Na+H+ exchanger-1 inhibitors reduce neuronal excitability and alter Na+ channel inactivation properties in rat primary sensory neurons

Toxicological Sciences

Volumn 103, Issue 2, 2008, Pages 346-353

  Liu, Chang Ning ^a   Somps, Chris J ^a  

^a PFIZER INC   (United States)

Author keywords

Dorsal root; Dorsal root ganglion; NHE 1 inhibitor; Patch clamp; Sodium current; Zoniporide

Indexed keywords

CP 628319; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; SODIUM ION; SODIUM PROTON EXCHANGE PROTEIN 1; ZONIPORIDE;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CHANNEL GATING; CONTROLLED STUDY; DISEASE ASSOCIATION; DOG; DRUG STRUCTURE; HYPERPOLARIZATION; MALE; NERVE CELL EXCITABILITY; NERVE ROOT; NEUROTOXICITY; NONHUMAN; PATCH CLAMP; PERIPHERAL NEUROPATHY; RAT; SCIATIC NERVE; SENSORY NERVE CELL; SODIUM CURRENT; SPINAL GANGLION; VENTRAL ROOT;

ACTION POTENTIALS; ANIMALS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GANGLIA, SPINAL; GUANIDINES; ION CHANNEL GATING; MALE; MEMBRANE POTENTIALS; NEURAL CONDUCTION; NEURONS, AFFERENT; PATCH-CLAMP TECHNIQUES; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; SODIUM-HYDROGEN ANTIPORTER;

CANIS FAMILIARIS; RATTUS;

EID: 43349104888     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn045     Document Type: Article

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