Plasma and vitreous homocysteine concentrations in patients with proliferative diabetic retinopathy

Retina

Volumn 28, Issue 5, 2008, Pages 741-743

  Aydemir, Orhan ^a   Türkçüoǧlu, Peykan ^a   Güler, Mete ^a   Çeliker, Ülkü ^a   Üstündaǧ, Bilal ^a   Yilmaz, Turgut ^a   Metin, Kerem ^a  

^a FIRAT UNIVERSITY   (Turkey)

Author keywords

Concentration; Homocysteine; Plasma; Type 2 diabetes mellitus; Vitreous

Indexed keywords

HOMOCYSTEINE;

ADULT; AGED; AMINO ACID BLOOD LEVEL; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETIC RETINOPATHY; EYE DISEASE; EYE SURGERY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; PROLIFERATIVE RETINOPATHY; VITREOUS BODY;

AGED; AGED, 80 AND OVER; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; FEMALE; HOMOCYSTEINE; HUMANS; LASER COAGULATION; MALE; MIDDLE AGED; VITRECTOMY; VITREOUS BODY;

EID: 43249105365     PISSN: 0275004X     EISSN: None     Source Type: Journal    
DOI: 10.1097/IAE.0b013e31816079fb     Document Type: Article

References (18)

1. Boushey CJ, Beresford SA, Omenn GS, Motulsky AG. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA 1995;274:1049-1057.
2. Hoogeveen EK, Kostense PJ, Beks PJ, et al. Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease, especially in non-insulin-dependent diabetes mellitus: a population-based study. Arterioscler Thromb Vasc Biol 1998;18:133-138.
3. Chico A, Perez A, Cordoba A, et al. Plasma homocysteine is related to albumin excretion rate in patients with diabetes mellitus: a new link between diabetic nephropathy and cardiovascular disease? Diabetologia 1998;41:684-693.
4. Buysschaert M, Dramais AS, Wallemacq PE, et al. Hyperhomocysteinemia in type 2 diabetes: relationship to macroangiopathy, nephropathy, and insulin resistance. Diabetes Care 2000;23:1816-1822.
5. Looker HC, Fagot-Campagna A, Gunter EW, et al. Homocysteine as a risk factor for nephropathy and retinopathy in type 2 diabetes. Diabetologia 2003;46:766-772.
6. Hoogeveen EK, Kostense PJ, Eysink PE, et al. Hyperhomocysteinemia is associated with the presence of retinopathy in type 2 diabetes mellitus: the Hoorn study. Arch Intern Med 2000;160:2984-2990.
7. Vaccaro O, Perna AF, Mancini FP, et al. Plasma homocysteine and its determinants in diabetic retinopathy. Diabetes Care 2000;23:1026-1027.
8. Vaccaro O, Perna AF, Mancini FP, et al. Plasma homocysteine and microvascular complications in type 1 diabetes. Nutr Metab Cardiovasc Dis 2000;10:297-304.
9. Gupta A, Robinson K. Hyperhomocysteinaemia and end stage renal disease. J Nephrol 1997;10:77-84.
10. Ndrepepa G, Kastrati A, Braun, et al. Circulating homocysteine levels in patients with type 2 diabetes mellitus. Nutr Metab Cardiovasc Dis 2008;18:66-73.
11. Tyagi SC, Lominadze D, Roberts AM. Homocysteine in microvascular endothelial cell barrier permeability. Cell Biochem Biophys 2005;43:37-44.
12. Wang H, Yoshizumi M, Lai K, et al. Inhibition of growth and p21ras methylation in vascular endothelial cells by homocysteine but not cysteine. J Biol Chem 1997;272:25380-25385.
13. Lentz SR, Sobey CG, Piegors DJ, et al. Vascular dysfunction in monkeys with diet-induced hyperhomocyst(e)inemia. J Clin Invest 1996;98:24-29.
14. Loscalzo J. The oxidant stress of hyperhomocyst13(e)inemia. J Clin Invest 1996;98:5-7.
15. Axer-Siegel R, Bourla D, Ehrlich R, et al. Association of neovascular age-related macular degeneration and hyperhomocysteinemia. Am J Ophthalmol 2004;137:84-89.
16. Kamburoglu G, Gumus K, Kadayifcilar S, et al. Plasma homocysteine, vitamin B12 and folate levels in age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol 2006;244:565-569.
17. Roybal CN, Yang S, Sun CW, et al. Homocysteine increases the expression of vascular endothelial growth factor by a mechanism involving endoplasmic reticulum stress and transcription factor ATF4. J Biol Chem 2004;279:14844- 14852.
18. Lee I, Lee H, Kim JM, et al. Short-term hyperhomocysteinemia-induced oxidative stress activates retinal glial cells and increases vascular endothelial growth factor expression in rat retina. Biosci Biotechnol Biochem 2007;71:1203-1210.