Hemidesmus indicus Protects against ethanol-induced liver toxicity

Cellular and Molecular Biology Letters

Volumn 13, Issue 1, 2008, Pages 20-37

  Saravanan, Nadana ^a   Nalini, Namasivayam ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

FT IR spectroscopy; Hemidesmus indicus; Lipid peroxidation; Rat liver

Indexed keywords

ANIMALIA; HEMIDESMUS INDICUS; RATTUS;

ALBUMIN; ALCOHOL; CERULOPLASMIN; GLOBULIN; GLUTATHIONE; GLYCOGEN; HEMIDESMUS INDICUS EXTRACT; PROTEIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOCHEMISTRY; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; FOOD INTAKE; GLYCOGEN LIVER LEVEL; HEMIDESMUS INDICUS; INFRARED SPECTROSCOPY; LIPID PEROXIDATION; LIVER; LIVER INJURY; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN; PLANT ROOT; PROTEIN BLOOD LEVEL; RAT; WEIGHT GAIN;

EID: 43549122349     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-007-0032-z     Document Type: Article

References (73)

1. Diehl, A.M. Liver disease in alcohol abusers: clinical perspective. Alcohol27 (2002) 7–11.
2. Lin, C.N., Chung, M.I. and Gan, K.H. Novel antihepatotoxic principles of Solanum incanum. Planta Med. 54 (1988) 222.
3. Zima, T., Fialova, L., Mestek, O., Janebova, M., Crkovska, J., Malbohan, I., Stipek, S., Mikulikova, L. and Popov, P. Oxidative stress, metabolism of ethanol and alcohol-related diseases. J. Biomed. Sci.1 (2001) 59–70.
4. Plaa, G.L. and Witschi, H. Chemicals, drugs and lipid peroxidation. Annu. Rev. Pharmacol. Toxicol.6 (1976) 125–141.
5. Cederbaum, A.I. Role of lipid peroxidation and oxidative stress in alcohol toxicity. Free Radic. Biol. Med.7 (1989) 537–539.
6. Lewis, R.N.A.H. and McElhaney, R.N. Fourier transform infrared spectroscopy in the study of hydrated lipids and lipid bilayer membranes. In: Infrared Spectroscopy of Biomolecules (Mantsch, H.H. and Chapman D., Eds.) Wiley-Liss, New York, 1996, 159.
7. Wong, P.T.T., Lacelle, S. and Yazdi, H.M. Normal and malignant human colonic tissues investigated by pressure-tunning FT-IR spectroscopy. Appl. Spectrosc.47 (1993) 1830–1836.
8. Severcan, F., Gorgulu, G., Gorgulu, S.T. and Guray, T. Rapid monitoring of diabetes-induced lipid peroxidation by Fourier transform infrared spectroscopy: Evidence from rat liver microsomal membranes. Anal. Biochem.339 (2005) 36–40.
9. Galin, D., Gridina, N.Y., Kruglova F.B. and Pushchuk, O.P. FT-IR spectroscopy studies of nucleic acids damage. Talanta53 (2000) 233–246.
10. Kerai, M.D.J., Waterfield, C.J., Kenyon, S.H., Asker, D.S. and Timbrell, J.A. Reversal of ethanol induced hepatic steatosis and lipidperoxidation by taurine: a study in rats. Alcohol34 (1999) 529–541.
11. Saravanan, R., Viswanathan, P. and Pugalendi, K.V. Protective effect of ursolic acid on ethanol-mediated experimental liver damage in rats. Life Sci.78 (2006) 713–718.
12. Alam, M. I., Auddy, B. and Gomes, A. Isolation, purification and partial characterization of viper venom inhibiting factor from the root extract of the Indian medicinal plant sarsaparilla (Hemidesmus indicus R.Br). Toxicon2 (1994) 1551–1557.
13. Saravanan, N., Rajasankar, S. and Nalini, N. Antioxidant effect of 2-hydroxy 4-methoxy benzoic acid on ethanol-induced hepatotoxicity in rats. J. Pharm. Pharmacol.59 (2007) 445–453.
14. Prabakan, M., Anandan, R. and Devaki, T. Protective effect of Hemidesmus indicus against rifampicin and isoniazid-induced hepatotoxicity in rats. Fitoterapia71 (2000) 55–59.
15. Baheti, J.R., Goyal, R.K. and Shah, G.B. Hepatoprotective activity of Hemidesmus indicus R.Br.in rats. Indian J. Exp. Biol.44 (2006) 399–402.
16. Sarasan, V., Soniya, E.V. and Nair, G.M. Regeneration of Indian sarasaparilla, Hemidesmus indicus R.Br. through organogenesis and somatic embryogenesis. Indian J. Exp. Biol.32 (1994) 284–287.
17. Anonymous. Indian Pharmacopoeia, second edition. Government of India, New Delhi, 1966, 57.
18. Verma, P.R., Joharapurkar, A.A., Chatpalliwar, V.A., Asnani, A.J. Antinociceptive activity of alcoholic extract of Hemidesmus indicus R.Br. in mice. J. Ethnopharmacol.102 (2005) 298–301.
19. Enomoto, N., Yamashina, S., Kono, H., Schemmer, P., Rivera, C.A., Enomoto, A., Nishiura, T., Nishimura, T., Brenner, D.A. and Thurman, R.G. Development of a new, simple rat model of early alcohol-induced liver injury based on sensitization of Kupffer cells. Hepatology29 (1999) 1680–1689.
20. Das, S., Prakash, R. and Devaraj, S.N. Antidiarrhoeal effects of methanolic root extract of Hemidesmus indicus (Indian sarsaparilla) — an in vitro and in vivo study. Indian J. Exp. Biol.41 (2003) 363–366.
21. Ohkawa, H., Ohishi, N. and Yagi, K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem.95 (1979) 351–358.
22. Yagi, K. Lipid peroxides and human disease. Chem. Physiol. Lipids45 (1978) 337–351.
23. Reitman, S. and Frankel, S. A colorimetric method for the determination of serum glutamate oxaloacetic and glutamate pyruvic transaminases. Am. J. Clin. Pathol.28 (1957) 56–63.
24. Kind, P.R.N. and King, E.J. Estimation of plasma phosphatases by determination of hydrolyzed phenol with amino-antipyrine. J. Clin. Path.7 (1954) 330–322.
25. King, J. Practical clinical enzymology (Van, D. Ed.) Nastrand Co., London, 1965, 83–93.
26. Rosalki, S.B. and Rau, D. Serum gamma-glutamyl transpeptidase activity in alcoholism. Clin. Chem. Acta39 (1972) 41–47.
27. Rotruck, J.T., Pope, A.L., Ganther, H.E., Swanson, A.B., Hafeman, D.G. and Hoekstra, W.G. Selenium: biochemical role as a component of glutathione peroxidase. Science179 (1973) 588–590.
28. Ellman, G.L. Tissue sulfhydryl groups. Arch. Biochem. Biophys.82 (1959) 70–77.
29. Carlberg, I. and Mannervik, B. Purification and characterization of the flavoenzyme glutathione reductase from rat liver. J. Biol. Chem.250 (1975) 5475–5480.
30. Habig, W.H. and Jakoby, W.B. Glutathione-S-transferases (rat and human). Methods Enzymol.77 (1981) 218–231.
31. Lowry, O.H. Roseborough, N.J. Farr, A.L. and Randal, R.J. Protein measurement with Folin’s phenol reagent. J. Biol. Chem.193 (1951) 265–275.
32. Reinhold, J.G. In: Standard methods in clinical chemistry (Reiner, M. Ed.), Academic Press, New York, 1953, 88.
33. Ravin, H.A. An improved colorimetric enzymatic assay of ceruloplasmin. J. Lab. Clin. Med.58 (1961)161–168.
34. Morales, M.A., Jabbagry A.J. and Terenizi, H.R. Neurospora News Lett.20 (1973) 24.
35. Severcan, F., Toyran, N., Kaptan, N. and Turan, B. Fourier transform infrared study of the effect of diabetes on rat liver and heart tissues in the C-H region. Talanta53 (2000) 55–59.
36. Jagadeesan, G., Kavitha A.V. and Subashini J. FT-IR study of the influence of Tribulus terrestris on mercury intoxicated mice, Mus musculus liver. Trop. Biomed.22 (2005) 15–22.
37. Pirola, R.C. and Lieber, C.S. Energy wastage in rats given drugs that induce microsomal enzymes. J. Nutr.105 (1975) 1544–1548.
38. Lieber, C.S. Alcohol, liver and nutrition. J. Am. Coll. Nutr.10 (1991) 602–632.
39. Baldi, E., Burra, P., Plebani, M. and Salvagnini, M. Serum malondialdehyde and mitochondrial aspartate aminotransferase activity as markers of chronic alcohol intake and alcoholic liver disease. Ital. J. Gastrol.25 (1993) 429–432.
40. Goldberg, D.M. and Watts, C. Serum enzyme changes as evidence of liver reaction to oral alcohol. Gastroenterology49 (1965) 256–261.
41. Friedman, R.B., Anderson, R.E., Entine, S.M. and Hirshberg, S.B. Effects of diseases on clinical laboratory tests. Clin. Chem.6 (1980) 1D–476D.
42. Ahmed, B., Alam, T., Varshney, M. and Khan, A.S. Hepatoprotective activity of two plants belonging to the Apiaceae and the Euphorbiaceae family. J. Ethnopharmacol.79 (2002) 313–316.
43. Bucher, J.R., Tien, M. and Aust, S.D. The requirement of ferric ion in the initiation of lipid peroxidation by chelated ferrous ion. Biochem. Biophys. Res. Commun.111 (1983) 777–784.
44. Dormandy, T.L. Free radical reactions in biological systems. Ann. R. Coll. Surg. Engl.62 (1980)188–194.
45. Van Horn, C.G., Ivester, P. and Cunningham, C.C. Chronic ethanol consumption and liver glycogen synthesis. Arch. Biochem. Biophys.392 (2001) 145–152.
46. Porter, N.A., Caldwell, S.E. and Mills, K.A. Mechanisms of free radical oxidation of unsaturated lipids. Lipids30 (1995) 277–290.
47. Nordmann, R. Alcohol and antioxidant systems. Alcohol29 (1994) 513–522.
48. Ikuo, N., Masako, H., Hiroshi, T., Mitsuaki, M., and Kunio, Y. Lipid peroxide levels of serum lipoprotein fractions of diabetic patients. Biochem. Med.25 (1991) 373–378.
49. Winrow, V.R., Winyard, P.G., Morris, C.J. and Black, D.R. Free radicals in inflammation: Secondary messengers and mediators of tissue destruction. Br. Med. Bull.49 (1993) 506–517.
50. Santiard, D., Ribiere, C., Nordmann, R. and Houee-Levin, C. Inactivation of Cu, Zn-superoxide dismutase by free radicals derived from ethanol metabolism: a gamma radiolysis study. Free Radic. Biol. Med.19 (1995) 121–127.
51. Mary, N.K. Achuthan, C.R. Babu, B.H. and Padikkala, J. In vitro antioxidant and antithrombotic activity of Hemidesmus indicus (L) R.Br. J. Ethnopharmacol. 87 (2003) 187–191.
52. Pares, A. Planas, R. Torres, M. Caballeria, J. Viver, J.M. Acero, D. Panes, J. Rigau, J. Santos, J. and Rodes, J. Effect of silymarin in alcoholic patients with cirrhosis of the liver: results of a controlled, double-blind, randomized and multicentral trial. J. Hepatol.28 (1998) 615–621.
53. Reed, D.J. Glutathione: toxicological implications. Annu. Rev. Pharmacol. Toxicol.30 (1990) 603–631.
54. Hayes, J.D. and Pulford, D.J. The glutathione-S-transferase supergene family: Regulation of GST and the contribution of isoenzymes to cancer protection and drug resistance. Crit. Rev. Biochem. Mol. Biol.35 (1995) 455–600.
55. Bladeren, P.J.V. and Ommen, B.V. The inhibition of glutathione-S-transferase: mechanisms, toxic consequences and therapeutic benefits. Pharmacol. Ther.51 (1991) 35–46.
56. Balasubramaniyan, V., Kalaivani Sailaja, J. and Nalini, N. Role of leptin on alcohol induced oxidative stress. Pharmacol. Res.47 (2003) 211–216.
57. Ravishankara, M.N., Shrivastava, N., Padh, H. and Rajani, M. Evaluation of antioxidant properties of root bark of Hemidesmus indicus R. Br. (Anantmul). Phytomedicine9 (2002) 153–60.
58. Garcia-Ruiz, C., Morales, A., Colell, A., Ballesta, A., Rodes, J., Kaplowitz, N. and Fernandez-Checa, J.C., Feeding S-adenosyl-L-methionine attenuates both ethanol-induced depletion of mitochondrial glutathione and mitochondrial dysfunction in periportal and perivenous rat hepatocytes. Hepatology21 (1995) 207–214.
59. Iimuro, Y., Bradford, B.U., Yamashina, S., Rusyn, I., Nakagami, M., Enomoto, N., Kono, H., Frey, W., Forman, D., Brenner, D. and Thurman, R.G. The glutathione precursor L-2-oxothiazolidine-4-carboxylic acid protects against liver injury due to chronic enteral ethanol exposure in the rat. Hepatology31 (2000) 391–398.
60. Priyadarsini, K.I., Maity, D.K., Naik, G.H., Kumar, M.S., Unnikrishnan, M.K., Satav, J.G. and Mohan, H. Role of phenolic O-H and methylene hydrogen on the free radical reactions and antioxidant activity of curcumin. Free Radic. Biol. Med.35 (2003) 475–484.
61. Sroka, Z. and Cisowski, W. Hydrogen peroxide scavenging, antioxidant and anti-radical activity of some phenolic acids. Food Chem. Toxicol.1 (2003) 753–758.
62. Adak, S., Mazumder, A. and Banerjee, R.K. Probing the active site residues in aromatic donor oxidation in horseradish peroxidase involvement of an arginine and a tyrosine residue in aromatic donor binding. Biochem. J.314 (1996) 985–991.
63. 2-horseradish peroxidase chemiluminescence. J. Biolumin. Chemilumin.13 (1998) 75–84.
64. Alanko, J., Riutta, A., Holm, P., Mucha, I., Vapaatalo, H. and Metsa-Ketela, T. Modulation of arachidonic acid metabolism by phenols: Relation to their structure and antioxidant properties. Free Radic. Biol. Med.26 (1999) 193–201.
65. Halliwell, B. and Chirico, S. Lipid peroxidation: Its mechanism, measurement, and significance. Am. J. Clin. Nutr.57 (1993) 715–725.
66. nd edition, Freeman, W.H. and Company, New York, 1982.
67. Toyran, N., Zorlu, F., Donmez, G., Oge, K. and Severcan, F., Chronic hypoperfusion alters the content and structure of proteins and lipids of rat brain homogenates: a Fourier transform infrared spectroscopy study. Eur. Biophys. J.33 (2004) 549–554.
68. Severcan, F., Sahin, I. and Kazanci, N. Melatonin strongly interacts with zwitterionic model membranes-evidence from Fourier transform. Biochim. Biophys. Acta1668 (2005) 215–222.
69. Mantsch, H.H., and Chapman, D. (Eds) Infrared Spectroscopy of Biomolecules, Wiley, New York, 1996.
70. 2+ on phospholipid model membranes: An FT-IR study. Chem. Phys. Lipids123 (2003) 165–176.
71. Liu, K.Z., Bose, R. and Mantsch, H.H Infrared spectroscopic study of diabetic platelets. Vibrat. Spec.860 (2002) 1–6.
72. MacSween, R.N. and Burt, A.D. Histologic spectrum of alcoholic liver disease. Semin. Liver Dis.6 (1986) 221–232.
73. Sarkar, S.N., Chattopadhyay, S.K. and Majumdar, A.C. Subacute toxicity of urea herbicide, isoproturon in male rats. Indian J. Exp. Biol.33 (1995) 851–856.