Neurotensin in the ventral pallidum increases extracellular γ-aminobutyric acid and differentially affects cue- and cocaine-primed reinstatement

Journal of Pharmacology and Experimental Therapeutics

Volumn 325, Issue 2, 2008, Pages 556-566

  Torregrossa, Mary M ^a,b   Kalivas, Peter W ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [5 (2,6 DIMETHOXYPHENYL) 1 [4 [N (3 DIMETHYLAMINOPROPYL) N METHYLCARBAMOYL] 2 ISOPROPYLPHENYL] 1H PYRAZOL 3 YLCARBONYLAMINO]ADAMANTANE 2 CARBOXYLIC ACID; 2 [[1 (7 CHLORO 4 QUINOLINYL) 5 (2,6 DIMETHOXYPHENYL) 3 PYRAZOLYL]CARBONYLAMINO] 2 ADAMANTANECARBOXYLIC ACID; 4 AMINOBUTYRIC ACID; COCAINE; NEUROTENSIN; NEUROTENSIN RECEPTOR; NEUROTENSIN[8-13]; TETRODOTOXIN; NEUROTENSIN (8 13); NEUROTENSIN (8-13); PEPTIDE FRAGMENT; PYRAZOLE DERIVATIVE; QUINOLINE DERIVATIVE;

4 AMINOBUTYRIC ACID RELEASE; AMINO ACID BRAIN LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COCAINE DEPENDENCE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; GLOBUS PALLIDUS; HISTOPATHOLOGY; MALE; MOTOR ACTIVITY; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; BRAIN; DRUG POTENTIATION; DRUG SELF ADMINISTRATION; METABOLISM; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; BRAIN; COCAINE; COCAINE-RELATED DISORDERS; GAMMA-AMINOBUTYRIC ACID; MALE; MOTOR ACTIVITY; NEUROTENSIN; PEPTIDE FRAGMENTS; PYRAZOLES; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROTENSIN; SELF ADMINISTRATION;

EID: 42449127129     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.130310     Document Type: Article

References (40)

1. Bayer VE, Towle AC, and Pickel VM (1991) Ultrastructural localization of neurotensin-like immunoreactivity within dense core vesicles in perikarya, but not terminals, colocalizing tyrosine hydroxylase in the rat ventral tegmental area. J Comp Neurol 311:179-196.
2. Binder EB, Gross RE, Nemeroff CB, and Kilts CD (2002) Effects of neurotensin receptor antagonism on latent inhibition in Sprague-Dawley rats. Psychopharmacology 161:288-295.
3. Boules M, Warrington L, Fauq A, McCormick D, and Richelson E (2001) A novel neurotensin analog blocks cocaine- and D-amphetamine-induced hyperactivity. Eur J Pharmacol 426:73-76.
4. Bourdelais A and Kalivas PW (1990) Amphetamine lowers extracellular GABA concentration in the ventral pallidum. Brain Res 516:132-136.
5. Cáceda R, Kinkead B, and Nemeroff CB (2006) Neurotensin: role in psychiatric and neurological diseases. Peptides 27:2385-2404.
6. Caillé S and Parsons LH (2004) Intravenous heroin self-administration decreases GABA efflux in the ventral pallidum: an in vivo microdialysis study in rats. Eur J Neurosci 20:593-596.
7. Caillé S and Parsons LH (2006) Cannabinoid modulation of opiate reinforcement through the ventral striatopallidal pathway. Neuropsychopharmacology 31:804-813.
8. Del-Fava F, Hasue RH, Ferreira JG, and Shammah-Lognado SJ (2007) Efferent connections of the rostral linear nucleus of the ventral tegmental area in the rat. Neuroscience 145:1059-1076.
9. Di Ciano P and Everitt BJ (2001) Dissociable effects of antagonism of NMDA and AMPA/KA receptors in the nucleus accumbens core and shell on cocaine-seeking behavior. Neuropsychopharmacology 25:341-360.
10. Felszeghy K, Espinosa JM, Scarna H, Berod A, Rostene W, and Pelaprat D (2007) Neurotensin receptor antagonist administered during cocaine withdrawal decreases locomotor sensitization and conditioned place preference. Neuropsychopharmacology 32:2601-2610.
11. Ferraro L, Antonelli T, O'Connor WT, Fuxe K, Soubrie P, and Tanganelli S (1998) The striatal neurotensin receptor modulates striatal and pallidal glutamate and GABA release: functional evidence for a pallidal glutamate-GABA interaction via the pallidal-subthalamic nucleus loop. J Neurosci 18:6977-6989.
12. Ferraro L, O'Connor WT, Antonelli T, Fuxe K, and Tanganelli S (1997) Differential effects of intrastriatal neurotensin(1-13) and neurotensin(8-13) on striatal dopamine and pallidal GABA release: a dual-probe microdialysis study in the awake rat. Eur J Neurosci 9:1838-1846.
13. Institute of Laboratory Animal Resources (1996) Guide for the Care and Use of Laboratory Animals 7th ed. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington DC.
14. Kalivas PW, Nemeroff CB, and Prange AJ (1984) Neurotensin microinjection into the nucleus accumbens antagonizes dopamine-induced increase in locomotion and rearing. Neuroscience 11:919-930.
15. Kalivas PW and Duffy P (1990) Effect of acute and daily neurotensin and enkephalin treatments on extracellular dopamine in the nucleus accumbens. J Neurosci 10:2940-2949.
16. Klitenick MA, Deutch AY, Churchill L, and Kalivas PW (1992) Topography and functional role of dopaminergic projections from the ventral mesencephalic tegmentum to the ventral pallidum. Neuroscience 50:371-386.
17. Laitinen K, Crawley JN, Mefford IN, and De Witte P (1990) Neurotensin and cholecystokinin microinjected into the ventral tegmental area modulate microdialysate concentrations of dopamine and metabolites in the posterior nucleus accumbens. Brain Res 523:342-346.
18. Martorana A, Martella G, D'Angelo V, Fusco FR, Spadoni F, Bernardi G, and Stefani A (2006) Neurotensin effects on N-type calcium currents among rat pallidal neurons: an electrophysiological and immunohistochemical study. Synapse 60:371-383.
19. McFarland K and Kalivas PW (2001) The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior. J Neurosci 21:8655-8663.
20. McFarland K, Lapish CC, and Kalivas PW (2003) Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior. J Neurosci 23:3531-3537.
21. McFarland K, Davidge SB, Lapish CC, and Kalivas PW (2004) Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior. J Neurosci 24:1551-1560.
22. Michaud JC, Gueudet C, and Soubrie P (2000) Effects of neurotensin receptor antagonists on the firing rate of rat ventral pallidum neurons. Neuroreport 11:1437-1441.
23. O'Connor WT (2001) Functional neuroanatomy of the ventral striopallidal GABA pathway: new sites of intervention in the treatment of schizophrenia. J Neurosci Methods 109:31-39.
24. Olive MF, Anton B, Micevych P, Evans CJ, and Maidment NT (1997) Presynaptic versus postsynaptic localization of mu and delta opioid receptors in dorsal and ventral striatopallidal pathways. J Neurosci 17:7471-7479.
25. Paxinos G and Watson C (1986) The Rat Brain in Stereotaxic Coordinates, Academic Press, New York.
26. Petrie KA, Schmidt D, Bubser M, Fadel J, Carraway RE, and Deutch AY (2005) Neurotensin activates GABAergic interneurons in the prefrontal cortex. J Neurosci 25:1629-1636.
27. Phillips PE, Stuber GD, Heien ML, Wightman RM, and Carelli RM (2003) Subsecond dopamine releases promotes cocaine seeking. Nature 422:614-618.
28. Rakovska A, Giovannini MG, Della Corte L, Kalfin R, Bianchi L, and Pepeu G (1998) Neurotensin modulation of acetylcholine and GABA release from the rat hippocampus: an in vivo microdialysis study. Neurochem Int 33:335-340.
29. Robledo P, Maldonado R, and Koob GF (1993) Neurotensin injected into the nucleus accumbens blocks the psychostimulant effects of cocaine but does not attenuate cocaine self-administration in the rat. Brain Res 622:105-112.
30. See RE (2002) Neural substrates of conditioned-cued relapse to drug-seeking behavior. Pharmacol Biochem Behav 71:517-529.
31. Seiden LS, Sabol KE, and Ricuarte GA (1993) Amphetamine: effects on catecholamine systems and behavior. Annu Rev Pharmacol Toxicol 33:639-677.
32. Shaham Y, Shalev U, Lu L, DeWit H, and Stewart J (2003) The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacol 168:3-20.
33. Shalev U, Grimm JW, and Shaham Y (2002) Neurobiology of relapse to heroin and cocaine seeking: a review. Pharmacol Rev 54:1-42.
34. Tang XC, McFarland K, Cagle S, and Kalivas PW (2005) Cocaine-induced reinstatement requires endogenous stimulation of mu-opioid receptors in the ventral pallidum. J Neurosci 25:4512-4520.
35. Tanganelli S, O'Connor WT, Ferraro L, Bianchi C, Beani L, Ungerstadt U, and Fuxe K (1994) Facilitation of GABA release by neurotensin is associated with a reduction of dopamine release in rat nucleus accumbens. Neuroscience 60:649-657.
36. Torregrossa MM and Kalivas PW (2007) Microdialysis and the neurochemistry of addiction. Pharmacol Biochem Behav, in press.
37. Wagstaff JD, Bush LG, Gibb JW, and Hanson GR (1994) Endogenous neurotensin antagonizes methamphetamine-enhanced dopaminergic activity. Brain Res 665:237-244.
38. Zahm DS, Zaborszky L, Alones VE, and Heimer L (1985) Evidence for the coexistence of glutamate decarboxylase and Met-enkephalin immunoreactivities in axon terminals of rat ventral pallidum. Brain Res 325:317-321.
39. Zahm DS and Heimer L (1988) Ventral striatopallidal parts of the basal ganglia in the rat: I. Neurochemical compartmentation as reflected by the distributions of neurotensin and substance P immunoreactivity. J Comp Neurol 272:516-535.
40. Zahm DS and Heimer L (1990) Two transpallidal pathways originating in the rat nucleus accumbens. J Comp Neurol 302:437-446.