메뉴 건너뛰기




Volumn 47, Issue 5, 2008, Pages 609-616

T lymphocytes in patients with primary vasculitis: Expansion of CD8+ T cells with the propensity to activate polymorphonuclear neutrophils

Author keywords

ANCA; CD11b; CD28; CD8; Microscopic polyangiitis; PMN; T cells; Vasculitis; WG

Indexed keywords

CD11B ANTIGEN; CD28 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; ENZYME ANTIBODY; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MYELOBLASTIN;

EID: 42949091796     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ken028     Document Type: Article
Times cited : (29)

References (63)
  • 1
    • 0035987347 scopus 로고    scopus 로고
    • Are ANCA pathogenic - oh yes they are
    • Falk RJ, Jennette JC. Are ANCA pathogenic - oh yes they are. J Am Soc Nephrol 2002;13:1977-9.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1977-1979
    • Falk, R.J.1    Jennette, J.C.2
  • 2
    • 4344717284 scopus 로고    scopus 로고
    • Auto-antibodies to human cytoplasmic antigens (ANCA) do not bind to polymorphonuclear neutrophils in whole blood
    • Abdel-Salam B, Iking-Konert C, Schneider M, Andrassy K, Hänsch GM. Auto-antibodies to human cytoplasmic antigens (ANCA) do not bind to polymorphonuclear neutrophils in whole blood. Kidney Int 2004;66:1009-17.
    • (2004) Kidney Int , vol.66 , pp. 1009-1017
    • Abdel-Salam, B.1    Iking-Konert, C.2    Schneider, M.3    Andrassy, K.4    Hänsch, G.M.5
  • 3
    • 0034050692 scopus 로고    scopus 로고
    • Pathogenesis of ANCA-associated systemic vasculitis
    • Harper L, Savage COS. Pathogenesis of ANCA-associated systemic vasculitis. J Pathol 2000;190:349-59.
    • (2000) J Pathol , vol.190 , pp. 349-359
    • Harper, L.1    Savage, C.O.S.2
  • 4
    • 31044449754 scopus 로고    scopus 로고
    • Pathogenesis of Wegener's granulomatosis: Current concepts
    • Sarrat P, Sneller MC. Pathogenesis of Wegener's granulomatosis: Current concepts. Expert Rev Mol Med 2005;13:1-19.
    • (2005) Expert Rev Mol Med , vol.13 , pp. 1-19
    • Sarrat, P.1    Sneller, M.C.2
  • 5
    • 29244463521 scopus 로고    scopus 로고
    • The pathogenesis of ANCA-associated vasculitides: Old hypotheses and new insights
    • Hänsch GM, Iking-Konert C, Andrassy K. The pathogenesis of ANCA-associated vasculitides: Old hypotheses and new insights. Clin Nephrol 2005;64:460-4.
    • (2005) Clin Nephrol , vol.64 , pp. 460-464
    • Hänsch, G.M.1    Iking-Konert, C.2    Andrassy, K.3
  • 6
    • 33746292135 scopus 로고    scopus 로고
    • Antineutrophil cytoplasmic antibodies
    • Bosch X, Guilabert A, Font J. Antineutrophil cytoplasmic antibodies. Lancet 2006;368:404-18.
    • (2006) Lancet , vol.368 , pp. 404-418
    • Bosch, X.1    Guilabert, A.2    Font, J.3
  • 7
    • 0025345612 scopus 로고
    • Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in Vitro
    • Falk R, Terrel R, Charles L, Jennette J. Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in Vitro. Proc, Natl Acad Sci USA 1990;87:4115-9.
    • (1990) Proc, Natl Acad Sci USA , vol.87 , pp. 4115-4119
    • Falk, R.1    Terrel, R.2    Charles, L.3    Jennette, J.4
  • 10
    • 0030779006 scopus 로고    scopus 로고
    • Antineutrophil cytoplasmic antibodies induce monocyte IL-8 release. Role of surface proteinase-3, alpha1-antitrypsin, and Fcgamma receptors
    • Ralston D, Marsh C, Lowe M, Wewers M. Antineutrophil cytoplasmic antibodies induce monocyte IL-8 release. Role of surface proteinase-3, alpha1-antitrypsin, and Fcgamma receptors. J Clin Invest 1997;100:1416-24.
    • (1997) J Clin Invest , vol.100 , pp. 1416-1424
    • Ralston, D.1    Marsh, C.2    Lowe, M.3    Wewers, M.4
  • 11
    • 25644459315 scopus 로고    scopus 로고
    • Anti-proteinase antibodies (c-ANCA) prime CD14-depedent leukocyte activation
    • Hatter K, van Burck S, Bickenbach A et al. Anti-proteinase antibodies (c-ANCA) prime CD14-depedent leukocyte activation. J Leukoc Biol 2005;78:992-1000.
    • (2005) J Leukoc Biol , vol.78 , pp. 992-1000
    • Hatter, K.1    van Burck, S.2    Bickenbach, A.3
  • 12
    • 0027932468 scopus 로고
    • Neutrophil activation in vitro and in vivo in Wegener's granulomatosis
    • Brouwer E, Hultema MG, Mulder AHL et al. Neutrophil activation in vitro and in vivo in Wegener's granulomatosis. Kidney Int 1994;45:1120-31.
    • (1994) Kidney Int , vol.45 , pp. 1120-1131
    • Brouwer, E.1    Hultema, M.G.2    Mulder, A.H.L.3
  • 13
    • 0028307148 scopus 로고
    • Activated neutrophils express proteinase 3 on their plasma membrane in vitro and in vivo
    • Csernok E, Ernst M, Schmitt W, Bainton DF, Gross WL. Activated neutrophils express proteinase 3 on their plasma membrane in vitro and in vivo. Clin Exp Immunol 1994;95:244-50.
    • (1994) Clin Exp Immunol , vol.95 , pp. 244-250
    • Csernok, E.1    Ernst, M.2    Schmitt, W.3    Bainton, D.F.4    Gross, W.L.5
  • 14
    • 0031826477 scopus 로고    scopus 로고
    • Leucocyte membrane expression of proteinase 3 correlates with disease activity in patients with Wegener's granulomatosis
    • Müllier-Kabold AC, Kallenberg CG, Tervaert JW. Leucocyte membrane expression of proteinase 3 correlates with disease activity in patients with Wegener's granulomatosis. Br J Rheumatol 1998;37:901-7.
    • (1998) Br J Rheumatol , vol.37 , pp. 901-907
    • Müllier-Kabold, A.C.1    Kallenberg, C.G.2    Tervaert, J.W.3
  • 15
    • 0031801514 scopus 로고    scopus 로고
    • Autoantibodies to polymorphonuclear neutrophil elastase do not inhibit but enhance elastase activity
    • Morcos M, Zimmermann F, Radsak M et al. Autoantibodies to polymorphonuclear neutrophil elastase do not inhibit but enhance elastase activity. Am J Kidney Dis 1998;31:978-85.
    • (1998) Am J Kidney Dis , vol.31 , pp. 978-985
    • Morcos, M.1    Zimmermann, F.2    Radsak, M.3
  • 16
    • 0030059306 scopus 로고    scopus 로고
    • Circulating leukocyte integrin expression in Wegener's granulomatosis
    • Haller H, Eichhom J, Pieper K, Göbel U, Luft F. Circulating leukocyte integrin expression in Wegener's granulomatosis. J Am Soc Nephrol 1996;7:40-8.
    • (1996) J Am Soc Nephrol , vol.7 , pp. 40-48
    • Haller, H.1    Eichhom, J.2    Pieper, K.3    Göbel, U.4    Luft, F.5
  • 17
    • 0031736098 scopus 로고    scopus 로고
    • Are circulating neutrophils intravascularly activated in patients with anti-neutrophil cytoplasmic antiloody (ANCA)-associated vasulitides?
    • Müller-Kobold AC, Mesander G, Stegeman CA, Kallenberg CG, Tervaert JW. Are circulating neutrophils intravascularly activated in patients with anti-neutrophil cytoplasmic antiloody (ANCA)-associated vasulitides? Clin Exp Immunol 1998;114: 491-9.
    • (1998) Clin Exp Immunol , vol.114 , pp. 491-499
    • Müller-Kobold, A.C.1    Mesander, G.2    Stegeman, C.A.3    Kallenberg, C.G.4    Tervaert, J.W.5
  • 18
    • 29244470942 scopus 로고    scopus 로고
    • Microarray expression analysis of systemic lupus erythematodes and ANCA vasculitis patient leukocytes revealed disease specific gene expression signatures
    • Alcorta D, Barbes DA, Dooley M et al. Microarray expression analysis of systemic lupus erythematodes and ANCA vasculitis patient leukocytes revealed disease specific gene expression signatures. Kid Blood Press Res 2005;28:171.
    • (2005) Kid Blood Press Res , vol.28 , pp. 171
    • Alcorta, D.1    Barbes, D.A.2    Dooley, M.3
  • 19
    • 0032953839 scopus 로고    scopus 로고
    • Expression of major histocompatibility class II antigens on polymorphonuclear neutrophils in patients with Wegener's granulomatosis
    • Hänsch GM, Radsak M, Wagner C et al. Expression of major histocompatibility class II antigens on polymorphonuclear neutrophils in patients with Wegener's granulomatosis. Kidney Int 1999;55:1181-8.
    • (1999) Kidney Int , vol.55 , pp. 1181-1188
    • Hänsch, G.M.1    Radsak, M.2    Wagner, C.3
  • 20
    • 0035187247 scopus 로고    scopus 로고
    • Polymorphonuclear neutrophils in Wegener's granulomatosis acquire characteristics of antigen presenting cells
    • Iking-Konert C, Vogt S, Radsak M, Wagner C, Hansch GM, Andrassy K. Polymorphonuclear neutrophils in Wegener's granulomatosis acquire characteristics of antigen presenting cells. Kidney Int 2001;60:2247-62.
    • (2001) Kidney Int , vol.60 , pp. 2247-2262
    • Iking-Konert, C.1    Vogt, S.2    Radsak, M.3    Wagner, C.4    Hansch, G.M.5    Andrassy, K.6
  • 21
    • 0027197997 scopus 로고
    • Induction of MHG class II on human polymorphonuclear neutrophils by granulocyte/macrophage colony-stimulating factor, IFN-gamma, and IL-3
    • Gosselin EJ, Wardwell K, Rigby WF, Guyre PM. Induction of MHG class II on human polymorphonuclear neutrophils by granulocyte/macrophage colony-stimulating factor, IFN-gamma, and IL-3. J Immunol 1993;151:1482-90.
    • (1993) J Immunol , vol.151 , pp. 1482-1490
    • Gosselin, E.J.1    Wardwell, K.2    Rigby, W.F.3    Guyre, P.M.4
  • 22
    • 17544399960 scopus 로고    scopus 로고
    • In vivo induction of HLA-DR on human neutrophils in patients treated with interferon-γ
    • Reinisch W, Tillinger W, Lichtenberger C et al. In vivo induction of HLA-DR on human neutrophils in patients treated with interferon-γ. Blood 1996;87:3068.
    • (1996) Blood , vol.87 , pp. 3068
    • Reinisch, W.1    Tillinger, W.2    Lichtenberger, C.3
  • 23
    • 0034529299 scopus 로고    scopus 로고
    • Radsak M, Iking-Konert C, Stegmaier 8, Andrassy K, Hänech GM. Polymorpho-nuclear neutrophils (PMN) as accessory cells for T-cell activation: MHC class II restricted antigen-dependent induction of T-cell proliferation. Immunology 2000;101:521-30.
    • Radsak M, Iking-Konert C, Stegmaier 8, Andrassy K, Hänech GM. Polymorpho-nuclear neutrophils (PMN) as accessory cells for T-cell activation: MHC class II restricted antigen-dependent induction of T-cell proliferation. Immunology 2000;101:521-30.
  • 24
    • 2342495351 scopus 로고    scopus 로고
    • Interferon-gamma activation of polymorphonuclear neutrophil function
    • Ellis TN, Beaman BL. Interferon-gamma activation of polymorphonuclear neutrophil function. Immunology 2004;112:2-12.
    • (2004) Immunology , vol.112 , pp. 2-12
    • Ellis, T.N.1    Beaman, B.L.2
  • 25
    • 0028940102 scopus 로고
    • Antineutrophil cytoplasmic autoantibodies, autoantigens, and systemic vasculitis
    • Gross WL, Csemok E, Helmchen U. Antineutrophil cytoplasmic autoantibodies, autoantigens, and systemic vasculitis. APMIS 1995;103:81-97.
    • (1995) APMIS , vol.103 , pp. 81-97
    • Gross, W.L.1    Csemok, E.2    Helmchen, U.3
  • 26
    • 0034468049 scopus 로고    scopus 로고
    • What you should know about PR3-ANCA. Evidence for the role of T cells in the pathogenesis of systemic vasculitis
    • Clayton AR, Savage CO. What you should know about PR3-ANCA. Evidence for the role of T cells in the pathogenesis of systemic vasculitis. Arthritis Res 2000;2:260-2.
    • (2000) Arthritis Res , vol.2 , pp. 260-262
    • Clayton, A.R.1    Savage, C.O.2
  • 28
    • 22344436790 scopus 로고    scopus 로고
    • Off balance: T-cells in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides
    • Lamprecht P. Off balance: T-cells in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides. Clin Exp Immunol 2005;141:201-10.
    • (2005) Clin Exp Immunol , vol.141 , pp. 201-210
    • Lamprecht, P.1
  • 29
    • 1642545105 scopus 로고    scopus 로고
    • European Vasculitis Study GroupTreatment of refractory Wegener's granulomatosis with antithymocyte globulin(ATG): An open study in 15 patients
    • Schmitt WH, Hagen EC, Neumann I, Nowack R, Flores-Suarez LF, van der Woude FJ. European Vasculitis Study GroupTreatment of refractory Wegener's granulomatosis with antithymocyte globulin(ATG): An open study in 15 patients. Kidney Int 2004;65:1440-8.
    • (2004) Kidney Int , vol.65 , pp. 1440-1448
    • Schmitt, W.H.1    Hagen, E.C.2    Neumann, I.3    Nowack, R.4    Flores-Suarez, L.F.5    van der Woude, F.J.6
  • 30
    • 0038188664 scopus 로고    scopus 로고
    • Shortening of telomeres: Evidence for replicative senescence of T cells derived from patients with Wegener's granulomalosis
    • Vogt S, Iking-Konert C, Hug F, Andrassy K, Hansch GM. Shortening of telomeres: Evidence for replicative senescence of T cells derived from patients with Wegener's granulomalosis. Kidney Int 2003;63:2144-51.
    • (2003) Kidney Int , vol.63 , pp. 2144-2151
    • Vogt, S.1    Iking-Konert, C.2    Hug, F.3    Andrassy, K.4    Hansch, G.M.5
  • 31
  • 32
    • 33747858975 scopus 로고    scopus 로고
    • Persistent expansion of CD4+ effector memory T cells in Wegener's granulomatosis
    • Abdulahad WH, van der Geld YM, Stageman CA, Kallenberg CG. Persistent expansion of CD4+ effector memory T cells in Wegener's granulomatosis. Kidney Int 2006;70:938-47.
    • (2006) Kidney Int , vol.70 , pp. 938-947
    • Abdulahad, W.H.1    van der Geld, Y.M.2    Stageman, C.A.3    Kallenberg, C.G.4
  • 33
    • 22544479983 scopus 로고    scopus 로고
    • Receptors for complement, C3 on T-lymphocytes: Relics of evolution or functional molecules?
    • Wagner C, Hänsch M. Receptors for complement, C3 on T-lymphocytes: relics of evolution or functional molecules? Mol Immunol 2006;43:22-30.
    • (2006) Mol Immunol , vol.43 , pp. 22-30
    • Wagner, C.1    Hänsch, M.2
  • 34
    • 0026708995 scopus 로고
    • CD11b (Mac-1): A marker for CD8+ cytotoxic T cell activation and memory in virus infection
    • McFarland HI, Nahill SR, Maciaszek JW, Welsh RM. CD11b (Mac-1): A marker for CD8+ cytotoxic T cell activation and memory in virus infection. J Immunol 1992;149:1326-33.
    • (1992) J Immunol , vol.149 , pp. 1326-1333
    • McFarland, H.I.1    Nahill, S.R.2    Maciaszek, J.W.3    Welsh, R.M.4
  • 35
    • 0035067514 scopus 로고    scopus 로고
    • CD11b expression as a marker to distinguish between recently activated effector CD8(+) T cells and memory cells
    • Christensen JE, Andreasen SO, Christensen JP, Thomson AR. CD11b expression as a marker to distinguish between recently activated effector CD8(+) T cells and memory cells. Int Immunol 2001;13:593-600.
    • (2001) Int Immunol , vol.13 , pp. 593-600
    • Christensen, J.E.1    Andreasen, S.O.2    Christensen, J.P.3    Thomson, A.R.4
  • 36
    • 0035863819 scopus 로고    scopus 로고
    • CD11b expression identifies CD8+CD28+ T lymphocytes with phenotype and function of both naive/memory and effector cells
    • Fiorentini S, Licenziati S, Alessandri G et al. CD11b expression identifies CD8+CD28+ T lymphocytes with phenotype and function of both naive/memory and effector cells. J Immunol 2001;166:900-7.
    • (2001) J Immunol , vol.166 , pp. 900-907
    • Fiorentini, S.1    Licenziati, S.2    Alessandri, G.3
  • 37
    • 0028150660 scopus 로고
    • Birmingham vasculitis activity score (BVAS) in systemic necrotizing vasculitis
    • Luqmani R, Bacon P, Moots R et al. Birmingham vasculitis activity score (BVAS) in systemic necrotizing vasculitis. Q J Med 1994;87:671-8.
    • (1994) Q J Med , vol.87 , pp. 671-678
    • Luqmani, R.1    Bacon, P.2    Moots, R.3
  • 38
    • 0028158243 scopus 로고    scopus 로고
    • Jennette JC, Falk RJ, Andrassy K et al. Nomenclature of systemic vasculitis: The proposal of an international consensus conference. Arthritis Rheum 1994;37:187-92.
    • Jennette JC, Falk RJ, Andrassy K et al. Nomenclature of systemic vasculitis: The proposal of an international consensus conference. Arthritis Rheum 1994;37:187-92.
  • 39
    • 0025183423 scopus 로고
    • The American College of Rheumatology 1990 Criteria for the classification of Wegener's granulomatosis
    • Leavitt RY, Fauci AS, Bloch DA et al. The American College of Rheumatology 1990 Criteria for the classification of Wegener's granulomatosis. Arthritis Rheum 1990;33:1101-7.
    • (1990) Arthritis Rheum , vol.33 , pp. 1101-1107
    • Leavitt, R.Y.1    Fauci, A.S.2    Bloch, D.A.3
  • 40
    • 0028334702 scopus 로고
    • Influence of disease manifestation and antineutrophil cytoplasmic antibody titer on the response to pulse cyclophosphamide therapy in patients with Wegener's granulomatosis
    • Reinhold-Keller E, Kekow J, Schnabel A et al. Influence of disease manifestation and antineutrophil cytoplasmic antibody titer on the response to pulse cyclophosphamide therapy in patients with Wegener's granulomatosis. Arthritis Rheum 1994;37:919-24.
    • (1994) Arthritis Rheum , vol.37 , pp. 919-924
    • Reinhold-Keller, E.1    Kekow, J.2    Schnabel, A.3
  • 41
    • 0035152304 scopus 로고    scopus 로고
    • Development and validation of a disease extent index for Wegener's granulomatosis
    • de Groot K, Gross WL, Herlyn K, Reinhold-Keller E. Development and validation of a disease extent index for Wegener's granulomatosis. Clin Nephrol 2001;55:31-8.
    • (2001) Clin Nephrol , vol.55 , pp. 31-38
    • de Groot, K.1    Gross, W.L.2    Herlyn, K.3    Reinhold-Keller, E.4
  • 43
    • 0031718132 scopus 로고    scopus 로고
    • Costimulatory molecules in Wegner's granulomatosis (WG): Lack of expression of CD28 and preferential up-regulation of its ligands B7-1 (CD80) and B-2 (CD86) on T-cells
    • Moosig F, Czemok E, Wang G, Gross WL. Costimulatory molecules in Wegner's granulomatosis (WG): Lack of expression of CD28 and preferential up-regulation of its ligands B7-1 (CD80) and B-2 (CD86) on T-cells. Clin Exp Immunol 1998;114: 113-8.
    • (1998) Clin Exp Immunol , vol.114 , pp. 113-118
    • Moosig, F.1    Czemok, E.2    Wang, G.3    Gross, W.L.4
  • 44
    • 20144388308 scopus 로고    scopus 로고
    • Abnormalities of CD4T cell subpopulations in ANCA-associated vasculitis
    • Marinaki S, Neumann I, Kalsch AI et al. Abnormalities of CD4T cell subpopulations in ANCA-associated vasculitis. Clin Exp Immunol 2005;140:181-9.
    • (2005) Clin Exp Immunol , vol.140 , pp. 181-189
    • Marinaki, S.1    Neumann, I.2    Kalsch, A.I.3
  • 45
    • 0028278370 scopus 로고
    • Anti-neutrophil cytoplasmic antibodies engage and activate human neutrophils, via Fc gamma RIIa
    • Porges A, Redecha P, Kimberly W et al. Anti-neutrophil cytoplasmic antibodies engage and activate human neutrophils, via Fc gamma RIIa. J Immunol 1994;153:1271-80.
    • (1994) J Immunol , vol.153 , pp. 1271-1280
    • Porges, A.1    Redecha, P.2    Kimberly, W.3
  • 46
    • 0031004487 scopus 로고    scopus 로고
    • Apoptosis in resolution of inflammation
    • Savill J. Apoptosis in resolution of inflammation. J Leukoc Biol 1997;61:375-80.
    • (1997) J Leukoc Biol , vol.61 , pp. 375-380
    • Savill, J.1
  • 48
    • 0030691102 scopus 로고    scopus 로고
    • Tissue injury in neutrophilic inflammation
    • Dallegri F, Ottonello L. Tissue injury in neutrophilic inflammation. InflammRes 1997;46:382-91.
    • (1997) InflammRes , vol.46 , pp. 382-391
    • Dallegri, F.1    Ottonello, L.2
  • 49
    • 0141576701 scopus 로고    scopus 로고
    • Edwards SW, Moulding DA, Derouet R, Moots RJ. Regulation of neutrophil apoptosis. In: Cassatella M (eA.), The neutrophil: an emerging regulator of inflammatory and immune response. Chem Immunol Allergy 2003;83:204-24; Basel: Karger.
    • Edwards SW, Moulding DA, Derouet R, Moots RJ. Regulation of neutrophil apoptosis. In: Cassatella M (eA.), The neutrophil: an emerging regulator of inflammatory and immune response. Chem Immunol Allergy 2003;83:204-24; Basel: Karger.
  • 50
    • 0141465109 scopus 로고    scopus 로고
    • Expression of MHC class II antigen and coreceptor molecules in polymorphonuclear neutrophils
    • Hänsch GM, Wagner C. Expression of MHC class II antigen and coreceptor molecules in polymorphonuclear neutrophils. Chem Immunol Allergy 2003;83:45-63.
    • (2003) Chem Immunol Allergy , vol.83 , pp. 45-63
    • Hänsch, G.M.1    Wagner, C.2
  • 51
    • 0031701541 scopus 로고    scopus 로고
    • Expanded T cell populations in patients with Wegener's granulomatosis: Characteristics and correlates with disease activity
    • Giscombe R, Nityanand S, Lewin N, Grunewald J, Lefvert AK. Expanded T cell populations in patients with Wegener's granulomatosis: characteristics and correlates with disease activity. J Clin Immunol 1998;18:404-13.
    • (1998) J Clin Immunol , vol.18 , pp. 404-413
    • Giscombe, R.1    Nityanand, S.2    Lewin, N.3    Grunewald, J.4    Lefvert, A.K.5
  • 52
    • 2642680076 scopus 로고    scopus 로고
    • Active Wegener's granulomatosis is associated with HLA-DR+ CD4+ T cells exhibiting an unbalanced Th1-type T cell cytokine pattern: Reversal with IL-10
    • Ludviksson BR, Sneller MC, Chua KS et al. Active Wegener's granulomatosis is associated with HLA-DR+ CD4+ T cells exhibiting an unbalanced Th1-type T cell cytokine pattern: Reversal with IL-10. J Immunol 1998;160:3602-9.
    • (1998) J Immunol , vol.160 , pp. 3602-3609
    • Ludviksson, B.R.1    Sneller, M.C.2    Chua, K.S.3
  • 53
    • 0036097722 scopus 로고    scopus 로고
    • Peripheral blood and granuloma CD4(+)CD28(-) T cells are a major source of interferon-gamma and tumor necrosis factor-alpha in Wegener's granulomatosis
    • Komocsi A, Lamprecht P, Csernok E et al. Peripheral blood and granuloma CD4(+)CD28(-) T cells are a major source of interferon-gamma and tumor necrosis factor-alpha in Wegener's granulomatosis. Am J Pathol 2002;160:1717-24.
    • (2002) Am J Pathol , vol.160 , pp. 1717-1724
    • Komocsi, A.1    Lamprecht, P.2    Csernok, E.3
  • 54
    • 14144254679 scopus 로고    scopus 로고
    • District tumour necrosis factor alpha, interferon gamma, interleukin 10, and cytotoxic T cell antigen 4 gene polymorphisms in disease occurrence and end stage renal disease in Wegener's granulomatosis
    • Spriewald BM, Witzke O, Wassmuth R et al. District tumour necrosis factor alpha, interferon gamma, interleukin 10, and cytotoxic T cell antigen 4 gene polymorphisms in disease occurrence and end stage renal disease in Wegener's granulomatosis. Ann Rheum Dis 2005;64:457-61.
    • (2005) Ann Rheum Dis , vol.64 , pp. 457-461
    • Spriewald, B.M.1    Witzke, O.2    Wassmuth, R.3
  • 55
    • 0034811089 scopus 로고    scopus 로고
    • CD28 negative T-cells are enriched in granulomatous lesions of the respiratory tract in Wegener's granulomatosis
    • Lamprecht P, Moosig F et al. CD28 negative T-cells are enriched in granulomatous lesions of the respiratory tract in Wegener's granulomatosis. Thorax 2001;56:751-7.
    • (2001) Thorax , vol.56 , pp. 751-757
    • Lamprecht, P.1    Moosig, F.2
  • 56
    • 0037675815 scopus 로고    scopus 로고
    • Differences in CCR5 expression on peripheral blood CD4+CD28- T-cells and in granulomatous lesions between localized and generalized Wegener's granulomatosis
    • Lamprecht P, Bruhl H, Csernok E et al. Differences in CCR5 expression on peripheral blood CD4+CD28- T-cells and in granulomatous lesions between localized and generalized Wegener's granulomatosis. Clin Immunol 2003;108:1-7.
    • (2003) Clin Immunol , vol.108 , pp. 1-7
    • Lamprecht, P.1    Bruhl, H.2    Csernok, E.3
  • 57
    • 0028077538 scopus 로고
    • T cell reactivity to proteinase 3 and myeloperoxidase in patients with Wegener's granulomatosis (WG)
    • Brouwer E, Stegeman C, Huitema M et al. T cell reactivity to proteinase 3 and myeloperoxidase in patients with Wegener's granulomatosis (WG). Clin Exp Immunol 1994;98:448-53.
    • (1994) Clin Exp Immunol , vol.98 , pp. 448-453
    • Brouwer, E.1    Stegeman, C.2    Huitema, M.3
  • 58
    • 0036068953 scopus 로고    scopus 로고
    • In vitro cytokine production and proliferation of T cells from patients with anti-proteinase 3- and antimyeloperoxidase-associated vasculitis, in response to proteinase 3 and myeloperoxidase
    • Pope ER, Franssen CF, Limburg PC, Huitema MG, Kallenberg CG, Tervaert JW. In vitro cytokine production and proliferation of T cells from patients with anti-proteinase 3- and antimyeloperoxidase-associated vasculitis, in response to proteinase 3 and myeloperoxidase. Arthritis Rheum 2002;46:1894-904.
    • (2002) Arthritis Rheum , vol.46 , pp. 1894-1904
    • Pope, E.R.1    Franssen, C.F.2    Limburg, P.C.3    Huitema, M.G.4    Kallenberg, C.G.5    Tervaert, J.W.6
  • 59
    • 0034536134 scopus 로고    scopus 로고
    • In vitro T lymphocyte responses to proteinase 3 (PR3) and linear peptides of PR3 in patients with Wegener's granulomatosis (WG)
    • van der Geld YM, Huitema MG, Franssen CF, van der Zee R, Limburg PC, Kallenberg CG. In vitro T lymphocyte responses to proteinase 3 (PR3) and linear peptides of PR3 in patients with Wegener's granulomatosis (WG). Clin Exp Immunol 2000;122:504-13.
    • (2000) Clin Exp Immunol , vol.122 , pp. 504-513
    • van der Geld, Y.M.1    Huitema, M.G.2    Franssen, C.F.3    van der Zee, R.4    Limburg, P.C.5    Kallenberg, C.G.6
  • 60
    • 0346098116 scopus 로고    scopus 로고
    • Frequency of proteinase 3 (PR3)-specific autoreactive T cells determined by cytokine flow cytometry in Wegener's granulomatosis
    • Winek J, Mueller A, Csernok E, Gross WL. Lamprecht P. Frequency of proteinase 3 (PR3)-specific autoreactive T cells determined by cytokine flow cytometry in Wegener's granulomatosis. J Autoimmun 2004;22:79-85.
    • (2004) J Autoimmun , vol.22 , pp. 79-85
    • Winek, J.1    Mueller, A.2    Csernok, E.3    Gross, W.L.4    Lamprecht, P.5
  • 61
    • 0035063236 scopus 로고    scopus 로고
    • The complement receptor 3, CR3 (CD11b/CD18) on T lymphocytes: Activation-dependent up-regulation and regulatory function
    • Wagner C, Hänsch GM, Stegmaier S, Denefleh B, Hug F, Schoels M. The complement receptor 3, CR3 (CD11b/CD18) on T lymphocytes: activation-dependent up-regulation and regulatory function. Eur J Immunol 2001;31:1173-80.
    • (2001) Eur J Immunol , vol.31 , pp. 1173-1180
    • Wagner, C.1    Hänsch, G.M.2    Stegmaier, S.3    Denefleh, B.4    Hug, F.5    Schoels, M.6
  • 62
    • 20344379893 scopus 로고    scopus 로고
    • CD28 extinction in human T cells: Altered functions and the program of T-cell senescence
    • Vallejo AN. CD28 extinction in human T cells: Altered functions and the program of T-cell senescence. Immunol Rev 2005;205:158-69.
    • (2005) Immunol Rev , vol.205 , pp. 158-169
    • Vallejo, A.N.1
  • 63
    • 0031005523 scopus 로고    scopus 로고
    • Activation of human T cells by major histocompatability complex class II expressing neutrophils: Proliferation in the presence of superantigen, but not tetanus toxoid
    • Fanger NA, Liu C, Guyre PM et al. Activation of human T cells by major histocompatability complex class II expressing neutrophils: proliferation in the presence of superantigen, but not tetanus toxoid. Blood 1997;89:4128-35.
    • (1997) Blood , vol.89 , pp. 4128-4135
    • Fanger, N.A.1    Liu, C.2    Guyre, P.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.