Altered interaction between plasminogen activator inhibitor type 1 activity and sympathetic nerve activity with aging

Circulation Journal

Volumn 72, Issue 3, 2008, Pages 458-462

  Otowa, Kanichi ^a   Takamura, Masayuki ^a   Murai, Hisayoshi ^a   Maruyama, Michirou ^a   Nakano, Manabu ^a   Ikeda, Tatsunori ^a   Kobayashi, Daisuke ^a   Ootsuji, Hiroshi ^a   Okajima, Masaki ^a   Furushou, Hiroshi ^a   Yuasa, Toyoshi ^a   Takata, Shigeo ^b   Kaneko, Shuichi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b Kanazawa Municipal Hospital   (Japan)

Author keywords

Fibrinolysis; Lower body negative pressure; Muscle sympathetic nerve activity; Plasminogen activator inhibitor type 1

Indexed keywords

PLASMINOGEN ACTIVATOR INHIBITOR 1; TISSUE PLASMINOGEN ACTIVATOR;

ADULT; AGE DISTRIBUTION; AGED; AGING; ARTICLE; FEMALE; HUMAN; LOWER BODY NEGATIVE PRESSURE; MALE; NORMAL HUMAN; SYMPATHETIC TONE;

ADULT; AGED; AGING; BLOOD PRESSURE; FEMALE; FIBRINOLYSIS; HEART RATE; HUMANS; LOWER BODY NEGATIVE PRESSURE; MALE; MIDDLE AGED; MUSCLE, SKELETAL; PLASMINOGEN ACTIVATOR INHIBITOR 1; SYMPATHETIC NERVOUS SYSTEM; TISSUE PLASMINOGEN ACTIVATOR;

EID: 42649102342     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.72.458     Document Type: Article

References (42)

1. Tracy RP, Bovill EG. Thrombosis and cardiovascular risk in the elderly. Arch Pathol Lab Med 1992; 116: 1307-1312.
2. Franchira M. Hemostasia and aging. Crit Rev Oncol Hematol 2006; 60: 144-151.
3. Yamamoto K, Takeshita K, Kojima T, Takamatsu J, Saito H. Aging and plasminogen activator inhibitor-1 (PAI-1) regulation: Implication in the pathogenesis of thrombotic disorders in the elderly. Cardiovasc Res 2005; 66: 276-285.
4. Kruithof EK. Plasminogen activator inhibitors: A review. Enzyme 1988; 40: 113-121.
5. Prowse CV, Cash JD. Physiologic and pharmacologic enhancement of fibrinolysis. Semin Thromb Hemost 1984; 10: 51-60.
6. Schaefer U, Machida T, Vorlova S, Strickland S, Levi R. The plasminogen activator system modulates sympathetic nerve function. J Exp Med 2006; 203: 2191-2200.
7. Jiang X, Wang Y, Hand AR, Gillies C, Cone RE, Kirk J, et al. Storage and release of tissue plasminogen activator by sympathetic axons in resistance vessel walls. Microvasc Res 2002; 64: 438-447.
8. Wang Y, Jiang X, Hand AR, Gilles C, Kirk J, Cone RE, et al. Additional evidence mat the sympathetic nervous system regulates the vessel wall release of tissue plasminogen activator. Blood Coagul Fibrinolysis 2002; 13: 471-481.
9. Sverrisdottir YB, Johannsson G, Jungersten L, Wallin BG, Elam M. Is the somatotropic axis related to sympathetic nerve activity in healthy ageing men? J Hypertens 2001; 19: 2019-2024.
10. Ebert TJ, Morgan BJ, Barney JA, Denahan T, Smith JJ. Effects of aging on baroreflex regulation of sympathetic activity in humans. Am J Physiol 1992; 263: H798-H803.
11. Ng AV, Callister R, Johnson DG, Seals DR. Age and gender influence muscle sympathetic nerve activity at rest in healthy humans. Hypertension 1993; 21: 498-503.
12. Jones PP, Davy KP, Alexander S, Seals DR. Age-related increase in muscle sympathetic nerve activity is associated with abdominal adiposity. Am J Physiol 1997; 272: E976-E980.
13. Lecomte D, Fornes P, Nicolas G. Stressful events as a trigger of sudden death: A study of 43 medico-legal autopsy cases. Forensic Sci Int 1996; 79: 1-10.
14. Jern C, Eriksson E, Tengborn L, Risberg B, Wadenvik H, Jern S. Changes of plasma coagulation and fibrinolysis in response to mental stress. Thromb Haemost 1989; 62: 767-771.
15. Camejo G, Hurt E, Wiklund O, Rosengren B, Lopez F, Bondjers G. Modifications of low-density lipoprotein induced by arterial proteoglycans and chondroitin-6-sulfate. Biochim Biophys Acta 1991; 1096: 253-261.
16. Goldstein DS. Plasma catecholamines and essential hypertension: An analytical review. Hypertension 1983; 5: 86-99.
17. Peles E, Goldstein DS, Akselrod S, Nitzan H, Azaria M, Almog S, et al. Interrelationships among measures of autonomic activity and cardiovascular risk factors during orthostasis and the oral glucose tolerance test. Clin Auton Res 1995; 5: 271-278.
18. Abe M, Iwaoka M, Nakamura T, Kitta Y, Takano H, Kodama Y, et al. Association of high levels of plasma free dopamine with future coronary events in patients with coronary artery disease. Circ J 2007; 71: 688-692.
19. Nakamura M, Lee DP, Yeung AC. Identification and treatment of vulnerable plaque. Rev Cardiovasc Med 2004; 5(Suppl 2): S22-S33.
20. Shah PK. Plaque disruption and coronary thrombosis: New insight into pathogenesis and prevention. Clin Cardiol 1997; 20(Suppl): II-33-II-44.
21. Yuasa T, Takata S, Mamyama M, Yasuma K, Yoshizawa H, Kontani M, et al. Low-dose atropine attenuates muscle sympathetic nerve activity in healthy humans. Hypertens Res 2000; 23: 213-218.
22. Murai H, Takata S, Mamyama M, Nakano M, Kobayashi D, Otowa K, et al. The activity of a single muscle sympathetic vasoconstrictor nerve unit is affected by physiological stress in humans. Am J Physiol Heart Circ Physiol 2006; 290: H853-H860.
23. Miskin R, Abramovitz R. Enhancement of PAI-1 mRNA in cardiovascular cells after kainate injection is mediated through the sympathetic nervous system. J Mol Cell Cardiol 2005; 38: 715-722.
24. Larsson PT, Wiman B, Olsson G, Angelin B, Hjemdahl P. Influence of metoprolol treatment on sympathoadrenal activation of fibrinolysis. Thromb Haemost 1990; 63: 482-487.
25. Yamamoto K, Takeshita K Shimokawa T, Yi H, Isobe K, Loskutoff DJ, et al. Plasminogen activator inhibitor-1 is a major stress-regulated gene: Implications for stress-induced thrombosis in aged individuals. Proc Natl Acad Sci USA 2002; 99: 890-895.
26. Konkle BA, Schuster SJ, Kelly MD, Harjes K, Hassett DE, Bohrer M, et al. Plasminogen activator inhibitor-1 messenger RNA expression is induced in rat hepatocytes in vivo by dexamethasone. Blood 1992; 79: 2636-2642.
27. Yamamoto K, Saito H. A pathological role of increased expression of plasminogen activator inhibitor-1 in human or animal disorders. Int J Hematol 1998; 68: 371-385.
28. Hamsten A, Wiman B, de Faire U, Blomback M. Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction. N Engl J Med 1985; 313: 1557-1563.
29. Wiman B, Hamsten A. The fibrinolytic enzyme system and its role in the etiology of thromboembolic disease. Semin Thromb Hemost 1990; 16: 207-216.
30. Pralong G, Calandra T, Glauser MP, Schellekens J, Verhoef J, Bachmann F, et al. Plasminogen activator inhibitor 1: A new prognostic marker in septic shock. Thromb Haemost 1989; 61: 459-462.
31. Naya M, Tsukamoto T, Inubushi M, Morita K Katoh C, Fummoto T, et al. Elevated plasma plasminogen activator inhibitor type-1 is an independent predictor of coronary microvascular dysfunction in hypertension. Circ J 2007; 71: 348-353.
32. Malyszko J, Urano T, Takada Y, Takada A. Stress-dependent changes in fibrinolysis, serotonin and platelet aggregation in rats. Life Sci 1994; 54: 1275-1280.
33. Takada Y, Urano T, Takahashi H, Nagai N, Takada A. Effects of electric footshock and water immersion restraint stresses on fibrinolytic parameters in the plasma of rats. Thromb Res 1998; 89: 107-114.
34. van der Poll T, Levi M, Dentener M, Jansen PM, Coyle SM, Braxton CC, et al. Epinephrine exerts anticoagulant effects during human endotoxemia. J Exp Med 1997; 185: 1143-1148.
35. Wallen NH, Larsson PT, Broijersen A, Andersson A, Hjemdahl P. Effects of an oral dose of isosorbide dinitrate on platelet function and fibrinolysis in healthy volunteers. Br J Clin Pharmacol 1993; 35: 143-151.
36. Chandler WL, Levy WC, Veith RC, Stratton JR. A kinetic model of the circulatory regulation of tissue plasminogen activator during exercise, epinephrine infusion, and endurance training. Blood 1993; 81: 3293-3302.
37. von Kanel R, Dimsdale JE. Effects of sympathetic activation by adrenergic infusions on hemostasis in vivo. Eur J Haematol 2000; 65: 357-369.
38. Yamazaki H, Sano T, Odakura T, Takeuchi K, Matsumura T, Hosaki S, et al. Appearance of thrombogenic tendency induced by adrenaline and its prevention by adrenergic blocking agent, nialamide and pyridinolcarbamate. Thromb Diath Haemorrh 1971; 26: 251-263.
39. Chandler WL, Levy WC, Stratton JR. The circulatory regulation of TPA and UPA secretion, clearance, and inhibition during exercise and during the infusion of isoproterenol and phenylephrine. Circulation 1995; 92: 2984-2994.
40. Kido M, Hitosugi M, Yokoyama T, Tokudome S. Sudden death while bathing. Nippon Rinsho 2005; 63: 1239-1242 (in Japanese).
41. Baily RG, Sinoway LI. Insight into human baroreceptor function using multiple indices of neural activity. Heart Fail 1990; 6: 33-41.
42. Sander-Jensen K, Mehlsen J, Stadeager C, Christensen NJ, Fahrenkrug J, Schwartz TW, et al. Increase in vagal activity during hypotensive lower-body negative pressure in humans. Am J Physiol 1988; 255: R149-R156.