A simple and convenient synthesis of 4-methyl-3-nitro-2-trihalomethyl-2H-chromenes from N-unsubstituted imines of 2-hydroxyacetophenones and trichloro(trifluoro)ethylidene nitromethanes

Tetrahedron

Volumn 64, Issue 22, 2008, Pages 5055-5060

  Korotaev, Vladislav Yu ^a   Sosnovskikh, Vyacheslav Ya ^a   Kutyashev, Igor B ^a   Barkov, Alexey Yu ^a   Matochkina, Evgeniya G ^b   Kodess, Mikhail I ^b  

^a URAL FEDERAL UNIVERSITY   (Russian Federation)

^b INSTITUTE OF ORGANIC SYNTHESIS   (Russian Federation)

Author keywords

2 Hydroxyacetophenones imines; 4 Methyl 2H chromenes; Michael addition; Nitroalkenes; Trihalomethylated compounds

Indexed keywords

1,1,1 TRICHLORO 3 NITRO N[1 (2 HYDROXY 4 METHOXYPHENYL)ETHYLIDENE]PROPAN 2 AMINE; 1,1,1 TRICHLORO 3 NITRO N[1 (2 HYDROXY 5 METHYLPHENYL)ETHYLIDENE]PROPAN 2 AMINE; 1,1,1 TRICHLORO 3 NITRO N[1 (2 HYDROXYPHENYL)ETHYLIDENE]PROPAN 2 AMINE; 1,1,1 TRICHLORO 3 NITRO N[1 (4,6 DIMETHYL 2 HYDROXYYPHENYL)ETHYLIDENE]PROPAN 2 AMINE; 1,1,1 TRICHLORO 3 NITRO N[1 (5 CHLORO 2 HYDROXYYPHENYL)ETHYLIDENE]PROPAN 2 AMINE; 1,1,1 TRIFLUORO 3 NITRO N[1 (2 HYDROXYYPHENYL)ETHYLIDENE]PROPAN 2 AMINE; 1,1,1 TRIFLUORO 3 NITRO N[1 (4,6 DIMETHYL 2 HYDROXYYPHENYL)ETHYLIDENE]PROPAN 2 AMINE; 1,4 DIAZABICYCLO[2.2.2]OCTANE; 2 HYDROXY 4 METHYLACETOPHENONE IMINE; 2 HYDROXY 5 METHYLACETOPHENONE IMINE; 2 HYDROXYACETOPHENONE IMINE; 3,5 DIBROMO 2 HYDROXYACETOPHENONE IMINE; 4 METHYL 3 NITRO 2 (TRICHLOROMETHYL) 2H CHROMENE; 4 METHYL 3 NITRO 2 (TRIFLUOROMETHYL) 2H CHROMENE; 4,6 DIMETHYL 2 HYDROXYACETOPHENONE IMINE; 4,6 DIMETHYL 3 NITRO 2 (TRICHLOROMETHYL) 2H CHROMENE; 4,6 DIMETHYL 3 NITRO 2 (TRICHLOROMETHYL)CHROMAN 4 AMINE; 4,6 DIMETHYL 3 NITRO 2 (TRIFLUOROMETHYL) 2H CHROMENE; 5 CHLORO 2 HYDROXYACETOPHENONE IMINE; 7 METHOXY 4 METHYL 3 NITRO 2 (TRICHLOROMETHYL) 2H CHROMENE; ACETOPHENONE DERIVATIVE; CHROMENE DERIVATIVE; IMINE; NITROMETHANE;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; MICHAEL ADDITION; PRIORITY JOURNAL; SUBSTITUTION REACTION;

TRIFLUORO;

EID: 42749097242     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.03.065     Document Type: Article

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