Buthionine sulfoximine has anti-Trypanosoma cruzi activity in a murine model of acute Chagas' disease and enhances the efficacy of nifurtimox

Antimicrobial Agents and Chemotherapy

Volumn 52, Issue 5, 2008, Pages 1837-1839

  Faúndez, Mario ^a,b   López Muñoz, Rodrigo ^a   Torres, Gloria ^a   Morello, Antonio ^a   Ferreira, Jorge ^a   Kemmerling, Ulrike ^a   Orellana, Myriam ^a   Maya, Juan D ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSIDAD DE VALPARAÍSO   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

BUTHIONINE SULFOXIMINE; NIFURTIMOX;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROTOZOAL ACTIVITY; ARTICLE; CHAGAS DISEASE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG POTENTIATION; EXPERIMENTAL INFECTION; HEART; MONOTHERAPY; MOUSE; NONHUMAN; PARASITEMIA; PRIORITY JOURNAL; SURVIVAL RATE; TRYPANOSOMA CRUZI;

ACUTE DISEASE; ANIMALS; BUTHIONINE SULFOXIMINE; CHAGAS DISEASE; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; MICE; MICE, INBRED BALB C; NIFURTIMOX; SURVIVAL RATE; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

EID: 42949119652     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.01454-07     Document Type: Article

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