Significant inhibition by the flavonoid antioxidant silymarin against 12-O-tetradecanoylphorbol 13-acetate-caused modulation of antioxidant and inflammatory enzymes, and cyclooxygenase 2 and interleukin-1α expression in SENCAR mouse epidermis: Implications in the prevention of stage I tumor promotion

Molecular Carcinogenesis

Volumn 26, Issue 4, 1999, Pages 321-333

  Zhao, Jifu ^a   Sharma, Yogesh ^a   Agarwal, Rajesh ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO CANCER CENTER   (United States)

Author keywords

Antioxidants; Chemoprevention; Silymarin; Tumor promotion

Indexed keywords

ACETONE; INTERLEUKIN 1ALPHA; MYELOPEROXIDASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROSTAGLANDIN SYNTHASE; SILYMARIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER PREVENTION; CANCER STAGING; CARCINOGENESIS; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; EPIDERMIS; FEMALE; LIPID PEROXIDATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN EDEMA; TUMOR GROWTH; TUMOR PROMOTION;

ANIMALS; ANTIOXIDANTS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1; ISOENZYMES; LIPID PEROXIDATION; MEMBRANE PROTEINS; MICE; MICE, INBRED SENCAR; MICROSOMES; NEUTROPHILS; PEROXIDASE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SILYMARIN; SKIN; SKIN NEOPLASMS; SUPEROXIDE DISMUTASE; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0032713528     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2744(199912)26:4<321::AID-MC11>3.0.CO;2-9     Document Type: Article

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