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Volumn 10, Issue 5, 2008, Pages 489-500

Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

6 (4 HYDROXYPHENYL) 4 (ALPHA METHYLBENZYLAMINO) 7H PYRROLO[2,3 D]PYRIMIDINE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; IRINOTECAN; LENTIVIRUS VECTOR; PHOSPHOPROTEIN; PROTEIN KINASE B; PROTEIN TYROSINE KINASE INHIBITOR; SHORT HAIRPIN RNA; SODIUM CHLORIDE; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 43249092388     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.08200     Document Type: Article
Times cited : (37)

References (50)
  • 1
    • 0036990103 scopus 로고    scopus 로고
    • The organ microenvironment and cancer metastasis
    • IJ Fidler The organ microenvironment and cancer metastasis Differentiation 70 2002 498 505 (Review).
    • (2002) Differentiation , vol.70 , pp. 498-505
    • Fidler, IJ1
  • 2
    • 0038481970 scopus 로고    scopus 로고
    • The pathogenesis of cancer metastasis: the ‘seed and soil’ hypothesis revisited
    • IJ Fidler The pathogenesis of cancer metastasis: the ‘seed and soil’ hypothesis revisited Nat Rev Cancer 3 2002 453 458 (Timeline).
    • (2002) Nat Rev Cancer , vol.3 , pp. 453-458
    • Fidler, IJ1
  • 3
    • 0036780251 scopus 로고    scopus 로고
    • Clinical translation of angiogenesis inhibitors
    • RS Kerbel J Folkman Clinical translation of angiogenesis inhibitors Nat Rev Cancer 2 2002 727 739
    • (2002) Nat Rev Cancer , vol.2 , pp. 727-739
    • Kerbel, RS1    Folkman, J2
  • 4
    • 0031708626 scopus 로고    scopus 로고
    • Clinical relevance of transforming growth factor alpha, epidermal growth factor receptor, p53, and Ki67 in colorectal liver metastases and corresponding primary tumors
    • KP De Jong R Stelleman A Karrenbeld J Koudstaal AS Gouw WJ Sluiter PM Peters MJ Slooff EG DeVries Clinical relevance of transforming growth factor alpha, epidermal growth factor receptor, p53, and Ki67 in colorectal liver metastases and corresponding primary tumors Hepatology 28 1998 971 979
    • (1998) Hepatology , vol.28 , pp. 971-979
    • De Jong, KP1    Stelleman, R2    Karrenbeld, A3    Koudstaal, J4    Gouw, AS5    Sluiter, WJ6    Peters, PM7    Slooff, MJ8    DeVries, EG9
  • 5
    • 33847068819 scopus 로고    scopus 로고
    • Understanding the new genetics of responsiveness to epidermal growth factor receptor tyrosine kinase inhibitors
    • L Toschi F Cappuzzo Understanding the new genetics of responsiveness to epidermal growth factor receptor tyrosine kinase inhibitors Oncologist 12 2007 211 220
    • (2007) Oncologist , vol.12 , pp. 211-220
    • Toschi, L1    Cappuzzo, F2
  • 6
    • 0027232422 scopus 로고
    • The relationship of quantitative epidermal growth factor receptor expression in non-small cell lung cancer to long-term survival
    • D Veale N Kerr GJ Gibson PJ Kelly AL Harris The relationship of quantitative epidermal growth factor receptor expression in non-small cell lung cancer to long-term survival Br J Cancer 68 1993 162 165
    • (1993) Br J Cancer , vol.68 , pp. 162-165
    • Veale, D1    Kerr, N2    Gibson, GJ3    Kelly, PJ4    Harris, AL5
  • 7
    • 33846696437 scopus 로고    scopus 로고
    • A novel mechanism of resistance to epidermal growth factor receptor antagonism in vivo
    • A Rajput AP Korterba JI Kreisberg JM Foster JK Willson MG Brattain A novel mechanism of resistance to epidermal growth factor receptor antagonism in vivo Cancer Res 67 2007 665 673
    • (2007) Cancer Res , vol.67 , pp. 665-673
    • Rajput, A1    Korterba, AP2    Kreisberg, JI3    Foster, JM4    Willson, JK5    Brattain, MG6
  • 8
    • 0033818695 scopus 로고    scopus 로고
    • Antiangiogenic and antitumor activity of anti-epidermal growth factor receptor C225 monoclonal antibody in combination with vascular endothelial growth factor antisense oligonucleotide in human GEO colon cancer cells
    • F Ciardiello R Bianco V Damiano G Fontanini R Caputo G Romatico S De Placido AR Bianco J Mendelsohn G Tortora Antiangiogenic and antitumor activity of anti-epidermal growth factor receptor C225 monoclonal antibody in combination with vascular endothelial growth factor antisense oligonucleotide in human GEO colon cancer cells Clin Cancer Res 6 2000 3739 3747
    • (2000) Clin Cancer Res , vol.6 , pp. 3739-3747
    • Ciardiello, F1    Bianco, R2    Damiano, V3    Fontanini, G4    Caputo, R5    Romatico, G6    De Placido, S7    Bianco, AR8    Mendelsohn, J9    Tortora, G10
  • 9
    • 1242315584 scopus 로고    scopus 로고
    • Signal transduction and oncogenesis by ErbB/HER receptors
    • MD Marmor KB Skaria Y Yarden Signal transduction and oncogenesis by ErbB/HER receptors Int J Radiat Oncol Biol Phys 58 2004 903 913
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 903-913
    • Marmor, MD1    Skaria, KB2    Yarden, Y3
  • 10
    • 0035045386 scopus 로고    scopus 로고
    • Epidermal growth factor modulates the expression of vascular endothelial growth factor in the human prostate
    • N Ravindranath D Wion P Brachet D Djakiew Epidermal growth factor modulates the expression of vascular endothelial growth factor in the human prostate J Androl 22 2001 432 443
    • (2001) J Androl , vol.22 , pp. 432-443
    • Ravindranath, N1    Wion, D2    Brachet, P3    Djakiew, D4
  • 11
    • 0034212763 scopus 로고    scopus 로고
    • Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma
    • CJ Bruns CC Solorzano MT Harbison S Ozawa R Tsan D Fan J Abbruzzese P Traxler E Buchdunger R Radinsky Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma Cancer Res 60 2000 2926 2935
    • (2000) Cancer Res , vol.60 , pp. 2926-2935
    • Bruns, CJ1    Solorzano, CC2    Harbison, MT3    Ozawa, S4    Tsan, R5    Fan, D6    Abbruzzese, J7    Traxler, P8    Buchdunger, E9    Radinsky, R10
  • 12
    • 0037341379 scopus 로고    scopus 로고
    • Blockade of epidermal growth factor receptor signaling in tumor cells and tumor-associated endothelial cells for therapy of androgen-independent human prostate cancer growing in the bone of nude mice
    • SJ Kim H Uehara T Karashima DL Shepherd JJ Killion IJ Fidler Blockade of epidermal growth factor receptor signaling in tumor cells and tumor-associated endothelial cells for therapy of androgen-independent human prostate cancer growing in the bone of nude mice Clin Cancer Res 9 2003 1200 1210
    • (2003) Clin Cancer Res , vol.9 , pp. 1200-1210
    • Kim, SJ1    Uehara, H2    Karashima, T3    Shepherd, DL4    Killion, JJ5    Fidler, IJ6
  • 14
    • 17844372539 scopus 로고    scopus 로고
    • Critical update and emerging Rtrends in epidermal growth factor receptor targeting in cancer
    • J Baselga CL Arteaga Critical update and emerging Rtrends in epidermal growth factor receptor targeting in cancer J Clin Oncol 23 2005 2445 2459
    • (2005) J Clin Oncol , vol.23 , pp. 2445-2459
    • Baselga, J1    Arteaga, CL2
  • 15
    • 0142055937 scopus 로고    scopus 로고
    • Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial
    • MG Kris RB Natale RS Herbst TJ Lynch Jr D Prager CP Belani JH Schiller K Kelly H Spiridonidis A Sandler Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial JAMA 290 2003 2149 2158
    • (2003) JAMA , vol.290 , pp. 2149-2158
    • Kris, MG1    Natale, RB2    Herbst, RS3    Lynch, TJ4    Prager, D5    Belani, CP6    Schiller, JH7    Kelly, K8    Spiridonidis, H9    Sandler, A10
  • 17
    • 34248186584 scopus 로고    scopus 로고
    • Predicting gefitinib responsiveness in lung cancer by fluorescence in situ hybridization/chromogenic in situ hybridization analysis of EGFR and HER2 in biopsy and cytology specimens
    • L Daniele L Macri M Schena D Dongiovanni L Bonello E Armando L Ciuffreda O Bertetto G Bussolati A Sapino Predicting gefitinib responsiveness in lung cancer by fluorescence in situ hybridization/chromogenic in situ hybridization analysis of EGFR and HER2 in biopsy and cytology specimens Mol Cancer Ther 6 2007 1223 1229
    • (2007) Mol Cancer Ther , vol.6 , pp. 1223-1229
    • Daniele, L1    Macri, L2    Schena, M3    Dongiovanni, D4    Bonello, L5    Armando, E6    Ciuffreda, L7    Bertetto, O8    Bussolati, G9    Sapino, A10
  • 18
    • 20044364933 scopus 로고    scopus 로고
    • EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment
    • A Marchetti C Martella L Felicioni F Barassi S Salvatore A Chella PP Camplese T Iarussi F Mucilli A Mezzetti EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment J Clin Oncol 23 2005 857 865
    • (2005) J Clin Oncol , vol.23 , pp. 857-865
    • Marchetti, A1    Martella, C2    Felicioni, L3    Barassi, F4    Salvatore, S5    Chella, A6    Camplese, PP7    Iarussi, T8    Mucilli, F9    Mezzetti, A10
  • 19
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from ‘never smokers’ and are associated with sensitivity of tumors to gefitinib and erlotinib
    • W Pao V Miller M Zakowski J Doherty K Politi I Sarkaria B Singh R Heelan V Rusch L Fulton EGF receptor gene mutations are common in lung cancers from ‘never smokers’ and are associated with sensitivity of tumors to gefitinib and erlotinib Proc Natl Acad Sci USA 101 2004 13306 13311
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 13306-13311
    • Pao, W1    Miller, V2    Zakowski, M3    Doherty, J4    Politi, K5    Sarkaria, I6    Singh, B7    Heelan, R8    Rusch, V9    Fulton, L10
  • 20
    • 20244389188 scopus 로고    scopus 로고
    • Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with gefitinib
    • SW Han TY Kim PG Hwang S Jeong J Kim IS Choi DY Oh JH Kim DW Kim DH Chung Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with gefitinib J Clin Oncol 23 2005 2493 2501
    • (2005) J Clin Oncol , vol.23 , pp. 2493-2501
    • Han, SW1    Kim, TY2    Hwang, PG3    Jeong, S4    Kim, J5    Choi, IS6    Oh, DY7    Kim, JH8    Kim, DW9    Chung, DH10
  • 24
    • 24644445676 scopus 로고    scopus 로고
    • Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients
    • F Cappuzzo M Varella-Garcia H Shigematsu I Domenichini S Bartolini GL Ceresoli E Rossi V Ludovini V Gregorc L Toschi Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients J Clin Oncol 23 2005 5007 5018
    • (2005) J Clin Oncol , vol.23 , pp. 5007-5018
    • Cappuzzo, F1    Varella-Garcia, M2    Shigematsu, H3    Domenichini, I4    Bartolini, S5    Ceresoli, GL6    Rossi, E7    Ludovini, V8    Gregorc, V9    Toschi, L10
  • 25
    • 0036733591 scopus 로고    scopus 로고
    • Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas
    • CH Baker D Kedar MF McCarty R Tsan KL Weber CD Bucana IJ Fidler Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas Am J Pathol 161 2002 929 938
    • (2002) Am J Pathol , vol.161 , pp. 929-938
    • Baker, CH1    Kedar, D2    McCarty, MF3    Tsan, R4    Weber, KL5    Bucana, CD6    Fidler, IJ7
  • 26
    • 23244462565 scopus 로고    scopus 로고
    • Induction of apoptosis in tumorassociated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice
    • K Yokoi SJ Kim PH Thaker S Yazici DH Nam J He T Sasaki PJ Chiao GM Sclabas JL Abbruzzese Induction of apoptosis in tumorassociated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice Neoplasia 7 2005 696 704
    • (2005) Neoplasia , vol.7 , pp. 696-704
    • Yokoi, K1    Kim, SJ2    Thaker, PH3    Yazici, S4    Nam, DH5    He, J6    Sasaki, T7    Chiao, PJ8    Sclabas, GM9    Abbruzzese, JL10
  • 27
    • 20944433324 scopus 로고    scopus 로고
    • Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model
    • K Yokoi PH Thaker S Yazici RR Rebhun DH Nam J He SJ Kim JL Abbruszzese SR Hamilton IJ Fidler Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model Cancer Res 65 2005 3716 3725
    • (2005) Cancer Res , vol.65 , pp. 3716-3725
    • Yokoi, K1    Thaker, PH2    Yazici, S3    Rebhun, RR4    Nam, DH5    He, J6    Kim, SJ7    Abbruszzese, JL8    Hamilton, SR9    Fidler, IJ10
  • 28
    • 33747880994 scopus 로고    scopus 로고
    • Antivascular therapy of cancer metastasis
    • IJ Fidler Antivascular therapy of cancer metastasis J Surg Oncol 94 2006 178 180 (Editorial Commentary).
    • (2006) J Surg Oncol , vol.94 , pp. 178-180
    • Fidler, IJ1
  • 30
    • 0023917842 scopus 로고
    • In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinoma implanted into nude mice
    • K Morikawa SM Walker JM Jessup IJ Fidler In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinoma implanted into nude mice Cancer Res 48 1988 1943 1948
    • (1988) Cancer Res , vol.48 , pp. 1943-1948
    • Morikawa, K1    Walker, SM2    Jessup, JM3    Fidler, IJ4
  • 31
    • 0043210428 scopus 로고    scopus 로고
    • Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference
    • M Wiznerowicz D Trono Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference J Virol 77 2003 8957 8961
    • (2003) J Virol , vol.77 , pp. 8957-8961
    • Wiznerowicz, M1    Trono, D2
  • 32
    • 3142774878 scopus 로고    scopus 로고
    • AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity
    • P Traxler PR Allegrini R Brandt J Bruegen R Cozens D Fabbro K Grosios HA Lane P McSheehy J Mestan AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity Cancer Res 64 2004 4931 4941
    • (2004) Cancer Res , vol.64 , pp. 4931-4941
    • Traxler, P1    Allegrini, PR2    Brandt, R3    Bruegen, J4    Cozens, R5    Fabbro, D6    Grosios, K7    Lane, HA8    McSheehy, P9    Mestan, J10
  • 33
    • 34547643983 scopus 로고    scopus 로고
    • Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma
    • Y Kitadai T Sasaki T Kuwai T Nakamura CD Bucana IJ Fidler Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma Am J Pathol 169 2006 2054 2065
    • (2006) Am J Pathol , vol.169 , pp. 2054-2065
    • Kitadai, Y1    Sasaki, T2    Kuwai, T3    Nakamura, T4    Bucana, CD5    Fidler, IJ6
  • 34
    • 33644698562 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-negative colorectal cancer: is there truly such an entity?
    • L Saltz Epidermal growth factor receptor-negative colorectal cancer: is there truly such an entity? Clin Colorectal Cancer 5 2005 S98 S100
    • (2005) Clin Colorectal Cancer , vol.5 , pp. S98-S100
    • Saltz, L1
  • 35
    • 33745822760 scopus 로고    scopus 로고
    • Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells in human renal cell carcinoma is a primary target for therapy by tyrosine kinase inhibitors
    • CH Baker MS Pino IJ Fidler Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells in human renal cell carcinoma is a primary target for therapy by tyrosine kinase inhibitors Neoplasia 8 2006 470 476
    • (2006) Neoplasia , vol.8 , pp. 470-476
    • Baker, CH1    Pino, MS2    Fidler, IJ3
  • 36
    • 3042523539 scopus 로고    scopus 로고
    • Simultaneous blockade of platelet-derived growth factor-receptor and epidermal growth factor-receptor signaling and systemic administration of paclitaxel as therapy for human prostate cancer metastasis in bone of nude mice
    • SJ Kim H Uehara S Yazici RR Langley J He R Tsan D Fan JJ Killion IJ Fidler Simultaneous blockade of platelet-derived growth factor-receptor and epidermal growth factor-receptor signaling and systemic administration of paclitaxel as therapy for human prostate cancer metastasis in bone of nude mice Cancer Res 64 2004 4201 4208
    • (2004) Cancer Res , vol.64 , pp. 4201-4208
    • Kim, SJ1    Uehara, H2    Yazici, S3    Langley, RR4    He, J5    Tsan, R6    Fan, D7    Killion, JJ8    Fidler, IJ9
  • 37
    • 36048958903 scopus 로고    scopus 로고
    • Growth factor binding to the pericellular matrix and its importance in tissue engineering
    • L Macri D Silverstein RA Clark Growth factor binding to the pericellular matrix and its importance in tissue engineering Adv Drug Deliv Rev 59 2007 1381
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 1381
    • Macri, L1    Silverstein, D2    Clark, RA3
  • 38
    • 26644472169 scopus 로고    scopus 로고
    • Dual inhibition of the epidermal growth factor and vascular endothelial growth factor phosphorylation for antivascular therapy of human prostate cancer in the prostate of nude mice
    • S Yazici SJ Kim JE Busby J He P Thaker K Yokoi D Fan IJ Fidler Dual inhibition of the epidermal growth factor and vascular endothelial growth factor phosphorylation for antivascular therapy of human prostate cancer in the prostate of nude mice Prostate 65 2005 203 215
    • (2005) Prostate , vol.65 , pp. 203-215
    • Yazici, S1    Kim, SJ2    Busby, JE3    He, J4    Thaker, P5    Yokoi, K6    Fan, D7    Fidler, IJ8
  • 39
    • 27644479545 scopus 로고    scopus 로고
    • Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors
    • PH Thaker S Yazici MB Nilsson K Yokoi RZ Tsan J He SJ Kim IJ Fidler AK Sood Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors Clin Cancer Res 11 2005 4923 4933
    • (2005) Clin Cancer Res , vol.11 , pp. 4923-4933
    • Thaker, PH1    Yazici, S2    Nilsson, MB3    Yokoi, K4    Tsan, RZ5    He, J6    Kim, SJ7    Fidler, IJ8    Sood, AK9
  • 41
    • 20144381957 scopus 로고    scopus 로고
    • Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry
    • KY Chung J Shia NE Kemeny M Shah GK Schwartz A Tse A Hamilton D Pan D Shrag L Schwartz Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry J Clin Oncol 23 2005 1803 1810
    • (2005) J Clin Oncol , vol.23 , pp. 1803-1810
    • Chung, KY1    Shia, J2    Kemeny, NE3    Shah, M4    Schwartz, GK5    Tse, A6    Hamilton, A7    Pan, D8    Shrag, D9    Schwartz, L10
  • 42
    • 33748146468 scopus 로고    scopus 로고
    • Lack of usefulness of epidermal growth factor receptor expression determination for cetuximab therapy in patients with colorectal cancer
    • M Hebbar A Wacrenier C Desauw O Romano S Cattan JP Triboulet FR Pruvot Lack of usefulness of epidermal growth factor receptor expression determination for cetuximab therapy in patients with colorectal cancer Anticancer Drugs 17 2006 855 857
    • (2006) Anticancer Drugs , vol.17 , pp. 855-857
    • Hebbar, M1    Wacrenier, A2    Desauw, C3    Romano, O4    Cattan, S5    Triboulet, JP6    Pruvot, FR7
  • 43
    • 33644849337 scopus 로고    scopus 로고
    • Cetuximab preclinical antitumor activity (monotherapy and combination based) is not predicted by relative total or activated epidermal growth factor receptor tumor expression levels
    • R Wild K Fager C Flefleh D Kan A Camuso K McGlinchey WC Rose Cetuximab preclinical antitumor activity (monotherapy and combination based) is not predicted by relative total or activated epidermal growth factor receptor tumor expression levels Mol Cancer Ther 5 2006 104 113
    • (2006) Mol Cancer Ther , vol.5 , pp. 104-113
    • Wild, R1    Fager, K2    Flefleh, C3    Kan, D4    Camuso, A5    McGlinchey, K6    Rose, WC7
  • 44
    • 0036161382 scopus 로고    scopus 로고
    • The seed and soil hypothesis: vascularization and brain metastases
    • IJ Fidler S Yano RD Zhang T Fujimaki CD Bucana The seed and soil hypothesis: vascularization and brain metastases Lancet Oncol 3 2002 53 57
    • (2002) Lancet Oncol , vol.3 , pp. 53-57
    • Fidler, IJ1    Yano, S2    Zhang, RD3    Fujimaki, T4    Bucana, CD5
  • 45
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis-dependent?
    • J Folkman What is the evidence that tumors are angiogenesis-dependent? J Natl Cancer Inst 82 1990 4 6
    • (1990) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J1
  • 46
    • 0035173755 scopus 로고    scopus 로고
    • Overview of angiogenesis: biologic implications for antiangiogenic therapy
    • LM Ellis W Liu SA Ahmad F Fan YD Jung RM Shaheen N Reinmuth Overview of angiogenesis: biologic implications for antiangiogenic therapy Semin Oncol 28 2001 94 104
    • (2001) Semin Oncol , vol.28 , pp. 94-104
    • Ellis, LM1    Liu, W2    Ahmad, SA3    Fan, F4    Jung, YD5    Shaheen, RM6    Reinmuth, N7
  • 47
    • 34250857019 scopus 로고    scopus 로고
    • Tumor cell-organ microenvironment interactions in the pathogenesis of cancer metastasis
    • RR Langley IJ Fidler Tumor cell-organ microenvironment interactions in the pathogenesis of cancer metastasis Endocr Rev 28 2007 297 321
    • (2007) Endocr Rev , vol.28 , pp. 297-321
    • Langley, RR1    Fidler, IJ2
  • 48
    • 0034161989 scopus 로고    scopus 로고
    • Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies
    • A Eberhard S Kahlert V Goede B Hemmerlein KH Plate GH Augustin Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies Cancer Res 60 2000 1388 1393
    • (2000) Cancer Res , vol.60 , pp. 1388-1393
    • Eberhard, A1    Kahlert, S2    Goede, V3    Hemmerlein, B4    Plate, KH5    Augustin, GH6
  • 49
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couple survival signals to the cell-intrinsic death machinery
    • SR Datta H Dudek X Tao S Masters H Fu Y Gotoh ME Greenberg Akt phosphorylation of BAD couple survival signals to the cell-intrinsic death machinery Cell 91 1997 231 241
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, SR1    Dudek, H2    Tao, X3    Masters, S4    Fu, H5    Gotoh, Y6    Greenberg, ME7
  • 50
    • 2542582262 scopus 로고    scopus 로고
    • Activation of the platelet-derived growth factor receptor enhances survival of murine bone endothelial cells
    • RR Langley D Fan RZ Tsan R Rebhun J He SJ Kim IJ Fidler Activation of the platelet-derived growth factor receptor enhances survival of murine bone endothelial cells Cancer Res 64 2004 3727 3730
    • (2004) Cancer Res , vol.64 , pp. 3727-3730
    • Langley, RR1    Fan, D2    Tsan, RZ3    Rebhun, R4    He, J5    Kim, SJ6    Fidler, IJ7


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