosurgery and Psychiatry (2001) 71, 283.]
74. Rossell SL, Bullmore ET, Williams SC, David AS (2002). Sex differences in functional brain activation during a lexical visual field task. Brain and Language 80, 97-105.
75. Schirmer A, Kotz SA (2003). ERP evidence for a sex-specific Stroop effect in emotional speech. Journal of Cognitive Neuroscience 15, 1135-1148.
76. Schirmer A, Kotz SA, Friederici AD (2002). Sex differentiates the role of emotional prosody during word processing. Cognitive Brain Research 14, 228-233.
77. Schirmer A, Kotz SA, Friederici AD (2005). On the role of attention for the processing of emotions in speech: sex differences revisited. Brain Research. Cognitive Brain Research 24, 442-452.
78. Schirmer A, Zysset S, Kotz SA, Yves von Cramon D (2004). Gender differences in the activation of inferior frontal cortex during emotional speech perception. Neuroimage 21, 1114-1123.
79. Schlaepfer TE, Harris GJ, Tien AY, Peng L, Lee S, Pearlson GD (1995). Structural differences in the cerebral cortex of healthy female and male subjects: a magnetic resonance imaging study. Psychiatry Research 61, 129-135.
80. Schmand B, Lindeboom J, van Harskamp F (1992). Dutch Reading Test for Adults: Manual [Nederlandse leestest voor volwassenen: handleiding; NLV]. Swets & Zeitlinger: Lisse.
81. Scholten M, Aleman A, Montagne B, Kahn R (2005). Schizophrenia and processing of facial emotions: sex matters. Schizophrenia Research 78, 61-67.
82. Shaywitz BA, Shaywitz SE, Pugh KR, Constable RT, Skudlarski P, Fulbright RK, Bronen RA, Fletcher JM, Shankweiler DP, Katz L, Gore JC (1995). Sex differences in the functional organization of the brain for language. Nature 373, 607-609.
83. Comment in: Nature (1995) 373, 561-562.
84. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, Hergueta T, Baker R, Dunbar GC (1998). The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. Journal of Clinical Psychiatry 59, 22-33.
85. Shenton ME, Dickey CC, Frumin M, McCarley RW (2001). A review of MRI findings in schizophrenia. Schizophrenia Research 49, 1-52.
86. Shepard RN, Metzler J (1971). Mental rotation of three-dimensional objects. Science 171, 701-703.
87. Siegel-Hinson RI, McKeever WF (2002). Hemispheric specialisation, spatial activity experience, and sex differences on tests of mental rotation ability. Laterality 7, 59-74.
88. Silverman I, Phillips K (1993). Effects of oestrogen changes during the menstrual cycle on spatial performance. Ethology and Sociobiology 4, 257-270.
89. Tong Y, Gandour J, Talavage T, Wong D, Dzemidzic M, Xu Y, Li X, Lowe M (2005). Neural circuitry underlying sentence-level linguistic prosody. Neuroimage 28, 417-428.
90. Vingerhoets G, Berckmoes C, Stroobant N (2003). Cerebral hemodynamics during discrimination of prosodic and semantic emotion in speech studied by transcranial Doppler ultrasonography. Neuropsychology 17, 93-99.
91. Walder D, Seidman L, Cullen N, Su J, Tsuang M, Goldstein J (2006). Sex differences in language dysfunction in schizophrenia. American Journal of Psychiatry 163, 470-477.
92. Weiss E, Siedentopf CM, Hofer A, Deisenhammer EA, Hoptman MJ, Kremser C, Golaszewski S, Felber S, Fleischhacker WW, Delazer M (2003). Sex differences in brain activation pattern during a visuospatial cognitive task: a functional magnetic resonance imaging study in healthy volunteers. Neuroscience Letters 344, 169-172.
93. Woodruff PW, Wright IC, Bullmore ET, Brammer M, Howard RJ, Williams SC, Shapleske J, Rossell S, David AS, McGuire PK, Murray RM (1997). Auditory hallucinations and the temporal cortical response to speech in schizophrenia: a functional magnetic resonance imaging study. American Journal of Psychiatry 154, 1676-1682.
94. Wright IC, Rabe-Hesketh S, Woodruff PW, David AS, Murray RM, Bullmore ET (2000). Meta-analysis of regional brain volumes in schizophrenia. American Journal of Psychiatry 157, 16-25.