Implantation of episcleral electrodes via anterior orbitotomy for stimulation of the retina with induced photoreceptor degeneration: An in vivo feasibility study on a conceptual visual prosthesis

Acta Neurochirurgica

Volumn 150, Issue 5, 2008, Pages 477-485

  Siu, T ^a   Morley, J ^a,b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b UNIVERSITY OF WESTERN SYDNEY   (Australia)

Author keywords

Electrical evoked potential; Episcleral stimulation; Photoreceptor disease; Visual prosthesis

Indexed keywords

SODIUM IODATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENERGY; CONTROLLED STUDY; DENSITY; ELECTRODE; ELECTROSTIMULATION; EPISCLERAL ELECTRODE; EVOKED VISUAL RESPONSE; EYE SURGERY; FEASIBILITY STUDY; IMPLANTATION; IN VIVO STUDY; NONHUMAN; ORBIT IMPLANT; ORBITOTOMY; PHOTORECEPTOR; PIGMENTATION; PRIORITY JOURNAL; RABBIT; RETINA; RETINA DEGENERATION; SAFETY; SCLERA; SURGICAL APPROACH; TOPOGRAPHY; VISUAL CORTEX; VISUAL PROSTHESIS; VISUAL STIMULATION;

ANIMALS; ELECTRIC STIMULATION THERAPY; ELECTRODES, IMPLANTED; ELECTRORETINOGRAPHY; EQUIPMENT DESIGN; EVOKED POTENTIALS; FEASIBILITY STUDIES; ORBIT; PHOTORECEPTORS, VERTEBRATE; RABBITS; REACTION TIME; RETINA; RETINAL DEGENERATION; SCLERA; VISUAL CORTEX;

EID: 43549095194     PISSN: 00016268     EISSN: 09420940     Source Type: Journal    
DOI: 10.1007/s00701-008-1528-7     Document Type: Article

References (42)

1. GS Brindley WS Lewin 1968 The sensations produced by electrical stimulation of the visual cortex J Physiol 196 479 493
2. MM Brown GC Brown S Sharma J Kistler H Brown 2001 Utility values associated with blindness in an adult population Br J Ophthalmol 85 327 331
3. SB Brummer MJ Turner 1977 Electrochemical considerations for safe electrical stimulation of the nervous system with platinum electrodes IEEE Trans Biomed Eng 24 59 63
4. AY Chow VY Chow 1997 Subretinal electrical stimulation of the rabbit retina Neurosci Lett 225 13 16
5. WH Dobelle 2000 Artificial vision for the blind by connecting a television camera to the visual cortex Asaio J 46 3 9
6. F Gekeler K Kobuch HN Schwahn A Stett K Shinoda E Zrenner 2004 Subretinal electrical stimulation of the rabbit retina with acutely implanted electrode arrays Graefes Arch Clin Exp Ophthalmol 242 587 596
7. RJ Greenberg 2000 Visual prostheses: a review Neuromodulation 3 161 165
8. L Hesse T Schanze M Wilms M Eger 2000 Implantation of retina stimulation electrodes and recording of electrical stimulation responses in the visual cortex of the cat Graefes Arch Clin Exp Ophthalmol 238 840 845
9. M Humayun Y Sato R Propst E de Juan Jr 1995 Can potentials from the visual cortex be elicited electrically despite severe retinal degeneration and a markedly reduced electroretinogram? Ger J Ophthalmol 4 57 64
10. MS Humayun E de Juan Jr G Dagnelie RJ Greenberg RH Propst DH Phillips 1996 Visual perception elicited by electrical stimulation of retina in blind humans Arch Ophthalmol 114 40 46
11. MS Humayun JD Weiland GY Fujii R Greenberg R Williamson J Little B Mech V Cimmarusti G Van Boemel G Dagnelie E de Juan 2003 Visual perception in a blind subject with a chronic microelectronic retinal prosthesis Vision Res 43 2573 2581
12. DW Hunt P Margaron 2003 Status of therapies in development for the treatment of age-related macular degeneration Drugs 6 464 469
13. L Hyman 1987 Epidemiology of eye disease in the elderly Eye 1 Pt 2 330 341
14. AM Khan MA Varvares 2006 Traditional approaches to the orbit Otolaryngol Clin North Am 39 895 909 vi
15. W Koller R Pahwa K Busenbark J Hubble S Wilkinson A Lang P Tuite E Sime A Lazano R Hauser T Malapira D Smith D Tarsy E Miyawaki T Norregaard T Kormos CW Olanow 1997 High-frequency unilateral thalamic stimulation in the treatment of essential and parkinsonian tremor Ann Neurol 42 292 299
16. L Lamberg 1998 Blind people often sleep poorly; research shines light on therapy JAMA 280 1123 1124 1126
17. R Laszig N Marangos P Sollmann R Ramsden B Fraysse T Lenarz H Rask-Andersen G Bredberg O Sterkers M Manrique B Nevison 1997 Initial results from the clinical trial of the nucleus 21-channel auditory brain stem implant Am J Otol 18 S160
18. O Lindvall Z Kokaia A Martinez-Serrano 2004 Stem cell therapy for human neurodegenerative disorders - how to make it work Nat Med 10 Suppl S42 S50
19. GE Loeb 1990 Cochlear prosthetics Annu Rev Neurosci 13 357 371
20. DM Long 1977 Electrical stimulation for the control of pain Arch Surg 112 884 888
21. E Margalit M Maia JD Weiland RJ Greenberg GY Fujii G Torres DV Piyathaisere TM O'Hearn W Liu G Lazzi G Dagnelie DA Scribner E de Juan Jr MS Humayun 2002 Retinal prosthesis for the blind Surv Ophthalmol 47 335 356
22. MN Nadig 1999 Development of a silicon retinal implant: cortical evoked potentials following focal stimulation of the rabbit retina with light and electricity Clin Neurophysiol 110 1545 1553
23. K Nakauchi T Fujikado H Kanda T Morimoto JS Choi Y Ikuno H Sakaguchi M Kamei M Ohji T Yagi S Nishimura H Sawai Y Fukuda Y Tano 2005 Transretinal electrical stimulation by an intrascleral multichannel electrode array in rabbit eyes Graefes Arch Clin Exp Ophthalmol 243 169 174
24. AM Potts J Inoue 1970 The electrically evoked response of the visual system (EER). 3. Further contribution to the origin of the EER Invest Ophthalmol 9 814 819
25. JF Rizzo 3rd S Goldbaum M Shahin TJ Denison J Wyatt 2004 In vivo electrical stimulation of rabbit retina with a microfabricated array: strategies to maximize responses for prospective assessment of stimulus efficacy and biocompatibility Restor Neurol Neurosci 22 429 443
26. JF Rizzo 3rd J Wyatt J Loewenstein S Kelly D Shire 2003 Perceptual efficacy of electrical stimulation of human retina with a microelectrode array during short-term surgical trials Invest Ophthalmol Vis Sci 44 5362 5369
27. RD Ross 1998 Is perception of light useful to the blind patient? Arch Ophthalmol 116 236 238
28. HG Sachs F Gekeler H Schwahn W Jakob M Kohler F Schulmeyer J Marienhagen U Brunner C Framme 2005 Implantation of stimulation electrodes in the subretinal space to demonstrate cortical responses in Yucatan minipig in the course of visual prosthesis development Eur J Ophthalmol 15 493 499
29. H Sakaguchi T Fujikado X Fang H Kanda M Osanai K Nakauchi Y Ikuno M Kamei T Yagi S Nishimura M Ohji T Yagi Y Tano 2004 Transretinal electrical stimulation with a suprachoroidal multichannel electrode in rabbit eyes Jpn J Ophthalmol 48 256 261
30. T Schanze M Wilms M Eger L Hesse R Eckhorn 2002 Activation zones in cat visual cortex evoked by electrical retina stimulation Graefes Arch Clin Exp Ophthalmol 240 947 954
31. EM Schmidt MJ Bak FT Hambrecht CV Kufta DK O'Rourke P Vallabhanath 1996 Feasibility of a visual prosthesis for the blind based on intracortical microstimulation of the visual cortex Brain 119 Pt 2 507 522
32. HN Schwahn F Gekeler K Kohler K Kobuch HG Sachs F Schulmeyer W Jakob VP Gabel E Zrenner 2001 Studies on the feasibility of a subretinal visual prosthesis: data from Yucatan micropig and rabbit Graefes Arch Clin Exp Ophthalmol 239 961 967
33. JH Seaber R Machemer D Eliott EG Buckley E de Juan DF Martin 1995 Long-term visual results of children after initially successful vitrectomy for stage V retinopathy of prematurity Ophthalmology 102 199 204
34. HA Shah SR Montezuma JF Rizzo 3rd 2006 In vivo electrical stimulation of rabbit retina: effect of stimulus duration and electrical field orientation Exp Eye Res 83 247 254
35. S Suzuki MS Humayun JD Weiland SJ Chen E Margalit DV Piyathaisere E de Juan Jr 2004 Comparison of electrical stimulation thresholds in normal and retinal degenerated mouse retina Jpn J Ophthalmol 48 345 349
36. HR Taylor JE Keeffe HT Vu JJ Wang E Rochtchina ML Pezzullo P Mitchell 2005 Vision loss in Australia Med J Aust 182 565 568
37. JM Thompson CN Woolsey SA Talbot 1950 Visual areas I and II of cerebral cortex of rabbit J Neurophysiol 13 277 288
38. JE Turner JR Blair M Seiler R Aramant TW Laedtke ET Chappell L Clarkson 1988 Retinal transplants and optic nerve bridges: possible strategies for visual recovery as a result of trauma or disease Int Rev Neurobiol 29 281 308
39. P Walter K Heimann 2000 Evoked cortical potentials after electrical stimulation of the inner retina in rabbits Graefes Arch Clin Exp Ophthalmol 238 315 318
40. JD Weiland MS Humayun 2006 Intraocular retinal prosthesis. Big steps to sight restoration IEEE Eng Med Biol Mag 25 60 66
41. Y Yamauchi LM Franco DJ Jackson JF Naber RO Ziv JF Rizzo HJ Kaplan V Enzmann 2005 Comparison of electrically evoked cortical potential thresholds generated with subretinal or suprachoroidal placement of a microelectrode array in the rabbit J Neural Eng 2 S48 S56
42. E Zrenner 2002 Will retinal implants restore vision? Science 295 1022 1025