Design and construction of a microcoil NMR probe for the routine analysis of 20-μL samples

Concepts in Magnetic Resonance Part B: Magnetic Resonance Engineering

Volumn 33, Issue 1, 2008, Pages 1-8

  Henry, Ian D ^a   Park, Gregory H J ^a   Kc, Ravi ^a   Tobias, Brian ^b   Raftery, Daniel ^a  

^a PURDUE UNIVERSITY   (United States)

^b PFIZER INC   (United States)

Author keywords

1H NMR; HF; Laser etching; Microcoils; Transmission lines

Indexed keywords

EID: 42749095200     PISSN: 15525031     EISSN: 1552504X     Source Type: Journal    
DOI: 10.1002/cmr.b.20101     Document Type: Article

References (39)

1. Olson DL, Lacey ME, Sweedler JV. 1998. The nanoliter niche - NMR detection for trace analysis and capillary separations. Anal Chem 70:257A-264A.
2. Webb AG. 2005. Microcoil nuclear magnetic resonance spectroscopy. J Pharm Biomed Anal 38:892-903.
3. Olson DL, Norcross JA, O'Neil-Johnson M, Molitor PF, Detlefsen DJ, Wilson AG, et al. 2004. Microflow NMR: concepts and capabilities. Anal Chem 76:2966-2974.
4. Hoult DI, Richards RE. 1976. Signal-to-noise ratio of nuclear magnetic-resonance experiment. J Magn Reson 24:71-85.
5. Olson DL, Peck TL, Webb AG, Magin RL, Sweedler JV. 1995. High-resolution microcoil H-1-NMR for mass-limited, nanoliter-volume samples. Science 270:1967-1970.
6. Jansma A, Chuan T, Albrecht RW, Olson DL, Peck TL, Geierstanger BH. 2005. Automated microflow NMR: routine analysis of five-microliter samples. Anal Chem 77:6509-6515.
7. Subramanian R, Lam MM, Webb AG. 1998. RF microcoil design for practical NMR of mass-limited samples. J Magn Reson 133:227-231.
8. Fisher G, Petucci C, MacNamara E, Raftery D. 1999. NMR probe for the simultaneous acquisition of multiple samples. J Magn Reson 138:160-163.
9. Zhang X, Sweedler JV, Webb AG. 2001. A probe design for the acquisition of homonuclear, heteronuclear, and inverse detected NMR spectra from multiple samples. J Magn Reson 153:254-258.
10. Hou T, MacNamara E, Raftery D. 1999. NMR analysis of multiple samples using parallel coils: improved performance using reference deconvolution and multi-dimensional methods. Anal Chim Acta 400:297-305.
11. Hou T, Smith J, MacNamara E, Macnaughtan M, Raftery D. 2001. Analysis of multiple samples using multiplex sample NMR: selective excitation and chemical shift imaging approaches. Anal Chem 73:2541-2546.
12. MacNamara E, Hou T, Fisher G, Williams S, Raftery D. 1999. Multiplex sample NMR: an approach to high-throughput NMR using a parallel coil probe. Anal Chim Acta 397:9-16.
13. Macnaughtan MA, Hou T, Xu J, Raftery D. 2003. High-throughput nuclear magnetic resonance analysis using a multiple coil flow probe. Anal Chem 75:5116-5123.
14. Wang H, Ciobanu L, Edison AS, Webb AG. 2004. An eight-coil high-frequency probehead design for high-throughput nuclear magnetic resonance spectroscopy. J Magn Reson 170:206-212.
15. Albert K. 2006. HPLC-NMR-coupling. Nachr Chem 54:428-432.
16. Djukovic D, Liu S, Henry I, Tobias B, Raftery D. 2006. Signal enhancement in HPLC/microcoil NMR using automated column trapping. Anal Chem 78:7154-7160.
17. Hentschel P, Krucker M, Grynbaum MD, Putzbach K, Bischoff R, Albert K. 2005. Determination of regulatory phosphorylation sites in nanogram amounts of a synthetic fragment of ZAP-70 using microprobe NMR and on-line coupled capillary HPLC-NMR. Magn Reson Chem 43:747-754.
18. Krucker M, Lienau A, Putzbach K, Grynbaum MD, Schuger P, Albert K. 2004. Hyphenation of capillary HPLC to microcoil H-1 NMR spectroscopy for the determination of tocopherol homologues. Anal Chem 76:2623-2628.
19. Lacey ME, Tan ZJ, Webb AG, Sweedler JV. 2001. Union of capillary high-performance liquid chromatography and microcoil nuclear magnetic resonance spectroscopy applied to the separation and identification of terpenoids. J Chromatogr A 922:139-149.
20. Putzbach K, Krucker M, Grynbaum MD, Hentschel P, Webb AG, Albert K. 2005. Hyphenation of capillary high-performance liquid chromatography to microcoil magnetic resonance spectroscopy - determination of various carotenoids in a small-sized spinach sample. J Pharm Biomed Anal 38:910-917.
21. Subramanian R, Kelley WP, Floyd PD, Tan ZJ, Webb AG, Sweedler JV. 1999. A microcoil NMR probe for coupling microscale HPLC with on-line NMR spectroscopy. Anal Chem 71:5335-5339.
22. Xiao HB, Krucker M, Putzbach K, Albert K. 2005. Capillary liquid chromatography-microcoil H-1 nuclear magnetic resonance spectroscopy and liquid chromatography-ion trap mass spectrometry for online structure elucidation of isoflavones in Radix astragali. J Chromatogr A 1067:135-143.
23. Corcoran O, Spraul M. 2003. LC-NMR-MS in drug discovery. Drug Discov Today 8:624-631.
24. Jaroszewski JW. 2005. Hyphenated NMR methods in natural products research, Part 2: HPLC-SPE-NMR and other new trends in NMR hyphenation. Planta Med 71:795-802.
25. Lambert M, Wolfender JL, Staerk D, Christensen B, Hostettmann K, Jaroszewski JW. 2007. Identification of natural products using HPLC-SPE combined with CapNMR. Anal Chem 79:727-735.
26. Jayawickrama DA, Sweedler JV. 2004. Dual microcoil NMR probe coupled to cyclic CE for continuous separation and analyte isolation. Anal Chem 76:4894-4900.
27. Wolters AM, Jayawickrama DA, Webb AG, Sweedler JW. 2002. NMR detection with multiple solenoidal microcoils for continuous-flow capillary electrophoresis. Anal Chem 74:5550-5555.
28. Almeida VK, Larive CK. 2005. Insights into cyclodextrin interactions during sample stacking using capillary isotachophoresis with on-line microcoil NMR detection. Magn Reson Chem 43:755-761.
29. Carr A, Almeida V, Larive CK. 2003. Method of development of capillary isotachophoresis coupled to on-line microcoil NMR. Abstr Pap Am Chem Soc 225:U130-U130.
30. Jayawickrama DA, Sweedler JV. 2004. Chiral separation of nanomole amounts of alprenolol with cITP/NMR. Anal Bioanal Chem 378:1528-1535.
31. Korir AK, Almeida VK, Malkin DS, Larive CK. 2005. Separation and analysis of nanomole quantities of heparin oligosaccharides using on-line capillary isotachophoresis coupled with NMR detection. Anal Chem 77:5998-6003.
32. Wolters AM, Jayawickrama DA, Larive CK, Sweedler JV. 2002. Insights into the cITP process using on-line NMR spectroscopy. Anal Chem 74:4191-4197.
33. Wolters AM, Jayawickrama DA, Larive CK, Sweedler JV. 2002. Capillary isotachophoresis/NMR: extension to trace impurity analysis and improved instrumental coupling. Anal Chem 74:2306-2313.
34. Wolters AM, Jayawickrama DA, Sweedler JV. 2005. Comparative analysis of a neurotoxin from Calliostoma canaliculatum by on-line capillary isotachophoresis/H-1 NMR and diffusion H-1 NMR. J Nat Prod 68:162-167.
35. 1H nuclear magnetic resonance spectroscopy. Anal Chem 79:2708-2713.
36. Cross VR, Hester RK, Waugh JS. 1976. Single coil probe with transmission-line tuning for nuclear magnetic double-resonance. Rev Sci Instrum 47:1486-1488.
37. Li Y, Webb AG, Saha S, Brey WW, Zachariah C, Edison AS. 2006. Comparison of the performance of round and rectangular wire in small solenoids for high-field NMR. Magn Reson Chem 44:255-262.
38. Gronquist M, Meinwald J, Eisner T, Schroeder FC. 2005. Exploring uncharted terrain in nature's structure space using capillary NMR Spectroscopy: 13 steroids from 50 fireflies. J Am Chem Soc 127:10810-10811.
39. Mispelter J, Lupu M, Briguet A. 2006. NMR Probeheads for Biophysical and Biomedical Applications. London: Imperial College Press.