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Volumn 4, Issue 2, 2008, Pages 190-193

Anti-tubercular and anti-inflammatory activities of azetidin-2-one derivatives and their effects on the activity of phospholipase A2

Author keywords

); Anti inflammatory; Antitubercular; Azetidin 2 one derivatives; Mycobacterium tuberculosis (Mtb); Phospholipase A2 (PLA2

Indexed keywords

2 AZETIDINONE DERIVATIVE; ISONIAZID; PHOSPHOLIPASE A2; ANTIINFLAMMATORY AGENT; AZETIDINE DERIVATIVE; TUBERCULOSTATIC AGENT;

EID: 42949122991     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340608783789149     Document Type: Article
Times cited : (6)

References (25)
  • 1
    • 0030614354 scopus 로고    scopus 로고
    • Dennis, D. A. Trends Biochem. Sci., 1997, 22, 1.
    • Dennis, D. A. Trends Biochem. Sci., 1997, 22, 1.
  • 22
    • 42949096899 scopus 로고    scopus 로고
    • Yamakawa, M.; Nozaki, M.; Hokoma, Z. In Animal, Plant and Microbial Toxins; Ohsaka, A., Ed.; Plenum New York, 1976; 1, pp 97-118.
    • Yamakawa, M.; Nozaki, M.; Hokoma, Z. In Animal, Plant and Microbial Toxins; Ohsaka, A., Ed.; Plenum New York, 1976; Vol. 1, pp 97-118.
  • 24
    • 42949140318 scopus 로고    scopus 로고
    • 4a: mp 63-05 °C; IR (KBr, 1609 cm-1 (aromatic C=C, 1667 (C=O, 1059, N-C=O, 3299, COOH) cm-1; 1H NMR (DMSOd6, δ 6.8- 7.6 (m, 12H, Ar-H, 2.9 (d, Ha, CH, 2.5 (d, Hb, CH, 12.2 (s, COOH, 2.0 (a, CH2) Anal. Calcd for C23H17O4NFCl (426, C, 68.48; H, 4.07; N, 3.80. Found: C, 68.38; H, 4.02; N, 3.75. 4b: mp 85-87 °C; IR (KBr, 1620 cm-1 (aromatic C=C, 1681 (C=O, 1059, N-C=O, 3344, COOH) cm-1; 1H NMR (DMSO-d6, δ 6.4- 7.7 (m, 12H Ar-H, 2.8 (d, Ha CH, 3.5 (d, Hb, CH, 12.1 (s, COOH, 2.2 (s, CH2).Anal. Calcd for C23H17O5NFCl (442, C, 65.79; H, 3.91; N, 3.65. Found: C, 65.59; H, 3.86. N, 3.62. 4c: mp 71-73 °C; IR (KBr);1637 cm-1 (aromatic C=C, 1651 (C=O, 1031, N-C=O, 3234, COOH)'cm-1; 1H NMR
    • 2FCl (486): C, 58.74; H, 3.26, N, 6.53. Found: C, 58.32; H, 3.11; N, 6.32.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.