Implantation of stimulation electrodes in the subretinal space to demonstrate cortical responses in Yucatan minipig in the course of visual prosthesis development

European Journal of Ophthalmology

Volumn 15, Issue 4, 2005, Pages 493-499

  Sachs, H G ^a   Gekeler, F ^b   Schwahn, H ^b   Jakob, W ^a   Kohler M ^a   Schulmeyer, F ^a   Marienhagen, J ^a   Brunner, U ^a   Framme, C ^a  

^a UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^b Div Experimental Ophthalmic Surgery   (Germany)

Author keywords

Animal model; Retinal implant; Visual prosthesis

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ELECTRODE; EVOKED VISUAL RESPONSE; IMPLANTATION; MEASUREMENT; MINIPIG; NONHUMAN; PRIORITY JOURNAL; VISUAL CORTEX; VISUAL NERVOUS SYSTEM; VISUAL PROSTHESIS; ANIMAL; ELECTRIC CONDUCTIVITY; ELECTROSTIMULATION; FEASIBILITY STUDY; FLUORESCENCE ANGIOGRAPHY; MICROELECTRODE; PHOTOSTIMULATION; PHYSIOLOGY; PROSTHESES AND ORTHOSES; RETINA; SWINE; VISION;

BIOMATERIAL;

ANIMALS; BIOCOMPATIBLE MATERIALS; ELECTRIC CONDUCTIVITY; ELECTRIC STIMULATION; ELECTRODES, IMPLANTED; EVOKED POTENTIALS, VISUAL; FEASIBILITY STUDIES; FLUORESCEIN ANGIOGRAPHY; MICROELECTRODES; PHOTIC STIMULATION; PROSTHESES AND IMPLANTS; PROSTHESIS IMPLANTATION; RETINA; SWINE; SWINE, MINIATURE; VISION; VISUAL CORTEX;

EID: 23844461520     PISSN: 11206721     EISSN: None     Source Type: Journal    
DOI: 10.1177/112067210501500413     Document Type: Article

References (19)

1. Chow AY, Peachey N. The subretinal microphotodiode array. Retinal prosthesis II. Ophthalmic Res 1999; 31: 246.
2. Chow AY, Chow VY. Subretinal electrical stimulation of the rabbit retina. Neurosci Lett 1997; 225: 13-6.
3. Chow AY, Peachey NS. The subretinal microphotodiode array. Retinal prosthesis. Ophthalmic Res 1998; 30: 195-6.
4. Guenther E, Tröger B, Schlosshauer B, Zrenner E. Long-term survival of retinal cell cultures on retinal implant materials. Vision Res 1999; 39: 3988-94.
5. Zrenner E, Gabel V-P, Haemmerle H, Hoefflinger B, Schubert M. Reply to the letter of Drs. Chow and Peachey: The subretinal microphotodiode array retinal prosthesis II. Ophthalmic Res 1999; 31: 247.
6. Zrenner E, Miliczek K-D, Gabel V-P, et al. The development of subretinal microphotodiodes for replacement of degenerated photoreceptors. Ophthalmic Res 1997; 29: 269-80.
7. Zrenner E, Gabel V-P, Haemmerle H, Hoefflinger B, Schubert M. Subretinal implants. Ophthalmic Res 1998; 30: 197-8.
8. Kanda H, Yagi T, Ito Y, Tanaka S, Watanabe M, Uchikawa Y. Efficient stimulation inducing neural activity in retinal implant. IEEE 1999; IV: 409-13.
9. Majji AB, Humayun MS, Weiland JD, Suzuki S, D'Anna SA, De Juan E Jr. Long-term histological and electrophysiological results of an inactive epiretinal electrode array implantation in dogs. Invest Ophthalmol Vis Sci 1999; 40: 2073-81.
10. Nadig MN. Development of a silicone retinal implant: cortical evoked potentials following focal stimulation of the rabbit retina with light and electricity. Clin Neurophysiol 1999; 110: 1545-53.
11. Peyman G, Chow AY, Liang C, Chow VY, Perlman JI, Peachey NS. Subretinal semiconductor microphotodiode array. Ophthalmic Surg Lasers 1998; 29: 234-41.
12. Veraart C, Raftopoulos C, Mortimier TJ, et al. Visual sensations produced by optic nerve stimulation using an implanted self-sizing spiral cuff electrode. Brain Res 1998; 813: 181-6.
13. Walter P, Szurman P, Vobig M, et al. Successful long-term implantation of electrically inactive epiretinal microelectrode arrays in rabbits. Retina 1999; 19: 546-52.
14. Humayun MS, de Juan EJ, Dagniele G, Greenberg RJ, Propst RH, Phillips DH. Visual perception elicited by electrical stimulation of retina in blind humans. Arch Ophthalmol 1996; 114: 40-6.
15. Humayun MS, de Juan EJ, Weiland JD, et al. Pattern electrical stimulation of the human retina. Vision Res 1999; 39: 2569-2576.
16. Normann RA, Maynard EM, Rousche PJ, Warren DJ. A neural interface for a cortical vision prosthesis. Vis Res 1999; 39: 2577-87.
17. Dobelle WH, Mladejovsky MG. Phosphenes produced by electrical stimulation of human occipital cortex, and their application to the development of a prosthesis for the blind. J Physiol (Lond) 1974; 243: 553-76.
18. Land MF, Nielsson DE. Animal Eyes. Oxford: Oxford University Press, 2002.
19. Schwahn HN, Gekeler F, Kohler K. Studies on the feasibility of a subretinal visual prosthesis: data from Yucatan micropig and rabbit. Graefes Arch Clin Exp Ophthalmol 2001; 239: 961-7.