Tumor necrosis factor-α levels decrease with anticytokine therapy in patients with myelodysplastic syndromes

Journal of Interferon and Cytokine Research

Volumn 18, Issue 10, 1998, Pages 871-877

  Reza, Samina ^a   Shetty, Vilasini ^a   Dar, Saleem ^a   Qawi, Huma ^a   Raza, Azra ^a  

^a RUSH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; DEXAMETHASONE; PENTOXIFYLLINE; TUMOR NECROSIS FACTOR ALPHA;

ANXIETY NEUROSIS; ARTICLE; BONE MARROW BIOPSY; CLINICAL ARTICLE; COMBINATION CHEMOTHERAPY; CYTOKINE PRODUCTION; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; EUPHORIA; GASTROINTESTINAL TOXICITY; HUMAN; MUSCLE WEAKNESS; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; TENDINITIS; WEIGHT GAIN;

EUPHORIA;

EID: 0031740061     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.1998.18.871     Document Type: Article

References (24)

1. KANTARJIAN, H.M., O'BRIEN, S., ANERLINI, P., and TALPAZ, M. (1996). Treatment of chronic myelogenous leukemia: current status and investigational options. Blood 87, 3069-3081.
2. MANDELLI, F., DIVERIO, D., AVVISATI, G., LUCIANNO, A., BARBUI, T., BERNASCONI, C., et al. (1997). Molecular remission in PML/RAR α-positive acute promyelocytic leukemia by combined All-trans retinoic acid and idarubicin (AIDA) therapy. Blood 90, 1014-1021.
3. HEYMAN, M.R. (1991). Recent advances in biology and treatment of myelodysplasia. Curr. Opin. Oncol. 3, 44-53.
4. ANDERSEN, J.E., APPELBAUM, F.R., SEHICH, G., GOOLEY, T., ANASEETI, C., BENSINGER, W.I., BRYANT, E., BUCKNER, C.D., CHAUNCEY, T.R., CHIFT, R.A., DONEY, K., FLOWERS, M., HANSEN, J.A., MARTIN, P.J., MATHEWS, D.C., SANDERS, J.E., SHULMAN, H., SULLIVAN, K.M., WITHERSPOON, R.P., and STORB, R. (1996). Allogeneic marrow transplantation for refractory anemia: a comparison of two preoperative regimens and analysis of prognostic factors. Blood 87, 51-58.
5. RAZA, A., MUNDLE, S., SHETTY, V., ALVI, S., CHOPRA, H., DAR, S., VENUGOPAL, P., BOROK, R., GEZER, S., SHOWEL, J., ROBIN, E., RIFKIN, S., ALSTON, D., HERNANDEZ, B., and GREGORY, S. (1996). Novel insights into the biology of myelodysplastic syndromes: excessive apoptosis and the role of cytokines. Int. J. Hematol. 63, 265-278.
6. RAZA, A., MUNDLE, S., SHETTY, V., ALVI, S., CHOPRA, H., SPAN, L., PARCHARIDOU, A., DAR, S., VENUGOPAL, P., BOROK, R., GEZER, S., SHOWEL, J., LOEW, J., ROBIN, RIFKIN, S., ALSTON, D., HERNANDEZ, B., SHAH, R., KAIZER, H., and GREGORY, S. (1996). A paradigm shift in myelodysplastic syndromes. Leukemia 10, 1648-1652.
7. RAZA, A., MUNDLE, S., IFTIKHAR, A., GREGORY, S., MARCUS, B., KHAN, Z., ALVI, S., SHETTY, V., DAMERON, S., WRIGHT, V., ADLER, S., LOEW, J., SCHOTT, S., ALI, N., and PREISLER, H. (1995). Simultaneous assessment of cell kinetics and programmed cell death in bone marrow biopsies of myelodysplastics reveals extensive apoptosis as the probable basis for ineffective hematopoiesis. Am. J. Hematol. 48, 143-154.
8. RAZA, A., ALVI, S., BROADY-ROBINSON, L., SHOWEL, M., CARTLIDGE, J., MUNDLE, S.D., SHETTY, V., BOROK, R.Z., DAR, S.E., CHOPRA, H.K., SPAN, L., PARCHARIDOU, A., HINES, C., GEZER, S., VENUGOPAL, P., LOEW, J., SHOWEL, J., ALSTON, D., HERNANDEZ, B., RIFKIN, S., ROBIN, E., SHAH, R., and GREGORY, S. (1997). Cell cycle kinetic studies in 68 patients with myelodysplastic syndromes following intravenous iodo- and/or bromodeoxyuridine. Exp. Hematol. 25, 530-535.
9. RAZA, A., GEZER, S., MUNDLE, S., GAO, X.-Z., ALVI, S., BOROK, R., RIFKIN, S., IFTIKHAR, A., SHETTY, V., PARCHARIDOU, A., LOEW, J., MARCUS, B., KHAN, Z., CHANEY, C., SHOWEL, J., GREGORY, S., and PREISLER, H. (1995). Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syndromes. Blood 86, 268-276.
10. SHETTY, V., MUNDLE, S., ALVI, S., SHOWEL, M., BROADY-ROBINSON, L., DAR, S., BOROK, R., SHOWEL, J., GREGORY, S., RIFKIN, S., GEZER, S., PARCHARIDOU, A., VENUGOPAL, P., SHAH, R., HERNANDEZ, B., KLEIN, M., ALSTON, D., ROBIN, E., DOMINQUEZ, C., and RAZA, A. (1996). Measurement of apoptosis, proliferation and three cytokines in 46 patients with myelodysplastic syndromes. Leuk. Res. 20, 891-900.
11. RAZA, A., GREGORY, S.A., and PREISLER, H.D. (1996). The myelodysplastic syndromes in 1996: complex stem cell disorders confounded by dual actions of cytokines. Leuk. Res. 20, 881-890.
12. MUNDLE, S.D., VENUGOPAL, P., PANDAY, D.V., BROADY-ROBINSON, L., GEZER, S., ROBIN, E.L., RIFKIN, S.R., KLEIN, M., ALSTON, D.E., HERNANDEZ, B.M., ROSI, D., ALVI, S., SHETTY, V.T., GREGORY, S.A., and RAZA, A. (1996). Indication of an involvement of interleukin-1β converting enzyme (ICE)-like protease in intramedullary apoptotic cell death in the bone marrows of patients with myelodysplastic syndromes (MDS). Blood 88, 2640-2647.
13. RAZA, A., VENUGOPAL, P., GEZER, S., GREGORY, S., DONG, L.M., LEURGANS, S., MUNDLE, S.D., SHETTY, V.T., ALVI, S., ALI, A., SPAN, L., DAR, S.E., HINES, C., HSU, W.-T., LOEW, J., BOROK, R.Z., HERNANDEZ, B., ROBIN, E., RIFKIN, S., ALSTON, D., SHAH, R., and PREISLER, H.D. (1998). Pilot study of pentoxifylline and ciprofloxacin with or without dexamethasone produces encouraging results in myelodysplastic syndromes. In: Acute Leukemias VII: Experimental Approaches and Novel Therapies. W. Hiddemann, T. Buchner, B. Wormann, J. Ritter, U. Creutzig, M. Keating, and W. Plunkett (eds.) Berlin, Heidelberg, New York: Springer-Verlag, pp. 42-51.
14. BENNETT, J.M., CATOVSKY, D., DANIEL, M.T., FLANDRIN, G., GALTON, D.A.G., GRALNICK, H.R., and SULTAN, C. (1982). Proposals for the classification of the myelodysplastic syndromes. Br. J. Haematol. 51, 189-199.
15. JASSEN, J.W.G., BUSCHLE, M., LAYTON, M., DREXLER, H.G., LYONS, J., and VAN DEN BERGHE, H. (1989). Clonal analysis of myelodysplastic syndromes: evidence of multipotential stem cell origin. Blood 73, 248-256.
16. BACKX, B., BROEDERS, L., TONW, I., and LOWENBERG, B. (1993). Blast colony-forming cells in myelodysplastic syndrome: decreased potential to generate erythroid precursors. Leukemia 7, 75-79.
17. OHMORI, M., OHMORI, S., VEDA, Y., YOSHIDA, Y., and OKUMA, M. (1991). Ineffective hemopoiesis in the myelodysplastic syndromes (MDS) as studied by daily in situ observations of colony-cluster formation. Int. J. Cell Cloning 9, 521-530.
18. + cells. Blood 85, 194-202.
19. THOMPSON, C.B., LINDSTEN, T., LEDBETTER, J.A., KUNKEL, S.L., YOUNG, H.A., EMERSON, S.G., LEIDEN, J.M., and JUNE, C.H. (1989). CD28 activation pathway regulates the production of multiple T-cell derived lymphokines/cytokines. Proc. Natl. Acad. Sci. USA 86, 1333-1337.
20. NATHAN, C.F. (1987). Secretory production of macrophages. J. Clin. Invest. 79, 319-326.
21. BACKX, B., BROEDERS, L., BOT, F.J., and LOWENBERG, B. (1991). Positive and negative effects of tumor necrosis factor on colony growth from highly purified normal marrow progenitors. Leukemia 5, 66-70.
22. SCHULTZ, J.C., and SHAHIDI, N.T. (1994). Detection of tumor necrosis factor-α in bone marrow, plasma and peripheral blood plasma from patients with aplastic anemia. Am. J. Hematol. 45, 32-38.
23. VERHOEF, G.E.G., SCHOUWER, P.de, CEUPPENS, J.L., VAN DAMME, J., GOOSSENS, W., and BOOGAERTS, M.A. (1992). Measurements of serum cytokine levels in patients with myelodysplastic syndromes. Leukemia 6, 1268-1272.
24. BURKE, P., GAO, X.-Z., RAZA, A., and PREISLER, H.D. (1996). The effects of cytokines and amifostine on the proliferation of MDS progenitor cells in vitro. American Society of Hematology 38th Annual Meeting. Blood 88, (Suppl 1) (Part 1 of 2), 93a (abstract 361).