Time-dependent effects of ATP and its degradation products on inflammatory markers in human blood ex vivo

Immunobiology

Volumn 213, Issue 5, 2008, Pages 389-397

  Swennen, Els L R ^a   Coolen, Erik J C M ^a   Arts, Ilja C W ^a   Bast, Aalt ^a   Dagnelie, Pieter C ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

ATP; Cytokines; Human blood; Inflammation

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; GAMMA INTERFERON; HYPOXANTHINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; PHYTOHEMAGGLUTININ; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BLOOD; CONTROLLED STUDY; CYTOKINE RELEASE; EX VIVO STUDY; FEMALE; HUMAN; IMMUNOMODULATION; INFLAMMATION; MALE; PRIORITY JOURNAL;

EID: 42949103473     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2007.10.007     Document Type: Article

References (37)

1. M.P. Abbracchio G. Burnstock Purinoceptors: are there families of P2X and P2Y purinoceptors? Pharmacol. Ther. 64 1994 445 475
2. P.J. Barnes M. Karin Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases N. Engl. J. Med. 336 1997 1066 1071
3. G. Bonizzi M. Karin The two NF-kappaB activation pathways and their role in innate and adaptive immunity Trends Immunol. 25 2004 280 288
4. M.G. Bouma R.K. Stad F.A. van den Wildenberg W.A. Buurman Differential regulatory effects of adenosine on cytokine release by activated human monocytes J. Immunol. 153 1994 4159 4168
5. M.J. Bours E.L. Swennen F. Di Virgilio B.N. Cronstein P.C. Dagnelie Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation Pharmacol. Ther. 112 2006 358 404
6. G. Burnstock G.E. Knight Cellular distribution and functions of P2 receptor subtypes in different systems Int. Rev. Cytol. 240 2004 31 304
7. S. Cadenas A.M. Cadenas Fighting the stranger-antioxidant protection against endotoxin toxicity Toxicology 180 2002 45 63
8. S.B. Coade J.D. Pearson Metabolism of adenine nucleotides in human blood Circ. Res. 65 1989 531 537
9. D. Communi C. Govaerts M. Parmentier J.M. Boeynaems Cloning of a human purinergic P2Y receptor coupled to phospholipase C and adenylyl cyclase J. Biol. Chem. 272 1997 31969 31973
10. D. Communi B. Robaye J.M. Boeynaems Pharmacological characterization of the human P2Y11 receptor Br. J. Pharmacol. 128 1999 1199 1206
11. D. Communi N.S. Gonzalez M. Detheux S. Brezillon V. Lannoy M. Parmentier J.M. Boeynaems Identification of a novel human ADP receptor coupled to G(i) J. Biol. Chem. 276 2001 41479 41485
12. J.H. Curfs J.F. Meis J.A. Hoogkamp-Korstanje A primer on cytokines: sources, receptors, effects, and inducers Clin. Microbiol. Rev. 10 1997 742 780
13. A.A. Erdmann Z.G. Gao U. Jung J. Foley T. Borenstein K.A. Jacobson D.H. Fowler Activation of Th1 and Tc1 cell adenosine A2A receptors directly inhibits IL-2 secretion in vitro and IL-2-driven expansion in vivo Blood 105 2005 4707 4714
14. D. Ferrari P. Chiozzi S. Falzoni S. Hanau F. Di Virgilio Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin J. Exp. Med. 185 1997 579 582
15. D. Ferrari A. La Sala P. Chiozzi A. Morelli S. Falzoni G. Girolomoni M. Idzko S. Dichmann J. Norgauer F. Di Virgilio The P2 purinergic receptors of human dendritic cells: identification and coupling to cytokine release FASEB J. 14 2000 2466 2476
16. C.B. Grahames A.D. Michel I.P. Chessell P.P. Humphrey Pharmacological characterization of ATP- and LPS-induced IL-1beta release in human monocytes Br. J. Pharmacol. 127 1999 1915 1921
17. G. Hasko B.N. Cronstein Adenosine: an endogenous regulator of innate immunity Trends Immunol. 25 2004 33 39
18. G. Hasko D.G. Kuhel Z.H. Nemeth J.G. Mabley R.F. Stachlewitz L. Virag Z. Lohinai G.J. Southan A.L. Salzman C. Szabo Inosine inhibits inflammatory cytokine production by a posttranscriptional mechanism and protects against endotoxin-induced shock J. Immunol. 164 2000 1013 1019
19. S. Heptinstall A. Johnson J.R. Glenn A.E. White Adenine nucleotide metabolism in human blood – important roles for leukocytes and erythrocytes J. Thromb. Haemost. 3 2005 2331 2339
20. M.A. Hofmann S. Schiekofer B. Isermann M. Kanitz M. Henkels M. Joswig A. Treusch M. Morcos T. Weiss V. Borcea A.K. Abdel Khalek J. Amiral H. Tritschler E. Ritz P. Wahl R. Ziegler A. Bierhaus P.P. Nawroth Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-kappaB Diabetologia 42 1999 222 232
21. M. Karin Y. Ben Neriah Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity Annu. Rev. Immunol. 18 2000 621 663
22. V. Lazaron D.L. Dunn Molecular biology of endotoxin antagonism World J. Surg. 26 2002 790 798
23. J.G. Mabley P. Pacher L. Liaudet F.G. Soriano G. Hasko A. Marton C. Szabo A.L. Salzman Inosine reduces inflammation and improves survival in a murine model of colitis Am. J. Physiol. Gastrointest. Liver Physiol. 284 2003 G138 G144
24. A. Marton P. Pacher K.G. Murthy Z.H. Nemeth G. Hasko C. Szabo Anti-inflammatory effects of inosine in human monocytes, neutrophils and epithelial cells in vitro Int. J. Mol. Med. 8 2001 617 621
25. P.N. Moynagh The NF-kappaB pathway J. Cell Sci. 118 2005 4589 4592
26. V. Ralevic G. Burnstock Receptors for purines and pyrimidines Pharmacol. Rev. 50 1998 413 492
27. D.G. Remick Interleukin-8 Crit. Care Med. 33 2005 S466 S467
28. J.M. Sanz F. Di Virgilio Kinetics and mechanism of ATP-dependent IL-1 beta release from microglial cells J. Immunol. 164 2000 4893 4898
29. M. Schnurr T. Toy A. Shin G. Hartmann S. Rothenfusser J. Soellner I.D. Davis J. Cebon E. Maraskovsky Role of adenosine receptors in regulating chemotaxis and cytokine production of plasmacytoid dendritic cells Blood 103 2004 1391 1397
30. P.D. Schweinsberg T.L. Loo Simultaneous analysis of ATP, ADP, AMP, and other purines in human erythrocytes by high-performance liquid chromatography J. Chromatogr. 181 1980 103 107
31. M.V. Sitkovsky Use of the A(2A) adenosine receptor as a physiological immunosuppressor and to engineer inflammation in vivo Biochem. Pharmacol. 65 2003 493 501
32. E.L. Swennen A. Bast P.C. Dagnelie Immunoregulatory effects of adenosine 5′-triphosphate on cytokine release from stimulated whole blood Eur. J. Immunol. 35 2005 852 858
33. E.L. Swennen A. Bast P.C. Dagnelie Purinergic receptors involved in the immunomodulatory effects of ATP in human blood Biochem. Biophys. Res. Commun. 348 2006 1194 1199
34. I. Von Kugelgen Pharmacological profiles of cloned mammalian P2Y-receptor subtypes Pharmacol. Ther. 110 2005 415 432
35. I. von Kugelgen A. Wetter Molecular pharmacology of P2Y-receptors Naunyn Schmiedebergs Arch. Pharmacol. 362 2000 310 323
36. J.G. Zhang L. Hepburn G. Cruz R.A. Borman K.L. Clark The role of adenosine A2A and A2B receptors in the regulation of TNF-alpha production by human monocytes Biochem. Pharmacol. 69 2005 883 889
37. H. Zimmermann Extracellular metabolism of ATP and other nucleotides Naunyn Schmiedebergs Arch. Pharmacol. 362 2000 299 309