Comparative assessment of toxicities of mainstream smoke from commercial cigarettes

Inhalation Toxicology

Volumn 16, Issue 10, 2004, Pages 691-700

  Ritter, Detlef ^a   Knebel, Jan W ^a   Aufderheide, Michaela ^a  

^a FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON MONOXIDE; CIGARETTE SMOKE; GLUTATHIONE;

AEROSOL; ARTICLE; COMPARATIVE STUDY; ENVIRONMENTAL EXPOSURE; HUMAN; HUMAN CELL; IN VITRO STUDY; MONITORING; PARTICULATE MATTER; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SENSITIVITY ANALYSIS; SMOKING;

CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; HUMANS; INHALATION EXPOSURE; PLANTS, TOXIC; PULMONARY ALVEOLI; SMOKE; TARS; TOBACCO;

NICOTIANA TABACUM;

EID: 4344590548     PISSN: 08958378     EISSN: None     Source Type: Journal    
DOI: 10.1080/08958370490476659     Document Type: Article

References (50)

1. Aufderheide, M., and Mohr, U. 1999. CULTEX - A new system and technique for the cultivation and exposure of cells at the air/liquid interface. Exp. Toxicol. Pathol. 51(6):489-490.
2. Aufderheide, M., Knebel, J. W., and Ritter, D. 2003. Novel approaches for studying pulmonary toxicity in vitro. Toxicol. Lett. 140-141:205-211.
3. Bombick, D. W., Ayres, P. H., and Doolittle, D. J. 1997. Cytotoxicity assessment of whole smoke and vapor phase of mainstream and sidestream cigarette smoke from three Kentucky reference cigarettes. Toxicol. Methods 7:179-192.
4. Bombick, B. R., Murli, H., Avalos, J. T., Bombick, D. W., Morgan, W. T., Putnam, K. P., and Doolittle, D. J. 1998a. Chemical and biological studies of a new cigarette that primarily heats tobacco. Part 2. In vitro toxicology of mainstream smoke condensate. Food Chem. Toxicol. 36(3):183-190.
5. Bombick, D. W., Ayres, P. H., Putnam, K., Bombick, B. R., and Doolittle, D. J. 1998b. Chemical and biological studies of a new cigarette that primarily heats tobacco. Part 3. In vitro toxicity of whole smoke. Food Chem. Toxicol. 36(3):191-197.
6. Cantin, A. M., North, S. L., Hubbard, R. C., and Crystal, R. G. 1987. Normal alveolar epithelial lining fluid contains high levels of glutathione. J. Appl. Physiol. 63(1):152-157.
7. Comhair, S. A., and Erzurum, S. C. 2002. Antioxidant responses to oxidant-mediated lung diseases. Am. J. Physiol. Lung Cell Mol. Physiol. 283(2):L246-L255.
8. Dickinson, D. A., Moellering, D. R., Iles, K. E., Patel, R. P., Levonen, A. L., Wigley, A., Darley-Usmar, V. M., and Forman, H. J. 2003. Cytoprotection against oxidative stress and the regulation of glutathione synthesis. Biol. Chem. 384(4):527-537.
9. Djordjevic, M. V., Fan, J., Ferguson, S., and Hoffmann, D. 1995. Self-regulation of smoking intensity. Smoke yields of the low-nicotine, low-"tar" cigarettes. Carcinogenesis 16(9):2015-2021.
10. Djordjevic, M. V., Hoffmann, D., and Hoffmann, I. 1997. Nicotine regulates smoking patterns. Prev. Med. 26(4):435-440.
11. Djordjevic, M. V., Stellman, S. D., and Zang, E. 2000. Doses of nicotine and lung carcinogens delivered to cigarette smokers. JNCI 92(2):106-111.
12. Doolittle, D. J., Lee, C. K., Ivett, J. L., Mirsalis, J. C., Riccio, E., Rudd, C. J., Burger, G. T., and Hayes, A. W. 1990. Comparative studies on the genotoxic activity of mainstream smoke condensate from cigarettes which burn or only heat tobacco. Environ. Mol. Mutagen. 15(2):93-105.
13. Halliwell, B. 1999. Oxygen and nitrogen are pro-carcinogens. Damage to DNA by reactive oxygen, chlorine and nitrogen species: Measurement, mechanism and the effects of nutrition. Mutat. Res. 443(1-2):37-52.
14. Hissin, P. J., and Hilf, R. 1976. A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal. Biochem. 74(1):214-226.
15. Hoffmann, D., and Wynder, E. L. 1986. Chemical constituents and bioactivity of tobacco smoke. IARC Sci. Pub. 74:145-165.
16. Hukkanen, J., Lassila, A., Paivarinta, K., Valanne, S., Sarpo, S., Hakkola, J., Pelkonen, O., and Raunio, H. 2000. Induction and regulation of xenobiotic-metabolizing cytochrome P450s in the human A549 lung adenocarcinoma cell line. Am. J. Respir. Cell Mol. Biol. 22(3):360-366.
17. Ishii, T., Matsuse, T., Teramoto, S., Matsui, H., Miyao, M., Hosoi, T., Takahashi, H., Fukuchi, Y., and Ouchi, Y. 1999. Glutathione S-transferase P1 (GSTP1) polymorphism in patients with chronic obstructive pulmonary disease. Thorax 54(8):693-696.
18. Iwanari, M., Nakajima, M., Kizu, R., Hayakawa, K., and Yokoi, T. 2002. Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: Chemical-, cytochrome P450 isoform-, and cell-specific differences. Arch. Toxicol. 76(5-6):287-298.
19. Lee, C. K., Doolittle, D. J., Burger, G. T., and Hayes, A. W. 1990. Comparative genotoxicity testing of mainstream whole smoke from cigarettes which burn or heat tobacco. Mutat. Res. 242(1):37-45.
20. Li, X. Y., Donaldson, K., Rahman, I., and MacNee, W. 1994. An investigation of the role of glutathione in increased epithelial permeability induced by cigarette smoke in vivo and in vitro. Am. J. Respir. Crit. Care. Med. 149(6):1518-1525.
21. Lieber, M., Smith, B., Szakal, A., Nelson-Rees, W., and Todaro, G. 1976. A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells. Int. J. Cancer 17(1):62-70.
22. Mates, J. M., Perez-Gomez, C., and Nunez de Castro, I. 1999. Antioxidant enzymes and human diseases. Clin. Biochem. 32(8):595-603.
23. McKarns, S. C., Bombick, D. W., Morton, M. J., and Doolittle, D. J. 2000. Gap junction intercellular communication and cytotoxicity in normal human cells after exposure to smoke condensates from cigarettes that burn or primarily heat tobacco. Toxicol. In Vitro 14(1):41-51.
24. Mendelson, C. R., and Boggaram, V. 1991. Hormonal control of the surfactant system in fetal lung. Annu. Rev. Physiol. 53:415-440.
25. Mertens, K., Rogiers, V., Sonck, W., and Vercruysse, A. 1991. Measurement of reduced and oxidized glutathione in cultures of adult rat hepatocytes. J. Chromatogr. 565(1-2):149-157.
26. Miller, M. C. 3rd, Mohrenweiser, H. W., and Bell, D. A. 2001. Genetic variability in susceptibility and response to toxicants. Toxicol. Lett. 120(1-3):269-280.
27. Morrison, D., Rahman, I., Lannan, S., and MacNee, W. 1999. Epithelial permeability, inflammation, and oxidant stress in the air spaces of smokers. Am. J. Respir. Crit. Care Med. 159(2):473-479.
28. Nardone, L. L., and Andrews, S. B. 1979. Cell line A549 as a model of the type II pneumocyte. Phospholipid biosynthesis from native and organometallic precursors. Biochim. Biophys. Acta 573(2):276-295.
29. Park, E. M., Park, Y. M., and Gwak, Y. S. 1998. Oxidative damage in tissues of rats exposed to cigarette smoke. Free Radical Biol. Med. 25(1):79-86.
30. Perera, F. P., Mooney, L. A., Stampfer, M., Phillips, D. H., Bell, D. A., Rundle, A., Cho, S., Tsai, W. Y., Ma, J., Blackwood, A., and Tang, D. 2002. Associations between carcinogen-DNA damage, glutathione S-transferase genotypes, and risk of lung cancer in the prospective Physicians' Health Cohort Study. Carcinogenesis 23(10):1641-1646.
31. Pryor, W. A. 1992. Biological effects of cigarette smoke, wood smoke, and the smoke from plastics: The use of electron spin resonance. Free Radical Biol. Med. 13(6):659-676.
32. Pryor, W. A. 1997. Cigarette smoke radicals and the role of free radicals in chemical carcinogenicity. Environ. Health Perspect. 105(suppl 4):875-882.
33. Rahman, I., and MacNee, W. 1999. Lung glutathione and oxidative stress: Implications in cigarette smoke-induced airway disease. Am. J. Physiol. 277(6 Pt 1):L1067-L1088.
34. Rahman, I., Li, X. Y., Donaldson, K., Harrison, D. J., and MacNee, W. 1995. Glutathione homeostasis in alveolar epithelial cells in vitro and lung in vivo under oxidative stress. Am. J. Physiol. 269(3 Pt 1):L285-L292.
35. Rahman, I., Smith, C. A., Lawson, M. F., Harrison, D. J., and MacNee, W. 1996. Induction of gamma-glutamylcysteine synthetase by cigarette smoke is associated with AP-1 in human alveolar epithelial cells. FEBS Lett. 396(1):21-25.
36. Reed, D. J., Babson, J. R., Beatty, P. W., Brodie, A. E., Ellis, W. W., and Potter, D. W. 1980. High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and related thiols and disulfides. Anal. Biochem. 106(1):55-62.
37. Ritter, D., Knebel, J. W., and Aufderheide, M. 2001. In vitro exposure of isolated cells to native gaseous compounds-Development and validation of an optimized system for human lung cells. Exp. Toxicol. Pathol. 53(5):373-386.
38. Ritter, D., Knebel, J. W., and Aufderheide, M. 2003. Exposure of human lung cells to inhalable substances: A novel test strategy involving clean air exposure periods using whole diluted cigarette mainstream smoke. Inhal. Toxicol. 15(1):67-84.
39. Roemer, E., Tewes, F. J., Meisgen, T. J., Veltel, D. J., and Carmines, E. L. 2002. Evaluation of the potential effects of ingredients added to cigarettes. Part 3: In vitro genotoxicity and cytotoxicity. Food Chem. Toxicol. 40(1):105-111.
40. Scherer, G. 1999. Smoking behaviour and compensation: A review of the literature. Psychopharmacology (Berl.) 145(1):1-20.
41. Smith, B. T. 1977. Cell line A549: A model system for the study of alveolar type II cell function. Am. Rev. Respir. Dis. 115(2):285-293.
42. Smith, C. J., and Hansch, C. 2000. The relative toxicity of compounds in mainstream cigarette smoke condensate. Food Chem. Toxicol. 38(7):637-646.
43. Smith, C. J., Perfetti, T. A., Rumple, M. A., Rodgman, A., and Doolittle, D. J. 2001. "IARC Group 2B carcinogens" reported in cigarette mainstream smoke. Food Chem. Toxicol. 39(2):183-205.
44. Smith, C. J., Perfetti, T. A., Garg, R., and Hansch, C. 2003. IARC carcinogens reported in cigarette mainstream smoke and their calculated log P values. Food Chem. Toxicol. 41(6):807-817.
45. Smith, F. B., Kikkawa, Y., Diglio, C. A., and Dalen, R. C. 1982. Increased saturated phospholipid in cultured cells grown with linoleic acid. In Vitro 18(4):331-338.
46. Uejima, Y., Fukuchi, Y., Nagase, T., Matsuse, T., Yamaoka, M., Tabata, R., and Orimo, H. 1990. Influences of inhaled tobacco smoke on the senescence accelerated mouse (SAM). Eur. Respir. J. 3(9):1029-1036.
47. Urani, C., Doldi, M., Crippa, S., and Camatini, M. 1998. Human-derived cell lines to study xenobiotic metabolism. Chemosphere 37(14-15):2785-2795.
48. van Zandwijk, N. 1995. N-Acetylcysteine (NAC) and glutathione (GSH): Antioxidant and chemopreventive properties, with special reference to lung cancer. J. Cell Biochem. Suppl. 22:24-32.
49. Yoshida, T. 1996. Determination of reduced and oxidized glutathione in erythrocytes by high-performance liquid chromatography with ultraviolet absorbance detection. J. Chromatogr. B Biomed. Appl. 678(2):157-64.
50. Young, P. P., and Mendelson, C. R. 1997. A GT box element is essential for basal and cyclic adenosine 3′,5′-monophosphate regulation of the human surfactant protein A2 gene in alveolar type II cells: Evidence for the binding of lung nuclear factors distinct from Sp1. Mol. Endocrinol. 11(8):1082-1093.