Characterization and in vivo study of sustained-release formulation of human growth hormone using sodium hyaluronate

Pharmaceutical Research

Volumn 21, Issue 8, 2004, Pages 1374-1381

  Hahn, Sei Kwang ^a   Kim, Sun Jin ^a   Kim, Myung Jin ^a   Kim, Duk Hee ^b  

^a Biotech Group   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

formulation; human growth hormone; lecithin; sodium hyaluronate; spray drying; sustained release.

Indexed keywords

HYALURONIC ACID; RECOMBINANT GROWTH HORMONE; SOMATOMEDIN C;

ARTICLE; BULK DENSITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISPERSION; DOG; DRUG FORMULARY; DRUG RELEASE; DRUG SCREENING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE RELEASE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; PARTICLE SIZE; PHARMACODYNAMICS; PHYSICAL CHEMISTRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SOLID STATE; STRUCTURE ANALYSIS; SUSTAINED DRUG RELEASE; TECHNIQUE;

ANIMALS; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DELAYED-ACTION PREPARATIONS; DOGS; DRUG COMPOUNDING; DRUG STABILITY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMAN GROWTH HORMONE; HYALURONIC ACID; MALE; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; RECOMBINANT PROTEINS;

EID: 4344604027     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:PHAM.0000036910.41224.de     Document Type: Article

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