Differential effects of interferon-γ on production of trypanosome-derived lymphocyte-triggering factor by Trypanosoma brucei gambiense and Trypanosoma brucei brucei

Journal of Parasitology

Volumn 90, Issue 4, 2004, Pages 740-745

  Nishimura, Kazuhiko ^a   Hamashita, Kanako ^a   Okamoto, Yasuyuki ^a   Kawahara, Fumiya ^a   Ihara, Hideshi ^a   Kozaki, Shunji ^a   Ohnishi, Yoshihiro ^a   Yamasaki, Shinji ^a  

^a Osaka Prefecture University   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MESSENGER RNA; PROTOZOAL PROTEIN; RECOMBINANT GAMMA INTERFERON; TRYPANOSOME DERIVED LYMPHOCYTE TRIGGERING FACTOR; UNCLASSIFIED DRUG;

PARASITOLOGY;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; LYMPHOCYTE; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; SPLEEN CELL; STRAIN DIFFERENCE; TRYPANOSOMA BRUCEI; TRYPANOSOMA GAMBIENSE; TRYPANOSOMIASIS;

ANIMALS; GENE EXPRESSION; INTERFERON TYPE II; MALE; PROTOZOAN PROTEINS; RATS; RATS, WISTAR; RNA, MESSENGER; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMA BRUCEI GAMBIENSE;

ANIMALIA; PROTOZOA; TRYPANOSOMA; TRYPANOSOMA BRUCEI; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMA BRUCEI GAMBIENSE;

EID: 4344573001     PISSN: 00223395     EISSN: None     Source Type: Journal    
DOI: 10.1645/GE-211R1     Document Type: Article

References (31)

1. AYUB, D., S. MAARTEN, H. HUBERTINE, B. LEA, AND DE B. PATRICK. 1993. Inhibition of T-cell responsiveness during experimental infections with Trypanosoma brucei; active involvement of endogenous gamma interferon. Infection and Immunity 61: 3098-3102.
2. BAETSELIER, P. DE, B. NAMANGALA, W. NOEL, L. BRYS, E. PAYS, AND A. BESCHIN. 2001. Alternative versus classical macrophage activation during experimental African trypanosomiasis. International Journal for Parasitology 31: 575-587.
3. BAKHIET, M., P. BUSCHER, R. A. HARRIS, K. KRISTENSSON, H. WIGZELL, AND T. OLSSON. 1996a. Different trypanozoan species possess CD8 dependent lymphocyte triggering factor-like activity. Immunology Letters 50: 71-80.
4. + lymphocytes to interferon-gamma secretion: Purification, characterization and protective effects in vivo by treatment with a monoclonal antibody against the factor. Scandinavian Journal of Immunology 37: 165-178.
5. + T-cells; a trypanosome-released factor triggers interferon-γ production that stimulates parasite growth. European Journal of Immunology 21: 2447-2454.
6. -, -, A. LJUNGDAHL, B. HOJEBERG, P. VAN DER MEIDE, AND K. KRISTENSSON. 1996b. Induction of interferon-gamma, transforming growth factor-beta, and interleukin-4 in mouse strains with different susceptibilities to Trypanosoma brucei brucei. Journal of Interferon & Cytokine Research 16: 427-433.
7. -, -, J. MHLANGA, P. BUSCHER, N. LYCKE, P. H. VAN DER MEIDE, AND K. KRISTENSSON. 1996c. Human and rodent interferon-gamma as a growth factor for Trypanosoma brucei. European Journal of Immunology 26: 1359-1364.
8. + T cells suppresses growth of Trypanosoma brucei brucei and interferon-gamma production in infected rats. Clinical and Experimental Immunology 81: 195-199.
9. -, T. VAIDYA, K. L. HILL, O. TOMAS, K. KRISTER, AND J. E. DONELSON. 1997. The gene for a T lymphocyte triggering factor from African trypanosomes. The Journal of Experimental Medicine 186: 433-438.
10. BANCROFT, G. J., C. J. SUTTON, A. G. MORRIS, AND B. A. ASKONAS. 1983. Production of interferons during experimental African trypanosomiasis. Clinical and Experimental Immunology 52: 135-43.
11. HAMADIEN, M., M. BAKHIET, AND R. A. HARRIS. 2000. Interferon-γ induces secretion of trypanosoma lymphocyte triggering factor via tyrosine protein kinases. Parasitology 120: 281-287.
12. -, -, AND N. LYCKE, 1999. Induction of the trypanosome lymphocyte-triggering factor (TLTF) and neutralizing antibodies to the TLTF in experimental African trypanosomiasis. Immunology 96: 606-611.
13. HANNAERT, V., F. R. OPPERDOES, AND P. A. M. MICHELS. 1998. Comparison and evolutionary analysis of the glycosomal glyceraldehyde-3-phosphate dehydrogenase from different Kinetoplastida. Journal of Molecular Evolution 47: 728-738.
14. HERTZ, C. J., AND J. M. MANSFIELD. 1998. Resistance to the African trypanosomes is IFN-γ dependent. Journal of Immunology 161: 6776-6783.
15. -, AND -. 1999. IFN-γ-dependent nitric oxide production is not linked to resistance in experimental African trypanosomiasis. Cellular Immunology 192: 24-32.
16. HILL, K. L., N. R. HUTCHINGS, D. G. RUSSELL, AND J. E. DONELSON. 1999. A novel protein-targeting domain directs proteins to the anterior cytoplasmic face of the flagellar pocket in African trypanosomes. Journal of Cell Science 112: 3091-3101.
17. LANHAM, S. M. 1968. Separation of trypanosomes from the blood of infection rats and mice by anion-exchangers. Nature 218: 1273-1274.
18. LIU, Y., E. RAGAA, Z. LI, L. NUORTIO, A. MUSTAFA, AND M. BAKHIET. 1999. Interferon-gamma and interleukin-12 genes are preferentially expressed during early experimental African trypanosomiasis and suppressed by denervation of the spleen. Scandinavian Journal of Immunology 50: 485-91.
19. MABBOTT, N. A., I. A. SUTHERLAND, AND J. M. STERNBERG. 1995. Suppressor macrophages in Trypanosoma brucei infection; nitric oxide is related to both suppressive activity and lifespan in vivo. Parasite Immunology 17: 143-150.
20. MUSTAFA, E., M. BAKHIET, R. JASTER, T. BITTORF, E. MIX, AND T. OLSSON. 1997. Tyrosine kinases are required for inteferon-γ stimulated proliferation of Trypanosoma brucei brucei. The Journal of Infectious Diseases 175: 669-673.
21. NAMANGALA, B., W. NOEL, P. DE BAETSELIER, L. BRYS, AND A. BESHIN. 2001. Relative contribution of interferon-γ and interleukin-10 to resistance to murine African trypanosomiasis. The Journal of Infectious Diseases 183: 1794-1800.
22. NISHIMURA, K., N. ARAKI, Y. OHNISHI, AND S. KOZAKI. 2001. Effects of dietary polyamine deficiency on Trypanosoma gambiense infection in rats. Experimental Parasitology 97: 95-101.
23. SILEGHEM, M., A. DARJI, AND P. DE BAETSELIER. 1991. In vitro simulation of immunosuppression caused by Trypanosoma brucei. Immunology 73: 246-248.
24. STERNBERG, J. M. 1998. Immunobiology of African trypanosomiasis. Chemical Immunology 70: 186-998.
25. -, AND A. MABBOTT. 1996. Nitric oxide-mediated suppression of T cell responses during Trypanosoma brucei infection; soluble trypanosome products and interferon-γ are synergistic inducers of nitric oxide synthase. European Journal of Immunology 26: 539-543.
26. TABEL, H., R. S., KAUSHIK, AND J. UZONNA. 1999. Experimental African trypanosomiasis; differences in cytokine and nitric oxide production by macrophages from resistant and susceptible mice. Pathobiology 67: 273-276.
27. TSO, J. Y., X. H. SUN, T. H. KAO, K. S. REECE, AND R. WU. 1985. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: Genomic complexity and molecular evolution of the gene. Nucleic Acids Research 13: 2485-2502.
28. UZONNA, J. E., R. S. KAUSHIK, J. R., GORDON, AND H. TABEL. 1998a. Experimental murine Trypanosoma congolense infections. I. Administration of anti-IFN-γ antibodies alters trypanosome-susceptible mice to a resistant-like phenotype. Journal of Immunology 161: 5507-5515.
29. -, -, -, AND -. 1998b. Immunoregulation in experimental murine Trypanosoma congolense infection; antibodies reverse trypanosome-mediated suppression of lymphocyte proliferations in vitro and moderately prolong the lifespan of genetically susceptible Balb/c mice. Parasite Immunology 20: 297-302.
30. VISSE, E., P. SIESJO, B. WIDEGREN, AND H. O. SJOGREN. 1999. Regression of intracerebral rat glioma isografts by therapeutic subcutaneous immunization with interferon-gamma, interleukin-7, or B7-1-transfected tumor cell. Cancer Gene Therapy 6: 37-44.
31. YABU, Y., T. KOIDE, N. OHTA, M. NOSE, AND Y. OGIHARA. 1998. Continuous growth of bloodstream forms of Trypanosoma brucei in an axenic culture system containing a low concentration of serum. Southeast Asian Journal of Tropical Medicine and Public Health 223: 591-595.