Pd-catalyzed regioselective hydroarylation of α-(2-aminoaryl)-α,β-ynones with organoboron derivatives as a tool for the synthesis of quinolines: experimental evidence and quantum-chemical calculations

Tetrahedron

Volumn 64, Issue 22, 2008, Pages 5354-5361

  Arcadi, Antonio ^a   Aschi, Massimiliano ^a   Marinelli, Fabio ^a   Verdecchia, Mirella ^a  

^a UNIVERSITY OF L'AQUILA   (Italy)

Author keywords

Alkynones; Boronic acids; DFT calculations; Hydroarylation; Palladium; Quinolines

Indexed keywords

1 [3 [2 (4 CHLOROPHENYL)QUINOLIN 4 YL]PHENYL]ETHANONE; 1 [3 [6,8 DIFLUORO 2(2 METHOXYPHENYL)QUINOLIN 4 YL]PHENYL]ETHANONE; 1 [4 [4 (1 NAPHTHYL)QUINOLIN 2 YL]PHENYL]ETHANONE; 2 (4 CHLOROPHENYL) 4 (4 FLUOROPHENYL)QUINOLINE; 2 (4 METHOXYPHENYL) 4 (1 NAPHTHYL)QUINOLINE; 2 (4 METHOXYPHENYL) 4 (4 METHYLPHENYL)QUINOLINE; 2 (4 TERT BUTYL CYCLOHEX 1 ENYL) 4 (4 METHYLSULFANYLPHENYL)QUINOLINE; 2 (4 TERT BUTYL CYCLOHEX 1 ENYL) 4 PHENYL QUINOLINE; 3 (2 AMINO 3,5 DIFLUOROPHENYL) 1 (2 METHOXYPHENYL)PROP 2 YN 1 ONE; 3 (2 AMINOPHENYL) 1 (2,4 DIMETHYLPHENYL)PROP 2 YN 1 ONE; 3 (2 AMINOPHENYL) 1 (4 TERT BUTYLCYCLOHEX 1 EN 1 YL)PROP 2 YN 1 ONE; 4 [3 [2 AMINO 4 (TRIFLUOROMETHYL)PHENYL]PROP 2 YNOYL]BENZONITRILE; 4 [4 (3 METHOXYPHENYL) 7 (TRIFLUOROMETHYL)QUINOLIN 2 YL]BENZONITRILE; 4 [4 (4 METHYLPHENYL) 7 (TRIFLUOROMETHYL)QUINOLIN 2 YL]BENZONITRILE; 4 [4 (METHYLTHIO)PHENYL] 2 (1 NAPHTHYL)QUINOLINE; KETONE DERIVATIVE; ORGANOBORON DERIVATIVE; PALLADIUM; QUINOLINE DERIVATIVE;

AMINATION; ARTICLE; ARYLATION; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CHEMICAL REACTION; CRYSTAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; ISOMERISM; PRIORITY JOURNAL;

EID: 42749085676     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.03.015     Document Type: Article

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