A modified mini-stroke model with region-directed reperfusion in rat cortex

Journal of Cerebral Blood Flow and Metabolism

Volumn 28, Issue 5, 2008, Pages 973-983

  Luo, Weihua ^a   Wang, Zhen ^a   Li, Pengcheng ^a   Zeng, Shaoqun ^a   Luo, Qingming ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Cerebral blood flow; Cerebral ischemia; Laser speckle; Optical imaging; Somatosensory cortex; Stroke, experimental

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN INFARCTION SIZE; CAROTID ARTERY LIGATION; COMMON CAROTID ARTERY; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION; SOMATOSENSORY CORTEX; STROKE;

ANIMALS; CEREBRAL INFARCTION; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; LASERS; LIGATION; MALE; MODELS, NEUROLOGICAL; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SOMATOSENSORY CORTEX; STROKE;

EID: 42549111635     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600591     Document Type: Article

References (40)

1. Atochin DN, Murciano JC, Gursoy-Ozdemir Y, Krasik T, Noda F, Ayata C, Dunn AK, Moskowitz MA, Huang PL, Muzykantov VR (2004) Mouse model of microembolic stroke and reperfusion. Stroke 35:2177-82
2. Ayata C, Dunn AK, Gursoy-Ozdemir Y, Huang Z, Boas DA, Moskowitz MA (2004a) Laser speckle flowmetry for the study of cerebrovascular physiology in normal and ischemic mouse cortex. J Cereb Blood Flow Metab 24:744-55
3. Ayata C, Shin HK, Salomone S, Ozdemir-Gursoy Y, Boas DA, Dunn AK, Moskowitz MA (2004b) Pronounced hypoperfusion during spreading depression in mouse cortex. J Cereb Blood Flow Metab 24:1172-82
4. Belayev L, Alonso OF, Busto R, Zhao W, Ginsberg MD (1996) Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model. Stroke 27:1616-22
5. Briers JD, Webster S (1996) Laser speckle contrast analysis (LASCA): a nonscanning, full-field technique for monitoring capillary blood flow. J Biomed Opt 1:174-9
6. Brozici M, van der Zwan A, Berend Hillen MD (2003) Anatomy and functionality of leptomeningeal anastomoses: a review. Stroke 34:2750-62
7. Buchan AM, Xue D, Slivka A (1992) A new model of temporary focal neocortical ischemia in the rat. Stroke 23:273-9
8. Carmichael ST (2003) Plasticity of cortical projections after stroke. Neuroscientist 9:64-75
9. Carmichael ST (2005) Rodent models of focal stroke: size, mechanism, and purpose. NeuroRx 2:396-409
10. Cheng H, Luo Q, Zeng S, Chen S, Cen J, Gong H (2003) Modified laser speckle imaging method with improved spatial resolution. J Biomed Opt 8:559-64
11. Dirnagl U, Simon RP, Hallenbeck JM (2003) Ischemic tolerance and endogenous neuroprotection. Trends Neurosci 26:248-54
12. Dunn AK, Bolay H, Moskowitz MA, Boas DA (2001) Dynamic imaging of cerebral blood flow using laser speckle. J Cereb Blood Flow Metab 21:195-201
13. Durduran T, Burnett MG, Yu G, Zhou C, Furuya D, Yodh AG, Detre JA, Greenberg JH (2004) Spatiotemporal quantification of cerebral blood flow during functional activation in rat somatosensory cortex using laser-speckle flowmetry. J Cereb Blood Flow Metab 24:518-25
14. Heiss W-D (2000) Ischemic penumbra[colon] evidence from functional imaging in man. J Cereb Blood Flow Metab 20:1276-93
15. Heiss WD, Teasel RW (2006) Brain recovery and rehabilitation. Stroke 37:314-6
16. Iadecola C (2004) Neurovascular regulation in the normal brain and in Alzheimer's disease. Nat Rev Neurosci 5:347-60
17. Joshi CN, Jain SK, Murthy PS (2004) An optimized triphenyltetrazolium chloride method for identification of cerebral infarcts. Brain Res Protoc 13:11-7
18. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Vespa P, Villablanca JP, Liebeskind DS, Woods RP, Alger JR (2001) Diffusion-perfusion MRI characterization of post-recanalization hyperperfusion in humans. Neurology 57:2015-21
19. Li P, Luo Q, Luo W, Chen S, Cheng H, Zeng S (2003) Spatiotemporal characteristics of cerebral blood volume changes in rat somatosensory cortex evoked by sciatic nerve stimulation and obtained by optical imaging. J Biomed Opt 8:629-35
20. Li P, Ni S, Zhang L, Zeng S, Luo Q (2006) Imaging cerebral blood flow through the intact rat skull with temporal laser speckle imaging. Opt Lett 31:1824-6
21. Liebeskind DS (2003) Collateral circulation. Stroke 34:2279-84
22. Lo EH, Dalkara T, Moskowitz MA (2003) Mechanisms, challenges and opportunities in stroke. Nat Rev Neurosci 4:399-415
23. Luo W, Li P, Chen S, Zeng S, Luo Q (2007) Differentiating hemodynamic responses in rat primary somatosensory cortex during non-noxious and noxious electrical stimulation by optical imaging. Brain Res 1133:67-77
24. Marchal G, Young AR, Baron JC (1999) Early postischemic hyperperfusion: pathophysiologic insights from positron emission tomography. J Cereb Blood Flow Metab 19:467-82
25. Marmarou A, Abd-Elfattah Foda MA, Van Den Brink W, Campbell J, Demetriadou K (1994) A new model of diffusion brain injury in rats. I: pathophysiology and biomechanics. J Neurosurg 80:291-300
26. Paul JS, Luft AR, Yew E, Sheu FS (2006) Imaging the development of an ischemic core following photochemically induced cortical infarction in rats using Laser Speckle Contrast Analysis (LASCA). NeuroImage 29:38-45
27. Schaller B, Graf R (2004) Cerebral ischemia and reperfusion: the pathophysiologic concept as a basis for clinical therapy. J Cereb Blood Flow Metab 24:351-71
28. Shigeno T, Teasdale GM, McCulloch J, Graham DI (1985) Recirculation model following MCA occlusion in rats. Cerebral blood flow, cerebrovascular permeability, and brain edema. J Neurosurg 63:272-7
29. Strong AJ, Anderson PJ, Watts HR, Virley DJ, Lloyd A, Irving EA, Nagafuji T, Ninomiya M, Nakamura H, Dunn AK, Graf R (2007) Peri-infarct depolarizations lead to loss of perfusion in ischaemic gyrencephalic cerebral cortex. Brain 130:995-1008
30. Strong AJ, Bezzina EL, Anderson PJB, Boutelle MG, Hopwood SE, Dunn AK (2006) Evaluation of laser speckle flowmetry for imaging cortical perfusion in experimental stroke studies: quantitation of perfusion and detection of peri-infarct depolarisations. J Cereb Blood Flow Metab 26:645-53
31. Traystman RJ (2003) Animal models of focal and global cerebral ischemia. ILAR J 44:85-95
32. Tsuchidate R, He QP, Smith ML, Siesjo BK (1997) Regional cerebral blood flow during and after 2 hours of middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 17:1066-73
33. Wang Z, Hughes S, Dayasundara S, Menon RS (2007) Theoretical and experimental optimization of laser speckle contrast imaging for high specificity to brain microcirculation. J Cereb Blood Flow Metab 27:258-69
34. Ward NS, Cohen LG (2004) Mechanisms underlying recovery of motor function after stroke. Arch Neurol 61:1844-8
35. Watanabe S, Hoffman JR, Craik RL, Hand PJ, Croul SE, Reivich M, Greenberg JH (2001) A new model of localized ischemia in rat somatosensory cortex produced by cortical compression. Stroke 32:2615-23
36. Wei L, Rovainen CM, Woolsey TA (1995) Ministrokes in rat barrel cortex. Stroke 26:1459-62
37. Yao H, Sugimori H, Fukuda K, Takada J, Ooboshi H, Kitazono T, Ibayashi S, Iida M (2003) Photothrombotic middle cerebral artery occlusion and reperfusion laser system in spontaneously hypertensive rats. Stroke 34:2716-21
38. Zepeda A, Sengpiel F, Guagnelli MA, Vaca L, Arias C (2004) Functional reorganization of visual cortex maps after ischemic lesions is accompanied by changes in expression of cytoskeletal proteins and NMDA and GABA(A) receptor subunits. J Neurosci 24:1812-21
39. Zhang ZG, Zhang L, Ding G, Jiang Q, Zhang RL, Zhang X, Gan WB, Chopp M (2005) A model of mini-embolic stroke offers measurements of the neurovascular unit response in the living mouse. Stroke 36:2701-4
40. Zhao BQ, Wang S, Kim HY, Storrie H, Rosen BR, Mooney DJ, Wang X, Lo EH (2006) Role of matrix metalloproteinases in delayed cortical responses after stroke. Nat Med 12:441-5