Human Major Histocompatibility Complex (MHC) class I molecules with disulfide traps secure disease-related antigenic peptides and exclude competitor peptides

Journal of Biological Chemistry

Volumn 283, Issue 12, 2008, Pages 7480-7490

  Truscott, Steven M ^a   Wang, Xiaoli ^a   Lybarger, Lonnie ^c   Biddison, William E ^b   McBerry, Cortez ^d   Martinko, John M ^d   Connolly, Janet M ^a   Linette, Gerald P ^a   Fremont, Daved H ^a   Hansen, Ted H ^a   Carreno, Beatriz M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d SOUTHERN ILLINOIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; COMPETITION; NUCLEIC ACIDS; ORGANIC ACIDS; PEPTIDES; PROTEINS; VACCINES;

ANTIGENIC PEPTIDES; BIOCHEMICAL STABILITIES; CELL SURFACES; CYTOTOXIC T LYMPHOCYTES; DISULFIDE TRAPS; DNA VACCINATIONS; EXOGENOUS PEPTIDES; HEAVY CHAINS; HUMAN DISEASES; IN CELLS; MAJOR HISTOCOMPATIBILITY COMPLEX CLASSES; MHC CLASSES; MOUSE MODELS; MULTIMERIC; POLYPEPTIDE CHAINS; RECOMBINANT PROTEINS; SINGLE CHAINS; T CELLS; TETRAMERS; VACCINE DEVELOPMENTS;

AMINES;

DISULFIDE; DNA VACCINE; HLA ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE; EPITOPE; HLA A ANTIGEN; HLA A0201 ANTIGEN; HLA-A0201 ANTIGEN;

ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CELL SURFACE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DRUG DESIGN; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; ANIMAL; CYTOLOGY; GENETICS; HELA CELL; IMMUNOLOGY; MOUSE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; VACCINATION;

ANIMALS; DISULFIDES; EPITOPES, T-LYMPHOCYTE; HELA CELLS; HLA-A ANTIGENS; HUMANS; MICE; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; T-LYMPHOCYTES, CYTOTOXIC; VACCINATION; VACCINES, DNA;

EID: 43149103191     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M709935200     Document Type: Article

References (56)

1. Lurquin, C., Van Pel, A., Mariame, B., De Plaen, E., Szikora, J. P., Janssens, C., Reddehase, M. J., Lejeune, J., and Boon, T. (1989) Cell 58, 293-303
2. Peters, B., Sidney, J., Bourne, P., Bui, H. H., Buus, S., Doh, G., Fleri, W., Kronenberg, M., Kubo, R., Lund, O., Nemazee, D., Ponomarenko, J. V., Sathiamurthy, M., Schoenberger, S., Stewart, S., Surko, P., Way, S., Wilson, S., and Sette, A. (2005) PLoS. Biol. 3, e91
3. Kannagi, M., Shida, H., Igarashi, H., Kuruma, K., Murai, H., Aono, Y., Maruyama, I., Osame, M., Hattori, T., Inoko, H., and Harada, S. (1992) J. Virol. 66, 2928-2933
4. Morrison, J., Elvin, J., Latron, F., Gotch, F., Moots, R., Strominger, J. L., and McMichael, A. (1992) Eur. J. Immunol. 22, 903-907
5. Kawakami, Y., Eliyahu, S., Jennings, C., Sakaguchi, K., Kang, X., Southwood, S., Robbins, P. F., Sette, A., Appella, E., and Rosenberg, S. A. (1995) J. Immunol. 154, 3961-3968
6. Huet, S., Nixon, D. F., Rothbard, J. B., Townsend, A., Ellis, S. A., and McMichael, A. J. (1990) Int. Immunol. 2, 311-316
7. Purcell, A. W., McCluskey, J., and Rossjohn, J. (2007) Nat. Rev. Drug Discov. 6, 404-414
8. Altman, J. D., Moss, P. A. H., Goulder, P. J. R., Barouch, D. H., McHeyzer-Williams, M. G., Bell, J. I., McMichael, A. J., and Davis, M. M. (1996) Science 274, 94-96
9. Altman, J. D. (2004) Methods Cell Biol. 75, 433-452
10. Yu, Y. Y., Netuschil, N., Lybarger, L., Connolly, J. M., and Hansen, T. H. (2002) J. Immunol. 168, 3145-3149
11. Primeau, T., Myers, N. B., Yu, Y. Y., Lybarger, L., Wang, X., Truscott, S. M., Hansen, T. H., and Connolly, J. M. (2005) Immunol. Res. 32, 109-122
12. Hansen, T. H., and Lybarger, L. (2006) Cancer Immunol. Immunother. 55, 235-236
13. Jaramillo, A., Narayanan, K., Campbell, L. G., Benshoff, N. D., Lybarger, L., Hansen, T. H., Fleming, T. P., Dietz, J. R., and Mohanakumar, T. (2004) Breast Cancer Res. Treat. 88, 29-41
14. Huang, C. H., Peng, S., He, L., Tsai, Y. C., Boyd, D. A., Hansen, T. H., Wu, T. C., and Hung, C. F. (2005) Gene Ther. 12, 1180-1186
15. Hung, C. F., Calizo, R., Tsai, Y. C., He, L., and Wu, T. C. (2007) Vaccine 25, 127-135
16. Zhang, Y., Li, S., Shan, M., Pan, X., Zhuang, K., He, L., Gould, K., and Tien, P. (2007) Immunology 121, 105-112
17. Greten, T. F., Korangy, F., Neumann, G., Wedemeyer, H., Schlote, K., Heller, A., Scheffer, S., Pardoll, D. M., Garbe, A. I., Schneck, J. P., and Manns, M. P. (2002) J. Immunol. Methods 271, 125-135
18. Lybarger, L., Yu, Y. Y., Miley, M. J., Fremont, D. H., Myers, N., Primeau, T., Truscott, S. M., Connolly, J. M., and Hansen, T. H. (2003) J. Biol. Chem. 278, 27105-27111
19. Oved, K., Lev, A., Noy, R., Segal, D., and Reiter, Y. (2005) Cancer Immunol. Immunother. 54, 867-879
20. Princiotta, M. F., Finzi, D., Qian, S. B., Gibbs, J., Schuchmann, S., Buttgereit, F., Bennink, J. R., and Yewdell, J. W. (2003) Immunity 18, 343-354
21. Yewdell, J. W., Reits, E., and Neefjes, J. (2003) Nat. Rev. Immunol. 3, 952-961
22. Ge, Q., Stone, J. D., Thompson, M. T., Cochran, J. R., Rushe, M., Eisen, H. N., Chen, J., and Stern, L. J. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 13729-13734
23. Schott, E., Bertho, N., Ge, Q., Maurice, M. M., and Ploegh, H. L. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 13735-13740
24. Mitaksov, V., Truscott, S. M., Lybarger, L., Connolly, J. M., Hansen, T. H., and Fremont, D. H. (2007) Chem. Biol. 14, 909-922
25. Truscott, S. M., Lybarger, L., Martinko, J. M., Mitaksov, V. E., Kranz, D. M., Connolly, J. M., Fremont, D. H., and Hansen, T. H. (2007) J. Immunol. 178, 6280-6289
26. Yewdell, J. W., and Bennink, J. R. (1999) Annu. Rev. Immunol. 17, 51-88
27. Parkhurst, M. R., Salgaller, M. L., Southwood, S., Robbins, P. F., Sette, A., Rosenberg, S. A., and Kawakami, Y. (1996) J. Immunol. 157, 2539-2548
28. Lie, W. R., Myers, N. B., Connolly, J. M., Gorka, J., Lee, D. R., and Hansen, T. H. (1991) J. Exp. Med. 173, 449-459
29. Smith, J. D., Myers, N. B., Gorka, J., and Hansen, T. H. (1993) J. Exp. Med. 178, 2035-2046
30. Yu, Y. Y., Myers, N. B., Hilbert, C. M., Harris, M. R., Balendiran, G. K., and Hansen, T. H. (1999) Int. Immunol. 11, 1897-1906
31. Myers, N. B., Harris, M. R., Connolly, J. M., Lybarger, L., Yu, Y. Y., and Hansen, T. H. (2000) J. Immunol. 165, 5656-5663
32. Harris, M. R., Lybarger, L., Myers, N. B., Hilbert, C., Solheim, J. C., Hansen, T. H., and Yu, Y. Y. (2001) Int. Immunol. 13, 1275-1282
33. Brodsky, F. M., Parham, P., Barnstable, C. J., Crumpton, M. J., and Bodmer, W. F. (1979) Immunol. Rev. 47, 3-61
34. Ellis, S. A., Taylor, C., and McMichael, A. (1982) Hum. Immunol. 5, 49-59
35. Stam, N. J., Vroom, T. M., Peters, P. J., Pastoors, E. B., and Ploegh, H. L. (1990) Int. Immunol. 2, 113-125
36. Reddehase, M. J., Rothbard, J. B., and Koszinowski, U. H. (1989) Nature 337, 651-653
37. Carreno, B. M., Anderson, R. W., Coligan, J. E., and Biddison, W. E. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 3420-3424
38. Utz, U., Banks, D., Jacobson, S., and Biddison, W. E. (1996) J. Virol. 70, 843-851
39. Biddison, W. E., Turner, R. V., Gagnon, S. J., Lev, A., Cohen, C. J., and Reiter, Y. (2003) J. Immunol. 171, 3064-3074
40. Wang, Z., Turner, R., Baker, B. M., and Biddison, W. E. (2002) J. Immunol. 169, 3146-3154
41. Carreno, B. M., Turner, R. V., Biddison, W. E., and Coligan, J. E. (1992) J. Immunol. 148, 894-899
42. Linette, G. P., Zhang, D., Hodi, F. S., Jonasch, E. P., Longerich, S., Stowell, C. P., Webb, I. J., Daley, H., Soiffer, R. J., Cheung, A. M., Eapen, S. G., Fee, S. V., Rubin, K. M., Sober, A. J., and Haluska, F. G. (2005) Clin. Cancer Res. 11, 7692-7699
43. Kawakami, Y., Eliyahu, S., Delgado, C. H., Robbins, P. F., Sakaguchi, K., Appella, E., Yannelli, J. R., Adema, G. J., Miki, T., and Rosenberg, S. A. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 6458-6462
44. Poiesz, B. J., Ruscetti, F. W., Gazdar, A. F., Bunn, P. A., Minna, J. D., and Gallo, R. C. (1980) Proc. Natl. Acad. Sci. U. S. A. 77, 7415-7419
45. Granfors, K., Marker-Hermann, E., de Keyser, F., Khan, M. A., Veys, E. M., and Yu, D. T. (2002) Arthritis Rheum. 46, 606-613
46. Stevenson, F. K., Ottensmeier, C. H., Johnson, P., Zhu, D., Buchan, S. L., McCann, K. J., Roddick, J. S., King, A. T., McNicholl, F., Savelyeva, N., and Rice, J. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 14646-14652
47. Donnelly, J. J., Wahren, B., and Liu, M. A. (2005) J. Immunol. 175, 633-639
48. Truscott, S. M. (2007) Engineering and Applications of Single Chain Trimers of Major Histocompatibility Complex Class I Molecules, PhD Thesis, Washington University, St. Louis, MO
49. Kim, S., Poursine-Laurent, J., Truscott, S. M., Lybarger, L., Song, Y. J., Yang, L., French, A. R., Sunwoo, J. B., Lemieux, S., Hansen, T. H., and Yokoyama, W. M. (2005) Nature 436, 709-713
50. Parker, K. C., Bednarek, M. A., and Coligan, J. E. (1994) J. Immunol. 152, 163-175
51. Lazarski, C. A., Chaves, F. A., Jenks, S. A., Wu, S., Richards, K. A., Weaver, J. M., and Sant, A. J. (2005) Immunity 23, 29-40
52. Lauterbach, H., Gruber, A., Ried, C., Cheminay, C., and Brocker, T. (2006) J. Immunol. 176, 4600-4607
53. Crew, M. D., Cannon, M. J., Phanavanh, B., and Garcia-Borges, C. N. (2005) Mol. Immunol. 42, 1205-1214
54. Choudhuri, K., Wiseman, D., Brown, M. H., Gould, K., and van der Merwe, P. A. (2005) Nature 436, 578-582
55. Yachi, P. P., Ampudia, J., Gascoigne, N. R., and Zal, T. (2005) Nat. Immunol. 6, 785-792
56. Garboczi, D. N., Ghosh, P., Utz, U., Fan, Q. R., Biddison, W. E., and Wiley, D. C. (2006) Nature 384, 134-141