Preparation and evaluation of procaine gels for the enhanced local anesthetic action

Archives of Pharmacal Research

Volumn 31, Issue 2, 2008, Pages 235-241

  Jin, Woo Gwan ^a   Shin, Sang Chul ^a  

^a Chonnam National University   (South Korea)

Author keywords

Bioadhesive forces; Enhancer; Hydroxypropyl methylcellulose; Local anesthetics; Procaine; Tail flick analgesic test

Indexed keywords

ADHESIVE AGENT; CELLULOSE; DRUG DERIVATIVE; EXCIPIENT; HYDROXYPROPYLMETHYLCELLULOSE; LOCAL ANESTHETIC AGENT; METHYLCELLULOSE; PROCAINE;

ANIMAL; ARTICLE; ARTIFICIAL MEMBRANE; CHEMISTRY; DRUG EFFECT; GEL; IN VITRO STUDY; MALE; PAIN ASSESSMENT; RAT; REACTION TIME; SKIN ABSORPTION; SPRAGUE DAWLEY RAT; VISCOSITY;

ADHESIVES; ANESTHETICS, LOCAL; ANIMALS; CELLULOSE; EXCIPIENTS; GELS; MALE; MEMBRANES, ARTIFICIAL; METHYLCELLULOSE; PAIN MEASUREMENT; PROCAINE; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; SKIN ABSORPTION; VISCOSITY;

EID: 42949144548     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-001-1147-9     Document Type: Article

References (33)

1. Advokat, C., Evidence for conditioned tolerance of the tail flick reflex. Behav. Neur. Biol., 29, 385-389 (1980).
2. Angust, B. J. and Rogers, N. Y., Comparison of the effects of various transmucosal absorption promoters on buccal insulin delivery. Int. J. Pharm., 53, 227-235 (1989).
3. Ben-David, B., DeMeo, P. J., Lucyk, C., and Solosko, D. A., Comparison of minidose lidocaine-fentanyl spinal anesthesia and local anesthesia/protocol infusion for outpatient knee arthroscopy. Anesth. Analg., 93, 319-325 (2001).
4. Blanco-Fuente, H., Anguiano, S., Otero-Espinar, F. J., and Blanco-Mendez, J., In-vitro bioadhesion of carbopol hydrogels. Int. J. Pharm., 142, 169-174 (1996).
5. Blank, I. H., Scheulpein, R. J., and McFarlane, D. J., Mechaism of percutaneous absorption. 3. The effect of temperature on the transport of non-electrolytes across the skin. J. Invest. Dermatol., 49, 582 (1967).
6. Cho, C. W., Shin, S. C., and Oh, I. J., Thermorheological properties of aqueous solutions and gels of poloxamer 407. Drug Dev. Ind. Pharm., 23, 1227-1232 (1997).
7. Elfbaum, S. and Laden, K., The effect of dimethyl sulphoxide percutaneous absorption. J. Soc. Cosmet. Chem., 19, 119-127 (1968).
8. Evrard, D., Touitou, E., Kolusheva, S., Fishov, Y., and Jelinek, R., A new colorimetric assay for studying and rapid screening of membrane penetration enhancers. Pharm. Res., 18, 943-949 (2001).
9. Grant, G. J., Zakowski, M. I., Vermeulen, K., Langerman, L., Mamanathan, S., and Turndorf, H., Assessing local anesthetic effect using the mouse tail flick test. J. Pharmacol. Toxicol. Meth., 29, 223-226 (1993).
10. Hadgraft, J., Penetration enhancers in percutaneous absorption. Pharm. Int. 5, 252-254 (1984).
11. Haigh, J. M. and Smith, E. W., The selection and use of natural and synthetic membranes for in vitro diffusion experiments. Eur. J. Pharm. Sci., 2, 311-330 (1994).
12. Hernandez-Delgadillo, G. P. and Cruz, S. L., Endogenenous opioids are involved in morphine and dipyrone analgesic potentiation in the tail flick test in rats. Eur. J. Pharmacol., 546, 54-59 (2006).
13. Hou, S. M. and Yu, H. Y., Comparison of absorption of aqueous lidocaine and liposome lidocaine following topical application on rabbit vessels. J. Orthopedic Res., 12, 294-298 (1994).
14. Hou, S. M. and Yu, H. Y., Comparison of systemic absorption of aqueous lidocaine and liposome lidocaine following intra-articular injection in rabbits. J. Forms. Med. Assoc., 96, 141-143 (1997).
15. Ishida, M., Machida, Y., Nambu, N., and Nagai, T., New mucosal dosage form of insulin. Chem. Pharm. Bull., 209, 810-816 (1981).
16. Kenji, K. and Funakoshi, M., A quantitative study on the tail flick test in the rat. Physiol. & Behav. 39, 235-240 (1987).
17. Luo, Y., McNamara, B., Fennell, M. A., Teleis, D. C., May, L., Rudy, J., Watson, A. O., Uboh, C. E., and Soma, L. R., Quantification of penicillin-G and procaine in equine urine and plasma using high-performance liquid chromatography. J. Chromato. B: Biomed. Sci. Applicat., 714, 269-276 (1998).
18. Magnusson, B. M. and Runn, P., Effect of penetration enhancers on the permeation of the thyrotropin releasing hormone analogue pGlu-3-methyl-His-Pro amide through human epidermis. Int. J. Pharm., 178, 149-159 (1999).
19. Miyazaki, S., Ishii, K., and Takada, M., Controlled release of anticancer agents through ethylene-vinyl acetate copolymer membranes. Yakuzaigaku, 42, 259 (1983).
20. Moncada, A., Cendan, C. M. Baeyens, J. M., and Pozo, E. D., Inhibitors of serine/threonine protein phosphatases antagonize the antinoception induced by agonists of alpha two adrenoceptors and GABAB but not k-opoid receptors in the tail flick test in mice. Pain, 114, 212-220 (2005).
21. Morganti, P., Ruocco, E., Wolf, R., and Ruocco, V., Percutaneous absorption and delivery systems (3). Clin. Dermatol., 19, 489-501 (2001).
22. Park, K., A new approach to study mucoadhesion colloidal gold staining. Int. J. Pharm., 53, 209-217 (1989).
23. Prasad, K. N., Luong, T. T., Florence, A. T., Paris, J., Vaution, C., Seiller, M., and Puissieux, F., Surface activity and association of ABA polyoxyethylene-polyoxypropylene block copolymers in aqueous solution. J. Colloid Interface Sci., 69, 225-231(1979).
24. Shin, S. C., Cho, C. W., and Choi, H. K., Permeation of piroxicam from the poloxamer gels. Drug Dev. Ind. Pharm., 25, 1273-1278 (1999).
25. Shin, S. C. and Kim, J. Y., Enhanced permeation of triamcinolone acetonide through the buccal mucosa. Eur. J. Pharm. Biopharm. 50, 217-220 (2000).
26. Shin, S. C., Kim, J. Y., and Oh, I. J., Mucoadhesive and physicochemical characterization of carbopol-poloxamer gels containing triamcinolone acetonide. Drug Dev. Ind. Pharm., 26, 307-312 (2000).
27. Shokri, J., Nokhodchi, A., Dashbolaghi, A., Hassan-Zadeh, D., Ghafourian, T., and Barzegar, J. M., The effect of surfactants on the skin penetration of diazepam. Int. J. Pharm., 228, 99-107 (2001).
28. Storms, M. L. and Stewart, J. T., Stability-indicating HPLC assays for the determination of prilocaine and procaine drug combinations. J. Pharm. Biomed. Analysis, 30, 49-58 (2002).
29. Strichartz, G. R. and Richie, J. M., The action of local anesthetics on I: ion channels of excitable tissues. In Strichartz, G.R. (Eds). Local Anesthetics Handbook of Experimental Pharmacology, vol. 81, Springer Verlag, Berlin, 1987, pp. 21-53.
30. Tur, K. M. and Ch'ng, H. S., Evaluation of possible mechanisms of bioadhesion. Int. J. Pharm., 160, 61-74 (1998).
31. Williams, A. C. and Bary, B. W., Skin absorption enhancers, Crit. Rev. Ther. Drug, 9, 305-353 (1992).
32. Wu, P. C., Huang, Y. B., Fang, J. Y., and Tsai, Y. H., In vitro percutaneous absorption of captopril. Int. J. Pharm., 148, 41-46 (1997).
33. Yuk, S. H., Lee, S. J., Okano, T., Berner, B., and Kim, S. W., One-way membrane for transdermal drug delivery systems. I. membrane preparation and characterization. Int. J. Pharm., 77, 221-229 (1991).