메뉴 건너뛰기




Volumn 9, Issue 5, 2008, Pages 491-496

DNAM-1: An amplifier of immune responses as a therapeutic target in various disorders

Author keywords

Adhesion molecule; Allergic inflammation; Cancer; Co stimulatory molecule; Glycoprotein

Indexed keywords

CELL ADHESION MOLECULE; DNAX ACCESSORY MOLECULE 1; GLYCOPROTEIN; LIGAND; NECTIN 2; VIRUS RECEPTOR;

EID: 43549105875     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (14)

References (55)
  • 1
    • 35548982621 scopus 로고    scopus 로고
    • Immunoglobulin superfamily cell adhesion molecules: Zippers and signals
    • Aricescu AR, Jones EY: Immunoglobulin superfamily cell adhesion molecules: Zippers and signals. Curr Opin Cell Biol (2007) 19(5):543-550.
    • (2007) Curr Opin Cell Biol , vol.19 , Issue.5 , pp. 543-550
    • Aricescu, A.R.1    Jones, E.Y.2
  • 2
    • 27244451493 scopus 로고    scopus 로고
    • Co-stimulatory pathways in lymphocyte regulation: The immunoglobulin superfamily
    • Peggs KS, Allison JP: Co-stimulatory pathways in lymphocyte regulation: The immunoglobulin superfamily. Br J Haematol (2005) 130(6):809-824.
    • (2005) Br J Haematol , vol.130 , Issue.6 , pp. 809-824
    • Peggs, K.S.1    Allison, J.P.2
  • 3
    • 34447518913 scopus 로고    scopus 로고
    • Mast cells as effector cells: A co-stimulating question
    • Bachelet I, Levi-Schaffer F: Mast cells as effector cells: A co-stimulating question. Trends Immunol (2007) 28(8):360-365.
    • (2007) Trends Immunol , vol.28 , Issue.8 , pp. 360-365
    • Bachelet, I.1    Levi-Schaffer, F.2
  • 4
    • 0042877332 scopus 로고    scopus 로고
    • Immune regulation by novel costimulatory molecules
    • Dong C, Nurieva RI, Prasad DV: Immune regulation by novel costimulatory molecules. Immunol Res (2003) 28(1):39-48.
    • (2003) Immunol Res , vol.28 , Issue.1 , pp. 39-48
    • Dong, C.1    Nurieva, R.I.2    Prasad, D.V.3
  • 6
    • 25844456563 scopus 로고    scopus 로고
    • T-cell costimulatory molecules: Optimal targets for the treatment of allergic airway disease with monoclonal antibodies
    • Kroczek R, Hamelmann E: T-cell costimulatory molecules: Optimal targets for the treatment of allergic airway disease with monoclonal antibodies. J Allergy Clin Immunol (2005) 116(4):906-909.
    • (2005) J Allergy Clin Immunol , vol.116 , Issue.4 , pp. 906-909
    • Kroczek, R.1    Hamelmann, E.2
  • 7
    • 0034940822 scopus 로고    scopus 로고
    • Costimulatory molecules and their ligands as therapeutic targets in autoimmune disease
    • Zöller M: Costimulatory molecules and their ligands as therapeutic targets in autoimmune disease. Eur J Dermatol (2001) 11(4):335-342.
    • (2001) Eur J Dermatol , vol.11 , Issue.4 , pp. 335-342
    • Zöller, M.1
  • 8
    • 33748749503 scopus 로고    scopus 로고
    • Bachelet I, Munitz A, Mankutad D, Levi-Schaffer F: Mast cell costimulation by CD226/CD112 (DNAM-1/nectin-2): A novel interface in the allergic process. J Biol Chem (2006) 281(37):27190-27196. • This is the first paper that implicates DNAM-1 in allergic inflammation. The researchers provided evidence that this molecule synergizes with the FcεRI receptor to augment the activation of mast cells.
    • Bachelet I, Munitz A, Mankutad D, Levi-Schaffer F: Mast cell costimulation by CD226/CD112 (DNAM-1/nectin-2): A novel interface in the allergic process. J Biol Chem (2006) 281(37):27190-27196. • This is the first paper that implicates DNAM-1 in allergic inflammation. The researchers provided evidence that this molecule synergizes with the FcεRI receptor to augment the activation of mast cells.
  • 10
    • 0042572415 scopus 로고    scopus 로고
    • The expression, regulation and adhesion function of a novel CD molecule, CD226, on human endothelial cells
    • Chen L, Xie X, Zhang X, Jia W, Jian J, Song C, Jin B: The expression, regulation and adhesion function of a novel CD molecule, CD226, on human endothelial cells. Life Sci (2003) 73(18):2373-2382.
    • (2003) Life Sci , vol.73 , Issue.18 , pp. 2373-2382
    • Chen, L.1    Xie, X.2    Zhang, X.3    Jia, W.4    Jian, J.5    Song, C.6    Jin, B.7
  • 12
    • 0141703595 scopus 로고    scopus 로고
    • Kojima H, Kanada H, Shimizu S, Kasama E, Shibuya K, Nakauchi H, Nagasawa T, Shibuya A: CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells. J Biol Chem (2003) 278(38):36748- 36753. • An elegant study that demonstrated that DNAM-1 is expressed on endothelial cells, and can induce their activation and aggregation.
    • Kojima H, Kanada H, Shimizu S, Kasama E, Shibuya K, Nakauchi H, Nagasawa T, Shibuya A: CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells. J Biol Chem (2003) 278(38):36748- 36753. • An elegant study that demonstrated that DNAM-1 is expressed on endothelial cells, and can induce their activation and aggregation.
  • 13
    • 20044376867 scopus 로고    scopus 로고
    • CD226 is expressed on the megakaryocytic lineage from hematopoietic stem cells/progenitor cells and involved in its polyploidization
    • Ma D, Sun Y, Lin D, Wang H, Dai B, Zhang X, Ouyang W, Jian J, Jia W, Xu X, Jin B: CD226 is expressed on the megakaryocytic lineage from hematopoietic stem cells/progenitor cells and involved in its polyploidization. Eur J Haematol (2005) 74(3):228-240.
    • (2005) Eur J Haematol , vol.74 , Issue.3 , pp. 228-240
    • Ma, D.1    Sun, Y.2    Lin, D.3    Wang, H.4    Dai, B.5    Zhang, X.6    Ouyang, W.7    Jian, J.8    Jia, W.9    Xu, X.10    Jin, B.11
  • 14
    • 4043099715 scopus 로고    scopus 로고
    • The LFA-1-associated molecule PTA-1 (CD226) on T cells forms a dynamic molecular complex with protein 4.1G and human discs large
    • Ralston KJ, Hird SL, Zhang X, Scott JL, Jin B, Thorne RF, Berndt MC, Boyd AW, Burns GF: The LFA-1-associated molecule PTA-1 (CD226) on T cells forms a dynamic molecular complex with protein 4.1G and human discs large. J Biol Chem (2004) 279(32):33816-33828.
    • (2004) J Biol Chem , vol.279 , Issue.32 , pp. 33816-33828
    • Ralston, K.J.1    Hird, S.L.2    Zhang, X.3    Scott, J.L.4    Jin, B.5    Thorne, R.F.6    Berndt, M.C.7    Boyd, A.W.8    Burns, G.F.9
  • 15
    • 15844375309 scopus 로고    scopus 로고
    • Shibuya A, Campbell D, Hannum C, Yssel H, Franz-Bacon K, McClanahan T, Kitamura T, Nicholl J, Sutherland GR, Lanier LL, Phillips JH: DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. Immunity (1996) 4(6):573-581. •• This study was the first to describe the expression and structure of DNAM-1, and demonstrated its functionality in mediating immune cytotoxicity.
    • Shibuya A, Campbell D, Hannum C, Yssel H, Franz-Bacon K, McClanahan T, Kitamura T, Nicholl J, Sutherland GR, Lanier LL, Phillips JH: DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. Immunity (1996) 4(6):573-581. •• This study was the first to describe the expression and structure of DNAM-1, and demonstrated its functionality in mediating immune cytotoxicity.
  • 16
    • 0032529628 scopus 로고    scopus 로고
    • Shibuya A, Lanier LL, Phillips JH: Protein kinase C is involved in the regulation of both signaling and adhesion mediated by DNAX accessory molecule-1 receptor. J Immunol (1998) 161(4):1671-1676. • In this paper, the researchers demonstrated the significance of PKC in phosphorylating the DNAM-1 molecule and inducing its activity for the first time.
    • Shibuya A, Lanier LL, Phillips JH: Protein kinase C is involved in the regulation of both signaling and adhesion mediated by DNAX accessory molecule-1 receptor. J Immunol (1998) 161(4):1671-1676. • In this paper, the researchers demonstrated the significance of PKC in phosphorylating the DNAM-1 molecule and inducing its activity for the first time.
  • 18
    • 14944364789 scopus 로고    scopus 로고
    • Requirement of the serine at residue 329 for lipid raft recruitment of DNAM-1 (CD226)
    • Shirakawa J, Shibuya K, Shibuya A: Requirement of the serine at residue 329 for lipid raft recruitment of DNAM-1 (CD226). Int Immunol (2005) 17(3):217-223.
    • (2005) Int Immunol , vol.17 , Issue.3 , pp. 217-223
    • Shirakawa, J.1    Shibuya, K.2    Shibuya, A.3
  • 21
    • 14844318011 scopus 로고    scopus 로고
    • Identification and characterization of murine DNAM-1 (CD226) and its poliovirus receptor family ligands
    • Tahara-Hanaoka S, Miyamoto A, Hara A, Honda S, Shibuya K, Shibuya A: Identification and characterization of murine DNAM-1 (CD226) and its poliovirus receptor family ligands. Biochem Biophys Res Commun (2005) 329(3):996-1000.
    • (2005) Biochem Biophys Res Commun , vol.329 , Issue.3 , pp. 996-1000
    • Tahara-Hanaoka, S.1    Miyamoto, A.2    Hara, A.3    Honda, S.4    Shibuya, K.5    Shibuya, A.6
  • 22
    • 33750951313 scopus 로고    scopus 로고
    • Expression of human CD226 on T cells and natural killer cells and of soluble CD226 in plasma of HIV-1-infected Chinese patients
    • Ye X, Zhang Z, Jiang Y, Han X, Wang Y, Zhang M, Liu J, Geng W, Dai D, Shi W, Shang H: Expression of human CD226 on T cells and natural killer cells and of soluble CD226 in plasma of HIV-1-infected Chinese patients. Viral Immunol (2006) 19(3):576-581.
    • (2006) Viral Immunol , vol.19 , Issue.3 , pp. 576-581
    • Ye, X.1    Zhang, Z.2    Jiang, Y.3    Han, X.4    Wang, Y.5    Zhang, M.6    Liu, J.7    Geng, W.8    Dai, D.9    Shi, W.10    Shang, H.11
  • 24
    • 26844537217 scopus 로고    scopus 로고
    • V α 24-invariant NKT cells from patients with allergic asthma express CCR9 at high frequency and induce Th2 bias of CD3+ T cells upon CD226 engagement
    • Sen Y, Yongyi B, Yuling H, Luokun X, Li H, Jie X, Tao D, Gang Z, Junyan L, Chunsong H, Zhang X et al: V α 24-invariant NKT cells from patients with allergic asthma express CCR9 at high frequency and induce Th2 bias of CD3+ T cells upon CD226 engagement. J Immunol (2005) 175(8):4914-4926.
    • (2005) J Immunol , vol.175 , Issue.8 , pp. 4914-4926
    • Sen, Y.1    Yongyi, B.2    Yuling, H.3    Luokun, X.4    Li, H.5    Jie, X.6    Tao, D.7    Gang, Z.8    Junyan, L.9    Chunsong, H.10    Zhang, X.11
  • 25
    • 1642394991 scopus 로고    scopus 로고
    • Cutting edge: CD96 (Tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155)
    • Fuchs A, Cella M, Giurisato E, Shaw AS, Colonna M: Cutting edge: CD96 (Tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155). J Immunol (2004) 172(7):3994- 3998.
    • (2004) J Immunol , vol.172 , Issue.7 , pp. 3994-3998
    • Fuchs, A.1    Cella, M.2    Giurisato, E.3    Shaw, A.S.4    Colonna, M.5
  • 26
    • 33748170117 scopus 로고    scopus 로고
    • The role of NK cell recognition of nectin and nectin-like proteins in tumor immunosurveillance
    • Fuchs A, Colonna M: The role of NK cell recognition of nectin and nectin-like proteins in tumor immunosurveillance. Semin Cancer Biol (2006) 16(5):359-366.
    • (2006) Semin Cancer Biol , vol.16 , Issue.5 , pp. 359-366
    • Fuchs, A.1    Colonna, M.2
  • 27
    • 33746063259 scopus 로고    scopus 로고
    • Is the CD200/CD200 receptor interaction more than just a myeloid cell inhibitory signal?
    • Minas K, Liversidge J: Is the CD200/CD200 receptor interaction more than just a myeloid cell inhibitory signal? Crit Rev Immunol (2006) 26(3):213-230.
    • (2006) Crit Rev Immunol , vol.26 , Issue.3 , pp. 213-230
    • Minas, K.1    Liversidge, J.2
  • 29
    • 0042922822 scopus 로고    scopus 로고
    • Identification of PVR (CD155) and nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule
    • First delineation of PVR and nectin-2 as DNAM-1 ligands, ••
    • Bottino C, Castriconi R, Pende D, Rivera P, Nanni M, Carnemolla B, Cantoni C, Grassi J, Marcenaro S, Reymond N, Vitale M et al: Identification of PVR (CD155) and nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule. J Exp Med (2003) 198(4):557-567. •• First delineation of PVR and nectin-2 as DNAM-1 ligands.
    • (2003) J Exp Med , vol.198 , Issue.4 , pp. 557-567
    • Bottino, C.1    Castriconi, R.2    Pende, D.3    Rivera, P.4    Nanni, M.5    Carnemolla, B.6    Cantoni, C.7    Grassi, J.8    Marcenaro, S.9    Reymond, N.10    Vitale, M.11
  • 32
    • 38049132085 scopus 로고    scopus 로고
    • Interaction of cancer cells with platelets mediated by necl-5/poliovirus receptor enhances cancer cell metastasis to the lungs
    • Morimoto K, Satoh-Yamaguchi K, Hamaguchi A, Inoue Y, Takeuchi M, Okada M, Ikeda W, Takai Y, Imai T: Interaction of cancer cells with platelets mediated by necl-5/poliovirus receptor enhances cancer cell metastasis to the lungs. Oncogene (2008) 27(3):264-273.
    • (2008) Oncogene , vol.27 , Issue.3 , pp. 264-273
    • Morimoto, K.1    Satoh-Yamaguchi, K.2    Hamaguchi, A.3    Inoue, Y.4    Takeuchi, M.5    Okada, M.6    Ikeda, W.7    Takai, Y.8    Imai, T.9
  • 34
    • 10844246498 scopus 로고    scopus 로고
    • Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: Critical role of DNAX accessory molecule-1-poliovirus receptor interaction
    • Castriconi R, Dondero A, Corrias MV, Lanino E, Pende D, Moretta L, Bottino C, Moretta A: Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: Critical role of DNAX accessory molecule-1-poliovirus receptor interaction. Cancer Res (2004) 64(24):9180-9184.
    • (2004) Cancer Res , vol.64 , Issue.24 , pp. 9180-9184
    • Castriconi, R.1    Dondero, A.2    Corrias, M.V.3    Lanino, E.4    Pende, D.5    Moretta, L.6    Bottino, C.7    Moretta, A.8
  • 38
    • 20144385362 scopus 로고    scopus 로고
    • Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: Evidence for the involvement of the poliovirus receptor (CD155) and nectin-2 (CD112)
    • Pende D, Spaggiari GM, Marcenaro S, Martini S, Rivera P, Capobianco A, Falco M, Lanino E, Pierri I, Zambello R, Bacigalupo A et al: Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: Evidence for the involvement of the poliovirus receptor (CD155) and nectin-2 (CD112). Blood (2005) 105(5):2066-2073.
    • (2005) Blood , vol.105 , Issue.5 , pp. 2066-2073
    • Pende, D.1    Spaggiari, G.M.2    Marcenaro, S.3    Martini, S.4    Rivera, P.5    Capobianco, A.6    Falco, M.7    Lanino, E.8    Pierri, I.9    Zambello, R.10    Bacigalupo, A.11
  • 39
    • 35048884094 scopus 로고    scopus 로고
    • Peritoneal natural killer cells from epithelial ovarian cancer patients show an altered phenotype and bind to the tumour marker MUC16 (CA125)
    • Belisle JA, Gubbels JA, Raphael CA, Migneault M, Rancourt C, Connor JP, Patankar MS: Peritoneal natural killer cells from epithelial ovarian cancer patients show an altered phenotype and bind to the tumour marker MUC16 (CA125). Immunology (2007) 122(3):418-429.
    • (2007) Immunology , vol.122 , Issue.3 , pp. 418-429
    • Belisle, J.A.1    Gubbels, J.A.2    Raphael, C.A.3    Migneault, M.4    Rancourt, C.5    Connor, J.P.6    Patankar, M.S.7
  • 40
    • 34447266954 scopus 로고    scopus 로고
    • Scanning copy number and gene expression on the 18q21-qter chromosomal region by the systematic multiplex PCR and reverse transcription-PCR methods
    • Yamamoto F, Yamamoto M: Scanning copy number and gene expression on the 18q21-qter chromosomal region by the systematic multiplex PCR and reverse transcription-PCR methods. Electrophoresis (2007) 28(12):1882-1895.
    • (2007) Electrophoresis , vol.28 , Issue.12 , pp. 1882-1895
    • Yamamoto, F.1    Yamamoto, M.2
  • 42
    • 34250210260 scopus 로고    scopus 로고
    • Expression and possible role of PVR/CD155/necl-5 in osteoclastogenesis
    • Kakehi S, Nakahama K, Morita I: Expression and possible role of PVR/CD155/necl-5 in osteoclastogenesis. Mol Cell Biochem (2007) 301(1-2):209-217.
    • (2007) Mol Cell Biochem , vol.301 , Issue.1-2 , pp. 209-217
    • Kakehi, S.1    Nakahama, K.2    Morita, I.3
  • 43
    • 2942571936 scopus 로고    scopus 로고
    • Ligand stimulation of CD155α inhibits cell adhesion and enhances cell migration in fibroblasts
    • Oda T, Ohka S, Nomoto A: Ligand stimulation of CD155α inhibits cell adhesion and enhances cell migration in fibroblasts. Biochem Biophys Res Commun (2004) 319(4):1253-1264.
    • (2004) Biochem Biophys Res Commun , vol.319 , Issue.4 , pp. 1253-1264
    • Oda, T.1    Ohka, S.2    Nomoto, A.3
  • 45
    • 33344469008 scopus 로고    scopus 로고
    • Expression of the DNAM-1 ligands, nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: Relevance for natural killer-dendritic cell interaction
    • Pende D, Castriconi R, Romagnani P, Spaggiari GM, Marcenaro S, Dondero A, Lazzeri E, Lasagni L, Martini S, Rivera P, Capobianco A et al: Expression of the DNAM-1 ligands, nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: Relevance for natural killer-dendritic cell interaction. Blood (2006) 107(5):2030-2036.
    • (2006) Blood , vol.107 , Issue.5 , pp. 2030-2036
    • Pende, D.1    Castriconi, R.2    Romagnani, P.3    Spaggiari, G.M.4    Marcenaro, S.5    Dondero, A.6    Lazzeri, E.7    Lasagni, L.8    Martini, S.9    Rivera, P.10    Capobianco, A.11
  • 47
    • 30144443832 scopus 로고    scopus 로고
    • Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion
    • Bryceson YT, March ME, Ljunggren HG, Long EO: Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion. Blood (2006) 107(1):159-166.
    • (2006) Blood , vol.107 , Issue.1 , pp. 159-166
    • Bryceson, Y.T.1    March, M.E.2    Ljunggren, H.G.3    Long, E.O.4
  • 49
    • 34247584482 scopus 로고    scopus 로고
    • Generation of rat monoclonal antibodies against murine PTA1/CD226
    • Wang D, Zhang X, Xu X, Song C, Xu Z, Jin B: Generation of rat monoclonal antibodies against murine PTA1/CD226. Hybridoma (2007) 26(2):73-77.
    • (2007) Hybridoma , vol.26 , Issue.2 , pp. 73-77
    • Wang, D.1    Zhang, X.2    Xu, X.3    Song, C.4    Xu, Z.5    Jin, B.6
  • 50
    • 33750353273 scopus 로고    scopus 로고
    • All roads lead to Rome: Pathways of NKT cells promoting asthma
    • Jinquan T, Li W, Yuling H, Lang C: All roads lead to Rome: Pathways of NKT cells promoting asthma. Arch Immunol Ther Exp (2006) 54(5):335-340.
    • (2006) Arch Immunol Ther Exp , vol.54 , Issue.5 , pp. 335-340
    • Jinquan, T.1    Li, W.2    Yuling, H.3    Lang, C.4
  • 52
    • 12444304178 scopus 로고    scopus 로고
    • CD226 expression deficiency causes high sensitivity to apoptosis in NK T cells from patients with systemic lupus erythematosus
    • Tao D, Shangwu L, Qun W, Yan L, Wei J, Junyan L, Feili G, Boquan J, Jinquan T: CD226 expression deficiency causes high sensitivity to apoptosis in NK T cells from patients with systemic lupus erythematosus. J Immunol (2005) 174(3):1281-1290.
    • (2005) J Immunol , vol.174 , Issue.3 , pp. 1281-1290
    • Tao, D.1    Shangwu, L.2    Qun, W.3    Yan, L.4    Wei, J.5    Junyan, L.6    Feili, G.7    Boquan, J.8    Jinquan, T.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.