Nonhelical leash and α-helical structures determine the potency of a peptide antagonist of human T-cell leukemia virus entry

Journal of Virology

Volumn 82, Issue 10, 2008, Pages 4965-4973

  Mirsaliotis, Antonis ^a   Lamb, Daniel ^a   Brighty, David W ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTIVIRUS AGENT; PEPTIDE 400L A; PEPTIDE PCR 400; PEPTIDE PCR 435; PEPTIDE PCR CC AA; PEPTIDE PCR DELTA C; PEPTIDE PCR DELTA N; PEPTIDE PCR I405A; PEPTIDE PCR I412A; PEPTIDE PCR L403A; PEPTIDE PCR L413A; PEPTIDE PCR L419A; PEPTIDE PCR L424A; PEPTIDE PCR L429A; PROTEIN PATK 400; PEPTIDE; VIRUS FUSION PROTEIN;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG TARGETING; FEMALE; HUMAN; HUMAN CELL; HUMAN T CELL LEUKEMIA VIRUS; HYDROPHOBICITY; IC 50; MEMBRANE FUSION; MEMBRANE POTENTIAL; PRIORITY JOURNAL; VIRUS ENTRY; VIRUS ENVELOPE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; GENE DELETION; GIANT CELL; GROWTH, DEVELOPMENT AND AGING; HUMAN T CELL LEUKEMIA VIRUS 1; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; SYNTHESIS; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN T-LYMPHOTROPIC VIRUS 1;

AMINO ACID SUBSTITUTION; ANTIVIRAL AGENTS; CELL LINE; GIANT CELLS; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; MODELS, MOLECULAR; PEPTIDES; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; SEQUENCE DELETION; VIRAL FUSION PROTEINS; VIRUS INTERNALIZATION;

EID: 43249108698     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02458-07     Document Type: Article

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