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Volumn 19, Issue 6, 2008, Pages 829-837

Large-scale association study between two coding LRP5 gene polymorphisms and bone phenotypes and fractures in men

Author keywords

BMD; Fracture risk; LRP5; Polymorphism; Population based

Indexed keywords

ALANINE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; METHIONINE; VALINE;

EID: 43249101676     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-007-0512-z     Document Type: Article
Times cited : (25)

References (29)
  • 1
    • 18044386744 scopus 로고    scopus 로고
    • LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
    • Gong Y, Slee RB, Fukai N et al (2001) LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 107:513-523
    • (2001) Cell , vol.107 , pp. 513-523
    • Gong, Y.1    Slee, R.B.2    Fukai, N.3
  • 2
    • 0037373341 scopus 로고    scopus 로고
    • Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) fsgene in different conditions with an increased bone density
    • Van Wesenbeeck L, Cleiren E, Gram J et al (2003) Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) fsgene in different conditions with an increased bone density. Am J Hum Genet 72:763-771
    • (2003) Am J Hum Genet , vol.72 , pp. 763-771
    • Van Wesenbeeck, L.1    Cleiren, E.2    Gram, J.3
  • 3
    • 0037118285 scopus 로고    scopus 로고
    • High bone density due to a mutation in LDL-receptor-related protein 5
    • Boyden LM, Mao J, Belsky J et al (2002) High bone density due to a mutation in LDL-receptor-related protein 5. N Engl J Med 346:1513-1521
    • (2002) N Engl J Med , vol.346 , pp. 1513-1521
    • Boyden, L.M.1    Mao, J.2    Belsky, J.3
  • 4
    • 0036138175 scopus 로고    scopus 로고
    • A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait
    • Little RD, Carulli JP, Del Mastro RG et al (2002) A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait. Am J Hum Genet 70:11-19
    • (2002) Am J Hum Genet , vol.70 , pp. 11-19
    • Little, R.D.1    Carulli, J.P.2    Del Mastro, R.G.3
  • 5
    • 0024239111 scopus 로고
    • Bone mass is low in relatives of osteoporotic patients
    • Evans RA, Marel GM, Lancaster EK et al (1988) Bone mass is low in relatives of osteoporotic patients. Ann Intern Med 109:870-873
    • (1988) Ann Intern Med , vol.109 , pp. 870-873
    • Evans, R.A.1    Marel, G.M.2    Lancaster, E.K.3
  • 6
    • 0023508467 scopus 로고
    • Genetic determinants of bone mass in adults. a twin study
    • Pocock NA, Eisman JA, Hopper JL et al (1987) Genetic determinants of bone mass in adults. A twin study. J Clin Invest 80:706-710
    • (1987) J Clin Invest , vol.80 , pp. 706-710
    • Pocock, N.A.1    Eisman, J.A.2    Hopper, J.L.3
  • 7
    • 0025812532 scopus 로고
    • Genetic determinants of bone mass in adult women: A reevaluation of the twin model and the potential importance of gene interaction on heritability estimates
    • Slemenda CW, Christian JC, Williams CJ et al (1991) Genetic determinants of bone mass in adult women: a reevaluation of the twin model and the potential importance of gene interaction on heritability estimates. J Bone Miner Res 6:561-567
    • (1991) J Bone Miner Res , vol.6 , pp. 561-567
    • Slemenda, C.W.1    Christian, J.C.2    Williams, C.J.3
  • 8
    • 7244234185 scopus 로고    scopus 로고
    • Differential genetic effects of ESR1 gene polymorphisms on osteoporosis outcomes
    • Ioannidis JP, Ralston SH, Bennett ST et al (2004) Differential genetic effects of ESR1 gene polymorphisms on osteoporosis outcomes. Jama 292:2105-2114
    • (2004) Jama , vol.292 , pp. 2105-2114
    • Ioannidis, J.P.1    Ralston, S.H.2    Bennett, S.T.3
  • 9
    • 33646248070 scopus 로고    scopus 로고
    • Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: The GENOMOS study
    • Ralston SH, Uitterlinden AG, Brandi ML et al (2006) Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study. PLoS Med 3:e90
    • (2006) PLoS Med , vol.3
    • Ralston, S.H.1    Uitterlinden, A.G.2    Brandi, M.L.3
  • 10
    • 33747115419 scopus 로고    scopus 로고
    • The association between common vitamin D receptor gene variations and osteoporosis: A participant-level meta-analysis
    • Uitterlinden AG, Ralston SH, Brandi ML et al (2006) The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis. Ann Intern Med 145:255-264
    • (2006) Ann Intern Med , vol.145 , pp. 255-264
    • Uitterlinden, A.G.1    Ralston, S.H.2    Brandi, M.L.3
  • 11
    • 0035179971 scopus 로고    scopus 로고
    • Replication validity of genetic association studies
    • Ioannidis JP, Ntzani EE, Trikalinos TA et al (2001) Replication validity of genetic association studies. Nat Genet 29:306-309
    • (2001) Nat Genet , vol.29 , pp. 306-309
    • Ioannidis, J.P.1    Ntzani, E.E.2    Trikalinos, T.A.3
  • 12
    • 0037442235 scopus 로고    scopus 로고
    • Genetic associations in large versus small studies: An empirical assessment
    • Ioannidis JP, Trikalinos TA, Ntzani EE et al (2003) Genetic associations in large versus small studies: an empirical assessment. Lancet 361:567-571
    • (2003) Lancet , vol.361 , pp. 567-571
    • Ioannidis, J.P.1    Trikalinos, T.A.2    Ntzani, E.E.3
  • 13
    • 2342529785 scopus 로고    scopus 로고
    • Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with variation in vertebral bone mass, vertebral bone size, and stature in whites
    • Ferrari SL, Deutsch S, Choudhury U et al (2004) Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with variation in vertebral bone mass, vertebral bone size, and stature in whites. Am J Hum Genet 74:866-875
    • (2004) Am J Hum Genet , vol.74 , pp. 866-875
    • Ferrari, S.L.1    Deutsch, S.2    Choudhury, U.3
  • 14
    • 0037648420 scopus 로고    scopus 로고
    • Haplotype structure, LD blocks, and uneven recombination within the LRP5 gene
    • Twells RC, Mein CA, Phillips MS et al (2003) Haplotype structure, LD blocks, and uneven recombination within the LRP5 gene. Genome Res 13:845-855
    • (2003) Genome Res , vol.13 , pp. 845-855
    • Twells, R.C.1    Mein, C.A.2    Phillips, M.S.3
  • 15
    • 14844298409 scopus 로고    scopus 로고
    • Influence of LRP5 polymorphisms on normal variation in BMD
    • Koay MA, Woon PY, Zhang Y et al (2004) Influence of LRP5 polymorphisms on normal variation in BMD. J Bone Miner Res 19:1619-1627
    • (2004) J Bone Miner Res , vol.19 , pp. 1619-1627
    • Koay, M.A.1    Woon, P.Y.2    Zhang, Y.3
  • 16
    • 29644446220 scopus 로고    scopus 로고
    • Common genetic variation of the low-density lipoprotein receptor-related protein 5 and 6 genes determines fracture risk in elderly white men
    • van Meurs JB, Rivadeneira F, Jhamai M et al (2006) Common genetic variation of the low-density lipoprotein receptor-related protein 5 and 6 genes determines fracture risk in elderly white men. J Bone Miner Res 21:141-150
    • (2006) J Bone Miner Res , vol.21 , pp. 141-150
    • Van Meurs, J.B.1    Rivadeneira, F.2    Jhamai, M.3
  • 17
    • 33144477204 scopus 로고    scopus 로고
    • Polymorphisms in the aromatase gene predict areal BMD as a result of affected cortical bone size: The GOOD study
    • Lorentzon M, Swanson C, Eriksson AL et al (2006) Polymorphisms in the aromatase gene predict areal BMD as a result of affected cortical bone size: the GOOD study. J Bone Miner Res 21:332-339
    • (2006) J Bone Miner Res , vol.21 , pp. 332-339
    • Lorentzon, M.1    Swanson, C.2    Eriksson, A.L.3
  • 18
    • 0030869643 scopus 로고    scopus 로고
    • Universal standardization of bone density measurements: A method with optimal properties for calibration among several instruments
    • Hui SL, Gao S, Zhou XH et al (1997) Universal standardization of bone density measurements: a method with optimal properties for calibration among several instruments. J Bone Miner Res 12:1463-1470
    • (1997) J Bone Miner Res , vol.12 , pp. 1463-1470
    • Hui, S.L.1    Gao, S.2    Zhou, X.H.3
  • 19
    • 0034963997 scopus 로고    scopus 로고
    • Standardization of bone mineral density at femoral neck, trochanter and Ward's triangle
    • Lu Y, Fuerst T, Hui S et al (2001) Standardization of bone mineral density at femoral neck, trochanter and Ward's triangle. Osteoporos Int 12:438-444
    • (2001) Osteoporos Int , vol.12 , pp. 438-444
    • Lu, Y.1    Fuerst, T.2    Hui, S.3
  • 20
    • 0029134752 scopus 로고
    • Standardization of spine BMD measurements
    • (1995) Standardization of spine BMD measurements. J Bone Miner Res 10:1602-1603
    • (1995) J Bone Miner Res , vol.10 , pp. 1602-1603
  • 21
    • 0032430986 scopus 로고    scopus 로고
    • Power and sample size calculations for studies involving linear regression
    • Dupont WD, Plummer Jr. WD (1998) Power and sample size calculations for studies involving linear regression. Control Clin Trials 19:589-601
    • (1998) Control Clin Trials , vol.19 , pp. 589-601
    • Dupont, W.D.1    Plummer Jr., W.D.2
  • 22
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J et al (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3
  • 23
    • 14844326069 scopus 로고    scopus 로고
    • Contribution of the LRP5 gene to normal variation in peak BMD in women
    • Koller DL, Ichikawa S, Johnson ML et al (2005) Contribution of the LRP5 gene to normal variation in peak BMD in women. J Bone Miner Res 20:75-80
    • (2005) J Bone Miner Res , vol.20 , pp. 75-80
    • Koller, D.L.1    Ichikawa, S.2    Johnson, M.L.3
  • 24
    • 17544401107 scopus 로고    scopus 로고
    • Seven novel sequence variants in the human low density lipoprotein receptor related protein 5 (LRP5) gene
    • Okubo M, Horinishi A, Kim DH et al (2002) Seven novel sequence variants in the human low density lipoprotein receptor related protein 5 (LRP5) gene. Hum Mutat 19:186
    • (2002) Hum Mutat , vol.19 , pp. 186
    • Okubo, M.1    Horinishi, A.2    Kim, D.H.3
  • 25
    • 33847712958 scopus 로고    scopus 로고
    • The A1330V polymorphism of the low-density lipoprotein receptor-related protein 5 gene (LRP5) associates with low peak bone mass in young healthy men
    • Saarinen A, Valimaki VV, Valimaki MJ et al (2007) The A1330V polymorphism of the low-density lipoprotein receptor-related protein 5 gene (LRP5) associates with low peak bone mass in young healthy men. Bone 40:1006-1012
    • (2007) Bone , vol.40 , pp. 1006-1012
    • Saarinen, A.1    Valimaki, V.V.2    Valimaki, M.J.3
  • 26
    • 33847720301 scopus 로고    scopus 로고
    • Association of a single-nucleotide variation (A1330V) in the low-density lipoprotein receptor-related protein 5 gene (LRP5) with bone mineral density in adult Japanese women
    • Ezura Y, Nakajima T, Urano T et al (2007) Association of a single-nucleotide variation (A1330V) in the low-density lipoprotein receptor-related protein 5 gene (LRP5) with bone mineral density in adult Japanese women. Bone 40:997-1005
    • (2007) Bone , vol.40 , pp. 997-1005
    • Ezura, Y.1    Nakajima, T.2    Urano, T.3
  • 27
    • 34447109293 scopus 로고    scopus 로고
    • The effect of LRP5 polymorphisms on bone mineral density is apparent in childhood
    • Koay MA, Tobias JH, Leary SD et al (2007) The effect of LRP5 polymorphisms on bone mineral density is apparent in childhood. Calcif Tissue Int 81:1-9
    • (2007) Calcif Tissue Int , vol.81 , pp. 1-9
    • Koay, M.A.1    Tobias, J.H.2    Leary, S.D.3
  • 28
    • 33846566222 scopus 로고    scopus 로고
    • Genetic variation at the low-density lipoprotein receptor-related protein 5 (LRP5) locus modulates Wnt signaling and the relationship of physical activity with bone mineral density in men
    • Kiel DP, Ferrari SL, Cupples LA et al (2007) Genetic variation at the low-density lipoprotein receptor-related protein 5 (LRP5) locus modulates Wnt signaling and the relationship of physical activity with bone mineral density in men. Bone 40:587-596
    • (2007) Bone , vol.40 , pp. 587-596
    • Kiel, D.P.1    Ferrari, S.L.2    Cupples, L.A.3
  • 29
    • 34247258995 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein 5 (LRP5) gene polymorphisms are associated with bone mass in both Chinese and whites
    • Xiong DH, Lei SF, Yang F et al (2007) Low-density lipoprotein receptor-related protein 5 (LRP5) gene polymorphisms are associated with bone mass in both Chinese and whites. J Bone Miner Res 22:385-393
    • (2007) J Bone Miner Res , vol.22 , pp. 385-393
    • Xiong, D.H.1    Lei, S.F.2    Yang, F.3


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