Nortriptyline hydrochloride skin absorption: Development of a transdermal patch

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 69, Issue 2, 2008, Pages 588-596

  Melero, Ana ^a,b   Garrigues, T M ^a   Almudever, P ^a   Villodre, A Martín ^a   Lehr, C M ^b   Schafer U ^b  

^a UNIVERSITY OF VALENCIA   (Spain)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Chemical enhancers; Nortriptyline; Percutaneous absorption; Skin; TDS

Indexed keywords

ALCOHOL; HYDROXYPROPYLMETHYLCELLULOSE; LACTIC ACID; NORTRIPTYLINE; OLEIC ACID; POLYSORBATE 80; PROPYLENE GLYCOL;

ADULT; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG RELEASE; EPIDERMIS; FEMALE; HUMAN; HUMAN TISSUE; PH; SKIN ABSORPTION; SKIN PERMEABILITY; TRANSDERMAL PATCH;

ADMINISTRATION, CUTANEOUS; ALGORITHMS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BUFFERS; CHEMISTRY, PHARMACEUTICAL; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIFFUSION CHAMBERS, CULTURE; HUMANS; HYDROGEN-ION CONCENTRATION; LIPIDS; METHYLCELLULOSE; NORTRIPTYLINE; SKIN ABSORPTION; SOLUBILITY; SOLVENTS; THERMODYNAMICS;

EID: 43249125797     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2007.11.012     Document Type: Article

References (31)

1. Hughes J.R. Mechanism of action of a decision aid for smoking cessation treatment. Addiction 101 9 (2006) 1362 (author reply 1362-3)
2. Stimmel G.L. Benzodiazepines in schizophrenia. Pharmacotherapy 16 6 Pt 2 (1996) 148S-151S (discussion 166S-168S)
3. Wagner H., Kostka K.H., Lehr C.M., and Schaefer U.F. Correlation between stratum corneum/water-partition coefficient and amounts of flufenamic acid penetrated into the stratum corneum. J. Pharm. Sci. 91 8 (2002) 1915-1921
4. Amnuaikit C., Ikeuchi I., Ogawara K.-I., Higaki K., and Kimura T. Skin permeation of propranolol from polymeric film containing terpene enhancers for transdermal use. Int. J. Pharm. 289 1-2 (2005) 167-178
5. Williams A.C., and Barry B.W. Penetration enhancers. Adv. Drug Deliv. Rev. 56 5 (2004) 603-618
6. Aboofazeli R., Zia H., and Needham T.E. Transdermal delivery of nicardipine: an approach to in vitro permeation enhancement. Drug Deliv. 9 4 (2002) 239-247
7. Hood H.L., Kraeling M.E., Robl M.G., and Bronaugh R.L. The effects of an alpha hydroxy acid (glycolic acid) on hairless guinea pig skin permeability. Food Chem. Toxicol. 37 11 (1999) 1105-1111
8. Cappel M.J., and Kreuter J. Effect of nonionic surfactants on transdermal drug delivery: I. Polysorbates. Int. J. Pharm. 69 2 (1991) 143-153
9. Venkatraman S., and Gale R. Skin adhesives and skin adhesion. 1. Transdermal drug delivery systems. Biomaterials 19 13 (1998) 1119-1136
10. Diez Sales O., Lopez Castellano A., Maiques Lacer F.J., and Herraez Dominguez M. An in vitro percutaneous absorption study of non-ionic compounds across human skin. Pharmazie 48 9 (1993) 684-686
11. Thomas N.S., and Panchagnula R. Transdermal delivery of zidovudine: effect of vehicles on permeation across rat skin and their mechanism of action. Eur. J. Pharm. Sci. 18 1 (2003) 71-79
12. Wagner H., Kostka K.H., Lehr C.M., and Schaefer U.F. pH profiles in human skin: influence of two in vitro test systems for drug delivery testing. Eur. J. Pharm. Biopharm. 55 1 (2003) 57-65
13. Diez-Sales O., Garrigues T.M., Herraez J.V., Belda R., Martin-Villodre A., and Herraez M. In vitro percutaneous penetration of acyclovir from solvent systems and Carbopol 971-P hydrogels: influence of propylene glycol. J. Pharm. Sci. 94 5 (2005) 1039-1047
14. Williams A.C., and Barry B.W. Terpenes and the lipid-protein-partitioning theory of skin penetration enhancement. Pharm. Res. 8 1 (1991) 17-24
15. Okamoto H., Komatsu H., Hashida M., and Sezaki H. Effects of [beta]-cyclodextrin and di-O-methyl-[beta]-cyclodextrin on the percutaneous absorption of butylparaben, indomethacin and sulfanilic acid. Int. J. Pharm. 30 1 (1986) 35-45
16. Padula C., Nicoli S., Colombo P., and Santi P. Single-layer transdermal film containing lidocaine: modulation of drug release. Eur. J. Pharm. Biopharm. 66 3 (2007) 422-428
17. Siepmann J., and Peppas N.A. Modeling of drug release from delivery systems based on (hydroxypropyl) methyl cellulose (HPMC). Adv. Drug Deliv. Rev. Math. Model. Control. Drug Deliv. 48 2-3 (2001) 139-157
18. Sznitowska M., and Berner B. Polar pathway for percutaneous absorption. Curr. Probl. Dermatol. 22 (1995) 164-170
19. Nicoli S., Penna E., Padula C., Colombo P., and Santi P. New transdermal bioadhesive film containing oxybutynin: in vitro permeation across rabbit ear skin. Int. J. Pharm. 325 1-2 (2006) 2-7
20. Sarveiya V., Templeton J.F., and Benson H.A.E. Effect of lipophilic counter-ions on membrane diffusion of benzydamine. Eur. J. Pharm. Sci. 26 1 (2005) 39-46
21. Bronaugh R.L., Congdon E.R., and Scheuplein R.J. The effect of cosmetic vehicles on the penetration of N-nitrosodiethanolamine through excised human skin. J. Invest. Dermatol. 76 2 (1981) 94-96
22. Yamane M.A., Williams A.C., and Barry B.W. Terpene penetration enhancers in propylene glycol/water co-solvent systems: effectiveness and mechanism of action. J. Pharm. Pharmacol. 47 12A (1995) 978-989
23. Hadgraft J. Passive enhancement strategies in topical and transdermal drug delivery. Int. J. Pharm. 184 1 (1999) 1-6
24. Gao S., and Singh J. Effect of oleic acid/ethanol and oleic acid/propylene glycol on the in vitro percutaneous absorption of 5-fluorouracil and tamoxifen and the macroscopic barrier property of porcine epidermis. Int. J. Pharm. 165 1 (1998) 45-55
25. Panchagnula R., Salve P.S., Thomas N.S., Jain A.K., and Ramarao P. Transdermal delivery of naloxone: effect of water, propylene glycol, ethanol and their binary combinations on permeation through rat skin. Int. J. Pharm. 219 1-2 (2001) 95-105
26. Ongpipattanakul B., Burnette R.R., Potts R.O., and Francoeur M.L. Evidence that oleic acid exists in a separate phase within stratum corneum lipids. Pharm. Res. 8 3 (1991) 350-354
27. Nokhodchi A., Shokri J., Dashbolaghi A., Hassan-Zadeh D., Ghafourian T., and Barzegar-Jalali M. The enhancement effect of surfactants on the penetration of lorazepam through rat skin. Int. J. Pharm. 250 2 (2003) 359-369
28. Shokri J., Nokhodchi A., Dashbolaghi A., Hassan-Zadeh D., Ghafourian T., and Barzegar Jalali M. The effect of surfactants on the skin penetration of diazepam. Int. J. Pharm. 228 1-2 (2001) 99-107
29. Yu D., Sanders L.M., Davidson III G.W., Marvin M.J., and Ling T. Percutaneous absorption of nicardipine and ketorolac in rhesus monkeys. Pharm. Res. 5 7 (1988) 457-462
30. Wagena E.J., Knipschild P.G., Huibers M.J., Wouters E.F., and van Schayck C.P. Efficacy of bupropion and nortriptyline for smoking cessation among people at risk for or with chronic obstructive pulmonary disease. Arch. Intern. Med. 165 19 (2005) 2286-2292
31. J. Hughes, L. Stead, T. Lancaster, Antidepressants for smoking cessation. Cochrane Database Syst. Rev. (4) (2004) CD000031.