Enhanced immunocompetent cells in Chlamydial cervicitis

Journal of Reproductive Medicine for the Obstetrician and Gynecologist

Volumn 49, Issue 8, 2004, Pages 671-677

  Mittal, Aruna ^a   Rastogi, Sangita ^a   Reddy, B S ^a   Verma, Saurabh ^a   Salhan, Sudha ^a   Gupta, Ekta ^a  

^a SAFDARJUNG HOSPITAL   (India)

Author keywords

Cervicitis; Chlamydia trachomatis; Immunocompetence

Indexed keywords

CD19 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; CD83 ANTIGEN; CELL SURFACE MARKER; MONOCLONAL ANTIBODY;

ADULT; ARTICLE; CANDIDA; CELLULAR IMMUNITY; CHLAMYDIA TRACHOMATIS; CLINICAL ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GRAM STAINING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNOCOMPETENT CELL; IMMUNOPHENOTYPING; INDIA; MUCOSAL IMMUNITY; NEISSERIA GONORRHOEAE; PARITY; PREVALENCE; PRIORITY JOURNAL; STATISTICAL ANALYSIS; TRICHOMONAS VAGINALIS; UTERINE CERVICITIS; VAGINA DISCHARGE; VAGINITIS;

ADULT; ANTIGENS, CD; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL COMMUNICATION; CHLAMYDIA INFECTIONS; CHLAMYDIA TRACHOMATIS; DENDRITIC CELLS; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOCOMPETENCE; PHENOTYPE; UTERINE CERVICITIS;

EID: 4344661802     PISSN: 00247758     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Stamm WE, Holmes KK: Chlamydia trachomatis infection of the adult. In Sexually Transmitted Diseases. Edited by KK Holmes, PA Mårdh, PF Sparling. New York, McGraw-Hill, 1990, pp 183-187
2. Brunham RC, Peeling R, Maclean I, et al: Chlamydia trachomatis associated ectopic pregnancy: Serologic and histologic correlates. J Infect Dis 1992;165:1076-1081
3. Olaitan A, Johnson MA, Maclean A, et al: The distribution of immunocompetent cells in genital tract of HIV+ women. AIDS 1996;10:759-764
4. Given AL, White HD, Stern JE, et al: Flow cytometric analysis of leukocytes in human genital tract: Comparision of fallopian tube, uterus, cervix and vagina. Am J Reprod Immunol 1997;38:350-359
5. Kelly KA, Walker JC, Jameel SH, et al: Differential regulation of CD4 lymphocytes recruitment between the upper and lower region of genital tract during Chlamydia trachomatis inection. Infect Immun 2000;68:1519-1528
6. Cain TK, Rank RG: Local Th1-like responses are induced by intravaginal infection of mice with the mouse pneumonitis biovar of Chlamydia trachomatis. Infect Immun 1995;63: 1784-1789
7. Igietseme JU, Ramsey KH, Magee DM, et al: Resolution of murine chlamydial genital infection by the adoptive transfer of a biovar specific Th1 lymphocyte. J Immunol 1993;5:317-324
8. Victoria P, Bhoomker A: Endocervical CD4 lymphocytes among women with non-ulcerative transmitted disease. J Infect Dis 1998;177:167-174
9. Kelly KA, Rank RG: Identification of homing receptors that mediate the recruitment of CD4+T cells to the genital tract following intravaginal infection with Chlamydia trachomatis. Infect Immun 1997;65:5198-5208
10. Kim S-K, Angevine M, Demick K, et al: Induction of HLA Class I-restricted CD8+ CTLs specific for the major outer membrane protein of Chlamydia trachomatis in human genital tract infections. J Immunol 1999;162:6855-6866
11. Magee DM, William DM, Smith JG, et al: Role of CD8+ T cells in primary Chlamydia infection. Infect Immun 1995;63:516-521
12. Igietseme JU, Magee DM, Williams DM, et al: Role for CD8+ T cells in antichlamydial immunity defined by Chlamydia-specific T-lymphocyte clones. Infect Immun 1994;62:5195-5197
13. Kiviat NB, Paavonen J, Walner-Hanssen P, et al: Histopathology of endocervical infection caused by Chlamydia trachomatis, HSV, Trichomonas vaginalis and Neisseria gonorrhoeae. Hum Pathol 1990;21:831-837
14. Prakash M, Patterson S, Kapembwa MS: Macrophages are increased in cervical epithelium of women with cervicitis. Sex Transm Inf 2001;77:366-369
15. Morrison RP, Feilzer K, Tumas DB: Gene knockout mice establish a primary protective role for major histocompatibility complex class II-restricted responses in Chlamydia trachomatis genital tract infection. Infect Immun 1995;33:4661-4668
16. Todd BJ: Clinical utility of measuring WBC on endocervical gram stain for prediction of Chlamydia. Sex Transm Dis 2000;27:530-538
17. Bourke GJ, Dolly EL, McGilvary J: Interpretation and Uses of Medical Statistics. London, Blackwell Scientific Publications, 1985
18. Charu K, Murdin AD, Underdown BG, et al: Chlamydia trachomatis infection in female reproductive tract of rat: Influence of progesterone on infectivity and immune response. Infect Immun 1998;66:893-898
19. White HD, Crassi RM, Given AL, et al: CD3+, CD8+ CTL activity within human female reproductive tract: Influence of stage of menstrual cycle and menopause. J Immunol 1997; 158:3017-3027
20. Hill JA, Anderson DG: Human vaginal leukocytes and the effect of vaginal fluid on lymphocytes and macrophage defense functions. Am J Obstet Gynecol 1992;166:720-726
21. Ramsey KH, Rank RG: Resolution of chlamydial genital infection with antigen specific T-lymphocyte lines. Infect Immun 1991;59:925-931
22. Simen HB, Shergren JN: Immunologically mediated enhancement of macrophage bactericidal capacity. J Exp Med 1971;133:1377-1389
23. Starnbach MN, Bevan MJ, Lampe MF: Protective cytotoxic T-lymphocytes are induced during murine infection with Chlamydia trachomatis. J Immunol 1994;153:5183-5189
24. Su H, Caldwell HD: CD4+ Tcells play a significant role in adoptive immunity to Chlamydia trachomatis infection of mouse genital tract. Infect Immun 1995;63:3302-3308
25. Mittal A, Kapur S, Gupta S: Host immune response in chlamydial cervicitis. Br J Biomed Sci 1996;53:941-947