Crystal structure of VC1805, a conserved hypothetical protein from a Vibrio cholerae pathogenicity island, reveals homology to human p32

Proteins: Structure, Function and Genetics

Volumn 71, Issue 3, 2008, Pages 1563-1571

  Sheikh, Md Arif ^a   Potter, Jane A ^a   Johnson, Kenneth A ^a   Sim, Robert B ^b   Boyd, E Fidelma ^c   Taylor, Garry L ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF DELAWARE   (United States)

Author keywords

C1q; Human p32; VC1805; Vibrio cholerae

Indexed keywords

BACTERIAL PROTEIN; COMPLEMENT COMPONENT C1Q; PROTEIN; PROTEIN P32; PROTEIN VC1805; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN VERSUS NONHUMAN DATA; HYPOTHESIS; NONHUMAN; PATHOGENICITY ISLAND; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE HOMOLOGY; STRUCTURAL HOMOLOGY; VC1805 GENE; VIBRIO CHOLERAE;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; COMPLEMENT C1Q; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; GENOMIC ISLANDS; HUMANS; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID; VIBRIO CHOLERAE;

VIBRIO CHOLERAE;

EID: 42449148750     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21993     Document Type: Article

References (47)

1. Reidl J, Klose KE. Vibrio cholerae and cholera: out of the water and into the host. FEMS Microbiol Rev 2002;26:125-139.
2. Kaper JB, Morris JG Jr, Levine MM. Cholera. Clin Microbiol Rev 1995;8:48-86.
3. Albert MJ, Siddique AK, Islam MS, Faruque AS, Ansaruzzaman M, Faruque SM, Sack RB. Large outbreak of clinical cholera due to Vibrio cholerae non-O1 in Bangladesh. Lancet 1993;341:704.
4. Karaolis DK, Johnson JA, Bailey CC, Boedeker EC, Kaper JB, Reeves PR. A Vibrio cholerae pathogenicity island associated with epidemic and pandemic strains. Proc Natl Acad Sci USA 1998;95:3134-3139.
5. Dziejman M, Balon E, Boyd D, Fraser CM, Heidelberg JF, Mekalanos JJ. Comparative genomic analysis of Vibrio cholerae: genes that correlate with cholera endemic and pandemic disease. Proc Natl Acad Sci USA 2002;99:1556-1561.
6. Jermyn WS, Boyd EF. Characterization of a novel Vibrio pathogenicity island (VPI-2) encoding neuraminidase (nanH) among toxigenic Vibrio cholerae isolates. Microbiology 2002;148(Part 11):3681-3693.
7. O'shea YA, Finnan S, Reen FJ, Morrissey JP, O'Gara F, Boyd EF. The Vibrio seventh pandemic island-II is a 26.9 kb genomic island present in Vibrio cholerae El Tor and O139 serogroup isolates that shows homology to a 43.4 kb genomic island in V. vulnificus. Microbiology 2004;150 (Part 12):4053-4063.
8. O'shea YA, Reen FJ, Quirke AM, Boyd EF. Evolutionary genetic analysis of the emergence of epidemic Vibrio cholerae isolates on the basis of comparative nucleotide sequence analysis and multilocus virulence gene profiles. J Clin Microbiol 2004;42:4657-4671.
9. Vimr ER, Kalivoda KA, Deszo EL, Steenbergen SM. Diversity of microbial sialic acid metabolism. Microbiol Mol Biol Rev 2004;68:132-153.
10. Galen JE, Ketley JM, Fasano A, Richardson SH, Wasserman SS, Kaper JB. Role of Vibrio cholerae neuraminidase in the function of cholera toxin. Infect Immun 1992;60:406-415.
11. Leslie AGW. Recent changes to the MOSFLM package for processing film and image plate data. Joint CCP4 and ESF-EAMCB newsletter on protein crystallography, 26. Daresbury, Warrington WA, England: SERC Laboratory; 1992.
12. CCP4. The CCP4 Suite: programs for protein crystallography. Acta Crystallogr 1994;D50:760-763.
13. Terwilliger TC, Berendzen J. Automated MAD and MIR structure solution. Acta Crystallogr D Biol Crystallogr 1999;55(Part 4):849-861.
14. Terwilliger TC. Maximum-likelihood density modification. Acta Crystallogr D Biol Crystallogr 2000;56(Part 8):965-972.
15. Terwilliger TC. Automated main-chain model building by template matching and iterative fragment extension. Acta Crystallogr D Biol Crystallogr 2003;59(Part 1):38-44.
16. Terwilliger TC. Automated side-chain model building and sequence assignment by template matching. Acta Crystallogr D Biol Crystallogr 2003;59(Part 1):45-49.
17. Jones TAZJ, Cowan SW, Kjeldgaard M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr A 1991;47(Part 2):110-119.
18. Emsley P, Cowtan K. Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr 2004;60(Part 12, Part 1):2126-2132.
19. The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr 1994;50(Part 5):760-763.
20. Salvador-Morales C, Flahaut E, Sim E, Sloan J, Green ML, Sim RB. Complement activation and protein adsorption by carbon nanotubes. Mol Immunol 2006;43:193-201.
21. Laskowski RA, Watson JD, Thornton JM. ProFunc: a server for predicting protein function from 3D structure. Nucleic Acids Res 2005;33(Web Server issue):W89-W93.
22. Krainer AR, Mayeda A, Kozak D, Binns G. Functional expression of cloned human splicing factor SF2: homology to RNA-binding proteins. U1 70K, and Drosophila splicing regulators Cell 1991;66:383-394.
23. Desai K, Loewenstein PM, Green M. Isolation of a cellular protein that binds to the human immunodeficiency virus Tat protein and can potentiate transactivation of the viral promoter. Proc Natl Acad Sci USA 1991;88:8875-8879.
24. Yu L, Loewenstein PM, Zhang Z, Green M. In vitro interaction of the human immunodeficiency virus type 1 Tat transactivator and the general transcription factor TFIIB with the cellular protein TAP. J Virol 1995;69:3017-3023.
25. Tange TO, Jensen TH, Kjems J. In vitro interaction between human immunodeficiency virus type 1 Rev protein and splicing factor ASF/SF2-associated protein, p32. J Biol Chem 1996;271:10066-10072.
26. Wang Y, Finan JE, Middeldorp JM, Hayward SD. P32/TAP, a cellular protein that interacts with EBNA-1 of Epstein-Barr virus. Virology 1997;236:18-29.
27. Bruni R, Roizman B. Open reading frame P - a herpes simplex virus gene repressed during productive infection encodes a protein that binds a splicing factor and reduces synthesis of viral proteins made from spliced mRNA. Proc Natl Acad Sci USA 1996;93:10423-10427.
28. Matthews DA, Russell WC Adenovirus core protein V interacts with p32 - a protein which is associated with both the mitochondria and the nucleus. J Gen Virol 1998;79(Part 7):1677-1685.
29. Simos G, Georgatos SD. The lamin B receptor-associated protein p34 shares sequence homology and antigenic determinants with the splicing factor 2-associated protein p32. FEBS Lett 1994;346:225-228.
30. Herwald H, Dedio J, Kellner R, Loos M, Muller-Esterl W. Isolation and characterization of the kininogen-binding protein p33 from endothelial cells. Identity with the gC1q receptor. J Biol Chem 1996;271:13040-13047.
31. Lim BL, Reid KB, Ghebrehiwet B, Peerschke EI, Leigh LA, Preissner KT. The binding protein for globular heads of complement C1q, gC1qR. Functional expression and characterization as a novel vitronectin binding factor. J Biol Chem 1996;271:26739-26744.
32. Deb TB, Datta K. Molecular cloning of human fibroblast hyaluronic acid-binding protein confirms its identity with P-32, a protein copurified with splicing factor SF2. Hyaluronic acid-binding protein as P-32 protein, co-purified with splicing factor SF2. J Biol Chem 1996;271:2206-2212.
33. Ghebrehiwet B, Lim BL, Peerschke EI, Willis AC, Reid KB. Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q. J Exp Med 1994;179:1809-1821.
34. Jiang J, Zhang Y, Krainer AR, Xu RM. Crystal structure of human p32, a doughnut-shaped acidic mitochondrial matrix protein. Proc Natl Acad Sci USA 1999;96:3572-3577.
35. Krissinel E, Henrick K. Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions. Acta Crystallogr D Biol Crystallogr 2004;60(Part 12, Part 1):2256-2268.
36. Satchell KJ. Activation and suppression of the proinflammatory immune response by Vibrio cholerae toxins. Microbes Infect 2003;5:1241-1247.
37. Silva TM, Schleupner MA, Tacket CO, Steiner TS, Kaper JB, Edelman R, Guerrant R. New evidence for an inflammatory component in diarrhea caused by selected new, live attenuated cholera vaccines and by El Tor and Q139 Vibrio cholerae. Infect Immun 1996;64:2362-2364.
38. Qadri F, Bhuiyan TR, Dutta KK, Raqib R, Alam MS, Alam NH, Svennerholm AM, Mathan MM. Acute dehydrating disease caused by Vibrio cholerae serogroups O1 and O139 induce increases in innate cells and inflammatory mediators at the mucosal surface of the gut. Gut 2004;53:62-69.
39. Loos M, Martin H, Petry F. The biosynthesis of C1q, the collagen-like and Fc-recognizing molecule of the complement system. Behring Inst Mitt 1989;84:32-41.
40. Morris KM, Colten HR, Bing DH. The first component of complement. A quantitative comparison of its biosynthesis in culture by human epithelial and mesenchymal cells. J Exp Med 1978;148:1007-1019.
41. Halstensen TS, Mollnes TE, Garred P, Fausa O, Brandtzaeg P. Surface epithelium related activation of complement differs in Crohn's disease and ulcerative colitis. Gut 1992;33:902-908.
42. Sim RB, Moestrup SK, Stuart GR, Lynch NJ, Lu J, Schwaeble WJ, Malhotra R. Interaction of C1q and the collectins with the potential receptors calreticulin (cC1qR/collectin receptor) and megalin. Immunobiology 1998;199:208-224.
43. Ogden CA, deCathelineau A, Hoffmann PR, Bratton D, Ghebrehiwet B, Fadok VA, Henson PM. C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells. J Exp Med 2001;194:781-795.
44. Ghiran I, Klickstein LB, Nicholson-Weller A. Calreticulin is at the surface of circulating neutrophils and uses CD59 as an adaptor molecule. J Biol Chem 2003;278:21024-21031.
45. Malhotra R, Haurum J, Thiel S, Jensenius JC, Sim RB. Pollen grains bind to lung alveolar type II cells (A549) via lung surfactant protein A (SP-A). Biosci Rep 1993;13:79-90.
46. Ghai R, Waters P, Roumenina LT, Gadjeva M, Kojouharova MS, Reid KB, Sim RB, Kishore U. C1q and its growing family. Immunobiology 2007;212:253-266.
47. Gaboriaud C, Juanhuix J, Gruez A, Lacroix M, Darnault C, Pignol D, Verger D, Fontecilla-Camps JC, Arlaud GJ. The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties. J Biol Chem 2003;278:46974-46982.