Reduced expression of MAb6B4 epitopes on chondroitin sulfate proteoglycan aggrecan in perineuronal nets from cerebral cortices of SAMP10 mice: A model for age-dependent neurodegeneration

Journal of Neuroscience Research

Volumn 86, Issue 6, 2008, Pages 1316-1323

  Saitoh, Yuko ^a,b   Matsui, Fumiko ^a   Chiba, Yoichi ^a   Kawamura, Noriko ^a   Keino, Hiromi ^a   Satoh, Mamoru ^a   Kumagai, Naoko ^a   Ishii, Sanae ^a   Yoshikawa, Keisuke ^a   Shimada, Atsuyoshi ^a   Maeda, Nobuaki ^c   Oohira, Atsuhiko ^a   Hosokawa, Masanori ^a  

^a INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

^b HYOGO COLLEGE OF MEDICINE   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Aggrecan; Brain atrophy; Learning and memory; Phosphacan PTP ; Proteoglycan

Indexed keywords

EPITOPE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 6B4; PROTEOCHONDROITIN SULFATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; BRAIN CORTEX; BRAIN MATURATION; CONTROLLED STUDY; MOUSE; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; SENESCENCE ACCELERATED MOUSE;

AGGRECANS; AGING; ANIMALS; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; EPITOPES; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED STRAINS; NERVE DEGENERATION; NERVE NET; PROTEOCHONDROITIN SULFATES; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 5;

EID: 42449129642     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21582     Document Type: Article

References (39)

1. Bandtlow CE, Zimmermann DR. 2000. Proteoglycans in the developing brain: new conceptual insights for old proteins. Physiol Rev 80:1267-1290.
2. Carter TA, Greenhall JA, Yoshida S, Fuchs S, Helton R, Swaroop A, Lockhart DJ, Barlow C. 2005. Mechanisms of aging in senescence-accelerated mice. Genome Biol 6:R48.
3. Celio MR, Blumcke I. 1994. Perineuronal nets - a specialized form of extracellular matrix in the adult nervous system. Brain Res Rev 19:128-145.
4. Celio MR, Spreafico R, De Biasi S, Vitellaro-Zuccarello L. 1998. Perineuronal nets: past and present. Trends Neurosci 21:510-515.
5. Deepa SS, Carulli D, Galtrey C, Rhodes K, Fukuda J, Mikami T, Sugahara K, Fawcett JW. 2006. Composition of perineuronal net extracellular matrix in rat brain: a different disaccharide composition for the net-associated proteoglycans. J Biol Chem 281:17789-17800.
6. Dino MR, Harroch S, Hockfield S, Matthews RT. 2006. Monoclonal antibody Cat-315 detects a glycoform of receptor protein tyrosine phosphatase β/phosphacan early in CNS development that localizes to extrasynaptic sites prior to synapse formation. Neuroscience 142:1055-1069.
7. Endo T. 2005. Aberrant glycosylation of α-dystroglycan and congenital muscular dystrophies. Acta Myol 24:64-69.
8. Fujita SC, Tada Y, Murakami F, Hayashi M, Matsumura M. 1989. Glycosaminoglycan-related epitopes surrounding different subsets of mammalian central neurons. Neurosci Res 7:117-130.
9. Galtrey CM, Fawcett JW. 2007. The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system. Brain Res Rev 54:1-18.
10. Guimaraes A, Zaremba S, Hockfield S. 1990. Molecular and morphological changes in the cat lateralgeniculate nucleus and visual cortex induced by visual deprivation are revealed by monoclonal antibodies Cat-304 and Cat-301. J Neurosci 10:3014-3024.
11. Hayashi N, Miyata S, Yamada M, Kamei K, Oohira A. 2005. Neuronal expression of the chondroitin sulfate proteoglycans receptor-type protein-tyrosine phosphatase β and phosphacan. Neuroscience 131:331-348.
12. Hosokawa M, Umezawa M, Higuchi T, Takeda T. 1998. Interventions of senescence in SAM mice. J Anti Aging Med 1:27-37.
13. Köppe G, Brückner G, Brauer K, Härtig W, Bigl V. 1997. Developmental patterns of proteoglycan-containing extracellular matrix in perineuronal nets and neuropil of the postnatal rat brain. Cell Tissue Res 288:33-41.
14. Kosaka T, Heizmann CW, Fujita SC. 1992. Monoclonal antibody 473 selectively stains a population of GABAergic neurons containing the calcium-binding protein parvalbumin in the rat cerebral cortex. Exp Brain Res 89:109-114.
15. Maeda N, Hamanaka H, Shintani T, Nishiwaki T, Noda M. 1994. Multiple receptor-like protein tyrosine phosphatases in the form of chondroitin sulfate proteoglycan. FEBS Lett 354:67-70.
16. Maeda N, Matsui F, Oohira A. 1992. A chondroitin sulfate proteoglycan that is developmentally regulated in the cerebellar mossy fiber system. Dev Biol 151:564-574.
17. Matsui F, Oohira A. 1999. Proteoglycans in perineuronal net. Acta Histochem Cytochem 32:141-147.
18. Matsui F, Oohira A. 2004. Proteoglycans and injury of the central nervous system. Congenit Anom (Kyoto) 44:181-188.
19. Matsui F, Watanabe E, Oohira A. 1994. Immunological identification of two proteoglycan fragments derived from neurocan, a brain-specific chondroitin sulfate proteoglycan. Neurochem Int 25:425-431.
20. Matthews RT, Kelly GM, Zerillo CA, Gray G, Tiemeyer M, Hockfield S. 2002. Aggrecan glycoforms contribute to the molecular heterogeneity of perineuronal nets. J Neurosci 22:7536-7547.
21. Morgenstern DA, Asher RA, Fawcett JW. 2002. Chondroitin sulphate proteoglycans in the CNS injury response. Prog Brain Res 137:313-332.
22. Murakami T, Ohtsuka A. 2003. Perisynaptic barrier of proteoglycans in the mature brain and spinal cord. Arch Histol Cytol 66:195-207.
23. Oohira A, Katoh-Semba R, Watanabe E, Matsui F. 1994. Brain development and multiple molecular species of proteoglycan. Neurosci Res 20:195-207.
24. Properzi F, Fawcett JW. 2004. Proteoglycans and brain repair. News Physiol Sci 19:33-38.
25. Ruoslahti E. 1989. Proteoglycans in cell regulation. J Biol Chem 264:13369-13372.
26. Sano S, Kudo J, Fujita SC. 1993. Different subsets of CNS neurons express different glycosaminoglycan epitopes on large perineuronal proteoglycans. Brain Res 630:65-74.
27. Schwartz NB, Domowicz M. 2004. Proteoglycans in brain development. Glycoconj J 21:329-341.
28. Shimada A. 1999. Age-dependent cerebral atrophy and cognitive dysfunction in SAMP10 mice. Neurobiol Aging 20:125-136.
29. Shimada A, Hosokawa M, Ohta A, Akiguchi I, Takeda T. 1994. Localization of atrophy-prone areas in the aging mouse brain: comparison between the brain atrophy model SAM-P/10 and the normal control SAM-R/1. Neuroscience 59:859-869.
30. Shimada A, Keino H, Satoh M, Kishikawa M, Hosokawa M. 2003. Age-related loss of synapses in the frontal cortex of SAMP10 mouse: a model of cerebral degeneration. Synapse 48:198-204.
31. Shimada A, Keino H, Satoh M, Kishikawa M, Seriu N, Hosokawa M. 2002. Age-related progressive neuronal DNA damage associated with cerebral degeneration in a mouse model of accelerated senescence. J Gerontol A Biol Sci Med Sci 57:B415-B421.
32. Shimada A, Ohta A, Akiguchi I, Takeda T. 1992. Inbred SAM-P/10 as a mouse model of spontaneous, inherited brain atrophy. J Neuropathol Exp Neurol 51:440-450.
33. Shimada A, Ohta A, Akiguchi I, Takeda T. 1993. Age-related deterioration in conditional avoidance task in the SAM-P/10 mouse, an animal model of spontaneous brain atrophy. Brain Res 608:266-272.
34. Sur M, Frost DO, Hockfield S. 1988. Expression of a surface-associated antigen on Y-cells in the cat lateral geniculate nucleus is regulated by visual experience. J Neurosci 8:874-882.
35. Takeda T. 1999. Senescence-accelerated mouse (SAM): a biogerontological resource in aging research. Neurobiol Aging 20:105-110.
36. Takeda T, Hosokawa M, Takeshita S, Irino M, Higuchi K, Matsushita T, Tomita Y, Yasuhira K, Hamamoto H, Shimizu K, Ishii M, Yamamuro T. 1981. A new murine model of accelerated senescence. Mech Ageing Dev 17:183-194.
37. Viapiano MS, Matthews RT. 2006. From barriers to bridges: chondroitin sulfate proteoglycans in neuropathology. Trends Mol Med 12:488-496.
38. Watanabe E, Fujita SC, Murakami F, Hayashi M, Matsumura M. 1989. A monoclonal antibody identifies a novel epitope surrounding a subpopulation of the mammalian central neurons. Neuroscience 29:645-657.
39. Yamaguchi Y. 2000. Lecticans: organizers of the brain extracellular matrix. Cell Mol Life Science 57:276-289.