메뉴 건너뛰기




Volumn 100, Issue 5, 2008, Pages 697-700

Pharmacokinetics of intravenous dexmedetomidine in children under 11 yr of age

Author keywords

Children; Pharmacokinetics, dexmedetomidine; Sedation

Indexed keywords

DEXMEDETOMIDINE; MIDAZOLAM; THIOPENTAL; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; HYPNOTIC SEDATIVE AGENT;

EID: 43249090099     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aen070     Document Type: Article
Times cited : (94)

References (20)
  • 1
    • 7244239373 scopus 로고    scopus 로고
    • Dexmedetomidine pharmacodynamics: Part I: crossover comparison of the respiratory effects of dexmedetomidine and remifentanil in healthy volunteers
    • Hsu YW, Cortinez LI, Robertson KM, et al. Dexmedetomidine pharmacodynamics: Part I: crossover comparison of the respiratory effects of dexmedetomidine and remifentanil in healthy volunteers. Anesthesiology 2004; 101: 1066
    • (2004) Anesthesiology , vol.101 , pp. 1066
    • Hsu, Y.W.1    Cortinez, L.I.2    Robertson, K.M.3
  • 2
    • 0037313063 scopus 로고    scopus 로고
    • The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects
    • Nelson LE, Lu J, Guo T, Saper CB, Franks NP, Maze M. The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects. Anesthesiology 2003; 98: 428
    • (2003) Anesthesiology , vol.98 , pp. 428
    • Nelson, L.E.1    Lu, J.2    Guo, T.3    Saper, C.B.4    Franks, N.P.5    Maze, M.6
  • 3
    • 0036166695 scopus 로고    scopus 로고
    • Initial experience with dexmedetomidine in paediatric-aged patients
    • Tobias JD, Berkenbosch JW. Initial experience with dexmedetomidine in paediatric-aged patients. Paediatr Anaesth 2002; 12: 171-5
    • (2002) Paediatr Anaesth , vol.12 , pp. 171-175
    • Tobias, J.D.1    Berkenbosch, J.W.2
  • 4
    • 0642335955 scopus 로고    scopus 로고
    • Additional experience with dexmedetomidine in pediatric patients
    • Tobias JD, Berkenbosch JW, Russo P. Additional experience with dexmedetomidine in pediatric patients. South Med J 2003; 96: 871-5
    • (2003) South Med J , vol.96 , pp. 871-875
    • Tobias, J.D.1    Berkenbosch, J.W.2    Russo, P.3
  • 5
    • 2442584848 scopus 로고    scopus 로고
    • Sedation during mechanical ventilation in infants and children: Dexmedetomidine versus midazolam
    • Tobias JD, Berkenbosch JW. Sedation during mechanical ventilation in infants and children: dexmedetomidine versus midazolam. South Med J 2004; 97: 451-5
    • (2004) South Med J , vol.97 , pp. 451-455
    • Tobias, J.D.1    Berkenbosch, J.W.2
  • 6
    • 14944369631 scopus 로고    scopus 로고
    • Rescue sedation with dexmedetomidine for diagnostic imaging: A preliminary report
    • Nichols DP, Berkenbosch JW, Tobias JD. Rescue sedation with dexmedetomidine for diagnostic imaging: a preliminary report. Paediatr Anaesth 2005; 15: 199-203
    • (2005) Paediatr Anaesth , vol.15 , pp. 199-203
    • Nichols, D.P.1    Berkenbosch, J.W.2    Tobias, J.D.3
  • 7
    • 19944386258 scopus 로고    scopus 로고
    • Sedative, haemodynamic and respiratory effects of dexmedetomidine in children undergoing magnetic resonance imaging examination: Preliminary results
    • Koroglu A, Demirbilek S, Teksan H, Sagir O, But AK, Ersoy MO. Sedative, haemodynamic and respiratory effects of dexmedetomidine in children undergoing magnetic resonance imaging examination: preliminary results. Br J Anaesth 2005; 94: 821-4
    • (2005) Br J Anaesth , vol.94 , pp. 821-824
    • Koroglu, A.1    Demirbilek, S.2    Teksan, H.3    Sagir, O.4    But, A.K.5    Ersoy, M.O.6
  • 10
    • 33645553849 scopus 로고    scopus 로고
    • Use of dexmedetomidine in children after cardiac and thoracic surgery
    • Chrysostomou C, Di Filippo S, Manrique A-M, et al. Use of dexmedetomidine in children after cardiac and thoracic surgery. Pediatr Crit Care Med 2006; 7: 126-87
    • (2006) Pediatr Crit Care Med , vol.7 , pp. 126-187
    • Chrysostomou, C.1    Di Filippo, S.2    Manrique, A.-M.3
  • 11
    • 34547604232 scopus 로고    scopus 로고
    • European Medicines Agency, Note for guidance on clinical investigation of medicinal products in the paediatric population. 2001
    • European Medicines Agency. ICH topic E11, Clinical investigation of medicinal products in the paediatric population. Note for guidance on clinical investigation of medicinal products in the paediatric population. 2001
    • ICH topic E11, Clinical investigation of medicinal products in the paediatric population
  • 12
    • 33750464516 scopus 로고    scopus 로고
    • Effects of low and high plasma concentrations of dexmedetomidine on myocardial perfusion and cardiac function in healthy male subjects
    • Snapir A, Posti J, Kentala E, et al. Effects of low and high plasma concentrations of dexmedetomidine on myocardial perfusion and cardiac function in healthy male subjects. Anesthesiology 2006; 105: 902-10
    • (2006) Anesthesiology , vol.105 , pp. 902-910
    • Snapir, A.1    Posti, J.2    Kentala, E.3
  • 13
    • 0002357422 scopus 로고
    • An information criterion (AIC)
    • Akaike H. An information criterion (AIC). Math Sci 1976; 14: 5-9
    • (1976) Math Sci , vol.14 , pp. 5-9
    • Akaike, H.1
  • 14
    • 0017206538 scopus 로고
    • Linear pharmacokinetic equations allowing direct calculation of many needed pharmacokinetic parameters from the coefficients and exponents of polyexponential equations which have been fitted to the data
    • Wagner JG. Linear pharmacokinetic equations allowing direct calculation of many needed pharmacokinetic parameters from the coefficients and exponents of polyexponential equations which have been fitted to the data. J Pharmacokin Biopharm 1976; 4: 443-67
    • (1976) J Pharmacokin Biopharm , vol.4 , pp. 443-467
    • Wagner, J.G.1
  • 15
    • 0036203258 scopus 로고    scopus 로고
    • Scaling for size: Some implications for paediatric anaesthesia dosing
    • Anderson BJ, Meakin GH. Scaling for size: some implications for paediatric anaesthesia dosing. Paediatr Anaesth 2002; 12: 205
    • (2002) Paediatr Anaesth , vol.12 , pp. 205
    • Anderson, B.J.1    Meakin, G.H.2
  • 16
    • 34548670030 scopus 로고    scopus 로고
    • Pharmacokinetics of dexmedetomidine in postsurgical pediatric intensive care unit patients: Preliminary study
    • Díaz SM, Rodarte A, Foley J, Capparelli EV. Pharmacokinetics of dexmedetomidine in postsurgical pediatric intensive care unit patients: preliminary study. Pediatr Crit Care Med 2007; 8: 419-24
    • (2007) Pediatr Crit Care Med , vol.8 , pp. 419-424
    • Díaz, S.M.1    Rodarte, A.2    Foley, J.3    Capparelli, E.V.4
  • 17
    • 33751312459 scopus 로고    scopus 로고
    • A phase I, two-center study of the pharmacokinetics and pharmacodynamics of dexmedetomidine in children
    • Petroz GC, Sikich N, van Dyk H, Shafer SL, Schily M, Lerman J. A phase I, two-center study of the pharmacokinetics and pharmacodynamics of dexmedetomidine in children. Anesthesiology 2006; 105: 1098-110
    • (2006) Anesthesiology , vol.105 , pp. 1098-1110
    • Petroz, G.C.1    Sikich, N.2    van Dyk, H.3    Shafer, S.L.4    Schily, M.5    Lerman, J.6
  • 18
    • 0027299384 scopus 로고
    • The pharmacokinetics and hemodynamic effects of intravenous and intramuscular dexmedetomidine hydrochloride in adult human volunteers
    • Dyck JB, Maze M, Haack C, Vuorilehto L, Shafer SL. The pharmacokinetics and hemodynamic effects of intravenous and intramuscular dexmedetomidine hydrochloride in adult human volunteers. Anesthesiology 1993; 78: 813-20
    • (1993) Anesthesiology , vol.78 , pp. 813-820
    • Dyck, J.B.1    Maze, M.2    Haack, C.3    Vuorilehto, L.4    Shafer, S.L.5
  • 19
    • 0030862290 scopus 로고    scopus 로고
    • Postoperative pharmacokinetics and sympatholytic effects of dexmedetomidine
    • Talke P, Richardson CA, Scheinin M, Fischer DM. Postoperative pharmacokinetics and sympatholytic effects of dexmedetomidine. Anesth Analg 1997; 85: 1136-42
    • (1997) Anesth Analg , vol.85 , pp. 1136-1142
    • Talke, P.1    Richardson, C.A.2    Scheinin, M.3    Fischer, D.M.4
  • 20
    • 0032855010 scopus 로고    scopus 로고
    • Effects of dexmedetomidine on isoflurane requirements in healthy volunteers. 1: Pharmacodynamic and pharmacokinetic interactions
    • Khan Z, Munday IT, Jones RM, Thornton C, Mant TG, Amin D. Effects of dexmedetomidine on isoflurane requirements in healthy volunteers. 1: Pharmacodynamic and pharmacokinetic interactions. Br J Anaesth 1999; 83: 372-80
    • (1999) Br J Anaesth , vol.83 , pp. 372-380
    • Khan, Z.1    Munday, I.T.2    Jones, R.M.3    Thornton, C.4    Mant, T.G.5    Amin, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.