-
1
-
-
1242306914
-
Increased fasting total homocysteine plasma levels as a risk factor for thromboembolism in children
-
Childhood Thrombophilia Study Group
-
Kosch A.K., Koch H.G., Heinecke A., Kurnik K., Heller C., Nowak-Gottl U., and Childhood Thrombophilia Study Group. Increased fasting total homocysteine plasma levels as a risk factor for thromboembolism in children. Thromb Haemost 91 2 (2004) 308-314
-
(2004)
Thromb Haemost
, vol.91
, Issue.2
, pp. 308-314
-
-
Kosch, A.K.1
Koch, H.G.2
Heinecke, A.3
Kurnik, K.4
Heller, C.5
Nowak-Gottl, U.6
-
2
-
-
0031971515
-
A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?
-
van der Put N.M., Gabreels F., Stevens E.M., Smeitink J.A., Trijbels F.J., Eskes T.K., et al. A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?. Am J Hum Genet 62 5 (1998) 1044-1051
-
(1998)
Am J Hum Genet
, vol.62
, Issue.5
, pp. 1044-1051
-
-
van der Put, N.M.1
Gabreels, F.2
Stevens, E.M.3
Smeitink, J.A.4
Trijbels, F.J.5
Eskes, T.K.6
-
3
-
-
0037321186
-
Hyperhomocysteinemia and thrombosis
-
Lee R., and Frenkel E.P. Hyperhomocysteinemia and thrombosis. Hematol Oncol Clin North Am 17 1 (2003) 85-102
-
(2003)
Hematol Oncol Clin North Am
, vol.17
, Issue.1
, pp. 85-102
-
-
Lee, R.1
Frenkel, E.P.2
-
4
-
-
0032569645
-
Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease
-
Ray J.G. Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease. Arch Intern Med 158 19 (1998) 2101-2106
-
(1998)
Arch Intern Med
, vol.158
, Issue.19
, pp. 2101-2106
-
-
Ray, J.G.1
-
5
-
-
0042919553
-
Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China
-
Li Z., Sun L., Zhang H., Liao Y., Wang D., Zhao B., et al. Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China. Stroke 34 9 (2003) 2085-2090
-
(2003)
Stroke
, vol.34
, Issue.9
, pp. 2085-2090
-
-
Li, Z.1
Sun, L.2
Zhang, H.3
Liao, Y.4
Wang, D.5
Zhao, B.6
-
6
-
-
0033609098
-
Hyperhomocysteinemia: a risk factor for ischemic stroke in children
-
van Beynum I.M., Smeitink J.A., den Heijer M., te Poele Pothoff M.T., and Blom H.J. Hyperhomocysteinemia: a risk factor for ischemic stroke in children. Circulation 99 16 (1999) 2070-2072
-
(1999)
Circulation
, vol.99
, Issue.16
, pp. 2070-2072
-
-
van Beynum, I.M.1
Smeitink, J.A.2
den Heijer, M.3
te Poele Pothoff, M.T.4
Blom, H.J.5
-
7
-
-
0033737294
-
A meta-analysis of cerebrovascular disease and hyperhomocysteinaemia
-
Moller J., Nielsen G.M., Tvedegaard K.C., Andersen N.T., and Jorgensen P.E. A meta-analysis of cerebrovascular disease and hyperhomocysteinaemia. Scand J Clin Lab Invest 60 6 (2000) 491-499
-
(2000)
Scand J Clin Lab Invest
, vol.60
, Issue.6
, pp. 491-499
-
-
Moller, J.1
Nielsen, G.M.2
Tvedegaard, K.C.3
Andersen, N.T.4
Jorgensen, P.E.5
-
8
-
-
33845718808
-
Homocysteine, MTHFR C677 T, vitamin B12, and folate levels in Thai children with ischemic stroke: a case-control study
-
Sirachainan N., Tapanapruksakul P., Visudtibhan A., Chuansumrit A., Cheeramakara C., Atamasirikul K., et al. Homocysteine, MTHFR C677 T, vitamin B12, and folate levels in Thai children with ischemic stroke: a case-control study. J Pediatr Hematol/Oncol 28 12 (2006) 803-808
-
(2006)
J Pediatr Hematol/Oncol
, vol.28
, Issue.12
, pp. 803-808
-
-
Sirachainan, N.1
Tapanapruksakul, P.2
Visudtibhan, A.3
Chuansumrit, A.4
Cheeramakara, C.5
Atamasirikul, K.6
-
9
-
-
0036324658
-
Hyperhomocyst(e) inemia and risk of ischemic stroke among young Asian adults
-
Tan N.C., Venketasubramanian N., Saw S.M., and Tjia H.T. Hyperhomocyst(e) inemia and risk of ischemic stroke among young Asian adults. Stroke 33 8 (2002) 1956-1962
-
(2002)
Stroke
, vol.33
, Issue.8
, pp. 1956-1962
-
-
Tan, N.C.1
Venketasubramanian, N.2
Saw, S.M.3
Tjia, H.T.4
-
10
-
-
28344446460
-
Mechanisms of homocysteine-induced atherothrombosis
-
Lentz S.R. Mechanisms of homocysteine-induced atherothrombosis. J Thromb Haemost 3 8 (2005) 1646-1654
-
(2005)
J Thromb Haemost
, vol.3
, Issue.8
, pp. 1646-1654
-
-
Lentz, S.R.1
-
11
-
-
0029049553
-
A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase
-
Frosst P., Blom H.J., Milos R., Goyette P., Sheppard C.A., Matthews R.G., et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 10 1 (1995) 111-113
-
(1995)
Nat Genet
, vol.10
, Issue.1
, pp. 111-113
-
-
Frosst, P.1
Blom, H.J.2
Milos, R.3
Goyette, P.4
Sheppard, C.A.5
Matthews, R.G.6
-
12
-
-
0029655724
-
Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease
-
Kluijtmans L.A., van den Heuvel L.P., Boers G.H., Frosst P., Stevens E.M., van Oost B.A., et al. Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet 58 1 (1996) 35-41
-
(1996)
Am J Hum Genet
, vol.58
, Issue.1
, pp. 35-41
-
-
Kluijtmans, L.A.1
van den Heuvel, L.P.2
Boers, G.H.3
Frosst, P.4
Stevens, E.M.5
van Oost, B.A.6
-
13
-
-
0030826587
-
Thermolabile methylenetetrahydrofolate reductase in coronary artery disease
-
Kluijtmans L.A., Kastelein J.J., Lindemans J., Boers G.H., Heil S.G., Bruschke A.V., et al. Thermolabile methylenetetrahydrofolate reductase in coronary artery disease. Circulation 96 8 (1997) 2573-2577
-
(1997)
Circulation
, vol.96
, Issue.8
, pp. 2573-2577
-
-
Kluijtmans, L.A.1
Kastelein, J.J.2
Lindemans, J.3
Boers, G.H.4
Heil, S.G.5
Bruschke, A.V.6
-
14
-
-
0030897112
-
Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease
-
Morita H., Taguchi J., Kurihara H., Kitaoka M., Kaneda H., Kurihara Y., et al. Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease. Circulation 95 8 (1997) 2032-2036
-
(1997)
Circulation
, vol.95
, Issue.8
, pp. 2032-2036
-
-
Morita, H.1
Taguchi, J.2
Kurihara, H.3
Kitaoka, M.4
Kaneda, H.5
Kurihara, Y.6
-
15
-
-
0032497941
-
Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis
-
Brattstrom L., Wilcken D.E., Ohrvik J., and Brudin L. Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis. Circulation 98 23 (1998) 2520-2526
-
(1998)
Circulation
, vol.98
, Issue.23
, pp. 2520-2526
-
-
Brattstrom, L.1
Wilcken, D.E.2
Ohrvik, J.3
Brudin, L.4
-
16
-
-
0030476385
-
Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine metabolism and late-onset vascular disease
-
Deloughery T.G., Evans A., Sadeghi A., McWilliams J., Henner W.D., Taylor Jr. L.M., et al. Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine metabolism and late-onset vascular disease. Circulation 94 12 (1996) 3074-3078
-
(1996)
Circulation
, vol.94
, Issue.12
, pp. 3074-3078
-
-
Deloughery, T.G.1
Evans, A.2
Sadeghi, A.3
McWilliams, J.4
Henner, W.D.5
Taylor Jr., L.M.6
-
17
-
-
0031025577
-
Methylenetetrahydrofolate reductase gene and coronary artery disease
-
van Bockxmeer F.M., Mamotte C.D., Vasikaran S.D., and Taylor R.R. Methylenetetrahydrofolate reductase gene and coronary artery disease. Circulation 95 1 (1997) 21-23
-
(1997)
Circulation
, vol.95
, Issue.1
, pp. 21-23
-
-
van Bockxmeer, F.M.1
Mamotte, C.D.2
Vasikaran, S.D.3
Taylor, R.R.4
-
18
-
-
0035500262
-
Gene polymorphisms of homocysteine metabolism-related enzymes in Chinese patients with occlusive coronary artery or cerebral vascular diseases
-
Zhang G., and Dai C. Gene polymorphisms of homocysteine metabolism-related enzymes in Chinese patients with occlusive coronary artery or cerebral vascular diseases. Thromb Res 104 3 (2001) 187-195
-
(2001)
Thromb Res
, vol.104
, Issue.3
, pp. 187-195
-
-
Zhang, G.1
Dai, C.2
-
19
-
-
0017671144
-
Identification of a nondeletion defect in alpha-thalassemia
-
Kan Y.W., Dozy A.M., Trecartin R., and Todd D. Identification of a nondeletion defect in alpha-thalassemia. N Engl J Med 297 20 (1977) 1081-1084
-
(1977)
N Engl J Med
, vol.297
, Issue.20
, pp. 1081-1084
-
-
Kan, Y.W.1
Dozy, A.M.2
Trecartin, R.3
Todd, D.4
-
20
-
-
10544249877
-
Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders
-
Leclerc D., Campeau E., Goyette P., Adjalla C.E., Christensen B., Ross M., et al. Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders. Hum Mol Genet 5 12 (1996) 1867-1874
-
(1996)
Hum Mol Genet
, vol.5
, Issue.12
, pp. 1867-1874
-
-
Leclerc, D.1
Campeau, E.2
Goyette, P.3
Adjalla, C.E.4
Christensen, B.5
Ross, M.6
-
21
-
-
30444457210
-
Relationship of homocysteine and gene polymorphisms of its related metabolic enzymes with Alzheimer's disease
-
Zhang Y.D., Ke X.Y., Shen W., and Liu Y. Relationship of homocysteine and gene polymorphisms of its related metabolic enzymes with Alzheimer's disease. Chin Med Sci J 20 4 (2005) 247-251
-
(2005)
Chin Med Sci J
, vol.20
, Issue.4
, pp. 247-251
-
-
Zhang, Y.D.1
Ke, X.Y.2
Shen, W.3
Liu, Y.4
-
22
-
-
0035870971
-
Common mutations at the homocysteine metabolism pathway and pediatric stroke
-
Akar N., Akar E., Ozel D., Deda G., and Sipahi T. Common mutations at the homocysteine metabolism pathway and pediatric stroke. Thromb Res 102 2 (2001) 115-120
-
(2001)
Thromb Res
, vol.102
, Issue.2
, pp. 115-120
-
-
Akar, N.1
Akar, E.2
Ozel, D.3
Deda, G.4
Sipahi, T.5
-
23
-
-
0345633546
-
Lipoprotein (a) and genetic polymorphisms of clotting factor V, prothrombin, and methylenetetrahydrofolate reductase are risk factors of spontaneous ischemic stroke in childhood
-
Nowak-Gottl U., Strater R., Heinecke A., Junker R., Koch H.G., Schuierer G., et al. Lipoprotein (a) and genetic polymorphisms of clotting factor V, prothrombin, and methylenetetrahydrofolate reductase are risk factors of spontaneous ischemic stroke in childhood. Blood 94 11 (1999) 3678-3682
-
(1999)
Blood
, vol.94
, Issue.11
, pp. 3678-3682
-
-
Nowak-Gottl, U.1
Strater, R.2
Heinecke, A.3
Junker, R.4
Koch, H.G.5
Schuierer, G.6
-
24
-
-
0033861598
-
Prevalence of methylenetetrahydrofolate reductase C677T and its association with arterial and venous thrombosis in the Chinese population
-
Zheng Y.Z., Tong J., Do X.P., Pu X.Q., and Zhou B.T. Prevalence of methylenetetrahydrofolate reductase C677T and its association with arterial and venous thrombosis in the Chinese population. Br J Haematol 109 4 (2000) 870-874
-
(2000)
Br J Haematol
, vol.109
, Issue.4
, pp. 870-874
-
-
Zheng, Y.Z.1
Tong, J.2
Do, X.P.3
Pu, X.Q.4
Zhou, B.T.5
-
25
-
-
18344364639
-
Plasma homocysteine concentration, C677T MTHFR genotype, and 844ins68bp CBS genotype in young adults with spontaneous cervical artery dissection and atherothrombotic stroke
-
Pezzini A., Del Zotto E., Archetti S., Negrini R., Bani P., Albertini A., et al. Plasma homocysteine concentration, C677T MTHFR genotype, and 844ins68bp CBS genotype in young adults with spontaneous cervical artery dissection and atherothrombotic stroke. Stroke 33 3 (2002) 664-669
-
(2002)
Stroke
, vol.33
, Issue.3
, pp. 664-669
-
-
Pezzini, A.1
Del Zotto, E.2
Archetti, S.3
Negrini, R.4
Bani, P.5
Albertini, A.6
-
26
-
-
0032966833
-
Polymorphism of the methionine synthase gene association with homocysteine metabolism and late-onset vascular diseases in the Japanese population
-
Morita H., Kurihara H., Sugiyama T., Hamada C., Kurihara Y., Shindo T., et al. Polymorphism of the methionine synthase gene association with homocysteine metabolism and late-onset vascular diseases in the Japanese population. Arterioscler Thromb Vasc Biol 19 2 (1999) 298-302
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, Issue.2
, pp. 298-302
-
-
Morita, H.1
Kurihara, H.2
Sugiyama, T.3
Hamada, C.4
Kurihara, Y.5
Shindo, T.6
-
27
-
-
0034128553
-
Factor V Leiden and antiphospholipid antibodies are significant risk factors for ischemic stroke in children
-
Kenet G., Sadetzki S., Murad H., Martinowitz U., Rosenberg N., Gitel S., et al. Factor V Leiden and antiphospholipid antibodies are significant risk factors for ischemic stroke in children. Stroke 31 6 (2000) 1283-1288
-
(2000)
Stroke
, vol.31
, Issue.6
, pp. 1283-1288
-
-
Kenet, G.1
Sadetzki, S.2
Murad, H.3
Martinowitz, U.4
Rosenberg, N.5
Gitel, S.6
-
28
-
-
0035057410
-
C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase gene: incidence and effect of combined genotypes on plasma fasting and post-methionine load homocysteine in vascular disease
-
Hanson N.Q., Aras O., Yang F., and Tsai M.Y. C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase gene: incidence and effect of combined genotypes on plasma fasting and post-methionine load homocysteine in vascular disease. Clin Chem 47 4 (2001) 661-666
-
(2001)
Clin Chem
, vol.47
, Issue.4
, pp. 661-666
-
-
Hanson, N.Q.1
Aras, O.2
Yang, F.3
Tsai, M.Y.4
-
29
-
-
0034190659
-
5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review
-
Botto L.D., and Yang Q. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. Am J Epidemiol 151 9 (2000) 862-877
-
(2000)
Am J Epidemiol
, vol.151
, Issue.9
, pp. 862-877
-
-
Botto, L.D.1
Yang, Q.2
-
30
-
-
1442300286
-
Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review
-
Sharp L., and Little J. Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review. Am J Epidemiol 159 5 (2004) 423-443
-
(2004)
Am J Epidemiol
, vol.159
, Issue.5
, pp. 423-443
-
-
Sharp, L.1
Little, J.2
-
31
-
-
0037377977
-
5,10-Methylenetetrahydrofolate reductase polymorphisms and leukemia risk: a HuGE minireview
-
Robien K., and Ulrich C.M. 5,10-Methylenetetrahydrofolate reductase polymorphisms and leukemia risk: a HuGE minireview. Am J Epidemiol 157 7 (2003) 571-582
-
(2003)
Am J Epidemiol
, vol.157
, Issue.7
, pp. 571-582
-
-
Robien, K.1
Ulrich, C.M.2
|