메뉴 건너뛰기




Volumn 68, Issue 4, 2008, Pages 997-1017

A novel autotransporter of uropathogenic Proteus mirabilis is both a cytotoxin and an agglutinin

Author keywords

[No Author keywords available]

Indexed keywords

AGGLUTININ; CHYMOSTATIN; CHYMOTRYPSIN; CYTOTOXIN; LEUPEPTIN; OUTER MEMBRANE PROTEIN; PROTEUS TOXIC AGGLUTININ; UNCLASSIFIED DRUG; UREASE;

EID: 42549168663     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2008.06199.x     Document Type: Article
Times cited : (65)

References (45)
  • 1
    • 33645865541 scopus 로고    scopus 로고
    • Type IV secretion systems and their effectors in bacterial pathogenesis
    • Backert, S. Meyer, T.F. (2006) Type IV secretion systems and their effectors in bacterial pathogenesis. Curr Opin Microbiol 9 : 207 217.
    • (2006) Curr Opin Microbiol , vol.9 , pp. 207-217
    • Backert, S.1    Meyer, T.F.2
  • 2
    • 33845232496 scopus 로고    scopus 로고
    • Adjuvant and immunogenic activities of the 73 kDa N-terminal alpha-domain of BrkA autotransporter and Cpn60/60 kDa chaperonin of Bordetella pertussis
    • Cainelli Gebara, V.C., Risoleo, L., Lopes, A.P., Ferreira, V.R., Quintilio, W., Lepine, F., et al. (2007) Adjuvant and immunogenic activities of the 73 kDa N-terminal alpha-domain of BrkA autotransporter and Cpn60/60 kDa chaperonin of Bordetella pertussis. Vaccine 25 : 621 629.
    • (2007) Vaccine , vol.25 , pp. 621-629
    • Cainelli Gebara, V.C.1    Risoleo, L.2    Lopes, A.P.3    Ferreira, V.R.4    Quintilio, W.5    Lepine, F.6
  • 3
    • 0028132873 scopus 로고
    • Internalization of Proteus mirabilis by human renal epithelial cells
    • Chippendale, G.R., Warren, J.W., Trifillis, A.L. Mobley, H.L. (1994) Internalization of Proteus mirabilis by human renal epithelial cells. Infect Immun 62 : 3115 3121.
    • (1994) Infect Immun , vol.62 , pp. 3115-3121
    • Chippendale, G.R.1    Warren, J.W.2    Trifillis, A.L.3    Mobley, H.L.4
  • 4
    • 27844506497 scopus 로고    scopus 로고
    • Type II secretion: A protein secretion system for all seasons
    • Cianciotto, N.P. (2005) Type II secretion: a protein secretion system for all seasons. Trends Microbiol 13 : 581 588.
    • (2005) Trends Microbiol , vol.13 , pp. 581-588
    • Cianciotto, N.P.1
  • 5
    • 0033763785 scopus 로고    scopus 로고
    • Pathogenesis of Proteus mirabilis urinary tract infection
    • Coker, C., Poore, C.A., Li, X. Mobley, H.L. (2000) Pathogenesis of Proteus mirabilis urinary tract infection. Microbes Infect 2 : 1497 1505.
    • (2000) Microbes Infect , vol.2 , pp. 1497-1505
    • Coker, C.1    Poore, C.A.2    Li, X.3    Mobley, H.L.4
  • 6
    • 18044363515 scopus 로고    scopus 로고
    • Trimeric autotransporters: A distinct subfamily of autotransporter proteins
    • 3rd (
    • Cotter, S.E., Surana, N.K. St Geme, J.W., 3rd (2005) Trimeric autotransporters: a distinct subfamily of autotransporter proteins. Trends Microbiol 13 : 199 205.
    • (2005) Trends Microbiol , vol.13 , pp. 199-205
    • Cotter, S.E.1    Surana, N.K.2    St Geme, J.W.3
  • 7
    • 33746659490 scopus 로고    scopus 로고
    • Trimeric autotransporters require trimerization of the passenger domain for stability and adhesive activity
    • 3rd (
    • Cotter, S.E., Surana, N.K., Grass, S. St Geme, J.W., 3rd (2006) Trimeric autotransporters require trimerization of the passenger domain for stability and adhesive activity. J Bacteriol 188 : 5400 5407.
    • (2006) J Bacteriol , vol.188 , pp. 5400-5407
    • Cotter, S.E.1    Surana, N.K.2    Grass, S.3    St Geme, J.W.4
  • 8
    • 33744519083 scopus 로고    scopus 로고
    • Adhesion mediated by autotransporters of Gram-negative bacteria: Structural and functional features
    • Girard, V. Mourez, M. (2006) Adhesion mediated by autotransporters of Gram-negative bacteria: structural and functional features. Res Microbiol 157 : 407 416.
    • (2006) Res Microbiol , vol.157 , pp. 407-416
    • Girard, V.1    Mourez, M.2
  • 9
    • 0036070744 scopus 로고    scopus 로고
    • Sat, the secreted autotransporter toxin of uropathogenic Escherichia coli, is a vacuolating cytotoxin for bladder and kidney epithelial cells
    • Guyer, D.M., Radulovic, S., Jones, F.E. Mobley, H.L. (2002) Sat, the secreted autotransporter toxin of uropathogenic Escherichia coli, is a vacuolating cytotoxin for bladder and kidney epithelial cells. Infect Immun 70 : 4539 4546.
    • (2002) Infect Immun , vol.70 , pp. 4539-4546
    • Guyer, D.M.1    Radulovic, S.2    Jones, F.E.3    Mobley, H.L.4
  • 11
    • 0035111746 scopus 로고    scopus 로고
    • Virulence functions of autotransporter proteins
    • Henderson, I.R. Nataro, J.P. (2001) Virulence functions of autotransporter proteins. Infect Immun 69 : 1231 1243.
    • (2001) Infect Immun , vol.69 , pp. 1231-1243
    • Henderson, I.R.1    Nataro, J.P.2
  • 12
    • 0032169654 scopus 로고    scopus 로고
    • The great escape: Structure and function of the autotransporter proteins
    • Henderson, I.R., Navarro-Garcia, F. Nataro, J.P. (1998) The great escape: structure and function of the autotransporter proteins. Trends Microbiol 6 : 370 378.
    • (1998) Trends Microbiol , vol.6 , pp. 370-378
    • Henderson, I.R.1    Navarro-Garcia, F.2    Nataro, J.P.3
  • 13
    • 0032734808 scopus 로고    scopus 로고
    • Characterization of pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli
    • Henderson, I.R., Czeczulin, J., Eslava, C., Noriega, F. Nataro, J.P. (1999) Characterization of pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli. Infect Immun 67 : 5587 5596.
    • (1999) Infect Immun , vol.67 , pp. 5587-5596
    • Henderson, I.R.1    Czeczulin, J.2    Eslava, C.3    Noriega, F.4    Nataro, J.P.5
  • 15
    • 0025646802 scopus 로고
    • Subtilisin-like proteinases involved in the activation of proproteins of the eukaryotic secretory pathway
    • Hutton, J.C. (1990) Subtilisin-like proteinases involved in the activation of proproteins of the eukaryotic secretory pathway. Curr Opin Cell Biol 2 : 1131 1142.
    • (1990) Curr Opin Cell Biol , vol.2 , pp. 1131-1142
    • Hutton, J.C.1
  • 16
    • 0027200202 scopus 로고
    • Contribution of Proteus mirabilis urease to persistence, urolithiasis, and acute pyelonephritis in a mouse model of ascending urinary tract infection
    • Johnson, D.E., Russell, R.G., Lockatell, C.V., Zulty, J.C., Warren, J.W. Mobley, H.L. (1993) Contribution of Proteus mirabilis urease to persistence, urolithiasis, and acute pyelonephritis in a mouse model of ascending urinary tract infection. Infect Immun 61 : 2748 2754.
    • (1993) Infect Immun , vol.61 , pp. 2748-2754
    • Johnson, D.E.1    Russell, R.G.2    Lockatell, C.V.3    Zulty, J.C.4    Warren, J.W.5    Mobley, H.L.6
  • 17
    • 33846191083 scopus 로고    scopus 로고
    • Identification and characterization of an RTX toxin in the emerging pathogen Kingella kingae
    • 3rd (
    • Kehl-Fie, T.E. St Geme, J.W., 3rd (2007) Identification and characterization of an RTX toxin in the emerging pathogen Kingella kingae. J Bacteriol 189 : 430 436.
    • (2007) J Bacteriol , vol.189 , pp. 430-436
    • Kehl-Fie, T.E.1    St Geme, J.W.2
  • 18
    • 33745875356 scopus 로고    scopus 로고
    • Self-associating autotransporters, SAATs: Functional and structural similarities
    • Klemm, P., Vejborg, R.M. Sherlock, O. (2006) Self-associating autotransporters, SAATs: functional and structural similarities. Int J Med Microbiol 296 : 187 195.
    • (2006) Int J Med Microbiol , vol.296 , pp. 187-195
    • Klemm, P.1    Vejborg, R.M.2    Sherlock, O.3
  • 19
    • 0036595837 scopus 로고    scopus 로고
    • Molecular characterization of fervidolysin, a subtilisin-like serine protease from the thermophilic bacterium Fervidobacterium pennivorans
    • Kluskens, L.D., Voorhorst, W.G., Siezen, R.J., Schwerdtfeger, R.M., Antranikian, G., van der Oost, J. de Vos, W.M. (2002) Molecular characterization of fervidolysin, a subtilisin-like serine protease from the thermophilic bacterium Fervidobacterium pennivorans. Extremophiles 6 : 185 194.
    • (2002) Extremophiles , vol.6 , pp. 185-194
    • Kluskens, L.D.1    Voorhorst, W.G.2    Siezen, R.J.3    Schwerdtfeger, R.M.4    Antranikian, G.5    Van Der Oost, J.6    De Vos, W.M.7
  • 20
    • 0036021482 scopus 로고    scopus 로고
    • Vaccines for Proteus mirabilis in urinary tract infection
    • Li, X. Mobley, H.L. (2002) Vaccines for Proteus mirabilis in urinary tract infection. Int J Antimicrob Agents 19 : 461 465.
    • (2002) Int J Antimicrob Agents , vol.19 , pp. 461-465
    • Li, X.1    Mobley, H.L.2
  • 21
    • 0033023392 scopus 로고    scopus 로고
    • Requirement of MrpH for mannose-resistant Proteus-like fimbria-mediated hemagglutination by Proteus mirabilis
    • Li, X., Johnson, D.E. Mobley, H.L. (1999) Requirement of MrpH for mannose-resistant Proteus-like fimbria-mediated hemagglutination by Proteus mirabilis. Infect Immun 67 : 2822 2833.
    • (1999) Infect Immun , vol.67 , pp. 2822-2833
    • Li, X.1    Johnson, D.E.2    Mobley, H.L.3
  • 22
    • 9244255314 scopus 로고    scopus 로고
    • The C-terminal fragment of the internal 110-kilodalton passenger domain of the Hap protein of nontypeable Haemophilus influenzae is a potential vaccine candidate
    • Liu, D.F., Mason, K.W., Mastri, M., Pazirandeh, M., Cutter, D., Fink, D.L., et al. (2004) The C-terminal fragment of the internal 110-kilodalton passenger domain of the Hap protein of nontypeable Haemophilus influenzae is a potential vaccine candidate. Infect Immun 72 : 6961 6968.
    • (2004) Infect Immun , vol.72 , pp. 6961-6968
    • Liu, D.F.1    Mason, K.W.2    Mastri, M.3    Pazirandeh, M.4    Cutter, D.5    Fink, D.L.6
  • 24
    • 0001925226 scopus 로고    scopus 로고
    • Virulence of Proteus mirabilis
    • In. Mobley, H.L. Warren, J.W. (eds). Washington, DC: American Society for Microbiology Press, pp.
    • Mobley, H.L. (1996b) Virulence of Proteus mirabilis. In Urinary Tract Infections: Molecular Pathogenesis and Clinical Management. Mobley, H.L. Warren, J.W. (eds). Washington, DC : American Society for Microbiology Press, pp. 245 269.
    • (1996) Urinary Tract Infections: Molecular Pathogenesis and Clinical Management. , pp. 245-269
    • Mobley, H.L.1
  • 25
    • 0023636563 scopus 로고
    • Urease-positive bacteriuria and obstruction of long-term urinary catheters
    • Mobley, H.L. Warren, J.W. (1987) Urease-positive bacteriuria and obstruction of long-term urinary catheters. J Clin Microbiol 25 : 2216 2217.
    • (1987) J Clin Microbiol , vol.25 , pp. 2216-2217
    • Mobley, H.L.1    Warren, J.W.2
  • 26
    • 0025758569 scopus 로고
    • Cytotoxicity of the HpmA hemolysin and urease of Proteus mirabilis and Proteus vulgaris against cultured human renal proximal tubular epithelial cells
    • Mobley, H.L., Chippendale, G.R., Swihart, K.G. Welch, R.A. (1991) Cytotoxicity of the HpmA hemolysin and urease of Proteus mirabilis and Proteus vulgaris against cultured human renal proximal tubular epithelial cells. Infect Immun 59 : 2036 2042.
    • (1991) Infect Immun , vol.59 , pp. 2036-2042
    • Mobley, H.L.1    Chippendale, G.R.2    Swihart, K.G.3    Welch, R.A.4
  • 27
    • 21344453525 scopus 로고    scopus 로고
    • The bacterial injection kit: Type III secretion systems
    • Mota, L.J. Cornelis, G.R. (2005) The bacterial injection kit: type III secretion systems. Ann Med 37 : 234 249.
    • (2005) Ann Med , vol.37 , pp. 234-249
    • Mota, L.J.1    Cornelis, G.R.2
  • 28
    • 0032948817 scopus 로고    scopus 로고
    • Cytoskeletal effects induced by pet, the serine protease enterotoxin of enteroaggregative Escherichia coli
    • Navarro-Garcia, F., Sears, C., Eslava, C., Cravioto, A. Nataro, J.P. (1999) Cytoskeletal effects induced by pet, the serine protease enterotoxin of enteroaggregative Escherichia coli. Infect Immun 67 : 2184 2192.
    • (1999) Infect Immun , vol.67 , pp. 2184-2192
    • Navarro-Garcia, F.1    Sears, C.2    Eslava, C.3    Cravioto, A.4    Nataro, J.P.5
  • 29
    • 2542576380 scopus 로고    scopus 로고
    • The serine protease motif of EspC from enteropathogenic Escherichia coli produces epithelial damage by a mechanism different from that of Pet toxin from enteroaggregative E. coli
    • Navarro-Garcia, F., Canizalez-Roman, A., Sui, B.Q., Nataro, J.P. Azamar, Y. (2004) The serine protease motif of EspC from enteropathogenic Escherichia coli produces epithelial damage by a mechanism different from that of Pet toxin from enteroaggregative E. coli. Infect Immun 72 : 3609 3621.
    • (2004) Infect Immun , vol.72 , pp. 3609-3621
    • Navarro-Garcia, F.1    Canizalez-Roman, A.2    Sui, B.Q.3    Nataro, J.P.4    Azamar, Y.5
  • 30
    • 34248393808 scopus 로고    scopus 로고
    • Pet, a non-AB toxin, is transported and translocated into epithelial cells by a retrograde trafficking pathway
    • Navarro-Garcia, F., Canizalez-Roman, A., Burlingame, K.E., Teter, K. Vidal, J.E. (2007) Pet, a non-AB toxin, is transported and translocated into epithelial cells by a retrograde trafficking pathway. Infect Immun 75 : 2101 2109.
    • (2007) Infect Immun , vol.75 , pp. 2101-2109
    • Navarro-Garcia, F.1    Canizalez-Roman, A.2    Burlingame, K.E.3    Teter, K.4    Vidal, J.E.5
  • 31
    • 3142696899 scopus 로고    scopus 로고
    • A new family of potent AB(5) cytotoxins produced by Shiga toxigenic Escherichia coli
    • Paton, A.W., Srimanote, P., Talbot, U.M., Wang, H. Paton, J.C. (2004) A new family of potent AB(5) cytotoxins produced by Shiga toxigenic Escherichia coli. J Exp Med 200 : 35 46.
    • (2004) J Exp Med , vol.200 , pp. 35-46
    • Paton, A.W.1    Srimanote, P.2    Talbot, U.M.3    Wang, H.4    Paton, J.C.5
  • 32
    • 33749522548 scopus 로고    scopus 로고
    • AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP
    • Paton, A.W., Beddoe, T., Thorpe, C.M., Whisstock, J.C., Wilce, M.C., Rossjohn, J., et al. (2006) AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP. Nature 443 : 548 552.
    • (2006) Nature , vol.443 , pp. 548-552
    • Paton, A.W.1    Beddoe, T.2    Thorpe, C.M.3    Whisstock, J.C.4    Wilce, M.C.5    Rossjohn, J.6
  • 33
    • 36148932613 scopus 로고    scopus 로고
    • The type III secretion system of Proteus mirabilis HI4320 does not contribute to virulence in the mouse model of ascending urinary tract infection
    • Pearson, M.M. Mobley, H.L. (2007) The type III secretion system of Proteus mirabilis HI4320 does not contribute to virulence in the mouse model of ascending urinary tract infection. J Med Microbiol 56 : 1277 1283.
    • (2007) J Med Microbiol , vol.56 , pp. 1277-1283
    • Pearson, M.M.1    Mobley, H.L.2
  • 34
    • 42549140786 scopus 로고    scopus 로고
    • The complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility
    • in press).
    • Pearson, M.M., Sebaihia, M., Churcher, C., Quail, M.A., Seshasayee, A.S., Abdellah, Z., et al. (2008) The complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility. J Bacteriol (in press).
    • (2008) J Bacteriol
    • Pearson, M.M.1    Sebaihia, M.2    Churcher, C.3    Quail, M.A.4    Seshasayee, A.S.5    Abdellah, Z.6
  • 36
    • 0035145673 scopus 로고    scopus 로고
    • Vacuolating cytotoxin of Helicobacter pylori plays a role during colonization in a mouse model of infection
    • Salama, N.R., Otto, G., Tompkins, L. Falkow, S. (2001) Vacuolating cytotoxin of Helicobacter pylori plays a role during colonization in a mouse model of infection. Infect Immun 69 : 730 736.
    • (2001) Infect Immun , vol.69 , pp. 730-736
    • Salama, N.R.1    Otto, G.2    Tompkins, L.3    Falkow, S.4
  • 37
    • 0029521155 scopus 로고    scopus 로고
    • Subtilases: Subtilisin-like serine proteases
    • Seizen, R.J. (1996) Subtilases: subtilisin-like serine proteases. Adv Exp Med Biol 379 : 75 93.
    • (1996) Adv Exp Med Biol , vol.379 , pp. 75-93
    • Seizen, R.J.1
  • 38
    • 0033842544 scopus 로고    scopus 로고
    • Secretion of virulence determinants by the general secretory pathway in gram-negative pathogens: An evolving story
    • 3rd, and. 3rd (
    • Stathopoulos, C., Hendrixson, D.R., Thanassi, D.G., Hultgren, S.J., St Geme, J.W., 3rd, and Curtiss, R., 3rd (2000) Secretion of virulence determinants by the general secretory pathway in gram-negative pathogens: an evolving story. Microbes Infect 2 : 1061 1072.
    • (2000) Microbes Infect , vol.2 , pp. 1061-1072
    • Stathopoulos, C.1    Hendrixson, D.R.2    Thanassi, D.G.3    Hultgren, S.J.4    St Geme, J.W.5    Curtiss, R.6
  • 39
    • 0031995477 scopus 로고    scopus 로고
    • The proprotein convertases
    • Steiner, D.F. (1998) The proprotein convertases. Curr Opin Chem Biol 2 : 31 39.
    • (1998) Curr Opin Chem Biol , vol.2 , pp. 31-39
    • Steiner, D.F.1
  • 40
    • 0027722231 scopus 로고
    • Proteus mirabilis biofilms and the encrustation of urethral catheters
    • Stickler, D., Ganderton, L., King, J., Nettleton, J. Winters, C. (1993) Proteus mirabilis biofilms and the encrustation of urethral catheters. Urol Res 21 : 407 411.
    • (1993) Urol Res , vol.21 , pp. 407-411
    • Stickler, D.1    Ganderton, L.2    King, J.3    Nettleton, J.4    Winters, C.5
  • 41
    • 0025374682 scopus 로고
    • Cytotoxic activity of the Proteus hemolysin HpmA
    • Swihart, K.G. Welch, R.A. (1990) Cytotoxic activity of the Proteus hemolysin HpmA. Infect Immun 58 : 1861 1869.
    • (1990) Infect Immun , vol.58 , pp. 1861-1869
    • Swihart, K.G.1    Welch, R.A.2
  • 42
    • 34248361451 scopus 로고    scopus 로고
    • MarT activates expression of the MisL autotransporter protein in Salmonela enterica serotype Typhimurium
    • Tukel, C., Akcelik, M., de Jong, M.F., Simseko, O., Tsolis, R.M. Baumler, A.J. (2007) MarT activates expression of the MisL autotransporter protein in Salmonela enterica serotype Typhimurium. J Bact 189 : 3922 3926.
    • (2007) J Bact , vol.189 , pp. 3922-3926
    • Tukel, C.1    Akcelik, M.2    De Jong, M.F.3    Simseko, O.4    Tsolis, R.M.5    Baumler, A.J.6
  • 43
    • 0020465781 scopus 로고
    • A prospective microbiologic study of bacteriuria in patients with chronic indwelling urethral catheters
    • Warren, J.W., Tenney, J.H., Hoopes, J.M., Muncie, H.L. Anthony, W.C. (1982) A prospective microbiologic study of bacteriuria in patients with chronic indwelling urethral catheters. J Infect Dis 146 : 719 723.
    • (1982) J Infect Dis , vol.146 , pp. 719-723
    • Warren, J.W.1    Tenney, J.H.2    Hoopes, J.M.3    Muncie, H.L.4    Anthony, W.C.5
  • 44
    • 0023182435 scopus 로고
    • Fever, bacteremia, and death as complications of bacteriuria, in women with long-term urethral catheters
    • Jr (
    • Warren, J.W., Damron, D., Tenney, J.H., Hoopes, J.M., Deforge B. Muncie, H.L., Jr (1987) Fever, bacteremia, and death as complications of bacteriuria, in women with long-term urethral catheters. J Infect Dis 155 : 1151 1158.
    • (1987) J Infect Dis , vol.155 , pp. 1151-1158
    • Warren, J.W.1    Damron, D.2    Tenney, J.H.3    Hoopes, J.M.4    Deforge, B.5    Muncie, H.L.6
  • 45
    • 34547857405 scopus 로고    scopus 로고
    • Autotransporter proteins: Novel targets at the bacterial cell surface
    • Wells, T., Tree, J.J., Ulett, G.L. Schembi, M.A. (2007) Autotransporter proteins: novel targets at the bacterial cell surface. FEMS Microbiol Lett 274 : 163 172.
    • (2007) FEMS Microbiol Lett , vol.274 , pp. 163-172
    • Wells, T.1    Tree, J.J.2    Ulett, G.L.3    Schembi, M.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.