Sugar-substitutes 2-azetidinone cholesterol absorption inhibitors: Enhanced potency by modification of the sugar

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 3, 1998, Pages 313-318

  Vaccaro, Wayne D ^a   Davis Jr , Harry R ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZETIDINONE DERIVATIVE; CHOLESTEROL; EZETIMIBE; UNCLASSIFIED DRUG; 2 AZETIDINONE; 2-AZETIDINONE; AZETIDINE DERIVATIVE; CARBOHYDRATE; HYPOCHOLESTEROLEMIC AGENT;

ARTICLE; CHEMICAL MODIFICATION; DRUG SYNTHESIS; GLYCOSYLATION; HAMSTER; LIPID ABSORPTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; ANIMAL; BLOOD; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER; MASS SPECTROMETRY; METABOLISM;

CRICETINAE;

ANIMALS; ANTICHOLESTEREMIC AGENTS; AZETIDINES; CARBOHYDRATES; CHOLESTEROL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032477602     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00008-0     Document Type: Article

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