ClTi(OiPr)3-promoted reductive amination on the solid phase: Combinatorial synthesis of a biaryl-based sulfonamide library

Journal of Combinatorial Chemistry

Volumn 10, Issue 2, 2008, Pages 280-284

  Gutierrez, Corey D ^a   Bavetsias, Vassilios ^a   McDonald, Edward ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; SULFONAMIDE; TITANIUM;

ARTICLE; CHEMISTRY; COMBINATORIAL CHEMISTRY;

AMINES; COMBINATORIAL CHEMISTRY TECHNIQUES; SULFONAMIDES; TITANIUM;

EID: 42449138777     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc700132f     Document Type: Article

References (25)

1. (a) Dolle, R. E.; Nelson, K. H., Jr. J. Comb. Chem. 1999, 1, 235-282.
2. (b) Dolle, R. E. J. Comb. Chem. 2000, 2, 383-433.
3. (c) Dolle, R. E. J. Comb. Chem. 2001, 3, 477-517.
4. (d) Dolle, R. E. J. Comb. Chem. 2002, 4, 369-418.
5. (e) Dolle, R. E. J. Comb. Chem. 2003, 5, 693-753.
6. (f) Dolle, R. E. J. Comb. Chem. 2004, 6, 623-679.
7. (g) Dolle, R. E. J. Comb. Chem. 2005, 7, 739-798.
8. (h) Dolle, R. E.; Le Bourdonnec, B.; Morales, G. A.; Moriarty, K. J.; Salvino, J. M. J. Comb. Chem. 2006, 8, 597-635.
9. (a) Furka, A.; Sebestyen, F.; Asgedom, M.; Dibo, G. Int. J. Pept. Protein Res. 1991, 37, 487-493.
10. (b) Lam, K. S.; Salmon, S. E.; Hersh, E. M.; Hruby, V. J.; Kazmierski, W. M.; Knapp, R. J. Nature 1991, 354, 82-84.
11. (a) Aherne, W.; Garrett, M.; McDonald, E.; Workman, P. Mechanism-based high throughput screening for novel anticancer drug discovery. In Anti-cancer Drug Development; Baguley, B. C., Kerr, D. J., Eds.; Academic Press: New York, 2002, pp 249-267.
12. (b) Garrett, M. D.; Walton, M. I.; McDonald, E.; Judson, I.; Workman, P. Prog. Cell Cycle Res. 2003, 5, 145-158.
13. Mason, J. S.; Morize, I.; Menard, P. R.; Cheney, D. L.; Hulme, C.; Labaudiniere, R. F. J. Med. Chem. 1999, 42, 3251-3264.
14. Murugesan, N.; Gu, Z.; Stein, P. D.; Bisaha, S.; Spergel, S.; Girotra, R.; Lee, V. G.; Lloyd, J.; Misra, R. N.; Schmidt, J.; Mathur, A.; Stratton, L.; Kelly, Y. F.; Bird, E.; Waldron, T.; Liu, C.-K.; Zhang, R.; Lee, H.; Serafino, R.; Abboa-Offei, B.; Mathers, P.; Giancarli, M.; Seymour, A. A.; Webb, M. L.; Moreland, S.; Banish, J. C.; Hunt, J. T. J. Med. Chem. 1998, 41, 5198-5218.
15. Capdeville, R.; Buchdunger, E.; Zimmermann, J.; Matter, A. Nat. Rev. Drug Discov. 2002, 1, 493-502.
16. Xiong, Y.; Klopp, J.; Chapman, K. T. Tetrahedron Lett. 2001, 42, 8423-8427.
17. Fernandez, J.-C.; Sole-Feu, L.; Fernandez-Forner, D.; de la Figuera, N.; Forns, P.; Albericio, F. Tetrahedron Lett. 2005, 46, 581-585.
18. Chabala, J. C.; Baldwin, J. J.; Burbaum, J. J.; Chelsky, D.; Dilliard, L.; Henderson, I.; Li, G.; Ohlmeyer, M. H. J.; Rändle, T. L. Perspect. Drug Discov. Des. 1995, 2, 305-18.
19. Buckman, B. O.; Chou, Y.-L.; McCarrick, M.; Liang, A.; Lentz, D.; Mohan, R.; Morrissey, M. M.; Shaw, K. J.; Trinh, L.; Light, D. R. Bioorg. Med. Chem. Lett. 2005, 15, 2249-2252.
20. Hammarstrom, L. G. J.; Smith, D. B.; Talamas, F. X. Tetrahedron Lett. 2007, 48, 2823-2827.
21. Gutierrez, C. D.; Bavetsias, V.; McDonald, E. Tetrahedron Lett. 2005, 46, 3595-3597.
22. www.irori.com.
23. (a) Raju, B.; Kogan, P. Tetrahedron Lett. 1997, 38, 4965-4968.
24. (b) Swayze, E. Tetrahedron Lett. 1997, 38, 8465-8468.
25. Wang, S. Tetrahedron Lett. 1997, 38, 5575-5578.