Cutaneous manifestations of cystic fibrosis

Pediatric Dermatology

Volumn 25, Issue 2, 2008, Pages 150-157

  Bernstein, Megan L ^a   McCusker, Meagen M ^b   Grant Kels, Jane M ^b  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; AZLOCILLIN; BETA LACTAM ANTIBIOTIC; CEPHALOSPORIN DERIVATIVE; CHLORIDE ION; CIPROFLOXACIN; PIPERACILLIN;

ARTHRALGIA; ATOPY; BACTERIAL INFECTION; CLINICAL FEATURE; CYSTIC FIBROSIS; DERMATITIS; DIFFERENTIAL DIAGNOSIS; DISORDERS OF LIPID AND LIPOPROTEIN METABOLISM; DRUG HYPERSENSITIVITY; FEVER; GRAM NEGATIVE INFECTION; HUMAN; HYPERSENSITIVITY REACTION; MALE INFERTILITY; NUTRIENT DEFICIENCY DERMATITIS; NUTRITIONAL DEFICIENCY; PHOTOSENSITIVITY; PRIORITY JOURNAL; RASH; RESPIRATORY TRACT INFECTION; REVIEW; SYMPTOM; URTICARIA; VASCULITIS; WRINKLE;

CYSTIC FIBROSIS; DERMATITIS; DIAGNOSIS, DIFFERENTIAL; FATTY ACIDS; FEMALE; HUMANS; MALE; VASCULITIS; ZINC;

EID: 42549155288     PISSN: 07368046     EISSN: 15251470     Source Type: Journal    
DOI: 10.1111/j.1525-1470.2008.00620.x     Document Type: Review

References (75)

1. Economou-Mavrou C, Antonakakis C, Matsaniotis N. Letter: skin wrinkling in cystic fibrosis. Lancet 1974 2 : 953.
2. Elliott RB. Letter: skin wrinkling in cystic fibrosis. Lancet 1974 2 : 1383.
3. Elliott RB. Letter: wrinkling of skin in cystic fibrosis. Lancet 1974 2 : 108.
4. Johns MK. Skin wrinkling in cystic fibrosis. Med Biol Illus 1975 25 : 205 210.
5. Katz KA, Yan AC, Turner ML. Aquagenic wrinkling of the palms in patients with cystic fibrosis homozygous for the delta F508 CFTR mutation. Arch Dermatol 2005 141 : 621 624.
6. Moynahan EJ. Letter: skin wrinkling in cystic fibrosis. Lancet 1974 2 : 907.
7. Norman AP, Mall ML, Johns MK. Letter: skin wrinkling in cystic fibrosis. Lancet 1974 2 : 358 359.
8. Weinstein M, Ryan J, Rogers P. Letter: skin wrinkling and nerve function. Lancet 1974 2 : 907.
9. Schreiber R, Nitschke R, Greger R et al. The cystic fibrosis transmembrane conductance regulator activates aquaporin 3 in airway epithelial cells. J Biol Chem 1999 274 : 11811 11816.
10. Lowes MA, Khaira GS, Holt D. Transient reactive papulotranslucent acrokeratoderma associated with cystic fibrosis. Australas J Dermatol 2000 41 : 172 174.
11. Strandvik B. Relation between essential fatty acid metabolism and gastrointestinal symptoms in cystic fibrosis. Acta Paediatr Scand Suppl 1989 363 : 58 63.
12. Abman SH, Accurso FJ, Bowman CM. Persistent morbidity and mortality of protein calorie malnutrition in young infants with CF. J Pediatr Gastroenterol Nutr 1986 5 : 393 396.
13. Darmstadt GL, McGuire J, Ziboh VA. Malnutrition-associated rash of cystic fibrosis. Pediatr Dermatol 2000 17 : 337 347.
14. Darmstadt GL, Schmidt CP, Wechsler DS et al. Dermatitis as a presenting sign of cystic fibrosis. Arch Dermatol 1992 128 : 1358 1364.
15. Bhura-Bandali FN, Suh M, Man SF et al. The deltaF508 mutation in the cystic fibrosis transmembrane conductance regulator alters control of essential fatty acid utilization in epithelial cells. J Nutr 2000 130 : 2870 2875.
16. Hansen RC, Lemen R, Revsin B. Cystic fibrosis manifesting with acrodermatitis enteropathica-like eruption. Association with essential fatty acid and zinc deficiencies. Arch Dermatol 1983 119 : 51 55.
17. Patrizi A, Bianchi F, Neri I et al. Acrodermatitis enteropathica-like eruption: a sign of malabsorption in cystic fibrosis. Pediatr Dermatol 2003 20 : 187 188.
18. Phillips RJ, Crock CM, Dillon MJ et al. Cystic fibrosis presenting as kwashiorkor with florid skin rash. Arch Dis Child 1993 69 : 446 448.
19. Roulet M, Frascarolo P, Rappaz I et al. Essential fatty acid deficiency in well nourished young cystic fibrosis patients. Eur J Pediatr 1997 156 : 952 956.
20. Schmidt CP, Tunnessen W. Cystic fibrosis presenting with periorificial dermatitis. J Am Acad Dermatol 1991 25 : 896 897.
21. Fradin MS, Kalb RE, Grossman ME. Recurrent cutaneous vasculitis in cystic fibrosis. Pediatr Dermatol 1987 4 : 108 111.
22. Garty BZ, Scanlin T, Goldsmith DP et al. Cutaneous manifestations of cystic fibrosis: possible role of cryoglobulins. Br J Dermatol 1989 121 : 655 658.
23. Nielsen HE, Lundh S, Jacobsen SV et al. Hypergammaglobulinemic purpura in cystic fibrosis. Acta Paediatr Scand 1978 67 : 443 447.
24. Soter NA, Mihm MC Jr., Colten HR. Cutaneous necrotizing venulitis in patients with cystic fibrosis. J Pediatr 1979 95 : 197 201.
25. John EG, Medenis R, Rao S. Cutaneous necrotizing venulitis in patients with cystic fibrosis. J Pediatr 1980 97 : 505.
26. Finnegan MJ, Hinchcliffe J, Russell-Jones D et al. Vasculitis complicating cystic fibrosis. Q J Med 1989 72 : 609 621.
27. Schidlow DV, Goldsmith DP, Palmer J et al. Arthritis in cystic fibrosis. Arch Dis Child 1984 59 : 377 379.
28. Summers GD, Webley M. Episodic arthritis in cystic fibrosis: a case report. Br J Rheumatol 1986 25 : 393 395.
29. Zedek D, Morrell DS, Graham M et al. Acrodermatitis enteropathica-like eruption and failure to thrive as presenting signs of cystic fibrosis. J Am Acad Dermatol 2008 58 (Suppl S5 S8.
30. Crone J, Huber WD, Eichler I et al. Acrodermatitis enteropathica-like eruption as the presenting sign of cystic fibrosis - case report and review of the literature. Eur J Pediatr 2002 161 : 475 478.
31. Muniz AE, Bartle S, Foster R. Edema, anemia, hypoproteinemia, and acrodermatitis enteropathica: an uncommon initial presentation of cystic fibrosis. Pediatr Emerg Care 2004 20 : 112 114.
32. Osman K, Akesson A, Berglund M et al. Toxic and essential elements in placentas of Swedish women. Clin Biochem 2000 33 : 131 138.
33. Freedman SD, Katz MH, Parker EM et al. A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr(-/-) mice. Proc Natl Acad Sci U S A 1999 96 : 13995 14000.
34. Al M, van Houwelingen AC, Hornstra G. Long-chain polyunsaturated fatty acids, pregnancy, and pregnancy outcome. Am J Clin Nutr 2000 71 (Suppl. 285S 291S.
35. Thompson GN. Excessive fecal taurine loss predisposes to taurine deficiency in cystic fibrosis. J Pediatr Gastroenterol Nutr 1988 7 : 214 219.
36. Degim Z, Celebi N, Sayan H et al. An investigation on skin wound healing in mice with a taurine-chitosan gel formulation. Amino Acids 2002 22 : 187 198.
37. Belli DC, Levy E, Darling P et al. Taurine improves the absorption of a fat meal in patients with cystic fibrosis. Pediatrics 1987 80 : 517 523.
38. Skopnik H, Kusenbach G, Bergt U et al. Taurine supplementation in cystic fibrosis (CF): effect on vitamin E absorption kinetics. Klin Padiatr 1991 203 : 28 32.
39. Wilmott RW. The relationship between atopy and cystic fibrosis. Clin Rev Allergy 1991 9 : 29 46.
40. Abramovits W. Atopic dermatitis. J Am Acad Dermatol 2005 53 : S86 S93.
41. Laufer P, Fink JN, Bruns WT et al. Allergic bronchopulmonary aspergillosis in cystic fibrosis. J Allergy Clin Immunol 1984 73 : 44 48.
42. Allan JD, Moss AD, Wallwork JC et al. Immediate hypersensitivity in patients with cystic fibrosis. Clin Allergy 1975 5 : 255 261.
43. Silverman M, Hobbs FD, Gordon IR et al. Cystic fibrosis, atopy, and airways lability. Arch Dis Child 1978 53 : 873 877.
44. Nelson LA, Callerame ML, Schwartz RH. Aspergillosis and atopy in cystic fibrosis. Am Rev Respir Dis 1979 120 : 863 873.
45. Warner JO, Taylor BW, Norman AP et al. Association of cystic fibrosis with allergy. Arch Dis Child 1976 51 : 507 511.
46. Henry M, Bennett DM, Kiely J et al. Fungal atopy in adult cystic fibrosis. Respir Med 2000 94 : 1092 1096.
47. Hussain I, Smith J. Evidence for the transmissibility of atopy: hypothesis. Chest 2003 124 : 1968 1974.
48. Laufer P. Urticaria in cystic fibrosis. Cutis 1985 36 : 245 246.
49. Baxi S, Dinakar C. Urticaria and angioedema. Immunol Allergy Clin North Am 2005 25 : 353 367.
50. Koch C, Hjelt K, Pedersen SS et al. Retrospective clinical study of hypersensitivity reactions to aztreonam and six other beta-lactam antibiotics in cystic fibrosis patients receiving multiple treatment courses. Rev Infect Dis 1991 13 (Suppl. 7 S608 S611.
51. Wills R, Henry RL, Francis JL. Antibiotic hypersensitivity reactions in cystic fibrosis. J Paediatr Child Health 1998 34 : 325 329.
52. Ramesh S. Antibiotic hypersensitivity in patients with CF. Clin Rev Allergy Immunol 2002 23 : 123 141.
53. Stead RJ, Kennedy HG, Hodson ME et al. Adverse reactions to piperacillin in adults with cystic fibrosis. Thorax 1985 40 : 184 186.
54. Burdge DR, Nakielna EM, Rabin HR. Photosensitivity associated with ciprofloxacin use in adult patients with cystic fibrosis. Antimicrob Agents Chemother 1995 39 : 793.
55. Jaffe A, Bush A. If you can't stand the rash, get out of the kitchen: an unusual adverse reaction to ciprofloxacin. Pediatr Pulmonol 1999 28 : 449 450.
56. MacCormack MA, Wiss K, Malhotra R. Aquagenic syringeal acrokeratoderma: report of two teenage cases. J Am Acad Dermatol 2001 45 : 124 126.
57. Betlloch I, Vergara G, Albares MP et al. Aquagenic keratoderma. J Eur Acad Dermatol Venereol 2003 17 : 306 307.
58. Itin PH, Lautenschlager S. Aquagenic syringeal acrokeratoderma (transient reactive papulotranslucent acrokeratoderma). Dermatology 2002 204 : 8 11.
59. Yan AC, Aasi SZ, Alms WJ et al. Aquagenic palmoplantar keratoderma. J Am Acad Dermatol 2001 44 : 696 699.
60. English JC 3rd., McCollough ML. Transient reactive papulotranslucent acrokeratoderma. J Am Acad Dermatol 1996 34 : 686 687.
61. Hodson ME, Beldon I, Batten JC. Circulating immune complexes in patients with cystic fibrosis in relation to clinical features. Clin Allergy 1985 15 : 363 370.
62. Disis ML, McDonald TL, Colombo JL et al. Circulating immune complexes in cystic fibrosis and their correlation to clinical parameters. Pediatr Res 1986 20 : 385 390.
63. Abman SH, Ogle JW, Harbeck RJ et al. Early bacteriologic, immunologic, and clinical courses of young infants with cystic fibrosis identified by neonatal screening. J Pediatr 1991 119 : 211 217.
64. Gonzalez EB, Conn DL. Hypersensitivity vasculitis (Small-vessel cutaneous vasculitis). In Kelly's Textbook of Rheumatology, 6th ed. Philadelphia, PA : W.B. Saunders, 2001.
65. Hodson ME. Vasculitis and arthropathy in cystic fibrosis. J R Soc Med 1992 85 (Suppl. 19 38 40.
66. Manthei U, Taussig LM, Beckerman RC et al. Circulating immune complexes in cystic fibrosis. Am Rev Respir Dis 1982 126 : 253 257.
67. Ginsburg R, Robertson A Jr., Michel B. Acrodermatitis enteropathico. Abnormalities of fat metabolism and integumental ultrastructures in infants. Arch Dermatol 1976 112 : 653 660.
68. Eastlack JP, Grande KK, Levy ML et al. Dermatosis in a child with kwashiorkor secondary to food aversion. Pediatr Dermatol 1999 16 : 95 102.
69. Farber S. VG: clinical pathological conference. J Pediatr 1961 59 : 451 459.
70. Skolnik P, Eaglstein WH, Ziboh VA. Human essential fatty acid deficiency: treatment by topical application of linoleic acid. Arch Dermatol 1977 113 : 939 941.
71. Wood LG, Fitzgerald DA, Garg ML. Hypothesis: vitamin E complements polyunsaturated fatty acids in essential fatty acid deficiency in cystic fibrosis. J Am Coll Nutr 2003 22 : 253 257.
72. Healy E, Meenan FO, Fitzgerald MX et al. Basal cell carcinoma and cystic fibrosis: a report of two cases. Br J Dermatol 1993 128 : 701 702.
73. Mascaro JM Jr., Ferrando J, Bombi JA et al. Congenital generalized follicular hamartoma associated with alopecia and cystic fibrosis in three siblings. Arch Dermatol 1995 131 : 454 458.
74. Prendiville J, Thiessen P, Mallory SB. Neutrophilic dermatoses in two children with idiopathic neutropenia: association with granulocyte colony-stimulating factor (G-CSF) therapy. Pediatr Dermatol 2001 18 : 417 421.
75. Rubio-Gonzalez T, Alvarez-Valiente H. Neurofibromatosis and cystic fibrosis: a case report. Rev Neurol 1999 29 : 604 606.