Framing biosecurity: An alternative to the biotech revolution model?

Science and Public Policy

Volumn 35, Issue 1, 2008, Pages 45-54

  Vogel, Kathleen M ^a  

^a Department of Molecular Biology and Genetics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTECHNOLOGY; NATIONAL SECURITY; POLICY APPROACH; SECURITY THREAT; TERRORISM;

EID: 42549101293     PISSN: 03023427     EISSN: None     Source Type: Journal    
DOI: 10.3152/030234208X270513     Document Type: Article

References (68)

1. Ahuja, Anjana 2005 Terrorism with a DIY anthrax kit. The Times.
2. Bhattacharjee, Yudhijit 2006 Scientist - policy thyself. Science, Available at , last accessed 1 June 2007.
3. Binkowski, Brock F, Kathryn E Richmond, James Kaysen, Michael R Sussman and Peter J Belshaw 2005 Correcting errors in synthetic DNA through consensus shuffling. Nucleic Acids Research, 33(6), March, 1-8.
4. Brent, Roger 2005 In the valley of the shadow of death. Available at , last accessed 1 June 2007.
5. Carlson, Robert 2003 The pace and proliferation of biological technologies. BioSecurity and Bioterrorism: Biodefense Strategy, Practice, and Science, 1(3), September, 203-214.
6. Carr, Peter A, Jason S Park, Yoon-Jae Lee, Tiffany Yu, Shuguang Zhang and Joseph M Jacobson 2004 Proteinmediated error correction for de novo DNA synthesis. Nucleic Acids Research, 32(20), November, 1-9.
7. Cello, Jeronimo, AnikoV Paul and Eckard Wimmer 2002 Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural template. Science, 297(5583), August, 1016-1018.
8. Center for Strategic and International Studies 2005 Security Controls on Scientific Information and the Conduct of Scientific Research. Available at , last accessed 1 June 2007.
9. Chyba, Christopher F and Alex L Greninger 2004 Biotechnology and bioterrorism: an unprecedented world. Survival, 46(2), Summer, 1.
10. Edgerton, David 2006 Shock of the Old: Technology and Global History Since 1900. Oxford: Oxford University Press.
11. Editorial 2002 Synthetic bioterror. New York Times, A20.
12. Editorial 2003a Statement on the consideration of biodefence and biosecurity. Nature, 421(6925), 20 February, 771.
13. Editorial 2003b Uncensored exchange of scientific results. Proceedings of the National Academies of Science, 100(4), 18 February, 1464.
14. Endy, Drew 2007. Synthetic Biology and National Security. Available at , last accessed 1 June 2007.
15. Epstein, Gerald L 2003 Policies and Proposals: Addressing the Security Implications of Fundamental Biological and Biomedical Research. Available at , last accessed 1 June 2007.
16. Epstein, Gerald L 2005 Biodefense: Building a Medical Countermeasure Capability. Testimony before the Committee on Government Reform, US House of Representatives, 14 July. Available at , last accessed 31 October 2007.
17. ETC Group 2007 Extreme Genetic Engineering: An Introduction to Synthetic Biology. Available at , last accessed 1 June 2007.
18. Fleming, James Rodger 2006 The pathological history of weather and climate modification: three cycles of promise and hype. Historical Studies in the Physical and Biological Sciences, 37(1), September, 3-25.
19. Freeman, Chris and Francisco Louca 2001 As Time Goes By: From the Industrial Revolutions to the Information Revolutions. Oxford: Oxford University Press.
20. Garfinkel, Michele S, Drew Endy, Gerald L Epstein and Robert M Friedman 2007 Synthetic Genomics: Options for Governance, October, Available at: , last accessed 31 October 2007.
21. Hajer, Maarten A 2005a Rebuilding Ground Zero: the politics of performance. Planning Theory and practice, 6(4), December, 445.
22. Hajer, Maarten A 2005b Coalitions, Practices, and Meaning in Environmental Politics: From Acid Rain to BSE. In Discourse Theory in European Politics: Identity, Policy, and Governance, eds. D Howarth and J Torfing. Houndmills: Palgrave Macmillan.
23. Hedgcoe, Adam and Paul Martin 2003 The Drugs Don't Work: Expectations and the Shaping of Pharmacogenetics. Social Studies of Science, 33(3), June, 327-364.
24. Hoffman, Bruce 2006 Inside Terrorism. New York: Columbia University Press.
25. Hopkins, M M, A Kraff, P A Martin, P Nightingale and S Mahdi 2006 Is the biotechnology revolution a myth? In Comprehensive Medicinal Chemistry II, vol. 1, eds. D Triggle and J Taylor. Elsevier.
26. Hopkins, Michael M, Paul A Martin, Paul Nightingale, Alison Kraft and Surya Mahdi 2007 The myth of the biotech revolution: an assessment of technological, clinical, and organizational change. Research Policy, 36(4), May, 566-589.
27. Horrobin, David F 2003 Modern biomedical research: an internally self-consistent universe with little contact with medical reality? Nature Reviews Drug Discovery, 2, February, 151-154.
28. Horrobin, David F 2001 Realism in drug discovery: could Cassandra be right? Nature Biotechnology, 19(12), December, 1099-1100.
29. Joppi, Roberta, Vittorio Bertele and Silvio Garattini 2005 Disappointing biotech. British Medical Journal, 331(7521), 15 October, 895-897.
30. Kodumal, Sarah J, Kedar G Patel, Ralph Reid, Hugo G Menzella, Mark Welch and Daniel V Santi 2004 Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster. Proceedings of the National Academies of Science, 101(44), 2 November, 15573-15578.
31. Lakoff, Andrew 2007 Preparing for the next emergency. Public Culture, 19(2), Spring, 247-271.
32. Leitenberg, Milton 1999 Aum Shinrikyo's efforts to produce biological weapons: a case study in the serial propagation of misinformation. Terrorism and Political Violence, 11(4), Winter, 149-158.
33. McLeish, Caitriona 2006 Science and censorship in an age of bioweapons threat. Science as Culture, 15(3), September, 215-236.
34. Mulligan, John 2006 Commercial Gene Synthesis Technology. Available at , last accessed 1 June 2007.
35. NAS, US National Academies of Science 2004a Seeking Security: Pathogens, Open Access, and Genome Databases. Washington, DC: US National Academies Press.
36. NAS, US National Academies of Science 2004b Biotechnology Research in an Age of Terrorism. Washington, DC: US National Academies Press.
37. NAS, US National Academies of Science 2005 An International Perspective on Advancing Technologies and Strategies for Managing DuaI-Use Risks: Report of a Workshop, Washington, DC: US National Academies of Science Press.
38. NAS, US National Academies of Science 2006a Committee on Advances in Technology and the Prevention of Their Application to Next Generation Bioterrorism and Biological Warfare Threats. Available at , last accessed 1 June 2007.
39. NAS, US National Academies of Science 2006b Globalization, Biosecurity, and the Life Sciences. Washington, DC: US National Academies Press.
40. NAS, US National Academies of Science 2007 Interim Report on Methodological Improvements to the Department of Homeland Security's Biological Agent Risk Analysis. Washington, DC: US National Academies of Science Press.
41. Nightingale, Paul 2004 Technological capabilities, invisible infrastructure, and the un-social construction of predictability: the overlooked fixed costs of useful research. Research Policy, 33(9), November, 1259-1264.
42. Nightingale, Paul and Paul Martin 2004 The myth of the biotech revolution. TRENDS in Biotechnology, 22(11), November, 564-569.
43. NRC, US National Research Council 2003 Scientific Openness and National Security Workshop. Available at , last accessed 1 June 2007.
44. NSABB, US National Science Advisory Board for Biosecurity 2006 Addressing Biosecurity Concerns Related to the Synthesis of Select Agents. Available at , last accessed 15 January 2008.
45. O'Toole, Tara 2004 The Biotechnology Revolution and the Bioweapons Threat. Available at , last accessed 1 June 2007.
46. Pearson, Alan 2007 Federal Funding for Biological Weapons Prevention and Defense, Fiscal Years 2001 to 2008. Available at , last accessed 8 June 2007.
47. Pennisi, Elizabeth 2003 Venter cooks up a synthetic genome in record time. Science, [b 302 b](5649), 21 November, 1307.
48. Petro, James B, Theodore R Plasse and Jack A McNulty 2003 Biotechnology: impact on biological warfare and defense. [i Bio-Security and Bioterrorism: Biodefense Strategy, Practice, and Science i], 1 (3), September, 161-168.
49. Pisano, Gary 2006 Science Business: the Promise, the Reality, and the Future of Biotech. Boston: Harvard Business School Press.
50. Rappert, Brian 2006 Assessing the Benefits, Risks, and Threats of Biotechnology. Available at , last accessed 1 June 2007.
51. Rosenberg, Nathan 1979 Technological interdependence in the American economy. Technology and Culture, 20(1), January, 25-50.
52. Shea, Dana A 2006 Balancing Scientific Publication and National Security Concerns: Issues for Congress, CRS Report for Congress. Available at , last accessed on 1 June 2007.
53. Smith, Hamilton O, Clyde A Hutchinson III, Cynthia Pfannkoch and Craig J Venter 2003 Generating a synthetic genome by whole genome assembly: pX174 bactadophage from synthetic oligonucleotides. Proceedings of the National Academies of Science, 100(26), 23 December, 15440-15445.
54. Stemmer, Willem P C, Andreas Crameri, Kim D Ha, Thomas M Brennan and Herbert L Heyneker 1995 [i Gene i], 164(1), 16 October, 49-53.
55. US Centers for Disease Control. Select Agent Program, Available at , last accessed 1 June 2007.
56. US Central Intelligence Agency 2003 The Darker Bioweapons Future. Available at , last accessed 1 June 2007.
57. US House 2002 H.R. 514, Expressing serious concern regarding the publication of instructions on how to create a synthetic human polio virus, and for other purposes, 107th Cong., 2nd session. Available at , last accessed 1 June 2007.
58. USA PATRIOT Act. Available at . Last accessed 1 June 2007,
59. Vogel, Kathleen 2006 Bioweapons proliferation: where science studies and public policy collide. Social Studies of Science, 36(5), October, 659-690.
60. Vogel, Kathleen 2007 Biosecuritization: a constructivist approach to assessing bioterrorism threats (paper under review).
61. Warrick, Joby 2006a Custom-built pathogens raise fears of bioterror. Washington Post, A01.
62. Warrick, Joby 2006b The secretive fight against bioterror. Washington Post, A01.
63. Weiss, Rick 2002 Mail-order molecules brew a terrorism debate; virus created in lab raises questions of scrutiny for DNA supplies. Washington Post, A01.
64. Westphal, Sylvia Pagan 2003 Virus synthesized in a fortnight. New Scientist, 14 November. Available at , last accessed 22 May 2007.
65. Wheelis, Mark 2004 Will the new biology lead to new weapons? Arms Control Today, [b 34 b](6), July/August, 6-7.
66. White House. Project Bioshield, Available at , last accessed 1 June 2007.
67. Xiong, Ai-Sheng, Quan-Hong Yao, Ri-He Pent, Xian Li, Hui-Qin Fan, Zong-Ming Chen and Yi Li 2004 A simple, rapid, high-fidelity and cost-effective PCR-based two-step DNA synthesis method for long gene sequences. Nucleic Acids Research, 32(12), July, 1-10.
68. Young, Lei and Qihan Dong 2004 Two-step total gene synthesis method. Nucleic Acids Research, [b 32 b](7), April, 1-6.