Efficient and chemoselective access to 3-(chloromethyl)coumarins via direct cyclisation of unprotected Baylis-Hillman adducts

Synthesis

Volumn , Issue 4, 2003, Pages 531-534

  Kaye, Perry T ^a   Musa, Musiliyu A ^a   Nocanda, Xolani W ^a  

^a RHODES UNIVERSITY   (South Africa)

Author keywords

2H 1 benzopyran 2 ones; Baylis Hillman reaction; Coumarins; Heterocycles; Synthesis

Indexed keywords

ALDEHYDES; CATALYSTS; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

CHEMOSELECTIVE ACCESS;

REACTION KINETICS;

1,4 DIAZABICYCLO[2.2.2]OCTANE; 3 (CHLOROMETHYL)COUMARIN DERIVATIVE; ACRYLIC ACID DERIVATIVE; COUMARIN DERIVATIVE; HETEROCYCLIC COMPOUND; SALICYLALDEHYDE; TERT BUTYLACRYLATE; UNCLASSIFIED DRUG;

ARTICLE; BAYLIS HILLMAN REACTION; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CYCLIZATION; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0037240873     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-37655     Document Type: Article

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