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Volumn 122, Issue 1, 2008, Pages 33-37

The effect of polymorphisms of MTHFR C677T, A1298C, MS A2756G and CBS 844ins68bp on plasma total homocysteine level and the risk of ischemic stroke in Thai children

Author keywords

A1298C; CBS 844ins68bp; Children; Homocysteine; Ischemic stroke; MS A2756G; MTHFR C677T

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); HOMOCYSTEINE;

EID: 42649095999     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2007.09.012     Document Type: Article
Times cited : (16)

References (31)
  • 1
    • 1242306914 scopus 로고    scopus 로고
    • Increased fasting total homocysteine plasma levels as a risk factor for thromboembolism in children
    • Childhood Thrombophilia Study Group
    • Kosch A.K., Koch H.G., Heinecke A., Kurnik K., Heller C., Nowak-Gottl U., and Childhood Thrombophilia Study Group. Increased fasting total homocysteine plasma levels as a risk factor for thromboembolism in children. Thromb Haemost 91 2 (2004) 308-314
    • (2004) Thromb Haemost , vol.91 , Issue.2 , pp. 308-314
    • Kosch, A.K.1    Koch, H.G.2    Heinecke, A.3    Kurnik, K.4    Heller, C.5    Nowak-Gottl, U.6
  • 2
    • 0031971515 scopus 로고    scopus 로고
    • A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?
    • van der Put N.M., Gabreels F., Stevens E.M., Smeitink J.A., Trijbels F.J., Eskes T.K., et al. A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?. Am J Hum Genet 62 5 (1998) 1044-1051
    • (1998) Am J Hum Genet , vol.62 , Issue.5 , pp. 1044-1051
    • van der Put, N.M.1    Gabreels, F.2    Stevens, E.M.3    Smeitink, J.A.4    Trijbels, F.J.5    Eskes, T.K.6
  • 3
    • 0037321186 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and thrombosis
    • Lee R., and Frenkel E.P. Hyperhomocysteinemia and thrombosis. Hematol Oncol Clin North Am 17 1 (2003) 85-102
    • (2003) Hematol Oncol Clin North Am , vol.17 , Issue.1 , pp. 85-102
    • Lee, R.1    Frenkel, E.P.2
  • 4
    • 0032569645 scopus 로고    scopus 로고
    • Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease
    • Ray J.G. Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease. Arch Intern Med 158 19 (1998) 2101-2106
    • (1998) Arch Intern Med , vol.158 , Issue.19 , pp. 2101-2106
    • Ray, J.G.1
  • 5
    • 0042919553 scopus 로고    scopus 로고
    • Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China
    • Li Z., Sun L., Zhang H., Liao Y., Wang D., Zhao B., et al. Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China. Stroke 34 9 (2003) 2085-2090
    • (2003) Stroke , vol.34 , Issue.9 , pp. 2085-2090
    • Li, Z.1    Sun, L.2    Zhang, H.3    Liao, Y.4    Wang, D.5    Zhao, B.6
  • 9
    • 0036324658 scopus 로고    scopus 로고
    • Hyperhomocyst(e) inemia and risk of ischemic stroke among young Asian adults
    • Tan N.C., Venketasubramanian N., Saw S.M., and Tjia H.T. Hyperhomocyst(e) inemia and risk of ischemic stroke among young Asian adults. Stroke 33 8 (2002) 1956-1962
    • (2002) Stroke , vol.33 , Issue.8 , pp. 1956-1962
    • Tan, N.C.1    Venketasubramanian, N.2    Saw, S.M.3    Tjia, H.T.4
  • 10
    • 28344446460 scopus 로고    scopus 로고
    • Mechanisms of homocysteine-induced atherothrombosis
    • Lentz S.R. Mechanisms of homocysteine-induced atherothrombosis. J Thromb Haemost 3 8 (2005) 1646-1654
    • (2005) J Thromb Haemost , vol.3 , Issue.8 , pp. 1646-1654
    • Lentz, S.R.1
  • 11
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase
    • Frosst P., Blom H.J., Milos R., Goyette P., Sheppard C.A., Matthews R.G., et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 10 1 (1995) 111-113
    • (1995) Nat Genet , vol.10 , Issue.1 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3    Goyette, P.4    Sheppard, C.A.5    Matthews, R.G.6
  • 12
    • 0029655724 scopus 로고    scopus 로고
    • Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease
    • Kluijtmans L.A., van den Heuvel L.P., Boers G.H., Frosst P., Stevens E.M., van Oost B.A., et al. Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet 58 1 (1996) 35-41
    • (1996) Am J Hum Genet , vol.58 , Issue.1 , pp. 35-41
    • Kluijtmans, L.A.1    van den Heuvel, L.P.2    Boers, G.H.3    Frosst, P.4    Stevens, E.M.5    van Oost, B.A.6
  • 14
    • 0030897112 scopus 로고    scopus 로고
    • Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease
    • Morita H., Taguchi J., Kurihara H., Kitaoka M., Kaneda H., Kurihara Y., et al. Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease. Circulation 95 8 (1997) 2032-2036
    • (1997) Circulation , vol.95 , Issue.8 , pp. 2032-2036
    • Morita, H.1    Taguchi, J.2    Kurihara, H.3    Kitaoka, M.4    Kaneda, H.5    Kurihara, Y.6
  • 15
    • 0032497941 scopus 로고    scopus 로고
    • Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis
    • Brattstrom L., Wilcken D.E., Ohrvik J., and Brudin L. Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis. Circulation 98 23 (1998) 2520-2526
    • (1998) Circulation , vol.98 , Issue.23 , pp. 2520-2526
    • Brattstrom, L.1    Wilcken, D.E.2    Ohrvik, J.3    Brudin, L.4
  • 16
    • 0030476385 scopus 로고    scopus 로고
    • Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine metabolism and late-onset vascular disease
    • Deloughery T.G., Evans A., Sadeghi A., McWilliams J., Henner W.D., Taylor Jr. L.M., et al. Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine metabolism and late-onset vascular disease. Circulation 94 12 (1996) 3074-3078
    • (1996) Circulation , vol.94 , Issue.12 , pp. 3074-3078
    • Deloughery, T.G.1    Evans, A.2    Sadeghi, A.3    McWilliams, J.4    Henner, W.D.5    Taylor Jr., L.M.6
  • 17
    • 0031025577 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase gene and coronary artery disease
    • van Bockxmeer F.M., Mamotte C.D., Vasikaran S.D., and Taylor R.R. Methylenetetrahydrofolate reductase gene and coronary artery disease. Circulation 95 1 (1997) 21-23
    • (1997) Circulation , vol.95 , Issue.1 , pp. 21-23
    • van Bockxmeer, F.M.1    Mamotte, C.D.2    Vasikaran, S.D.3    Taylor, R.R.4
  • 18
    • 0035500262 scopus 로고    scopus 로고
    • Gene polymorphisms of homocysteine metabolism-related enzymes in Chinese patients with occlusive coronary artery or cerebral vascular diseases
    • Zhang G., and Dai C. Gene polymorphisms of homocysteine metabolism-related enzymes in Chinese patients with occlusive coronary artery or cerebral vascular diseases. Thromb Res 104 3 (2001) 187-195
    • (2001) Thromb Res , vol.104 , Issue.3 , pp. 187-195
    • Zhang, G.1    Dai, C.2
  • 19
    • 0017671144 scopus 로고
    • Identification of a nondeletion defect in alpha-thalassemia
    • Kan Y.W., Dozy A.M., Trecartin R., and Todd D. Identification of a nondeletion defect in alpha-thalassemia. N Engl J Med 297 20 (1977) 1081-1084
    • (1977) N Engl J Med , vol.297 , Issue.20 , pp. 1081-1084
    • Kan, Y.W.1    Dozy, A.M.2    Trecartin, R.3    Todd, D.4
  • 20
    • 10544249877 scopus 로고    scopus 로고
    • Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders
    • Leclerc D., Campeau E., Goyette P., Adjalla C.E., Christensen B., Ross M., et al. Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders. Hum Mol Genet 5 12 (1996) 1867-1874
    • (1996) Hum Mol Genet , vol.5 , Issue.12 , pp. 1867-1874
    • Leclerc, D.1    Campeau, E.2    Goyette, P.3    Adjalla, C.E.4    Christensen, B.5    Ross, M.6
  • 21
    • 30444457210 scopus 로고    scopus 로고
    • Relationship of homocysteine and gene polymorphisms of its related metabolic enzymes with Alzheimer's disease
    • Zhang Y.D., Ke X.Y., Shen W., and Liu Y. Relationship of homocysteine and gene polymorphisms of its related metabolic enzymes with Alzheimer's disease. Chin Med Sci J 20 4 (2005) 247-251
    • (2005) Chin Med Sci J , vol.20 , Issue.4 , pp. 247-251
    • Zhang, Y.D.1    Ke, X.Y.2    Shen, W.3    Liu, Y.4
  • 22
    • 0035870971 scopus 로고    scopus 로고
    • Common mutations at the homocysteine metabolism pathway and pediatric stroke
    • Akar N., Akar E., Ozel D., Deda G., and Sipahi T. Common mutations at the homocysteine metabolism pathway and pediatric stroke. Thromb Res 102 2 (2001) 115-120
    • (2001) Thromb Res , vol.102 , Issue.2 , pp. 115-120
    • Akar, N.1    Akar, E.2    Ozel, D.3    Deda, G.4    Sipahi, T.5
  • 23
    • 0345633546 scopus 로고    scopus 로고
    • Lipoprotein (a) and genetic polymorphisms of clotting factor V, prothrombin, and methylenetetrahydrofolate reductase are risk factors of spontaneous ischemic stroke in childhood
    • Nowak-Gottl U., Strater R., Heinecke A., Junker R., Koch H.G., Schuierer G., et al. Lipoprotein (a) and genetic polymorphisms of clotting factor V, prothrombin, and methylenetetrahydrofolate reductase are risk factors of spontaneous ischemic stroke in childhood. Blood 94 11 (1999) 3678-3682
    • (1999) Blood , vol.94 , Issue.11 , pp. 3678-3682
    • Nowak-Gottl, U.1    Strater, R.2    Heinecke, A.3    Junker, R.4    Koch, H.G.5    Schuierer, G.6
  • 24
    • 0033861598 scopus 로고    scopus 로고
    • Prevalence of methylenetetrahydrofolate reductase C677T and its association with arterial and venous thrombosis in the Chinese population
    • Zheng Y.Z., Tong J., Do X.P., Pu X.Q., and Zhou B.T. Prevalence of methylenetetrahydrofolate reductase C677T and its association with arterial and venous thrombosis in the Chinese population. Br J Haematol 109 4 (2000) 870-874
    • (2000) Br J Haematol , vol.109 , Issue.4 , pp. 870-874
    • Zheng, Y.Z.1    Tong, J.2    Do, X.P.3    Pu, X.Q.4    Zhou, B.T.5
  • 25
    • 18344364639 scopus 로고    scopus 로고
    • Plasma homocysteine concentration, C677T MTHFR genotype, and 844ins68bp CBS genotype in young adults with spontaneous cervical artery dissection and atherothrombotic stroke
    • Pezzini A., Del Zotto E., Archetti S., Negrini R., Bani P., Albertini A., et al. Plasma homocysteine concentration, C677T MTHFR genotype, and 844ins68bp CBS genotype in young adults with spontaneous cervical artery dissection and atherothrombotic stroke. Stroke 33 3 (2002) 664-669
    • (2002) Stroke , vol.33 , Issue.3 , pp. 664-669
    • Pezzini, A.1    Del Zotto, E.2    Archetti, S.3    Negrini, R.4    Bani, P.5    Albertini, A.6
  • 26
    • 0032966833 scopus 로고    scopus 로고
    • Polymorphism of the methionine synthase gene association with homocysteine metabolism and late-onset vascular diseases in the Japanese population
    • Morita H., Kurihara H., Sugiyama T., Hamada C., Kurihara Y., Shindo T., et al. Polymorphism of the methionine synthase gene association with homocysteine metabolism and late-onset vascular diseases in the Japanese population. Arterioscler Thromb Vasc Biol 19 2 (1999) 298-302
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , Issue.2 , pp. 298-302
    • Morita, H.1    Kurihara, H.2    Sugiyama, T.3    Hamada, C.4    Kurihara, Y.5    Shindo, T.6
  • 27
    • 0034128553 scopus 로고    scopus 로고
    • Factor V Leiden and antiphospholipid antibodies are significant risk factors for ischemic stroke in children
    • Kenet G., Sadetzki S., Murad H., Martinowitz U., Rosenberg N., Gitel S., et al. Factor V Leiden and antiphospholipid antibodies are significant risk factors for ischemic stroke in children. Stroke 31 6 (2000) 1283-1288
    • (2000) Stroke , vol.31 , Issue.6 , pp. 1283-1288
    • Kenet, G.1    Sadetzki, S.2    Murad, H.3    Martinowitz, U.4    Rosenberg, N.5    Gitel, S.6
  • 28
    • 0035057410 scopus 로고    scopus 로고
    • C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase gene: incidence and effect of combined genotypes on plasma fasting and post-methionine load homocysteine in vascular disease
    • Hanson N.Q., Aras O., Yang F., and Tsai M.Y. C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase gene: incidence and effect of combined genotypes on plasma fasting and post-methionine load homocysteine in vascular disease. Clin Chem 47 4 (2001) 661-666
    • (2001) Clin Chem , vol.47 , Issue.4 , pp. 661-666
    • Hanson, N.Q.1    Aras, O.2    Yang, F.3    Tsai, M.Y.4
  • 29
    • 0034190659 scopus 로고    scopus 로고
    • 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review
    • Botto L.D., and Yang Q. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. Am J Epidemiol 151 9 (2000) 862-877
    • (2000) Am J Epidemiol , vol.151 , Issue.9 , pp. 862-877
    • Botto, L.D.1    Yang, Q.2
  • 30
    • 1442300286 scopus 로고    scopus 로고
    • Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review
    • Sharp L., and Little J. Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review. Am J Epidemiol 159 5 (2004) 423-443
    • (2004) Am J Epidemiol , vol.159 , Issue.5 , pp. 423-443
    • Sharp, L.1    Little, J.2
  • 31
    • 0037377977 scopus 로고    scopus 로고
    • 5,10-Methylenetetrahydrofolate reductase polymorphisms and leukemia risk: a HuGE minireview
    • Robien K., and Ulrich C.M. 5,10-Methylenetetrahydrofolate reductase polymorphisms and leukemia risk: a HuGE minireview. Am J Epidemiol 157 7 (2003) 571-582
    • (2003) Am J Epidemiol , vol.157 , Issue.7 , pp. 571-582
    • Robien, K.1    Ulrich, C.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.